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NCU03291 | Double-strand-break repair protein rad21. (658 aa) | ||||
rpa-3 | Replication protein A-3. (108 aa) | ||||
msh4 | MutS ortholog 4 protein. (1318 aa) | ||||
cdc7 | Cell cycle protein kinase. (526 aa) | ||||
NCU01771 | DNA repair protein rhp57. (510 aa) | ||||
msh-2 | DNA mismatch repair protein msh-2; Involved in post-replicative DNA-mismatch repair. Binds to mismatch-containing DNA (By similarity). (937 aa) | ||||
mus-8 | Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation; Belongs to the ubiquitin-conjugating enzyme family. (151 aa) | ||||
NCU01569 | WD repeat containing protein 48. (1027 aa) | ||||
NCU04665 | Uncharacterized protein. (235 aa) | ||||
NCU01365 | ATP dependent DNA ligase domain-containing protein. (1072 aa) | ||||
NCU04327 | DNA helicase; Belongs to the MCM family. (882 aa) | ||||
spo11 | Meiosis-specific topoisomerase Spo11. (466 aa) | ||||
NCU03629 | Uncharacterized protein. (112 aa) | ||||
rpa-1 | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (610 aa) | ||||
NCU01340 | Uncharacterized protein. (215 aa) | ||||
NCU01171 | DNA helicase; Belongs to the MCM family. (724 aa) | ||||
gh61-4 | Endoglucanase II. (238 aa) | ||||
NCU05458 | Uncharacterized protein. (2319 aa) | ||||
upr-1 | DNA polymerase. (1938 aa) | ||||
mei-3 | DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (353 aa) | ||||
bI1 | Probable intron-encoded endonuclease bI1; Mitochondrial DNA endonuclease involved in intron homing. (448 aa) | ||||
NCU16009 | Probable intron-encoded endonuclease 2; Mitochondrial DNA endonuclease involved in intron homing. In the C-terminal section; belongs to the LAGLIDADG endonuclease family. (452 aa) | ||||
NCU16010 | Probable intron-encoded endonuclease 3; Mitochondrial DNA endonuclease involved in intron homing. In the C-terminal section; belongs to the LAGLIDADG endonuclease family. (533 aa) | ||||
NCU16011 | Probable intron-encoded endonuclease 4; Mitochondrial DNA endonuclease involved in intron homing. In the C-terminal section; belongs to the LAGLIDADG endonuclease family. (545 aa) | ||||
NCU16019 | Probable intron-encoded endonuclease 1; Mitochondrial DNA endonuclease involved in intron homing. (304 aa) | ||||
NCU03765 | 3'-5' exonuclease/helicase. (753 aa) | ||||
NCU03517 | Ski8. (342 aa) | ||||
mus-25 | DNA repair and recombination protein RAD54. (835 aa) | ||||
pp4 | Serine/threonine-protein phosphatase. (423 aa) | ||||
uvs-6 | UVS6. (1314 aa) | ||||
mus-38 | MUS38. (960 aa) | ||||
NCU03564 | Flap structure-specific endonuclease. (1037 aa) | ||||
NCU00081 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (695 aa) | ||||
mus-52 | ATP-dependent DNA helicase II subunit 2; Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. ku70, of the ku70/ku80 heterodimer, binds to the stem loop of tlc1, the RNA component of telomerase. I [...] (725 aa) | ||||
NCU03885 | Uncharacterized protein. (680 aa) | ||||
PIF1 | ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (931 aa) | ||||
NCU00030 | Endonuclease. (332 aa) | ||||
NCU04459 | Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation. (522 aa) | ||||
NCU06481 | DNA ligase. (923 aa) | ||||
NCU00103 | Uncharacterized protein. (292 aa) | ||||
NCU04378 | DNA replication initiation factor Cdc45. (874 aa) | ||||
NCU03968 | SP-RING-type domain-containing protein. (404 aa) | ||||
NCU06935 | Integrase_H2C2 domain-containing protein. (1347 aa) | ||||
NCU09855 | Nicotianamine synthase. (339 aa) | ||||
NCU09500 | ATPase_AAA_core domain-containing protein. (1353 aa) | ||||
NCU09439 | RecQ mediated genome instability protein Rmi1. (284 aa) | ||||
NCU09706 | DNA ligase. (917 aa) | ||||
nst-4 | Hst3p. (1327 aa) | ||||
drc-4 | DNA replication regulator sld2; Has a role in the initiation of DNA replication. Required at S-phase checkpoint (By similarity); Belongs to the SLD2 family. (610 aa) | ||||
gh61-1 | Endoglucanase II. (322 aa) | ||||
NCU06089 | Exonuclease. (758 aa) | ||||
NCU02402 | SMC_N domain-containing protein. (1167 aa) | ||||
NCU05756 | Peptidase M4. (449 aa) | ||||
NCU06049 | DNA damage response protein RcaA. (912 aa) | ||||
NCU09793 | DEAD/DEAH box DNA helicase. (1563 aa) | ||||
mus-44 | Mating-type switching protein swi10. (405 aa) | ||||
NCU05517 | Mitochondrial genome maintenance protein MGM101. (337 aa) | ||||
gpe-1 | tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] (354 aa) | ||||
NCU05250 | Sister chromatid cohesion protein. (1955 aa) | ||||
rpa-2 | Replication protein A-2. (284 aa) | ||||
NCU08806 | RECA_2 domain-containing protein. (442 aa) | ||||
NCU05194 | DNA helicase; Belongs to the MCM family. (972 aa) | ||||
sem-1 | Putative 26S proteasome complex subunit sem-1; Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis; Belongs to the DSS1/SEM1 family. (91 aa) | ||||
mus-51 | ATP-dependent DNA helicase II subunit 1; Single-stranded DNA-dependent ATP-dependent helicase. Involved in non-homologous end joining (NHEJ) DNA double strand break repair. DNA-binding is sequence-independent but has a high affinity to nicks in double-stranded DNA and to the ends of duplex DNA. Binds to naturally occurring chromosomal ends, and therefore provides chromosomal end protection. Required also for telomere recombination to repair telomeric ends in the absence of telomerase. ku70, of the ku70/ku80 heterodimer, binds to the stem loop of tlc1, the RNA component of telomerase. I [...] (645 aa) | ||||
drc-2 | DNA replication complex GINS protein psf2; The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation (By similarity). (273 aa) | ||||
crf5-1 | Chromatin remodeling factor 5-1. (907 aa) | ||||
NCU06992 | DNA repair protein Nse1. (342 aa) | ||||
NCU08039 | RING-type domain-containing protein. (359 aa) | ||||
NCU08009 | DNA helicase; Belongs to the MCM family. (944 aa) | ||||
NCU07998 | Uncharacterized protein. (441 aa) | ||||
mus-53 | DNA ligase 4; Involved in ds DNA break repair. Has a role in non-homologous integration (NHI) pathways where it is required in the final step of non-homologous end-joining; Belongs to the ATP-dependent DNA ligase family. (1050 aa) | ||||
nst-3 | SIR2 family histone deacetylase. (647 aa) | ||||
NCU09065 | SMC_N domain-containing protein. (1138 aa) | ||||
NCU09384 | DNA_MISMATCH_REPAIR_2 domain-containing protein. (872 aa) | ||||
MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (824 aa) | ||||
msh-3 | DNA mismatch repair protein msh-3; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with msh-2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. Msh-3 provides substrate- binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch bi [...] (1145 aa) | ||||
mus-81 | Crossover junction endonuclease mus-81; Interacts with eme-1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single- end invasion (SEI) (By similarity); Belongs to the XPF family. (645 aa) | ||||
mph1 | ATP-dependent DNA helicase mph1; ATP-dependent DNA helicase involved in DNA damage repair by homologous recombination and in genome maintenance. Capable of unwinding D-loops. Plays a role in limiting crossover recombinants during mitotic DNA double-strand break (DSB) repair. Component of a FANCM-MHF complex which promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork. Belongs to the DEAD box helicase family. DEAH subfamily. FANCM sub-subfamily. (1168 aa) | ||||
qde-3 | RecQ family helicase. (2330 aa) | ||||
NCU03036 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (885 aa) | ||||
drc-1 | DNA replication complex GINS protein psf1; The GINS complex plays an essential role in the initiation of DNA replication. (216 aa) | ||||
NCU07442 | Betaine aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (606 aa) | ||||
cdc5 | Serine/threonine protein kinase. (1021 aa) | ||||
slx4 | Structure-specific endonuclease subunit slx4; Regulatory subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (1013 aa) | ||||
NCU02001 | MAGE domain-containing protein. (334 aa) | ||||
cgi121 | EKC/KEOPS complex subunit cgi121; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Cgi121 acts as an allosteric effector that regulates the t(6)A activity of the complex. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. The complex is required for efficient recruitment of transc [...] (207 aa) | ||||
NCU02539 | DNA helicase; Belongs to the MCM family. (1013 aa) | ||||
NCU00657 | Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (431 aa) | ||||
mus-23 | Double-strand break repair protein mus-23; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing (By similarity); Belongs to the MRE11/RAD32 family. (739 aa) | ||||
mus-11 | DNA repair and recombination protein mus-11; Involved in DNA double-strand break (DSB) repair and recombination. Promotes the annealing of complementary single-stranded DNA and by stimulation of the mei-3/rad51 recombinase (By similarity). (600 aa) | ||||
slx1 | Structure-specific endonuclease subunit slx1; Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (402 aa) | ||||
NCU16705 | Chromo domain-containing protein. (145 aa) | ||||
NCU00401 | Uncharacterized protein. (458 aa) | ||||
NCU03820 | Checkpoint protein; Belongs to the HUS1 family. (371 aa) | ||||
NCU06338 | DNA topoisomerase 2. (1994 aa) | ||||
NCU16971 | Uncharacterized protein. (236 aa) | ||||
NCU05271 | Uncharacterized protein. (1316 aa) | ||||
NCU12100 | Uncharacterized protein. (84 aa) | ||||
mlh-1 | DNA mismatch repair protein mutL, variant. (751 aa) | ||||
NCU03337 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (483 aa) | ||||
NCU10788 | Uncharacterized protein. (386 aa) | ||||
NCU16423 | Uncharacterized protein. (378 aa) | ||||
NCU16422 | Uncharacterized protein. (79 aa) |