STRINGSTRING
NCU00800 NCU00800 NCU16448 NCU16448 NCU10043 NCU10043 NCU08599 NCU08599 NCU16422 NCU16422 NCU01584 NCU01584 NCU16423 NCU16423 NCU08345 NCU08345 os-5 os-5 rgf3 rgf3 camk-4 camk-4 un-1 un-1 rgb-1 rgb-1 stk-46 stk-46 rho-4 rho-4 NCU06389 NCU06389 NCU03545 NCU03545 NCU01278 NCU01278 NCU09860 NCU09860 NCU03820 NCU03820 NCU03768 NCU03768 ham-2 ham-2 NCU00470 NCU00470 cdc42 cdc42 pph-3 pph-3 mob1-1 mob1-1 mus-23 mus-23 NCU02932 NCU02932 csm-3 csm-3 NCU03237 NCU03237 NCU00978 NCU00978 NCU02496 NCU02496 NCU02616 NCU02616 NCU03103 NCU03103 cdc5 cdc5 NCU03178 NCU03178 prd-4 prd-4 NCU09744 NCU09744 eat-6 eat-6 NCU00512 NCU00512 NCU00517 NCU00517 NCU02776 NCU02776 NCU02114 NCU02114 NCU09812 NCU09812 NCU02058 NCU02058 mus-81 mus-81 mus-59 mus-59 NCU09382 NCU09382 NCU03246 NCU03246 dot-1 dot-1 NCU06269 NCU06269 NCU06980 NCU06980 NCU07679 NCU07679 NCU05282 NCU05282 NCU01174 NCU01174 NCU03786 NCU03786 NCU01269 NCU01269 NCU08878 NCU08878 NCU08879 NCU08879 NCU05781 NCU05781 NCU06144 NCU06144 NCU06145 NCU06145 NCU06049 NCU06049 cdc24 cdc24 NCU02357 NCU02357 NCU02358 NCU02358 NCU05901 NCU05901 NCU08216 NCU08216 NCU05945 NCU05945 tof-1 tof-1 NCU09302 NCU09302 NCU09503 NCU09503 NCU09015 NCU09015 NCU05972 NCU05972 mus-21 mus-21 NCU00325 NCU00325 stk-4 stk-4 NCU03944 NCU03944 NCU04384 NCU04384 NCU04386 NCU04386 NCU04428 NCU04428 stk-42 stk-42 NCU06437 NCU06437 vel vel stk-13 stk-13 NCU00118 NCU00118 stk-43 stk-43 NCU00213 NCU00213 NCU03351 NCU03351 NCU01572 NCU01572 NCU00494 NCU00494 NCU03564 NCU03564 NCU03860 NCU03860 pp4 pp4 camk-2 camk-2 mdk-1 mdk-1 mak-1 mak-1 cdc28 cdc28 sad-1 sad-1 rrp3 rrp3 NCU01182 NCU01182 cpc-3 cpc-3 mrc1 mrc1 stk-29 stk-29 NCU01377 NCU01377 NCU06710 NCU06710 tng tng mus-8 mus-8 NCU04577 NCU04577 cdc7 cdc7 NCU11300 NCU11300 NCU00488 NCU00488
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCU00800Protein kinase domain-containing protein. (756 aa)
NCU16448PARP-type domain-containing protein. (403 aa)
NCU10043Mitotic spindle checkpoint component mad3. (1292 aa)
NCU08599Uncharacterized protein. (620 aa)
NCU16422Uncharacterized protein. (79 aa)
NCU01584Uncharacterized protein. (1012 aa)
NCU16423Uncharacterized protein. (378 aa)
NCU08345Ubiquitin-conjugating enzyme E; Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
os-5Mitogen activated protein kinase kinase, variant. (683 aa)
rgf3Rho guanyl nucleotide exchange factor. (1744 aa)
camk-4Serine/threonine-protein kinase. (630 aa)
un-1Serine/threonine protein kinase. (620 aa)
rgb-1Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (481 aa)
stk-46Serine/threonine protein kinase. (1405 aa)
rho-4Rho1. (337 aa)
NCU06389DUF625 domain-containing protein, variant. (976 aa)
NCU03545Uncharacterized protein. (2101 aa)
NCU01278Uncharacterized protein. (862 aa)
NCU09860Telomere silencing protein Zds1, variant. (870 aa)
NCU03820Checkpoint protein; Belongs to the HUS1 family. (371 aa)
NCU03768Lysophospholipase, variant 1. (595 aa)
ham-2Hyphal anastamosis protein 2. (1105 aa)
NCU00470DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (484 aa)
cdc42Rho-type GTPase. (196 aa)
pph-3Serine/threonine-protein phosphatase PP1; Belongs to the PPP phosphatase family. PP-1 subfamily. (308 aa)
mob1-1Probable maintenance of ploidy protein mob1; Belongs to the MOB1/phocein family. (219 aa)
mus-23Double-strand break repair protein mus-23; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing (By similarity); Belongs to the MRE11/RAD32 family. (739 aa)
NCU02932mRNA stability protein; Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway. (199 aa)
csm-3Chromosome segregation in meiosis protein 3; Forms a fork protection complex (FPC) with tof-1 and which is required for chromosome segregation during meiosis and DNA damage repair. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity). (409 aa)
NCU03237Mitotic check point protein. (536 aa)
NCU00978Checkpoint protein kinase. (921 aa)
NCU02496M-phase inducer phosphatase 3. (554 aa)
NCU02616WD-repeat containing protein slp1. (609 aa)
NCU03103Spc7 domain-containing protein. (1483 aa)
cdc5Serine/threonine protein kinase. (1021 aa)
NCU03178PHD-type domain-containing protein. (580 aa)
prd-4Serine/threonine-protein kinase chk2. (702 aa)
NCU09744Nuclear pore complex subunit. (353 aa)
eat-6Anaphase-promoting complex subunit Apc5. (813 aa)
NCU00512CULLIN_2 domain-containing protein; Belongs to the cullin family. (1103 aa)
NCU00517Cell cycle checkpoint protein RAD17. (944 aa)
NCU02776Cell division control protein; Belongs to the CDC6/cdc18 family. (691 aa)
NCU02114G1/S-specific cyclin Cln1; Belongs to the cyclin family. (416 aa)
NCU09812LIM domain-containing protein. (944 aa)
NCU02058Uncharacterized protein. (579 aa)
mus-81Crossover junction endonuclease mus-81; Interacts with eme-1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single- end invasion (SEI) (By similarity); Belongs to the XPF family. (645 aa)
mus-59Serine/threonine-protein kinase. (1233 aa)
NCU09382TPR domain-containing protein. (386 aa)
NCU03246Tyrosine-protein phosphatase CDC14. (654 aa)
dot-1Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically trimethylates histone H3 to form H3K79me3. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histone. (531 aa)
NCU06269FHA domain-containing protein. (790 aa)
NCU06980Uncharacterized protein. (1261 aa)
NCU07679Structural maintenance of chromosomes protein. (1179 aa)
NCU05282Spindle pole body component. (1042 aa)
NCU01174Anaphase-promoting complex subunit CDC23. (673 aa)
NCU03786Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (670 aa)
NCU01269Cell cycle regulatory protein. (611 aa)
NCU08878TEM1. (314 aa)
NCU08879BRCT domain-containing protein. (1160 aa)
NCU05781Mitotic spindle checkpoint component MAD2. (244 aa)
NCU06144Kinesin; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1289 aa)
NCU06145RING-6. (367 aa)
NCU06049DNA damage response protein RcaA. (912 aa)
cdc24Rho guanyl nucleotide exchange factor. (997 aa)
NCU02357Importin subunit beta-3. (1096 aa)
NCU02358SDS23; Involved in DNA replication and cell separation. Belongs to the SDS23 family. (542 aa)
NCU05901Uncharacterized protein. (2077 aa)
NCU08216Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (528 aa)
NCU05945Uncharacterized protein. (408 aa)
tof-1Topoisomerase 1-associated factor 1; Forms a fork protection complex (FPC) with csm-3 and which is required for chromosome segregation during meiosis and DNA damage repair. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity). (1235 aa)
NCU09302DNA damage-binding protein cmr1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes. (521 aa)
NCU09503Uncharacterized protein. (1048 aa)
NCU09015Uncharacterized protein. (875 aa)
NCU05972Sporulation-specific protein 6. (706 aa)
mus-21Serine/threonine-protein kinase tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability (By similarity). (2939 aa)
NCU00325Uncharacterized protein. (435 aa)
stk-4Serine/threonine-protein kinase ste20; MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle. Phosphorylates histone H2B to form H2BS10ph (By similarity). Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (954 aa)
NCU03944WD repeat containing protein 2. (618 aa)
NCU04384Uncharacterized protein. (1034 aa)
NCU04386Uncharacterized protein. (521 aa)
NCU04428Uncharacterized protein. (825 aa)
stk-42Serine/threonine protein kinase-42. (562 aa)
NCU06437RING-type domain-containing protein. (1128 aa)
velNon-specific serine/threonine protein kinase. (833 aa)
stk-13Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (420 aa)
NCU00118RRM domain-containing protein. (713 aa)
stk-43Serine/threonine protein kinase-43. (682 aa)
NCU00213Nuclear protein bimA. (820 aa)
NCU03351Uncharacterized protein. (937 aa)
NCU01572WD domain-containing protein. (856 aa)
NCU00494Uncharacterized protein. (804 aa)
NCU03564Flap structure-specific endonuclease. (1037 aa)
NCU03860mRNA stability protein; Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway. (167 aa)
pp4Serine/threonine-protein phosphatase. (423 aa)
camk-2Calcium/calmodulin-dependent protein kinase type I; Belongs to the protein kinase superfamily. (466 aa)
mdk-1Cyclin-dependent protein kinase; Belongs to the protein kinase superfamily. (337 aa)
mak-1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (413 aa)
cdc28Cell division control protein 2; Belongs to the protein kinase superfamily. (328 aa)
sad-1RNA dependent RNA polymerase. (1638 aa)
rrp3RNA-dependent RNA polymerase. (1351 aa)
NCU01182Uncharacterized protein. (144 aa)
cpc-3Cpc-3 protein. (1646 aa)
mrc1MRC1. (1464 aa)
stk-29Protein kinase. (1077 aa)
NCU01377Anaphase-promoting complex subunit Cut9. (654 aa)
NCU06710ClpTM1 domain-containing protein. (657 aa)
tngSerine/threonine-protein phosphatase. (388 aa)
mus-8Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
NCU04577Uncharacterized protein. (443 aa)
cdc7Cell cycle protein kinase. (526 aa)
NCU11300RING finger domain-containing protein. (106 aa)
NCU00488Protein phosphatase PP2A regulatory subunit A. (635 aa)
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A
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