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NCU00780 NCU00780 pdx-1 pdx-1 NCU02450 NCU02450 cys-17 cys-17 NCU08216 NCU08216 cbs-2 cbs-2 ser-7 ser-7 NCU00536 NCU00536 cys-12 cys-12 NCU02004 NCU02004 NCU03607 NCU03607 NCU01071 NCU01071 NCU03788 NCU03788 NCU03761 NCU03761 for for
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
NCU00780D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (363 aa)
pdx-1Probable pyridoxal 5'-phosphate synthase subunit pdx-1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by pdx-2. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme- catalyzed isomerization of RBP and G3P, respectively. Also plays an indirect role in resistance to singlet oxygen-generating photosensitizers. (308 aa)
NCU02450Threonine dehydratase. (584 aa)
cys-17Cysteine synthase 1; Catalyzes the conversion of O-succinyl-L-serine into cysteine, the last step in the cysteine biosynthesis pathway. Can also use O-acetyl-L-serine; Belongs to the cysteine synthase/cystathionine beta- synthase family. (376 aa)
NCU08216Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (528 aa)
cbs-2Putative serine hydroxymethyltransferase, mitochondrial; Interconversion of serine and glycine. (546 aa)
ser-7Phosphoserine aminotransferase. (429 aa)
NCU00536Homoserine O-acetyltransferase. (525 aa)
cys-12Cysteine synthase 2; Putative cysteine synthase that catalyzes the conversion of O-acetyl-L-serine (OAS) into cysteine, the last step in the cysteine biosynthesis pathway. However, in contrast to cysteine synthase cys-17, this CS-like protein may not function in cysteine biosynthesis. (456 aa)
NCU02004Phosphoserine phosphatase. (496 aa)
NCU03607Threonine dehydratase catabolic. (388 aa)
NCU01071Uncharacterized protein. (388 aa)
NCU03788Cysteine synthase B. (525 aa)
NCU03761PALP domain-containing protein. (404 aa)
forSerine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine. (480 aa)
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A
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