Your Input: | |
| | Arg-4 | Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate. (469 aa) |
| | NCU11320 | Agmatinase; Belongs to the arginase family. (433 aa) |
| | NCU10220 | Adenylate kinase isoenzyme 6 homolog; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Has also ATPase activity. May be involved in rRNA maturation and transcription regulation. (175 aa) |
| | trp-2 | Anthranilate synthase component I. (582 aa) |
| | NCU08771 | Acetolactate synthase; Belongs to the TPP enzyme family. (608 aa) |
| | ad-7 | Amidophosphoribosyltransferase. (546 aa) |
| | NCU02979 | AMP deaminase. (1008 aa) |
| | NCU09930 | Folic acid synthesis protein. (548 aa) |
| | met-6 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (528 aa) |
| | trp-1 | Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. (762 aa) |
| | his-3 | Histidine biosynthesis trifunctional protein. (870 aa) |
| | trp-3 | Tryptophan synthase; In the C-terminal section; belongs to the TrpB family. (708 aa) |
| | arg-2 | Carbamoyl-phosphate synthase arginine-specific small chain, mitochondrial. (453 aa) |
| | spe-1 | Ornithine decarboxylase; Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis. (484 aa) |
| | aga-1 | Arginase; Belongs to the arginase family. (358 aa) |
| | leu-1 | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (368 aa) |
| | for | Serine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine. (480 aa) |
| | gch-1 | GTP cyclohydrolase 1; GTP cyclohydrolase 1 is the first enzyme in the biosynthetic pathway leading to folic acid. (313 aa) |
| | arg-6 | N-acetyl-gamma-glutamyl-phosphate reductase; In the N-terminal section; belongs to the acetylglutamate kinase family. (871 aa) |
| | aro-8 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family. (481 aa) |
| | aro-2 | Chorismate synthase; Bifunctional enzyme that possesses chorismate synthase and intrinsic flavin reductase activity, it uses NADPH to reduce FMN. (432 aa) |
| | B20D17.150 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (191 aa) |
| | NCU03425 | Threonine synthase. (553 aa) |
| | arg-12 | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (385 aa) |
| | ilv-4 | Acetolactate synthase small subunit. (330 aa) |
| | his-6 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (553 aa) |
| | NCU04579 | Dihydroxy-acid dehydratase. (596 aa) |
| | NCU07773 | Thymidylate kinase. (309 aa) |
| | NCU07771 | Uncharacterized protein. (427 aa) |
| | NCU04641 | FAD dependent oxidoreductase. (557 aa) |
| | NCU01246 | Urease accessory protein UreD. (330 aa) |
| | pro-3 | Gamma-glutamyl phosphate reductase. (445 aa) |
| | NCU06714 | Para-aminobenzoic acid synthetase. (963 aa) |
| | NCU04292 | Branched-chain-amino-acid aminotransferase. (414 aa) |
| | thr-4 | Homoserine kinase. (358 aa) |
| | NCU03761 | PALP domain-containing protein. (404 aa) |
| | NCU04118 | Aspartokinase. (522 aa) |
| | rad16 | DNA repair protein RAD16. (1079 aa) |
| | NCU03607 | Threonine dehydratase catabolic. (388 aa) |
| | NCU01348 | Agmatinase; Belongs to the arginase family. (392 aa) |
| | NCU01337 | Dihydrofolate synthetase; Belongs to the folylpolyglutamate synthase family. (412 aa) |
| | NCU01210 | Para-aminobenzoic acid synthetase. (795 aa) |
| | NCU06558 | D-amino-acid oxidase. (380 aa) |
| | arg-14 | Amino-acid acetyltransferase, mitochondrial; N-acetylglutamate synthase involved in arginine biosynthesis. (712 aa) |
| | NCU08434 | 5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase. (401 aa) |
| | ad-3A | Phosphoribosylaminoimidazole-succinocarboxamide synthase. (307 aa) |
| | dut-1 | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (165 aa) |
| | NCU01821 | Alanine-glyoxylate aminotransferase. (446 aa) |
| | NCU01439 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (466 aa) |
| | ser-7 | Phosphoserine aminotransferase. (429 aa) |
| | NCU05076 | Uncharacterized protein. (131 aa) |
| | NCU00177 | Phosphoribosylformylglycinamidine cyclo-ligase. (789 aa) |
| | his-7 | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (257 aa) |
| | NCU00438 | Adenosine deaminase. (346 aa) |
| | NCU03399 | Uncharacterized protein. (472 aa) |
| | pro-4 | Glutamate 5-kinase. (468 aa) |
| | NCU00414 | Adenosine kinase. (454 aa) |
| | trp-4 | Anthranilate phosphoribosyltransferase. (436 aa) |
| | leu-2 | 3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (779 aa) |
| | ala | Alanine aminotransferase. (566 aa) |
| | NCU03935 | Homoserine dehydrogenase. (365 aa) |
| | NCU04048 | A_deaminase domain-containing protein. (663 aa) |
| | pyr-7 | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. (579 aa) |
| | NCU10053 | Thymidylate synthase. (368 aa) |
| | NCU09911 | Formyltetrahydrofolate deformylase. (287 aa) |
| | NCU09545 | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (681 aa) |
| | NCU09703 | Acetolactate decarboxylase. (238 aa) |
| | NCU08151 | DNA kinase/phosphatase Pnk1. (524 aa) |
| | NCU02227 | Acetylornithine deacetylase. (452 aa) |
| | arg-10 | Argininosuccinate lyase. (466 aa) |
| | gua-3 | GMP synthase. (543 aa) |
| | NCU06117 | Uncharacterized protein. (595 aa) |
| | cbs-2 | Putative serine hydroxymethyltransferase, mitochondrial; Interconversion of serine and glycine. (546 aa) |
| | Ad-8 | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Belongs to the adenylosuccinate synthetase family. (430 aa) |
| | NCU04718 | DUF1752 domain-containing protein. (573 aa) |
| | NCU07115 | HET domain-containing protein. (622 aa) |
| | ilv-6 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (405 aa) |
| | aro-6 | Phospho-2-dehydro-3-deoxyheptonate aldolase. (379 aa) |
| | NCU04332 | Epoxide hydrolase. (360 aa) |
| | NCU08877 | Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (169 aa) |
| | NCU06673 | Deoxycytidylate deaminase. (395 aa) |
| | NCU07690 | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (613 aa) |
| | pyr-3 | PyrABCN. (1832 aa) |
| | NCU07725 | Chorismate mutase. (269 aa) |
| | NCU08685 | Phosphoribosylformylglycinamidine synthase. (1357 aa) |
| | NCU06360 | Histidinol-phosphate aminotransferase. (401 aa) |
| | NCU06349 | Uncharacterized protein. (255 aa) |
| | NCU06300 | Guanylate kinase. (215 aa) |
| | NCU06974 | Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (316 aa) |
| | NCU07590 | Ser/Thr protein phosphatase; Belongs to the 5'-nucleotidase family. (710 aa) |
| | ad-4 | Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (482 aa) |
| | NCU05683 | Dihydroxy-acid dehydratase. (640 aa) |
| | NCU02090 | Adenine phosphoribosyltransferase. (226 aa) |
| | aro-7 | Phospho-2-dehydro-3-deoxyheptonate aldolase. (376 aa) |
| | ad-9 | Phosphoribosylglycinamide formyltransferase. (231 aa) |
| | his-2 | ATP phosphoribosyltransferase. (337 aa) |
| | ad-5 | Bifunctional purine biosynthesis protein. (594 aa) |
| | NCU03076 | Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (601 aa) |
| | NCU02812 | Uridylate kinase; Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and dUMP as phosphate acceptors, but can also use CMP, dCMP and AMP. Belongs to the adenylate kinase family. UMP-CMP kinase subfamily. (343 aa) |
| | NCU02798 | FolB domain-containing protein. (331 aa) |
| | NCU02084 | Arginase; Belongs to the arginase family. (394 aa) |
| | hom-1 | Aspartate-semialdehyde dehydrogenase. (362 aa) |
| | NCU00893 | Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (610 aa) |
| | leu-4 | 2-isopropylmalate synthase. (625 aa) |
| | NCU02004 | Phosphoserine phosphatase. (496 aa) |
| | NCU00792 | Branched-chain-amino-acid aminotransferase. (413 aa) |
| | NCU03117 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (536 aa) |
| | NCU02475 | Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1100 aa) |
| | NCU02727 | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (477 aa) |
| | thr-5 | L-allo-threonine aldolase. (470 aa) |
| | NCU08094 | Dihydrofolate reductase. (398 aa) |
| | ADK2 | GTP:AMP phosphotransferase, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Has GTP:AMP phosphotransferase and ITP:AMP phosphotransferase activities. (273 aa) |
| | NCU03194 | Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (633 aa) |
| | arg-3 | Carbamoyl-phosphate synthase large subunit. (1168 aa) |
| | NCU02936 | Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (550 aa) |
| | aro-1 | 3-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family. (1563 aa) |
| | rnr-2 | Ribonucleoside-diphosphate reductase small chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (410 aa) |
| | adk-1 | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism. Adenylate kinase activity is critical for regulation of the phosphate utilization and the AMP de novo biosynthesis pathways. (278 aa) |
| | 65E11.030 | Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. (229 aa) |
| | arg-8 | Acetylornithine aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (461 aa) |
| | ndk-1 | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. (152 aa) |
| | rnr-1 | Ribonucleoside-diphosphate reductase large chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase large chain family. (929 aa) |
| | spe-3 | Spermidine synthase; Belongs to the spermidine/spermine synthase family. (291 aa) |
| | NCU00468 | Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family. (445 aa) |
| | NCU16651 | Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. (241 aa) |
| | ota | Ornithine aminotransferase. (452 aa) |
| | NCU00409 | Chorismate mutase/prephenate dehydratase, variant. (388 aa) |
| | NCU02450 | Threonine dehydratase. (584 aa) |
| | NCU12069 | Uncharacterized protein; Belongs to the adenylate kinase family. (459 aa) |
| | NCU03877 | C-1-tetrahydrofolate synthase. (1133 aa) |
| | NCU04771 | Fructosyl-amino acid oxidase, variant. (502 aa) |
| | NCU05500 | DAO domain-containing protein. (500 aa) |
| | NCU04642 | Adenosine deaminase, variant. (591 aa) |
| | NCU17227 | AB hydrolase-1 domain-containing protein. (427 aa) |
| | NCU17137 | Uncharacterized protein. (283 aa) |
| | NCU06320 | Uncharacterized protein. (687 aa) |
| | NCU07982 | Acetolactate synthase. (689 aa) |
| | arg-1 | Argininosuccinate synthase. (417 aa) |
| | NCU09116 | Aromatic aminotransferase Aro8, variant. (560 aa) |
| | NCU00963 | Methylenetetrahydrofolate dehydrogenase, variant. (342 aa) |
