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| | csm-3 | Chromosome segregation in meiosis protein 3; Forms a fork protection complex (FPC) with tof-1 and which is required for chromosome segregation during meiosis and DNA damage repair. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity). (409 aa) |
| | NCU02683 | Uncharacterized protein. (738 aa) |
| | NCU03190 | Rec8. (763 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (824 aa) |
| | NCU04738 | Zf-primase domain-containing protein. (977 aa) |
| | NCU05433 | Uncharacterized protein. (412 aa) |
| | mus-27 | Chromosome segregation protein. (879 aa) |
| | NCU01171 | DNA helicase; Belongs to the MCM family. (724 aa) |
| | pold-1 | DNA polymerase. (1104 aa) |
| | NCU06788 | Chromo domain-containing protein. (145 aa) |
| | NCU06395 | YL1_C domain-containing protein. (210 aa) |
| | NCU02232 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (576 aa) |
| | cac-2 | Chromatin assembly factor 1 protein. (732 aa) |
| | slx4 | Structure-specific endonuclease subunit slx4; Regulatory subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (1013 aa) |
| | NCU00897 | Sin3 complex subunit. (924 aa) |
| | NCU05194 | DNA helicase; Belongs to the MCM family. (972 aa) |
| | rpa-2 | Replication protein A-2. (284 aa) |
| | NCU07893 | RSC complex subunit Sfh1. (591 aa) |
| | mrc1 | MRC1. (1464 aa) |
| | NCU04327 | DNA helicase; Belongs to the MCM family. (882 aa) |
| | NCU06787 | MRG domain-containing protein. (366 aa) |
| | mei-3 | DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (353 aa) |
| | NCU03517 | Ski8. (342 aa) |
| | NCU00424 | Spo76 protein. (1595 aa) |
| | uvs-6 | UVS6. (1314 aa) |
| | NCU04548 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2259 aa) |
| | NCU03461 | Chromatin modification-related protein. (824 aa) |
| | ctc-1 | FACT complex subunit ctc-1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (565 aa) |
| | NCU00070 | PHD-type domain-containing protein. (888 aa) |
| | NCU00444 | Transcription initiation factor TFIID subunit 14. (226 aa) |
| | NCU00423 | PHD-type domain-containing protein. (1413 aa) |
| | snf5 | SWI-SNF complex subunit. (732 aa) |
| | crc-2 | SWR1-complex protein 5; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability (By similarity). (342 aa) |
| | NCU00118 | RRM domain-containing protein. (713 aa) |
| | set-4 | SET-4. (948 aa) |
| | NCU04378 | DNA replication initiation factor Cdc45. (874 aa) |
| | yaf9 | Protein AF-9 homolog; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised (By similarity). (309 aa) |
| | NCU07554 | Structural maintenance of chromosomes protein. (1204 aa) |
| | NCU07364 | Uncharacterized protein. (381 aa) |
| | NCU10155 | DNA polymerase epsilon subunit B. (851 aa) |
| | crf1-1 | Helicase swr-1; Catalytic component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling; Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily. (1845 aa) |
| | NCU07568 | HMG box domain-containing protein. (353 aa) |
| | NCU05979 | RXT2_N domain-containing protein. (580 aa) |
| | tof-1 | Topoisomerase 1-associated factor 1; Forms a fork protection complex (FPC) with csm-3 and which is required for chromosome segregation during meiosis and DNA damage repair. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity). (1235 aa) |
| | slx1 | Structure-specific endonuclease subunit slx1; Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (402 aa) |
| | NCU00470 | DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (484 aa) |
| | crf8-1 | TBP associated factor, variant. (1893 aa) |
| | NCU00401 | Uncharacterized protein. (458 aa) |
| | NCU07519 | ATP-dependent DNA helicase; Belongs to the helicase family. (813 aa) |
| | qde-2 | Post-transcriptional silencing protein QDE-2. (1089 aa) |
| | NCU04729 | NDT80 domain-containing protein. (726 aa) |
| | NCU03820 | Checkpoint protein; Belongs to the HUS1 family. (371 aa) |
| | NCU16971 | Uncharacterized protein. (236 aa) |
| | NCU10346 | Uncharacterized protein. (2592 aa) |
| | NCU08700 | Uncharacterized protein. (1043 aa) |
| | NCU01534 | PAPA-1 domain-containing protein. (430 aa) |
| | NCU10788 | Uncharacterized protein. (386 aa) |
| | fsd-1 | Female sexual development-1 protein. (626 aa) |
| | NCU02796 | Chromatin modification-related protein. (663 aa) |
| | NCU09240 | Vezatin domain-containing protein. (658 aa) |
| | NCU10376 | Uncharacterized protein. (441 aa) |
| | NCU16423 | Uncharacterized protein. (378 aa) |
| | NCU16422 | Uncharacterized protein. (79 aa) |
| | NCU02121 | Transcriptional regulator. (633 aa) |
| | NCU09813 | SMT3, variant 1. (99 aa) |
| | NCU07395 | DNA-binding protein SMUBP-2. (736 aa) |
| | spo11 | Meiosis-specific topoisomerase Spo11. (466 aa) |
| | NCU03763 | DNA polymerase delta subunit 2. (525 aa) |
| | rpa-1 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (610 aa) |
| | NCU03597 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (667 aa) |
| | NCU01370 | Uncharacterized protein. (603 aa) |
| | NCU01410 | DUF1711 domain-containing protein. (291 aa) |
| | NCU01362 | INO80 chromatin remodeling complex. (750 aa) |
| | sms-2 | Meiotic silencing suppressor 2; Belongs to the argonaute family. (989 aa) |
| | NCU01599 | Uncharacterized protein. (570 aa) |
| | hat-2 | Histone acetyltransferase type B subunit 2; Regulatory subunit of the histone acetylase B (HAT-B) complex. The complex acetylates 'Lys-12' of histone H4 which is required for telomeric silencing. (446 aa) |
| | drc-3 | DNA replication complex GINS protein psf3; The GINS complex plays an essential role in the initiation of DNA replication. (218 aa) |
| | arp-6 | Actin-related protein 6; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability (By similarity). (446 aa) |
| | pcn | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa) |
| | hda-3 | Histone deacetylase RPD3. (658 aa) |
| | NCU03291 | Double-strand-break repair protein rad21. (658 aa) |
| | NCU03073 | CBFD_NFYB_HMF domain-containing protein. (397 aa) |
| | polh | Sister chromatid cohesion protein Eso1. (672 aa) |
| | drc-1 | DNA replication complex GINS protein psf1; The GINS complex plays an essential role in the initiation of DNA replication. (216 aa) |
| | msh4 | MutS ortholog 4 protein. (1318 aa) |
| | vib-1 | Transcription factor vib-1; Transcription factor that acts as a positive regulator of nonrepressible acid phosphatase activity. Is a major regulator of responses to nitrogen and carbon starvation and is essential for the expression of genes involved in vegetative incompatibility (like pin-c, het-6, and tol). Vegetative incompatibility is a non-self-recognition system ubiquitous in filamentous fungi which results in programmed cell death. (670 aa) |
| | hh2a | Histone H2A; Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (134 aa) |
| | hel-1 | RuvB-like helicase 1; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (458 aa) |
| | 5F3.150 | Probable DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. (513 aa) |
| | hH2Az | Histone H2A.Z; Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activa [...] (143 aa) |
| | hel-2 | RuvB-like helicase 2; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (481 aa) |
| | crf2-1 | Chromatin-remodeling ATPase INO80; ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair. (1997 aa) |
| | crc-1 | SWR1-complex protein 4; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (733 aa) |
| | arp-5 | Chromatin remodeling complex subunit; Belongs to the actin family. (762 aa) |
| | NCU08317 | PHD-type domain-containing protein. (1021 aa) |
| | drc-2 | DNA replication complex GINS protein psf2; The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation (By similarity). (273 aa) |
| | NCU08039 | RING-type domain-containing protein. (359 aa) |
| | NCU08009 | DNA helicase; Belongs to the MCM family. (944 aa) |
| | NCU07998 | Uncharacterized protein. (441 aa) |
| | arp-8 | Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family. (748 aa) |
| | NCU07870 | DNA polymerase. (1479 aa) |
| | NCU02539 | DNA helicase; Belongs to the MCM family. (1013 aa) |
| | arp-4 | Actin-related protein 4; Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosome [...] (469 aa) |
