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NCU05419 NCU05419 NCU10110 NCU10110 NCU11381 NCU11381 NCU01147 NCU01147 trp-2 trp-2 NCU09930 NCU09930 trp-1 trp-1 pyr-4 pyr-4 spe-1 spe-1 phr phr acu-3 acu-3 cfp cfp fba fba NCU05151 NCU05151 his-6 his-6 uvs-3 uvs-3 PSD1 PSD1 spe-2 spe-2 PSD2 PSD2 NCU06761 NCU06761 acu-6 acu-6 NCU00498 NCU00498 mig-11 mig-11 NCU06479 NCU06479 NCU06417 NCU06417 NCU04401 NCU04401 NCU09532 NCU09532 NCU09999 NCU09999 NCU09844 NCU09844 NCU05983 NCU05983 NCU05977 NCU05977 NCU09703 NCU09703 ilv-5 ilv-5 NCU06058 NCU06058 NCU06123 NCU06123 NCU06112 NCU06112 NCU04744 NCU04744 NCU08275 NCU08275 NCU07944 NCU07944 NCU06803 NCU06803 NCU02771 NCU02771 NCU00865 NCU00865 NCU02481 NCU02481 NCU02734 NCU02734 thr-5 thr-5 NCU03194 NCU03194 NCU00678 NCU00678 cry cry NCU04246 NCU04246 NCU16769 NCU16769 vad-2 vad-2 NCU02941 NCU02941
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCU05419Hydroxymethylglutaryl-CoA lyase. (399 aa)
NCU101103-hydroxyisobutyrate dehydrogenase. (449 aa)
NCU11381Diphosphomevalonate decarboxylase; Belongs to the diphosphomevalonate decarboxylase family. (394 aa)
NCU01147Tyrosine decarboxylase. (557 aa)
trp-2Anthranilate synthase component I. (582 aa)
NCU09930Folic acid synthesis protein. (548 aa)
trp-1Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. (762 aa)
pyr-4Orotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. (397 aa)
spe-1Ornithine decarboxylase; Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis. (484 aa)
phrDeoxyribodipyrimidine photo-lyase; Involved in repair of UV radiation-induced DNA damage. Catalyzes the light-dependent monomerization (300-600 nm) of cyclobutyl pyrimidine dimers (in cis-syn configuration), which are formed between adjacent bases on the same DNA strand upon exposure to ultraviolet radiation. (615 aa)
acu-3Isocitrate lyase; Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2- methylisocitrate; Belongs to the isocitrate lyase/PEP mutase superfamily. Isocitrate lyase family. (548 aa)
cfpPyruvate decarboxylase. (570 aa)
fbaFructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (362 aa)
NCU05151Phosphoketolase. (815 aa)
his-6Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (553 aa)
uvs-3UVS-3. (969 aa)
PSD1Phosphatidylserine decarboxylase proenzyme 1, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type I sub-subfamily. (532 aa)
spe-2S-adenosylmethionine decarboxylase. (503 aa)
PSD2Phosphatidylserine decarboxylase 2 alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine. Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Eukaryotic type II sub-subfamily. (1062 aa)
NCU06761Sphingosine-1-phosphate lyase. (576 aa)
acu-6Phosphoenolpyruvate carboxykinase (ATP); Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (605 aa)
NCU00498Molybdenum cofactor biosynthesis protein 1 B. (808 aa)
mig-11Carboxyvinyl-carboxyphosphonate phosphorylmutase. (315 aa)
NCU06479Uncharacterized protein. (363 aa)
NCU06417Uracil-5-carboxylate decarboxylase; Belongs to the metallo-dependent hydrolases superfamily. (394 aa)
NCU04401Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (288 aa)
NCU09532L-threo-3-deoxy-hexulosonate aldolase; Belongs to the DapA family. (327 aa)
NCU09999RIBOSOMAL_L9 domain-containing protein. (300 aa)
NCU09844Amidohydrolase; Belongs to the metallo-dependent hydrolases superfamily. (388 aa)
NCU059833,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (236 aa)
NCU05977Dihydrodipicolinate synthase. (372 aa)
NCU09703Acetolactate decarboxylase. (238 aa)
ilv-5Pyruvate decarboxylase. (576 aa)
NCU06058Amidohydrolase 2; Belongs to the metallo-dependent hydrolases superfamily. (327 aa)
NCU06123Phosphoketolase. (827 aa)
NCU06112Glutamate decarboxylase. (545 aa)
NCU04744Dihydrodipicolinate synthetase. (376 aa)
NCU08275Aromatic-L-amino-acid decarboxylase. (508 aa)
NCU07944Deoxyribose-phosphate aldolase. (265 aa)
NCU06803Glutamate decarboxylase; Belongs to the group II decarboxylase family. (521 aa)
NCU02771Uroporphyrinogen decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (398 aa)
NCU00865Oxalate decarboxylase oxdC. (484 aa)
NCU02481Mitochondrial 2-methylisocitrate lyase. (618 aa)
NCU02734Citrate lyase beta subunit. (319 aa)
thr-5L-allo-threonine aldolase. (470 aa)
NCU03194Phosphoribosylaminoimidazole carboxylase; In the C-terminal section; belongs to the AIR carboxylase family. Class I subfamily. (633 aa)
NCU00678Glutamate decarboxylase; Belongs to the group II decarboxylase family. (604 aa)
cryPutative cryptochrome DASH, mitochondrial; May have a photoreceptor function; Belongs to the DNA photolyase class-1 family. (745 aa)
NCU04246Uncharacterized protein. (276 aa)
NCU16769Flavodoxin and radical SAM domain-containing protein. (780 aa)
vad-2VAD-2. (734 aa)
NCU02941Uncharacterized protein. (226 aa)
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A
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