(35 nodes) Mixed, incl. Copper ion binding, and Copper ion transport network (Neurospora crassa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NCU11216	HMA domain-containing protein. (74 aa)
	cmt	Metallothionein; Belongs to the metallothionein superfamily. Type 8 family. (26 aa)
	lacc	Laccase; Lignin degradation and detoxification of lignin-derived products; Belongs to the multicopper oxidase family. (619 aa)
	NCU03498	Lcc3; Belongs to the multicopper oxidase family. (693 aa)
	NCU03497	Plasma membrane iron permease. (422 aa)
	NCU03368	HMA domain-containing protein. (97 aa)
	NCU01419	Quinone oxidoreductase. (338 aa)
	NCU01314	Uncharacterized protein. (123 aa)
	NCU01092	3-oxoacyl-(Acyl-carrier-protein) reductase. (314 aa)
	NCU03351	Uncharacterized protein. (937 aa)
	NCU05113	Laccase; Belongs to the multicopper oxidase family. (595 aa)
	NCU04076	Copper resistance-associated P-type ATPase. (1292 aa)
	NCU04593	Lcc9; Belongs to the multicopper oxidase family. (544 aa)
	NCU09279	Laccase; Belongs to the multicopper oxidase family. (601 aa)
	NCU09023	Laccase 2; Belongs to the multicopper oxidase family. (700 aa)
	NCU07531	Copper-transporting ATPase. (875 aa)
	NCU04933	Nucleoside-diphosphate-sugar epimerase. (277 aa)
	NCU08179	Glyco_hydro_79C domain-containing protein. (486 aa)
	NCU04830	Copper-fist domain-containing protein. (434 aa)
	NCU05604	Laccase-1; Belongs to the multicopper oxidase family. (607 aa)
	per-1	Polyketide synthase. (2206 aa)
	NCU08804	Solute carrier family 40 protein; May be involved in iron transport and iron homeostasis. Belongs to the ferroportin (FP) (TC 2.A.100) family. SLC40A subfamily. (585 aa)
	NCU07920	Lcc2; Belongs to the multicopper oxidase family. (739 aa)
	NCU07823	Scytalone dehydratase; Belongs to the scytalone dehydratase family. (174 aa)
	gwt1	GPI-anchored wall transfer protein 1; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. (504 aa)
	NCU00526	Lcc1. (604 aa)
	tcu-1	Ctr copper transporter. (254 aa)
	pex2	Peroxisomal biogenesis factor 2. (639 aa)
	tcu-3	Copper transporter. (185 aa)
	NCU02009	FreB protein. (647 aa)
	NCU08341	CLAP1. (1181 aa)
	tnr-1	Tetrahydroxynaphthalene reductase. (331 aa)
	NCU04269	Aspartyl proteinase, variant 1; Belongs to the peptidase A1 family. (481 aa)
	tcu-2	TCU-2. (200 aa)
	NCU10852	Beta-hexosaminidase. (628 aa)

Your Current Organism:

Neurospora crassa

NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NCU00526	NCU01314	Q7SDL8	Q1K7V5	Lcc1.	Uncharacterized protein.	0.595
NCU00526	NCU03351	Q7SDL8	Q7RXE3	Lcc1.	Uncharacterized protein.	0.551
NCU00526	NCU03497	Q7SDL8	Q1K4N9	Lcc1.	Plasma membrane iron permease.	0.498
NCU00526	NCU04933	Q7SDL8	Q7S3T4	Lcc1.	Nucleoside-diphosphate-sugar epimerase.	0.706
NCU01092	NCU07823	Q1K883	Q7SBE1	3-oxoacyl-(Acyl-carrier-protein) reductase.	Scytalone dehydratase; Belongs to the scytalone dehydratase family.	0.400
NCU01314	NCU00526	Q1K7V5	Q7SDL8	Uncharacterized protein.	Lcc1.	0.595
NCU01314	NCU03351	Q1K7V5	Q7RXE3	Uncharacterized protein.	Uncharacterized protein.	0.538
NCU01314	NCU04933	Q1K7V5	Q7S3T4	Uncharacterized protein.	Nucleoside-diphosphate-sugar epimerase.	0.706
NCU01419	NCU09023	Q1K6M1	Q7S2V2	Quinone oxidoreductase.	Laccase 2; Belongs to the multicopper oxidase family.	0.403
NCU03351	NCU00526	Q7RXE3	Q7SDL8	Uncharacterized protein.	Lcc1.	0.551
NCU03351	NCU01314	Q7RXE3	Q1K7V5	Uncharacterized protein.	Uncharacterized protein.	0.538
NCU03351	NCU04933	Q7RXE3	Q7S3T4	Uncharacterized protein.	Nucleoside-diphosphate-sugar epimerase.	0.706
NCU03368	NCU04076	Q1K4Z9	Q7RZE4	HMA domain-containing protein.	Copper resistance-associated P-type ATPase.	0.866
NCU03368	NCU04830	Q1K4Z9	Q7S6K5	HMA domain-containing protein.	Copper-fist domain-containing protein.	0.446
NCU03368	NCU07531	Q1K4Z9	Q7S316	HMA domain-containing protein.	Copper-transporting ATPase.	0.866
NCU03368	NCU08341	Q1K4Z9	Q7SGS2	HMA domain-containing protein.	CLAP1.	0.867
NCU03368	NCU11216	Q1K4Z9	A7UW07	HMA domain-containing protein.	HMA domain-containing protein.	0.866
NCU03368	tcu-1	Q1K4Z9	Q7SEA4	HMA domain-containing protein.	Ctr copper transporter.	0.534
NCU03368	tcu-2	Q1K4Z9	V5IPK5	HMA domain-containing protein.	TCU-2.	0.476
NCU03368	tcu-3	Q1K4Z9	Q7SF24	HMA domain-containing protein.	Copper transporter.	0.424

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