STRINGSTRING
cys-12 cys-12 NCU01821 NCU01821 ser-7 ser-7 cys-17 cys-17 NCU03935 NCU03935 NCU09896 NCU09896 NCU08216 NCU08216 cbs-2 cbs-2 NCU07623 NCU07623 NCU00536 NCU00536 cys-11 cys-11 hom-1 hom-1 NCU02005 NCU02005 NCU00780 NCU00780 thr-5 thr-5 pdx-1 pdx-1 NCU16651 NCU16651 NCU02004 NCU02004 met-2 met-2 NCU03607 NCU03607 NCU03788 NCU03788 for for
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cys-12Cysteine synthase 2; Putative cysteine synthase that catalyzes the conversion of O-acetyl-L-serine (OAS) into cysteine, the last step in the cysteine biosynthesis pathway. However, in contrast to cysteine synthase cys-17, this CS-like protein may not function in cysteine biosynthesis. (456 aa)
NCU01821Alanine-glyoxylate aminotransferase. (446 aa)
ser-7Phosphoserine aminotransferase. (429 aa)
cys-17Cysteine synthase 1; Catalyzes the conversion of O-succinyl-L-serine into cysteine, the last step in the cysteine biosynthesis pathway. Can also use O-acetyl-L-serine; Belongs to the cysteine synthase/cystathionine beta- synthase family. (376 aa)
NCU03935Homoserine dehydrogenase. (365 aa)
NCU09896Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (211 aa)
NCU08216Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (528 aa)
cbs-2Putative serine hydroxymethyltransferase, mitochondrial; Interconversion of serine and glycine. (546 aa)
NCU076232,2-dialkylglycine decarboxylase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (535 aa)
NCU00536Homoserine O-acetyltransferase. (525 aa)
cys-11Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the C-terminal section; belongs to the APS kinase family. (573 aa)
hom-1Aspartate-semialdehyde dehydrogenase. (362 aa)
NCU02005Phosphoadenosine phosphosulfate reductase. (398 aa)
NCU00780D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (363 aa)
thr-5L-allo-threonine aldolase. (470 aa)
pdx-1Probable pyridoxal 5'-phosphate synthase subunit pdx-1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by pdx-2. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme- catalyzed isomerization of RBP and G3P, respectively. Also plays an indirect role in resistance to singlet oxygen-generating photosensitizers. (308 aa)
NCU16651Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. (241 aa)
NCU02004Phosphoserine phosphatase. (496 aa)
met-2Cystathionine beta-lyase; Involved in de novo synthesis of methionine. Belongs to the trans-sulfuration enzymes family. (457 aa)
NCU03607Threonine dehydratase catabolic. (388 aa)
NCU03788Cysteine synthase B. (525 aa)
forSerine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine. (480 aa)
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A
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