STRINGSTRING
NCU05093 NCU05093 ser-7 ser-7 cys-17 cys-17 NCU04946 NCU04946 NCU06017 NCU06017 NCU03607 NCU03607 NCU01071 NCU01071 met-7 met-7 NCU01652 NCU01652 met-2 met-2 cys-16 cys-16 NCU01821 NCU01821 NCU06413 NCU06413 NCU00780 NCU00780 NCU02475 NCU02475 NCU02727 NCU02727 thr-5 thr-5 cys-12 cys-12 pdx-1 pdx-1 NCU16651 NCU16651 NCU02450 NCU02450 NCU16368 NCU16368 NCU00522 NCU00522 cbs-2 cbs-2 NCU08117 NCU08117 NCU00536 NCU00536 NCU02772 NCU02772 cys-11 cys-11 hom-1 hom-1 NCU02005 NCU02005 NCU02004 NCU02004 NCU09896 NCU09896 NCU03935 NCU03935 NCU03788 NCU03788 NCU03761 NCU03761 thr-4 thr-4 NCU04635 NCU04635 met-8 met-8 NCU07623 NCU07623 NCU06625 NCU06625 NCU08877 NCU08877 NCU08216 NCU08216 NCU04954 NCU04954 for for NCU04596 NCU04596
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCU05093Cystathionine gamma-synthase. (657 aa)
ser-7Phosphoserine aminotransferase. (429 aa)
cys-17Cysteine synthase 1; Catalyzes the conversion of O-succinyl-L-serine into cysteine, the last step in the cysteine biosynthesis pathway. Can also use O-acetyl-L-serine; Belongs to the cysteine synthase/cystathionine beta- synthase family. (376 aa)
NCU04946DUF5353 domain-containing protein. (184 aa)
NCU06017Thiosulfate sulfurtransferase. (333 aa)
NCU03607Threonine dehydratase catabolic. (388 aa)
NCU01071Uncharacterized protein. (388 aa)
met-7Cystathionine gamma-synthase; Catalyzes the formation of L-cystathionine from O-succinyl-L- homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction. In the absence of thiol, catalyzes gamma-elimination to form 2- oxobutanoate, succinate and ammonia (By similarity). (621 aa)
NCU01652O-acetylhomoserine. (454 aa)
met-2Cystathionine beta-lyase; Involved in de novo synthesis of methionine. Belongs to the trans-sulfuration enzymes family. (457 aa)
cys-16Cystathionine gamma-lyase. (417 aa)
NCU01821Alanine-glyoxylate aminotransferase. (446 aa)
NCU06413Uncharacterized protein. (761 aa)
NCU00780D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (363 aa)
NCU02475Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1100 aa)
NCU02727Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (477 aa)
thr-5L-allo-threonine aldolase. (470 aa)
cys-12Cysteine synthase 2; Putative cysteine synthase that catalyzes the conversion of O-acetyl-L-serine (OAS) into cysteine, the last step in the cysteine biosynthesis pathway. However, in contrast to cysteine synthase cys-17, this CS-like protein may not function in cysteine biosynthesis. (456 aa)
pdx-1Probable pyridoxal 5'-phosphate synthase subunit pdx-1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by pdx-2. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme- catalyzed isomerization of RBP and G3P, respectively. Also plays an indirect role in resistance to singlet oxygen-generating photosensitizers. (308 aa)
NCU16651Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. (241 aa)
NCU02450Threonine dehydratase. (584 aa)
NCU16368D-ser_dehydrat domain-containing protein. (494 aa)
NCU00522Cystathionine beta-lyase. (419 aa)
cbs-2Putative serine hydroxymethyltransferase, mitochondrial; Interconversion of serine and glycine. (546 aa)
NCU08117Uncharacterized protein. (675 aa)
NCU00536Homoserine O-acetyltransferase. (525 aa)
NCU02772FR47 domain-containing protein. (476 aa)
cys-11Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the C-terminal section; belongs to the APS kinase family. (573 aa)
hom-1Aspartate-semialdehyde dehydrogenase. (362 aa)
NCU02005Phosphoadenosine phosphosulfate reductase. (398 aa)
NCU02004Phosphoserine phosphatase. (496 aa)
NCU09896Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (211 aa)
NCU03935Homoserine dehydrogenase. (365 aa)
NCU03788Cysteine synthase B. (525 aa)
NCU03761PALP domain-containing protein. (404 aa)
thr-4Homoserine kinase. (358 aa)
NCU04635Uncharacterized protein. (182 aa)
met-8Methionine synthase. (769 aa)
NCU076232,2-dialkylglycine decarboxylase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (535 aa)
NCU06625Cysteine dioxygenase. (235 aa)
NCU08877Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (169 aa)
NCU08216Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (528 aa)
NCU04954Myb_DNA-bind_3 domain-containing protein. (424 aa)
forSerine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine. (480 aa)
NCU04596Gamma-cysteine synthetase regulatory subunit. (333 aa)
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A
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