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| | mus-8 | Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation; Belongs to the ubiquitin-conjugating enzyme family. (151 aa) |
| | hsp98 | Heat shock protein hsp98; Required, in concert with Hsp40 and Hsp70 and small Hsps, for the dissociation, resolubilization and refolding of aggregates of damaged proteins after heat or other environmental stresses. Extracts proteins from aggregates by unfolding and threading them in an ATP- dependent process through the axial channel of the protein hexamer, after which they can be refolded by components of the Hsp70/Hsp40 chaperone system (By similarity). (927 aa) |
| | nmr | Nitrogen metabolite repression protein nmr; May be a redox sensor protein. Negative transcriptional regulator involved in the post-transcriptional modulation of the GATA- type transcription factor nit-2, forming part of a system controlling nitrogen metabolite repression (By similarity). (488 aa) |
| | hsp30 | 30 kDa heat shock protein; Belongs to the small heat shock protein (HSP20) family. (228 aa) |
| | cpc-1 | Cross-pathway control protein 1; In N.crassa grown under amino acid starvation conditions, this protein is required for increasing the transcription of the genes coding for many amino acid biosynthetic pathways enzymes. This transcription factor binds and recognize the DNA sequence: 5'-TGACTC- 3'. (270 aa) |
| | gnb-1 | Guanine nucleotide-binding protein beta subunit. (358 aa) |
| | NCU09623 | Uncharacterized protein. (222 aa) |
| | NCU04577 | Uncharacterized protein. (443 aa) |
| | NCU11102 | SCJ1. (426 aa) |
| | NCU11109 | ORM1. (180 aa) |
| | NCU10270 | Uncharacterized protein. (290 aa) |
| | NCU10273 | Hsc70 cochaperone. (365 aa) |
| | NCU11215 | RING-10 protein. (851 aa) |
| | gh47-4 | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (612 aa) |
| | NCU00515 | RING-type domain-containing protein. (935 aa) |
| | NCU16447 | Uncharacterized protein. (136 aa) |
| | NCU11372 | NOT2_3_5 domain-containing protein. (485 aa) |
| | NCU01296 | Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (261 aa) |
| | NCU03357 | Ubiquitin conjugation factor E4. (1102 aa) |
| | gh47-6 | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (956 aa) |
| | NCU03742 | PfkB domain-containing protein. (437 aa) |
| | NCU02353 | OTU domain-containing protein. (316 aa) |
| | mek-2 | Mitogen activated protein kinase kinase 2. (511 aa) |
| | NCU10572 | Short chain oxidoreductase, variant. (177 aa) |
| | NCU06150 | J domain-containing protein. (332 aa) |
| | NCU05994 | Transcription factor TamA. (801 aa) |
| | mak-2 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (352 aa) |
| | NCU00376 | GTR/RAG family GTPase Gtr2. (427 aa) |
| | NCU00018 | Cell division control protein Cdc48, variant; Belongs to the AAA ATPase family. (824 aa) |
| | cdc42 | Rho-type GTPase. (196 aa) |
| | fes-1-2 | Hsp70 nucleotide exchange factor fes-1; Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP. Required for fully efficient Hsp70-mediated folding of proteins (By similarity). Belongs to the FES1 family. (246 aa) |
| | sts1 | Tethering factor for nuclear proteasome sts1; Involved in ubiquitin-mediated protein degradation. Regulatory factor in the ubiquitin/proteasome pathway that controls the turnover of proteasome substrates. Targets proteasomes to the nucleus and facilitates the degradation of nuclear proteins (By similarity). (304 aa) |
| | bli-4 | Putative oxidoreductase bli-4, mitochondrial; May play a role as an NAD-dependent dehydrogenase in the mitochondria. (412 aa) |
| | lcl2 | Long chronological lifespan protein 2; Probable component of the endoplasmic reticulum-associated degradation (ERAD) pathway. (132 aa) |
| | gtr-1 | Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. (468 aa) |
| | yos-9 | Protein OS-9 homolog; Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation (By similarity). (590 aa) |
| | sec-61 | Protein transport protein SEC61 subunit alpha; Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secretory proteins and is essential for cell growth. It interacts with other membrane proteins required for protein translocation. Upon binding to SEC62/63 complex, secretory precursor polypeptides may engage SEC61 to begin membrane penetration event. A cycle of assembly and disassembly of SEC62/63 from SEC61 may govern the activity of the translocase (By similarity). (476 aa) |
| | get3 | ATPase get3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (339 aa) |
| | NCU00621 | TORC1 growth control complex subunit Kog1. (1473 aa) |
| | NCU10789 | Ubiquitin-protein ligase Sel1/Ubx2. (859 aa) |
| | NCU01856 | Transcriptional activator hac1. (580 aa) |
| | npl4 | Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family. (660 aa) |
| | NCU02463 | Bax Inhibitor family protein; Belongs to the BI1 family. (287 aa) |
| | NCU00770 | Uncharacterized protein. (1845 aa) |
| | NCU02147 | Ankyrin repeat and zinc finger domain-containing protein 1. (649 aa) |
| | NCU02153 | UBX domain-containing protein. (554 aa) |
| | NCU03303 | TUG-UBL1 domain-containing protein. (530 aa) |
| | NCU09735 | Short-chain dehydrogenase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (327 aa) |
| | gh47-1 | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (804 aa) |
| | gh47-2 | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (657 aa) |
| | NCU01928 | UBX domain-containing protein. (514 aa) |
| | ham-4 | FHA domain-containing protein. (797 aa) |
| | NCU09378 | DNA-directed RNA polymerase II polypeptide. (146 aa) |
| | NCU00802 | Uncharacterized protein. (540 aa) |
| | gh47-7 | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (1172 aa) |
| | NCU08736 | Cytidylyltransferase. (408 aa) |
| | NCU09479 | Uncharacterized protein. (263 aa) |
| | NCU09485 | Chaperone dnaK. (1005 aa) |
| | NCU08555 | Uncharacterized protein. (530 aa) |
| | NCU08008 | Adenylyl cyclase-associated protein; Belongs to the CAP family. (522 aa) |
| | NCU06980 | Uncharacterized protein. (1261 aa) |
| | NCU07333 | AAA domain-containing protein. (671 aa) |
| | iml2 | Inclusion body clearance protein iml2; Inclusion body (IB) resident protein that interacts strongly with lipid droplet (LD) proteins. Involved in LD-mediated IB clearing after protein folding stress, probably by enabling access to the IBs of an LD-stored soluble sterol derivative that acts as chaperone in inclusion clearing. (811 aa) |
| | NCU07672 | CUE domain-containing protein. (222 aa) |
| | nma111 | Pro-apoptotic serine protease nma111; Nuclear serine protease which mediates apoptosis. Belongs to the peptidase S1C family. (1026 aa) |
| | NCU06576 | Uncharacterized protein. (409 aa) |
| | NCU05160 | ATP-dependent Zn protease. (486 aa) |
| | NCU05259 | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (477 aa) |
| | NCU06281 | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1486 aa) |
| | NCU03592 | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1743 aa) |
| | NCU03613 | Opy2 domain-containing protein. (425 aa) |
| | NCU04267 | Uncharacterized protein. (605 aa) |
| | NCU01268 | Ubiquitin-conjugating enzyme E2 6. (317 aa) |
| | NCU01276 | N-acetyltransferase 5. (190 aa) |
| | NCU05582 | Ubiquitin fusion degradation protein. (784 aa) |
| | NCU05592 | Ubiquitin-conjugating enzyme. (264 aa) |
| | NCU04800 | E3 ubiquitin-protein ligase. (1145 aa) |
| | NCU04725 | N-acetylglucosamine-6-phosphate deacetylase. (540 aa) |
| | gh47-5 | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (710 aa) |
| | NCU04778 | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (230 aa) |
| | NCU07061 | Uncharacterized protein. (177 aa) |
| | NCU09579 | Retinol dehydrogenase 12. (353 aa) |
| | NCU08133 | Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family. (283 aa) |
| | NCU08164 | Retinol dehydrogenase 13. (351 aa) |
| | NCU02424 | DnaJ and TPR domain-containing protein. (517 aa) |
| | NCU06091 | Vacuolar protein sorting-associated protein 74. (349 aa) |
| | stk-14 | Serine/threonine kinase IREI. (1208 aa) |
| | NCU02243 | Uncharacterized protein. (551 aa) |
| | NCU09565 | Uncharacterized protein; Belongs to the cytochrome P450 family. (554 aa) |
| | NCU02349 | UDP-glucose:glycoprotein glucosyltransferase. (1500 aa) |
| | NCU09176 | Uncharacterized protein. (375 aa) |
| | rad23 | Rad23-like protein. (383 aa) |
| | gh47-8 | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (602 aa) |
| | rpt-4 | Proteasome 26S subunit; Belongs to the AAA ATPase family. (390 aa) |
| | NCU09540 | Methyltranfer_dom domain-containing protein. (601 aa) |
| | NCU09541 | ACT_7 domain-containing protein. (437 aa) |
| | NCU07565 | Von Willebrand RING finger domain-containing protein. (1161 aa) |
| | NCU09278 | Oxidoreductase. (314 aa) |
| | NCU09305 | Abhydrolase_3 domain-containing protein. (343 aa) |
| | NCU07516 | RING finger membrane protein. (1793 aa) |
| | NCU09420 | Hsp20-like protein; Belongs to the small heat shock protein (HSP20) family. (215 aa) |
| | NCU09015 | Uncharacterized protein. (875 aa) |
| | NCU00275 | RING-type domain-containing protein. (428 aa) |
| | NCU00352 | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1360 aa) |
| | nup-20 | Protein transport protein sec13; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport facto [...] (304 aa) |
| | stk-4 | Serine/threonine-protein kinase ste20; MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle. Phosphorylates histone H2B to form H2BS10ph (By similarity). Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (954 aa) |
| | vel | Non-specific serine/threonine protein kinase. (833 aa) |
| | pbn1 | Protein pbn1; Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase gim- 1/gpi14 (By similarity). (501 aa) |
| | NCU06479 | Uncharacterized protein. (363 aa) |
| | NCU01699 | Uncharacterized protein. (389 aa) |
| | ty-1 | Mapkkk cascade protein kinase regulator ste50. (480 aa) |
| | NCU00434 | Protein phosphatase 2C isoform beta. (619 aa) |
| | NCU00146 | Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (250 aa) |
| | NCU00173 | S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (368 aa) |
| | NCU03373 | Uncharacterized protein. (113 aa) |
| | gng-1 | Guanine nucleotide-binding protein subunit gamma; Belongs to the G protein gamma family. (93 aa) |
| | NCU07232 | Heat shock protein 30; Belongs to the small heat shock protein (HSP20) family. (279 aa) |
| | nrc-1 | MAPKK kinase. (914 aa) |
| | hsp70-5 | Hsp70-like protein; Belongs to the heat shock protein 70 family. (668 aa) |
| | NCU03637 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (462 aa) |
| | dim-2 | DNA methyltransferase Dim-2. (1454 aa) |
| | NCU02968 | TMF_TATA_bd domain-containing protein. (900 aa) |
| | os-1 | Histidine kinase. (1298 aa) |
| | NCU06856 | Ubiquitin fusion degradation protein. (382 aa) |
| | gh47-3 | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (610 aa) |
| | NCU01099 | GTP-binding protein GTR1. (409 aa) |
| | NCU01107 | Short-chain dehydrogenase. (333 aa) |
| | cpc-3 | Cpc-3 protein. (1646 aa) |
| | NCU01220 | BAG domain-containing protein. (357 aa) |
| | NCU01225 | Ubiquitin conjugating enzyme; Belongs to the ubiquitin-conjugating enzyme family. (235 aa) |
| | NCU03704 | Ubiquitin carboxyl-terminal hydrolase. (331 aa) |
| | NCU03623 | Ubiquitin-conjugating enzyme E; Belongs to the ubiquitin-conjugating enzyme family. (166 aa) |
| | NCU04139 | Flavin_Reduct domain-containing protein. (357 aa) |
| | hsp80 | Heat shock protein 80. (705 aa) |
| | NCU06711 | Uncharacterized protein. (245 aa) |
| | NCU01356 | Uncharacterized protein. (541 aa) |
| | pre-2 | Pheromone receptor. (566 aa) |
| | NCU04633 | RING finger protein. (829 aa) |
| | NCU04635 | Uncharacterized protein. (182 aa) |
| | NCU03903 | Lipase/esterase. (496 aa) |
| | NCU05128 | Uncharacterized protein; Belongs to the cytochrome P450 family. (553 aa) |
| | NCU03335 | ER associated DnaJ chaperone. (359 aa) |
| | gna-1 | Guanine nucleotide-binding protein alpha-1 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems; Belongs to the G-alpha family. G(q) subfamily. (353 aa) |
| | gna-2 | Guanine nucleotide-binding protein alpha-2 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems; Belongs to the G-alpha family. G(q) subfamily. (355 aa) |
| | ccg-8 | Clock-controlled protein 8. (661 aa) |
| | ccg-4 | Clock-controlled pheromone ccg-4; Pheromone that is regulated by the circadian clock. Expression is mating type specific and under the control of the mating type locus. Involved in conidiation. (299 aa) |
| | hsps-1 | Heat shock 70 kDa protein. (646 aa) |
| | cnb-1 | Calcineurin subunit B; Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. (174 aa) |
| | grp78 | Endoplasmic reticulum chaperone BiP; Probably plays a role in facilitating the assembly of multimeric protein complexes inside the ER. Is required for secretory polypeptide translocation. May physically associate with SEC63 protein in the endoplasmic reticulum and this interaction may be regulated by ATP hydrolysis; Belongs to the heat shock protein 70 family. (661 aa) |
