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| | rpa-3 | Replication protein A-3. (108 aa) |
| | mus-9 | Phosphatidyl inositol 3-kinase; Belongs to the PI3/PI4-kinase family. (2492 aa) |
| | msh4 | MutS ortholog 4 protein. (1318 aa) |
| | NCU11219 | A/G-specific adenine glycosylase. (851 aa) |
| | NCU11220 | A/G-specific adenine glycosylase. (678 aa) |
| | dnr-8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (394 aa) |
| | NCU10467 | Replication factor C subunit 4. (357 aa) |
| | cdc7 | Cell cycle protein kinase. (526 aa) |
| | NCU10125 | Rhodanese domain-containing protein. (172 aa) |
| | NCU01771 | DNA repair protein rhp57. (510 aa) |
| | NCU01218 | Chalcone_isomerase domain-containing protein. (391 aa) |
| | msh-2 | DNA mismatch repair protein msh-2; Involved in post-replicative DNA-mismatch repair. Binds to mismatch-containing DNA (By similarity). (937 aa) |
| | uvs-2 | Postreplication repair E3 ubiquitin-protein ligase rad18; E3 RING-finger protein, member of the UBC2/RAD6 epistasis group. Associates to the E2 ubiquitin conjugating enzyme mus-8/ubc2 to form the mus-8/ubc2-uvs-2/rad18 ubiquitin ligase complex involved in postreplicative repair (PRR) of damaged DNA. (501 aa) |
| | NCU03528 | DNA polymerase delta subunit 4. (241 aa) |
| | NCU01514 | Mitochondrial dicarboxylate carrier; Belongs to the mitochondrial carrier (TC 2.A.29) family. (345 aa) |
| | prk-8 | Serine/threonine-protein kinase MAK. (796 aa) |
| | NCU01746 | Uncharacterized protein. (177 aa) |
| | NCU03924 | DNA repair protein Rtt107. (847 aa) |
| | NTH1 | Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (835 aa) |
| | NCU01365 | ATP dependent DNA ligase domain-containing protein. (1072 aa) |
| | NCU08938 | DNA-3-methyladenine glycosylase. (468 aa) |
| | NCU01370 | Uncharacterized protein. (603 aa) |
| | NCU04327 | DNA helicase; Belongs to the MCM family. (882 aa) |
| | mrc1 | MRC1. (1464 aa) |
| | spo11 | Meiosis-specific topoisomerase Spo11. (466 aa) |
| | NCU03763 | DNA polymerase delta subunit 2. (525 aa) |
| | rpa-1 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (610 aa) |
| | NCU03597 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (667 aa) |
| | NCU01323 | Structural maintenance of chromosomes protein. (1263 aa) |
| | NCU01321 | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (602 aa) |
| | pold-1 | DNA polymerase. (1104 aa) |
| | NCU01171 | DNA helicase; Belongs to the MCM family. (724 aa) |
| | mus-26 | MUS26. (299 aa) |
| | mus-27 | Chromosome segregation protein. (879 aa) |
| | NCU05385 | MutL_C domain-containing protein. (937 aa) |
| | NCU05433 | Uncharacterized protein. (412 aa) |
| | NCU08427 | Activator 1 subunit 3. (389 aa) |
| | upr-1 | DNA polymerase. (1938 aa) |
| | mei-3 | DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (353 aa) |
| | NCU06833 | UvrD_C_2 domain-containing protein. (722 aa) |
| | NCU03765 | 3'-5' exonuclease/helicase. (753 aa) |
| | NCU00424 | Spo76 protein. (1595 aa) |
| | mus-25 | DNA repair and recombination protein RAD54. (835 aa) |
| | NCU01247 | SCD domain-containing protein. (1226 aa) |
| | uvs-6 | UVS6. (1314 aa) |
| | mus-38 | MUS38. (960 aa) |
| | NCU04450 | Exonuclease V, mitochondrial; Single strand DNA specific 5' exonuclease involved in mitochondrial DNA replication and recombination. Releases dinucleotides as main products of catalysis. Has the capacity to slide across 5'double-stranded DNA or 5'RNA sequences and resumes cutting two nucleotides downstream of the double-stranded-to-single-stranded junction or RNA-to-DNA junction, respectively. (657 aa) |
| | NCU05006 | Cytochrome P450. (461 aa) |
| | NCU04548 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2259 aa) |
| | NCU03564 | Flap structure-specific endonuclease. (1037 aa) |
| | NCU00051 | Uncharacterized protein. (366 aa) |
| | NCU00081 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (695 aa) |
| | mus-52 | ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. ku70, of the ku70/ku80 heterodimer, binds to the stem loop of tlc1, the RNA component of telomerase. I [...] (725 aa) |
| | NCU00205 | Peptidase C50 domain-containing protein. (2185 aa) |
| | PIF1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (931 aa) |
| | NCU06481 | DNA ligase. (923 aa) |
| | NCU06457 | Asparaginyl-tRNA synthetase. (580 aa) |
| | NCU04378 | DNA replication initiation factor Cdc45. (874 aa) |
| | NCU03968 | SP-RING-type domain-containing protein. (404 aa) |
| | mus-21 | Serine/threonine-protein kinase tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability (By similarity). (2939 aa) |
| | NCU07554 | Structural maintenance of chromosomes protein. (1204 aa) |
| | NCU05972 | Sporulation-specific protein 6. (706 aa) |
| | NCU10044 | AP_endonuc_2 domain-containing protein. (516 aa) |
| | NCU07411 | DNA-directed DNA polymerase theta. (999 aa) |
| | NCU07410 | BTB domain-containing protein. (692 aa) |
| | msh1 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1249 aa) |
| | NCU10155 | DNA polymerase epsilon subunit B. (851 aa) |
| | NCU09503 | Uncharacterized protein. (1048 aa) |
| | NCU09500 | ATPase_AAA_core domain-containing protein. (1353 aa) |
| | NCU09297 | Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1249 aa) |
| | mus-41 | DNA repair protein rad5; Probable helicase, member of the UBC2/RAD6 epistasis group. Functions with DNA repair protein uvs-2/rad18 in error-free postreplication DNA repair. Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats. Seems to be involved in maintaining a balance which acts in favor of error-prone non-homologous joining during DNA double-strand breaks repairs (By similarity). (1228 aa) |
| | NCU09063 | Nuclear condensin complex subunit Smc4. (1650 aa) |
| | NCU05966 | DNA repair protein. (603 aa) |
| | NCU09439 | RecQ mediated genome instability protein Rmi1. (284 aa) |
| | NCU05984 | Formamidopyrimidine-DNA glycosylase. (415 aa) |
| | tof-1 | Topoisomerase 1-associated factor 1; Forms a fork protection complex (FPC) with csm-3 and which is required for chromosome segregation during meiosis and DNA damage repair. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity). (1235 aa) |
| | NCU09706 | DNA ligase. (917 aa) |
| | drc-3 | DNA replication complex GINS protein psf3; The GINS complex plays an essential role in the initiation of DNA replication. (218 aa) |
| | NCU06089 | Exonuclease. (758 aa) |
| | NCU02232 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (576 aa) |
| | msh6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1246 aa) |
| | NCU02402 | SMC_N domain-containing protein. (1167 aa) |
| | col-25 | Fungal specific transcription factor. (1194 aa) |
| | NCU06049 | DNA damage response protein RcaA. (912 aa) |
| | NCU09787 | Uncharacterized protein. (823 aa) |
| | mus-44 | Mating-type switching protein swi10. (405 aa) |
| | NCU04738 | Zf-primase domain-containing protein. (977 aa) |
| | mus-50 | UvrD/REP helicase. (1105 aa) |
| | NCU08879 | BRCT domain-containing protein. (1160 aa) |
| | NCU09681 | Uncharacterized protein. (589 aa) |
| | parp | Poly [ADP-ribose] polymerase. (670 aa) |
| | NCU06701 | Cephalosporin C regulator 1. (796 aa) |
| | NCU06572 | zf-C2HE domain-containing protein. (299 aa) |
| | NCU07891 | Endo/exonuclease/phosphatase domain-containing protein. (446 aa) |
| | NCU05250 | Sister chromatid cohesion protein. (1955 aa) |
| | rpa-2 | Replication protein A-2. (284 aa) |
| | NCU08806 | RECA_2 domain-containing protein. (442 aa) |
| | NCU05194 | DNA helicase; Belongs to the MCM family. (972 aa) |
| | NCU06547 | Uncharacterized protein. (624 aa) |
| | NCU07679 | Structural maintenance of chromosomes protein. (1179 aa) |
| | NCU06345 | Tyrosyl-DNA phosphodiesterase. (661 aa) |
| | NCU07313 | Chromosome transmission fidelity protein 18. (997 aa) |
| | NCU08317 | PHD-type domain-containing protein. (1021 aa) |
| | mus-51 | ATP-dependent DNA helicase II subunit 1; Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. ku70, of the ku70/ku80 heterodimer, binds to the stem loop of tlc1, the RNA component of telomerase. I [...] (645 aa) |
| | drc-2 | DNA replication complex GINS protein psf2; The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation (By similarity). (273 aa) |
| | NCU06992 | DNA repair protein Nse1. (342 aa) |
| | NCU06966 | Rhodanese domain-containing protein. (188 aa) |
| | pms-1 | DNA mismatch repair protein. (1157 aa) |
| | NCU08009 | DNA helicase; Belongs to the MCM family. (944 aa) |
| | NCU07998 | Uncharacterized protein. (441 aa) |
| | NCU07878 | RRM domain-containing protein. (356 aa) |
| | mus-53 | DNA ligase 4; Involved in ds DNA break repair. Has a role in non-homologous integration (NHI) pathways where it is required in the final step of non-homologous end-joining; Belongs to the ATP-dependent DNA ligase family. (1050 aa) |
| | NCU06269 | FHA domain-containing protein. (790 aa) |
| | NCU06216 | Nuclear condensin complex subunit 3. (1262 aa) |
| | csb | DNA repair protein Rhp26/Rad26. (1173 aa) |
| | stk-5 | Serine/threonine-protein kinase hal4; Belongs to the protein kinase superfamily. (497 aa) |
| | NCU06222 | Tyrosyl-DNA phosphodiesterase domain-containing protein. (691 aa) |
| | NCU07870 | DNA polymerase. (1479 aa) |
| | NCU06767 | Replication factor C subunit 1. (1086 aa) |
| | poli | DNA polymerase Tau. (660 aa) |
| | mus-43 | DNA repair protein rad14. (435 aa) |
| | mlh-2 | MUTL-2. (772 aa) |
| | NCU02828 | Condensin complex component cnd2. (904 aa) |
| | NCU09065 | SMC_N domain-containing protein. (1138 aa) |
| | NCU09384 | DNA_MISMATCH_REPAIR_2 domain-containing protein. (872 aa) |
| | mus-59 | Serine/threonine-protein kinase. (1233 aa) |
| | NCU03091 | Uncharacterized protein. (441 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (824 aa) |
| | msh-3 | DNA mismatch repair protein msh-3; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with msh-2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. Msh-3 provides substrate- binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch bi [...] (1145 aa) |
| | NCU07461 | DNA polymerase POL4. (846 aa) |
| | mus-81 | Crossover junction endonuclease mus-81; Interacts with eme-1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single- end invasion (SEI) (By similarity); Belongs to the XPF family. (645 aa) |
| | NCU02789 | Rif1_N domain-containing protein. (2032 aa) |
| | mus-42 | DNA repair protein REV1; Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template- dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesion. Required for normal induction of mutations by physical and chemical agents; Belongs to the DNA polymerase type-Y family. (1347 aa) |
| | mph1 | ATP-dependent DNA helicase mph1; ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork. Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily. (1168 aa) |
| | qde-3 | RecQ family helicase. (2330 aa) |
| | NCU03040 | N-glycosylase/DNA lyase. (449 aa) |
| | NCU03036 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (885 aa) |
| | drc-1 | DNA replication complex GINS protein psf1; The GINS complex plays an essential role in the initiation of DNA replication. (216 aa) |
| | polh | Sister chromatid cohesion protein Eso1. (672 aa) |
| | NCU03073 | CBFD_NFYB_HMF domain-containing protein. (397 aa) |
| | NCU03072 | SLD3 domain-containing protein. (1091 aa) |
| | NCU03291 | Double-strand-break repair protein rad21. (658 aa) |
| | ptk-2 | Serine/threonine protein kinase. (713 aa) |
| | NCU02187 | Uncharacterized protein. (291 aa) |
| | NCU02776 | Cell division control protein; Belongs to the CDC6/cdc18 family. (691 aa) |
| | NCU00517 | Cell cycle checkpoint protein RAD17. (944 aa) |
| | prd-4 | Serine/threonine-protein kinase chk2. (702 aa) |
| | NCU09261 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (221 aa) |
| | pcn | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa) |
| | NCU02001 | MAGE domain-containing protein. (334 aa) |
| | NCU00800 | Protein kinase domain-containing protein. (756 aa) |
| | NCU00798 | Uncharacterized protein. (312 aa) |
| | mus-40 | DNA excision repair protein Rad2. (1269 aa) |
| | UNG1 | Uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (449 aa) |
| | NCU03190 | Rec8. (763 aa) |
| | NCU02965 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (766 aa) |
| | NCU02687 | Activator 1 41 kDa subunit. (387 aa) |
| | NCU02683 | Uncharacterized protein. (738 aa) |
| | csm-3 | Chromosome segregation in meiosis protein 3; Forms a fork protection complex (FPC) with tof-1 and which is required for chromosome segregation during meiosis and DNA damage repair. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity). (409 aa) |
| | NCU02539 | DNA helicase; Belongs to the MCM family. (1013 aa) |
| | NCU00657 | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (431 aa) |
| | 5F3.150 | Probable DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. (513 aa) |
| | B14D6.460 | Replication factor C subunit 5; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. (352 aa) |
| | mus-23 | Double-strand break repair protein mus-23; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing (By similarity); Belongs to the MRE11/RAD32 family. (739 aa) |
| | mus-11 | DNA repair and recombination protein mus-11; Involved in DNA double-strand break (DSB) repair and recombination. Promotes the annealing of complementary single-stranded DNA and by stimulation of the mei-3/rad51 recombinase (By similarity). (600 aa) |
| | slx1 | Structure-specific endonuclease subunit slx1; Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (402 aa) |
| | mip-1 | DNA polymerase gamma, mitochondrial; Involved in the replication of mitochondrial DNA. (1456 aa) |
| | NCU00137 | SsDNA binding protein. (222 aa) |
| | NCU00470 | DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (484 aa) |
| | NCU00401 | Uncharacterized protein. (458 aa) |
| | NCU17268 | Uncharacterized protein. (286 aa) |
| | NCU04749 | DNA replication helicase Dna2. (1727 aa) |
| | NCU02457 | DNA-directed polymerase kappa, variant. (646 aa) |
| | NCU03820 | Checkpoint protein; Belongs to the HUS1 family. (371 aa) |
| | NCU10417 | BRCT domain-containing protein. (297 aa) |
| | NCU16767 | Uncharacterized protein. (182 aa) |
| | NCU06338 | DNA topoisomerase 2. (1994 aa) |
| | NCU01145 | Uncharacterized protein. (205 aa) |
| | NCU08700 | Uncharacterized protein. (1043 aa) |
| | mlh-1 | DNA mismatch repair protein mutL, variant. (751 aa) |
| | NCU01961 | DNA lyase Apn2. (655 aa) |
| | NCU03337 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (483 aa) |
| | NCU16387 | XPGI domain-containing protein. (226 aa) |
| | NCU09118 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (923 aa) |
| | NCU09240 | Vezatin domain-containing protein. (658 aa) |
| | NCU10376 | Uncharacterized protein. (441 aa) |
| | NCU16423 | Uncharacterized protein. (378 aa) |
| | NCU16422 | Uncharacterized protein. (79 aa) |
| | NCU10030 | Alpha-L-rhamnosidase C, variant. (822 aa) |
