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Caul_0125 Caul_0125 Caul_0126 Caul_0126 Caul_0130 Caul_0130 Caul_0249 Caul_0249 Caul_0423 Caul_0423 Caul_0440 Caul_0440 Caul_0446 Caul_0446 Caul_0450 Caul_0450 Caul_0577 Caul_0577 accA accA Caul_0813 Caul_0813 Caul_0993 Caul_0993 Caul_1001 Caul_1001 Caul_1270 Caul_1270 Caul_1347 Caul_1347 Caul_1370 Caul_1370 Caul_1696 Caul_1696 Caul_1886 Caul_1886 Caul_1887 Caul_1887 Caul_1891 Caul_1891 Caul_1892 Caul_1892 Caul_1894 Caul_1894 Caul_1897 Caul_1897 Caul_1904 Caul_1904 Caul_1925 Caul_1925 Caul_1953 Caul_1953 Caul_2153 Caul_2153 Caul_2430 Caul_2430 Caul_2517 Caul_2517 Caul_2518 Caul_2518 Caul_2520 Caul_2520 Caul_2564 Caul_2564 Caul_2565 Caul_2565 Caul_2720 Caul_2720 fabZ fabZ Caul_2916 Caul_2916 Caul_2938 Caul_2938 fabH fabH Caul_3052 Caul_3052 Caul_3064 Caul_3064 Caul_3239 Caul_3239 Caul_3311 Caul_3311 Caul_3576 Caul_3576 Caul_3619 Caul_3619 Caul_3873 Caul_3873 Caul_4010 Caul_4010 Caul_4071 Caul_4071 Caul_4414 Caul_4414 Caul_4465 Caul_4465 Caul_4515 Caul_4515 Caul_4519 Caul_4519 Caul_4745 Caul_4745 Caul_4752 Caul_4752 accD accD fabA fabA Caul_5061 Caul_5061 Caul_5064 Caul_5064
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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Your Input:
Caul_0125PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: ccr:CC_0076 enoyl-CoA hydratase / 3-hydroxyacyl-CoA dehydrogenase / 3-hydroxybutyryl-CoA epimerase. (732 aa)
Caul_0126acetyl-CoA acetyltransferase; KEGG: ccr:CC_0077 fatty oxidation complex, beta subunit, putative; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
Caul_0130PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: ccr:CC_0079 acyl-CoA dehydrogenase, long-chain specific. (387 aa)
Caul_0249PFAM: Enoyl-CoA hydratase/isomerase; KEGG: ccr:CC_0353 enoyl-CoA hydratase/isomerase family protein; Belongs to the enoyl-CoA hydratase/isomerase family. (286 aa)
Caul_0423PFAM: AMP-dependent synthetase and ligase; KEGG: bja:blr2951 acyl-CoA synthetase. (509 aa)
Caul_0440PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: pla:Plav_0158 short-chain dehydrogenase/reductase SDR. (275 aa)
Caul_0446PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: swi:Swit_1598 acyl-CoA dehydrogenase domain protein. (380 aa)
Caul_0450PFAM: Thiolase; KEGG: swi:Swit_4119 propanoyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (396 aa)
Caul_0577PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: xau:Xaut_1623 short-chain dehydrogenase/reductase SDR. (246 aa)
accAacetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (320 aa)
Caul_0813PFAM: Enoyl-CoA hydratase/isomerase; 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase NAD-binding; KEGG: ccr:CC_3189 fatty oxidation complex, alpha subunit; Belongs to the enoyl-CoA hydratase/isomerase family. (692 aa)
Caul_0993PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; 3-beta hydroxysteroid dehydrogenase/isomerase; Male sterility domain; KR domain protein; KEGG: xau:Xaut_1016 short-chain dehydrogenase/reductase SDR. (246 aa)
Caul_1001KEGG: ccr:CC_0894 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
Caul_1270KEGG: ccr:CC_3111 thiolase family protein; Belongs to the thiolase-like superfamily. Thiolase family. (406 aa)
Caul_1347PFAM: AMP-dependent synthetase and ligase; KEGG: ccr:CC_0944 long-chain fatty-acid-CoA ligase. (512 aa)
Caul_1370PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: afw:Anae109_3255 short-chain dehydrogenase/reductase SDR. (271 aa)
Caul_1696KEGG: bpd:BURPS668_3547 beta-ketoadipyl CoA thiolase; TIGRFAM: acetyl-CoA acetyltransferase; beta-ketoadipyl CoA thiolase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
Caul_1886PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: bxe:Bxe_C0617 putative acyl-CoA dehydrogenase. (432 aa)
Caul_1887PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; KEGG: rpa:RPA0896 putative 3-oxoacyl-acyl carrier protein reductase. (243 aa)
Caul_1891PFAM: short-chain dehydrogenase/reductase SDR; KEGG: bxe:Bxe_C0589 putative short-chain dehydrogenase/reductase. (259 aa)
Caul_1892PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: bxe:Bxe_C0602 putative acyl-CoA dehydrogenase. (378 aa)
Caul_1894PFAM: acyl-CoA dehydrogenase domain protein; KEGG: bxe:Bxe_C0604 putative acyl-CoA dehydrogenase. (337 aa)
Caul_1897TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: eba:p2A394 DitO-like thiolase, possibly related to diterpenoid metabolism; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
Caul_1904PFAM: Enoyl-CoA hydratase/isomerase; KEGG: bxe:Bxe_C0643 putative enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (264 aa)
Caul_1925PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bxe:Bxe_C0610 putative short-chain dehydrogenase/reductase. (288 aa)
Caul_1953KEGG: bxe:Bxe_B0739 thiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
Caul_2153PFAM: AMP-dependent synthetase and ligase; KEGG: ccr:CC_1321 long-chain-fatty-acid--CoA ligase. (591 aa)
Caul_2430PFAM: AMP-dependent synthetase and ligase; KEGG: mpt:Mpe_A2668 long-chain acyl-CoA synthetases (AMP-forming). (483 aa)
Caul_2517TIGRFAM: malonyl CoA-acyl carrier protein transacylase; PFAM: Acyl transferase; KEGG: ccr:CC_1674 malonyl CoA-acyl carrier protein transacylase. (314 aa)
Caul_25183-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (246 aa)
Caul_25203-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (426 aa)
Caul_2564acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (447 aa)
Caul_2565acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (171 aa)
Caul_2720PFAM: short-chain dehydrogenase/reductase SDR; KR domain protein; KEGG: bja:blr5975 putative oxidoreductase. (256 aa)
fabZBeta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (163 aa)
Caul_2916KEGG: ccr:CC_1432 thiolase family protein; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
Caul_2938Stearoyl-CoA 9-desaturase; PFAM: fatty acid desaturase; KEGG: pol:Bpro_5328 stearoyl-CoA 9-desaturase. (295 aa)
fabH3-oxoacyl-(acyl-carrier-protein) synthase III; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (325 aa)
Caul_3052PFAM: Enoyl-CoA hydratase/isomerase; KEGG: ccr:CC_1352 enoyl-CoA hydratase/isomerase family protein. (350 aa)
Caul_3064PFAM: 2-nitropropane dioxygenase NPD; KEGG: ccr:CC_1570 hypothetical protein. (311 aa)
Caul_3239Propanoyl-CoA C-acyltransferase; KEGG: ccr:CC_1432 thiolase family protein; Belongs to the thiolase-like superfamily. Thiolase family. (398 aa)
Caul_3311KEGG: rpd:RPD_1858 putative acetyl-CoA acetyltransferase. (494 aa)
Caul_3576PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: ccr:CC_2328 acyl-CoA dehydrogenase family protein. (387 aa)
Caul_3619KEGG: ccr:CC_0265 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (412 aa)
Caul_3873PFAM: acyl-CoA dehydrogenase domain protein; KEGG: hne:HNE_1134 acyl-CoA dehydrogenase family protein. (406 aa)
Caul_4010KEGG: acr:Acry_1576 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (390 aa)
Caul_4071PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: ccr:CC_0690 acyl-CoA dehydrogenase family protein. (435 aa)
Caul_4414PFAM: 2-nitropropane dioxygenase NPD; KEGG: ccr:CC_3379 hypothetical protein. (321 aa)
Caul_4465PFAM: Enoyl-CoA hydratase/isomerase; KEGG: sal:Sala_0941 enoyl-CoA hydratase/isomerase; Belongs to the enoyl-CoA hydratase/isomerase family. (252 aa)
Caul_4515KEGG: ccr:CC_0510 acetyl-CoA acetyltransferase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (391 aa)
Caul_4519TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; KEGG: sal:Sala_0110 acetyl-CoA C-acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (423 aa)
Caul_4745PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase type 2 domain; KEGG: ccr:CC_3454 acyl-CoA dehydrogenase family protein. (430 aa)
Caul_4752acetyl-CoA acetyltransferase; KEGG: ccr:CC_3462 thiolase family protein; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (395 aa)
accDacetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (308 aa)
fabABeta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (171 aa)
Caul_5061PFAM: Beta-ketoacyl synthase; KEGG: ccr:CC_3719 3-oxoacyl-(acyl-carrier-protein) synthase I; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (404 aa)
Caul_5064PFAM: short-chain dehydrogenase/reductase SDR; KEGG: ccr:CC_3717 enoyl-(acyl-carrier-protein) reductase. (271 aa)
Your Current Organism:
Caulobacter sp. K31
NCBI taxonomy Id: 366602
Other names: C. sp. K31
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