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| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. (445 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (344 aa) |
| | acsA | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (646 aa) |
| | lysS | KEGG: ccr:CC_0084 lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: Lysyl-tRNA synthetase class 1c; Belongs to the class-I aminoacyl-tRNA synthetase family. (552 aa) |
| | Caul_0171 | PFAM: Glutathione S-transferase domain; KEGG: ccr:CC_0147 glutathione S-transferase family protein. (200 aa) |
| | gshB | KEGG: ccr:CC_0141 glutathione synthetase; TIGRFAM: glutathione synthetase; PFAM: glutathione synthetase domain protein; glutathione synthetase ATP-binding; RimK domain protein ATP-grasp; Belongs to the prokaryotic GSH synthase family. (317 aa) |
| | Caul_0203 | KEGG: ccr:CC_0128 hypothetical protein. (66 aa) |
| | Caul_0212 | PFAM: AMP-dependent synthetase and ligase; KEGG: ccr:CC_0192 medium-chain-fatty-acid--CoA ligase. (539 aa) |
| | sucC | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (399 aa) |
| | sucD | succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa) |
| | Caul_0372 | Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. (452 aa) |
| | Caul_0423 | PFAM: AMP-dependent synthetase and ligase; KEGG: bja:blr2951 acyl-CoA synthetase. (509 aa) |
| | Caul_0495 | PFAM: AMP-dependent synthetase and ligase; KEGG: ccr:CC_0922 acyl-CoA synthase. (553 aa) |
| | Caul_0545 | PFAM: AMP-dependent synthetase and ligase; KEGG: ppu:PP_2709 long-chain-fatty-acid--CoA ligase, putative. (484 aa) |
| | Caul_0579 | PFAM: AMP-dependent synthetase and ligase; KEGG: ccr:CC_0922 acyl-CoA synthase. (521 aa) |
| | purA | Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (428 aa) |
| | Caul_0711 | Cobalt chelatase, pCobS small subunit; KEGG: ccr:CC_3021 cobalamin biosynthesis protein; TIGRFAM: cobalt chelatase, pCobS small subunit; PFAM: ATPase associated with various cellular activities AAA_5. (335 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (320 aa) |
| | Caul_0762 | Lysine--tRNA ligase; PFAM: tRNA synthetase class II (D K and N); KEGG: ccr:CC_0720 asparaginyl-tRNA synthetase, putative. (349 aa) |
| | Caul_0775 | PFAM: 5-formyltetrahydrofolate cyclo-ligase; KEGG: ccr:CC_3245 5-formyltetrahydrofolate cyclo-ligase; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (203 aa) |
| | Caul_0814 | PFAM: AMP-dependent synthetase and ligase; KEGG: ccr:CC_3188 4-coumarate-CoA ligase, putative. (517 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (364 aa) |
| | Caul_1023 | ATPase, FliI/YscN family; KEGG: ccr:CC_3040 flagellum-specific ATP synthase FliI; TIGRFAM: ATPase, FliI/YscN family; PFAM: H+transporting two-sector ATPase alpha/beta subunit central region; H+transporting two-sector ATPase alpha/beta subunit domain protein; SMART: AAA ATPase. (445 aa) |
| | carA | TIGRFAM: carbamoyl-phosphate synthase, small subunit; PFAM: glutamine amidotransferase class-I; Carbamoyl-phosphate synthase small chain; KEGG: ccr:CC_2834 carbamoyl-phosphate synthase, small subunit; Belongs to the CarA family. (388 aa) |
| | queC | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (250 aa) |
| | Caul_1135 | PFAM: AMP-dependent synthetase and ligase; KEGG: mlo:mlr1843 acyl-CoA synthase. (517 aa) |
| | pheT | KEGG: ccr:CC_1043 phenylalanyl-tRNA synthetase beta chain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit. (812 aa) |
| | pheS | TIGRFAM: phenylalanyl-tRNA synthetase, alpha subunit; PFAM: phenylalanyl-tRNA synthetase class IIc; aminoacyl tRNA synthetase class II domain protein; KEGG: ccr:CC_1044 phenylalanyl-tRNA synthetase alpha chain; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (362 aa) |
| | Caul_1308 | PFAM: protein of unknown function DUF1486; KEGG: mpa:MAP2016 hypothetical protein. (158 aa) |
| | Caul_1315 | PFAM: AMP-dependent synthetase and ligase; KEGG: ccr:CC_0922 acyl-CoA synthase. (965 aa) |
| | Caul_1347 | PFAM: AMP-dependent synthetase and ligase; KEGG: ccr:CC_0944 long-chain fatty-acid-CoA ligase. (512 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (883 aa) |
| | Caul_1397 | KEGG: ccr:CC_2529 alanyl-tRNA synthetase. (36 aa) |
| | Caul_1405 | PFAM: glutathionylspermidine synthase; KEGG: ccr:CC_2361 hypothetical protein. (385 aa) |
| | gatC | glutamyl-tRNA(Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (95 aa) |
| | gatA | glutamyl-tRNA(Gln) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (490 aa) |
| | gatB | glutamyl-tRNA(Gln) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (499 aa) |
| | Caul_1531 | PFAM: O-antigen polymerase; KEGG: ccr:CC_2429 hypothetical protein. (419 aa) |
| | Caul_1595 | PFAM: O-antigen polymerase; KEGG: mmr:Mmar10_1688 O-antigen polymerase. (467 aa) |
| | Caul_1668 | PFAM: GumN family protein; KEGG: ccr:CC_2229 hypothetical protein. (294 aa) |
| | Caul_1688 | PFAM: AMP-dependent synthetase and ligase; KEGG: ccr:CC_1165 acyl-CoA synthase. (568 aa) |
| | Caul_1705 | PFAM: carboxyl transferase; KEGG: ccr:CC_1975 propionyl-CoA carboxylase beta chain. (510 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (569 aa) |
| | Caul_1769 | TIGRFAM: DNA ligase D; DNA ligase D, 3'-phosphoesterase domain protein; DNA polymerase LigD, polymerase domain protein; DNA polymerase LigD, ligase domain protein; PFAM: DNA primase small subunit; ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: rpc:RPC_3685 ATP dependent DNA ligase. (918 aa) |
| | Caul_1875 | Propionyl-CoA carboxylase; PFAM: carboxyl transferase; KEGG: swi:Swit_2162 propionyl-CoA carboxylase. (538 aa) |
| | Caul_1876 | PFAM: biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: swi:Swit_2163 carbamoyl-phosphate synthase L chain, ATP-binding. (621 aa) |
| | Caul_1907 | PFAM: AMP-dependent synthetase and ligase; KEGG: bxe:Bxe_C0592 putative AMP-dependent synthetase and ligase. (543 aa) |
| | Caul_1986 | PFAM: asparagine synthase; KEGG: ccr:CC_2711 hypothetical protein. (583 aa) |
| | Caul_1999 | PFAM: UBA/THIF-type NAD/FAD binding protein; KEGG: bvi:Bcep1808_0170 UBA/ThiF-type NAD/FAD binding protein. (470 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (907 aa) |
| | Caul_2153 | PFAM: AMP-dependent synthetase and ligase; KEGG: ccr:CC_1321 long-chain-fatty-acid--CoA ligase. (591 aa) |
| | glyQ | KEGG: ccr:CC_1341 glycyl-tRNA synthetase alpha chain; TIGRFAM: glycyl-tRNA synthetase, alpha subunit; PFAM: glycyl-tRNA synthetase alpha subunit. (302 aa) |
| | glyS | KEGG: ccr:CC_1342 glycyl-tRNA synthetase beta chain; TIGRFAM: glycyl-tRNA synthetase, beta subunit. (728 aa) |
| | Caul_2198 | PFAM: protein of unknown function DUF404; protein of unknown function DUF407; KEGG: ccr:CC_1602 hypothetical protein. (507 aa) |
| | guaA | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. (528 aa) |
| | Caul_2241 | PFAM: asparagine synthase; KEGG: ccr:CC_2711 hypothetical protein. (568 aa) |
| | Caul_2308 | KEGG: hne:HNE_1482 hypothetical protein. (424 aa) |
| | Caul_2430 | PFAM: AMP-dependent synthetase and ligase; KEGG: mpt:Mpe_A2668 long-chain acyl-CoA synthetases (AMP-forming). (483 aa) |
| | Caul_2482 | TIGRFAM: 2'-5' RNA ligase; PFAM: Phosphoesterase HXTX; KEGG: pol:Bpro_2442 2',5' RNA ligase. (189 aa) |
| | purM | KEGG: ccr:CC_1703 phosphoribosylformylglycinamidine cyclo-ligase; TIGRFAM: phosphoribosylformylglycinamidine cyclo-ligase; PFAM: AIR synthase related protein; AIR synthase related protein domain protein. (341 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (609 aa) |
| | Caul_2564 | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa) |
| | Caul_2565 | acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (171 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (419 aa) |
| | Caul_2638 | PFAM: protein of unknown function DUF403; protein of unknown function DUF404; protein of unknown function DUF407; KEGG: bbt:BBta_2948 hypothetical protein. (843 aa) |
| | Caul_2753 | PFAM: AMP-dependent synthetase and ligase; KEGG: ccr:CC_1733 Aas bifunctional protein, putative. (517 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (550 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (474 aa) |
| | Caul_2818 | TIGRFAM: biotin--acetyl-CoA-carboxylase ligase; PFAM: biotin protein ligase domain protein; biotin/lipoate A/B protein ligase; KEGG: ccr:CC_1936 biotin protein ligase. (250 aa) |
| | Caul_2853 | TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: ccr:CC_1969 glutamine synthetase, class I. (469 aa) |
| | Caul_2860 | PFAM: AMP-dependent synthetase and ligase; KEGG: ccr:CC_0922 acyl-CoA synthase. (535 aa) |
| | bioD | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (230 aa) |
| | Caul_2951 | PFAM: AMP-dependent synthetase and ligase; KEGG: rfr:Rfer_2145 AMP-dependent synthetase and ligase. (577 aa) |
| | Caul_2972 | PFAM: protein of unknown function UPF0005; KEGG: swi:Swit_0849 protein of unknown function UPF0005; Belongs to the BI1 family. (237 aa) |
| | Caul_2999 | PFAM: carboxyl transferase; KEGG: ccr:CC_1975 propionyl-CoA carboxylase beta chain. (510 aa) |
| | Caul_3000 | PFAM: biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; RimK domain protein ATP-grasp; KEGG: ccr:CC_2179 propionyl-CoA carboxylase, alpha subunit. (669 aa) |
| | ligA | DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA. (792 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (474 aa) |
| | panC | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (290 aa) |
| | Caul_3151 | Carbamoyl-phosphate synthase L chain ATP-binding; PFAM: biotin/lipoyl attachment domain-containing protein; ATP-dependent carboxylate-amine ligase domain protein ATP-grasp; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; KEGG: ccr:CC_2168 putative propionyl-CoA carboxylase alpha chain. (657 aa) |
| | Caul_3154 | Propionyl-CoA carboxylase; PFAM: carboxyl transferase; KEGG: ccr:CC_2170 propionyl-CoA carboxylase beta chain. (535 aa) |
| | Caul_3163 | PFAM: biotin/lipoyl attachment domain-containing protein; Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; RimK domain protein ATP-grasp; KEGG: ccr:CC_2179 propionyl-CoA carboxylase, alpha subunit. (669 aa) |
| | Caul_3205 | PFAM: glutamyl-tRNA synthetase class Ic; KEGG: ccr:CC_2205 glutamyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (279 aa) |
| | Caul_3247 | PFAM: AMP-dependent synthetase and ligase; KEGG: pla:Plav_1034 AMP-dependent synthetase and ligase. (497 aa) |
| | Caul_3404 | D-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (331 aa) |
| | Caul_3420 | PFAM: Amidase; KEGG: ccr:CC_2473 amidase. (543 aa) |
| | purC | KEGG: ccr:CC_2491 phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. (252 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase, purS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assi [...] (79 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (220 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (737 aa) |
| | Caul_3540 | PFAM: AMP-dependent synthetase and ligase; KEGG: ccr:CC_2299 acyl-CoA synthase. (596 aa) |
| | Caul_3543 | PFAM: O-antigen polymerase; KEGG: ccr:CC_2301 hypothetical protein. (418 aa) |
| | ddl | D-alanine--D-alanine ligase; Cell wall formation. (322 aa) |
| | murC | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (472 aa) |
| | murD | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (469 aa) |
| | murF | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (472 aa) |
| | murE | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (485 aa) |
| | Caul_3713 | TIGRFAM: amidohydrolase, AtzE family; PFAM: Amidase; KEGG: ccr:CC_2613 pyrazinamidase/nicotinamidase. (469 aa) |
| | Caul_3714 | KEGG: ccr:CC_2614 hypothetical protein. (133 aa) |
| | Caul_3944 | Glutamate--putrescine ligase; PFAM: glutamine synthetase catalytic region; KEGG: ccr:CC_3130 glutamine synthetase family protein. (466 aa) |
| | Caul_3952 | PFAM: glutamine synthetase catalytic region; KEGG: ccr:CC_3138 glutamine synthetase family protein. (459 aa) |
| | Caul_3975 | PFAM: AMP-dependent synthetase and ligase; KEGG: ccr:CC_0966 long-chain-fatty-acid--CoA ligase, putative. (530 aa) |
| | Caul_4012 | PFAM: AMP-dependent synthetase and ligase; KEGG: swi:Swit_2237 AMP-dependent synthetase and ligase. (535 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). (969 aa) |
| | Caul_4122 | Hypothetical protein; KEGG: rru:Rru_A0074 helicase-like. (172 aa) |
| | Caul_4144 | Cobalt chelatase, pCobT subunit; KEGG: ccr:CC_0672 cobalamin biosynthesis protein; TIGRFAM: cobalt chelatase, pCobT subunit; PFAM: Cobalt chelatase CobT subunit; SMART: von Willebrand factor type A. (647 aa) |
| | carB | TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: ccr:CC_2900 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family. (1105 aa) |
| | Caul_4321 | PFAM: protein of unknown function DUF1508; KEGG: ccr:CC_2965 hypothetical protein. (59 aa) |
| | Caul_4340 | PFAM: AMP-dependent synthetase and ligase; KEGG: ccr:CC_3338 feruloyl-CoA synthase. (620 aa) |
| | Caul_4356 | PFAM: AMP-dependent synthetase and ligase; KEGG: ccr:CC_0391 feruloyl-CoA synthase. (603 aa) |
| | atpB | ATP synthase F0, A subunit; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (257 aa) |
| | atpE | H+transporting two-sector ATPase C subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (74 aa) |
| | atpF | H+transporting two-sector ATPase B/B' subunit; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (199 aa) |
| | atpF-2 | H+transporting two-sector ATPase B/B' subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (171 aa) |
| | argS | KEGG: ccr:CC_3359 arginyl-tRNA synthetase; TIGRFAM: arginyl-tRNA synthetase. (613 aa) |
| | tilS | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (455 aa) |
| | Caul_4450 | TIGRFAM: allophanate hydrolase; PFAM: Amidase; KEGG: ccr:CC_1830 amidase. (624 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). (659 aa) |
| | cysS | KEGG: ccr:CC_0460 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. (462 aa) |
| | purD | KEGG: ccr:CC_0297 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine--glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. (428 aa) |
| | Caul_4604 | PFAM: AMP-dependent synthetase and ligase; KEGG: swi:Swit_1599 AMP-dependent synthetase and ligase. (492 aa) |
| | Caul_4680 | PFAM: tRNA synthetase class II (G H P and S); KEGG: ccr:CC_3512 ATP phosphoribosyltransferase regulatory subunit. (380 aa) |
| | hisS | KEGG: ccr:CC_3513 histidyl-tRNA synthetase; TIGRFAM: histidyl-tRNA synthetase; PFAM: tRNA synthetase class II (G H P and S); Anticodon-binding domain protein. (498 aa) |
| | atpC | H+transporting two-sector ATPase delta/epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (86 aa) |
| | atpD | ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (542 aa) |
| | atpG | ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (294 aa) |
| | atpA | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (510 aa) |
| | atpH | ATP synthase F1, delta subunit; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (196 aa) |
| | argG | PFAM: argininosuccinate synthase; KEGG: ccr:CC_0129 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (407 aa) |
| | Caul_4801 | PFAM: O-antigen polymerase; KEGG: rsq:Rsph17025_1973 O-antigen polymerase. (440 aa) |
| | Caul_4898 | PFAM: ATP dependent DNA ligase domain protein; ATP dependent DNA ligase; KEGG: ccr:CC_3610 DNA ligase, ATP-dependent, putative. (539 aa) |
| | nadE | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (683 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (308 aa) |
| | Caul_4979 | KEGG: ccr:CC_3541 bifunctional protein (dihydrofolate synthase / folylpolyglutamate synthase); TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein. (437 aa) |
| | Caul_4993 | PFAM: protein of unknown function UPF0005; KEGG: ccr:CC_3663 conserved hypothetical protein; Belongs to the BI1 family. (248 aa) |
| | Caul_4995 | 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family. (178 aa) |
| | leuS | TIGRFAM: leucyl-tRNA synthetase; KEGG: ccr:CC_3749 leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (861 aa) |
| | Caul_5047 | KEGG: ccr:CC_3732 hypothetical protein. (247 aa) |
| | Caul_5055 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: ccr:CC_3726 molybdopterin biosynthesis protein MoeB. (250 aa) |
