STRINGSTRING
argD argD metZ metZ Smed_0167 Smed_0167 Smed_0178 Smed_0178 Smed_0196 Smed_0196 Smed_0665 Smed_0665 glyA glyA Smed_0867 Smed_0867 Smed_1109 Smed_1109 gcvP gcvP Smed_1213 Smed_1213 Smed_1454 Smed_1454 Smed_1465 Smed_1465 Smed_1469 Smed_1469 Smed_1503 Smed_1503 Smed_1744 Smed_1744 Smed_1955 Smed_1955 Smed_1974 Smed_1974 glyA-2 glyA-2 Smed_2201 Smed_2201 kbl kbl Smed_2233 Smed_2233 Smed_2317 Smed_2317 Smed_2412 Smed_2412 Smed_2419 Smed_2419 hisC hisC Smed_2578 Smed_2578 Smed_2580 Smed_2580 Smed_2619 Smed_2619 Smed_2712 Smed_2712 Smed_2880 Smed_2880 Smed_2982 Smed_2982 hisC-2 hisC-2 Smed_3160 Smed_3160 Smed_3162 Smed_3162 Smed_3509 Smed_3509
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
argDTIGRFAM: acetylornithine and succinylornithine aminotransferase; PFAM: aminotransferase class-III; KEGG: sme:SMc02138 putative acetylornithine aminotransferase protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (399 aa)
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (394 aa)
Smed_0167Aminotransferase class I and II; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aminotransferase class I and II; KEGG: sme:SMc02251 putative aminotransferase protein. (388 aa)
Smed_0178PFAM: aminotransferase class V; Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: sme:SMc02262 putative aminotransferase protein. (396 aa)
Smed_01968-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; aminotransferase class-III; KEGG: sme:SMc02272 acyl-transferase transferase protein. (470 aa)
Smed_0665PFAM: aminotransferase class I and II; KEGG: sme:SMc02393 histidinol-phosphate aminotransferase. (373 aa)
glyAGlycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (431 aa)
Smed_0867TIGRFAM: O-acetylhomoserine/O-acetylserine sulfhydrylase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: sme:SMc01809 O-acetylhomoserine (thiol)-lyase. (426 aa)
Smed_1109TIGRFAM: cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: sme:SMc02117 cystathionine beta-lyase. (469 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (954 aa)
Smed_1213PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: rle:pRL80073 putative cysteine desulfurase. (393 aa)
Smed_1454PFAM: aminotransferase class I and II; KEGG: sme:SMc00294 probable aminotransferase protein. (405 aa)
Smed_1465TIGRFAM: cysteine desulfurase, SufS subfamily; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: sme:SMc00533 putative pyridoxal-phosphate-dependent aminotransferase protein; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. (413 aa)
Smed_1469PFAM: aminotransferase class V; KEGG: sme:SMc00529 putative pyridoxal-phosphate-dependent aminotransferase protein. (402 aa)
Smed_1503Putative transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: sme:SMc00490 putative transcription regulator protein. (472 aa)
Smed_1744PFAM: aminotransferase class I and II; KEGG: sme:SMc04281 probable cobalamin biosynthesis protein pyridoxal-phosphate-dependent aminotransferase. (333 aa)
Smed_1955Putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; KEGG: sme:SMc04323 probable aminotransferase protein. (408 aa)
Smed_1974Putative transcriptional regulator, GntR family; PFAM: regulatory protein GntR HTH; aminotransferase class I and II; KEGG: sme:SMc01406 putative transcription regulator protein. (514 aa)
glyA-2Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (425 aa)
Smed_2201Cystathionine gamma-synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; KEGG: sme:SMc01666 methionine gamma-lyase. (427 aa)
kbl2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (395 aa)
Smed_2233PFAM: aminotransferase class I and II; KEGG: sme:SMc01578 aspartate aminotransferase A (transaminase) protein. (400 aa)
Smed_2317PFAM: aminotransferase class-III; KEGG: sme:SMc01534 beta alanine-pyruvate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (442 aa)
Smed_2412Aminotransferase class I and II; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: sme:SMc01969 hypothetical protein. (392 aa)
Smed_2419Cystathionine beta-lyase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: sme:SMc01976 hypothetical protein. (390 aa)
hisCTIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; KEGG: sme:SMc00710 putative histidinol-phosphate aminotransferase protein; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (368 aa)
Smed_2578Aminotransferase class-III; PFAM: aminoglycoside phosphotransferase; peptidase M23B; aminotransferase class-III; KEGG: sme:SMc00677 hypothetical protein. (1018 aa)
Smed_2580Aminotransferase class-III; PFAM: aminoglycoside phosphotransferase; aminotransferase class-III; KEGG: sme:SMc00675 hypothetical protein. (975 aa)
Smed_2619Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (392 aa)
Smed_2712Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (348 aa)
Smed_2880TIGRFAM: 5-aminolevulinic acid synthase; PFAM: aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: sme:SMc03104 probable 5-aminolevulinic acid synthase (delta-aminolevulinate synthase) (delta-ala synthetase) protein. (406 aa)
Smed_2982TIGRFAM: cysteine desulfurase family protein; PFAM: aminotransferase class V; KEGG: gvi:gll2601 probable aminotransferase. (425 aa)
hisC-2TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; KEGG: sme:SMc03885 putative histidinol-phosphate aminotransferase protein; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (351 aa)
Smed_3160PFAM: aminotransferase class I and II; KEGG: sme:SMc04386 aspartate aminotransferase B protein. (410 aa)
Smed_3162PFAM: aminotransferase class-III; KEGG: sme:SMc04388 putative omega-amino acid--pyruvate aminotransferase protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (445 aa)
Smed_3509Tyrosine transaminase; PFAM: aminotransferase class I and II; KEGG: sme:SMc00387 tyrosine aminotransferase protein. (389 aa)
Your Current Organism:
Sinorhizobium medicae
NCBI taxonomy Id: 366394
Other names: Ensifer medicae WSM419, S. medicae WSM419, Sinorhizobium medicae WSM419
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