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chs-6 chs-6 NCU07952 NCU07952 NCU03905 NCU03905 fl fl nrc-2 nrc-2 con-8 con-8 con-10 con-10 con-13 con-13 chs-1 chs-1 con-6 con-6 cot-1 cot-1 rco-1 rco-1 chs-4 chs-4 hym-1 hym-1 nca-3 nca-3 NCU02610 NCU02610 pef-1 pef-1 NCU08319 NCU08319 cdc42 cdc42 gna-3 gna-3 cat-1 cat-1 uba4 uba4 eat-3 eat-3 NCU07592 NCU07592 gh76-4 gh76-4 NCU03532 NCU03532 NCU04601 NCU04601 nca-2 nca-2 Asm-1 Asm-1 gh76-7 gh76-7 NCU04264 NCU04264 gh76-2 gh76-2 NCU01064 NCU01064 NCU01033 NCU01033 gh76-1 gh76-1 gh76-5 gh76-5 NCU01109 NCU01109 sah-1 sah-1 bud6 bud6 NCU03552 NCU03552 NCU00086 NCU00086 vel vel NCU00399 NCU00399 hcp-1 hcp-1 stk-4 stk-4 NCU09219 NCU09219 gh76-6 gh76-6 gh76-3 gh76-3 NCU07005 NCU07005
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
chs-6Chitin synthase D. (899 aa)
NCU07952C2H2 type zinc finger domain-containing protein. (710 aa)
NCU03905BZIP domain-containing protein. (577 aa)
flConidial development protein fluffy; Required for conidiophore morphogenesis where it has a role in the budding phase. (792 aa)
nrc-2Serine/threonine-protein kinase nrc-2; Controls entry of the cell into the asexual developmental program. Required to repress entry into the conidiation program. (623 aa)
con-8Conidiation-specific protein 8. (176 aa)
con-10Conidiation-specific protein 10. (86 aa)
con-13Conidiation-specific protein 13. (340 aa)
chs-1Chitin synthase 1; Plays a major role in cell wall biogenesis. (917 aa)
con-6Conidiation-specific protein 6; May protect dormant spores from desiccation and play a significant role in the formation or survival of microconidia and ascospores; Belongs to the UPF0654 (con-6) family. (93 aa)
cot-1Serine/threonine-protein kinase cot-1; Protein kinase required for hyphal elongation; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. COT1 subfamily. (598 aa)
rco-1Transcriptional repressor rco-1; Represses transcription by RNA polymerase II. May be involved at several stages of conidiation and other growth and development processes. Appears to regulate genes that are expressed in asexual and sexual spore pathways. (604 aa)
chs-4Chitin synthase 4; Belongs to the chitin synthase family. Class IV subfamily. (1235 aa)
hym-1Conidiophore development protein hymA. (370 aa)
nca-3Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1152 aa)
NCU02610Dynein light chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in changing or maintaining the spatial distribution of cytoskeletal structures. (103 aa)
pef-1EF hand domain-containing protein. (311 aa)
NCU08319Developmental regulator flbA. (766 aa)
cdc42Rho-type GTPase. (196 aa)
gna-3Guanine nucleotide-binding protein alpha-3 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Involved in conidiation; Belongs to the G-alpha family. G(q) subfamily. (356 aa)
cat-1Catalase-1; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (736 aa)
uba4Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (486 aa)
eat-3AMI1 protein. (1988 aa)
NCU07592Uncharacterized protein. (589 aa)
gh76-4Mannan endo-1,6-alpha-mannosidase. (440 aa)
NCU03532Uncharacterized protein. (175 aa)
NCU04601Uncharacterized protein. (1040 aa)
nca-2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1449 aa)
Asm-1Cell pattern formation-associated protein asm-1; Transcription factor that regulates asexual reproduction. Binds the StuA-response elements (StRE) with the consensus sequence 5'-(A/T)CGCG(T/A)N(A/C)-3' at the promoters of target genes (By similarity). Required for rapid conidial germination, normal vegetative morphology, and protoperithecium formation ; Belongs to the EFG1/PHD1/stuA family. (643 aa)
gh76-7Mannan endo-1,6-alpha-mannosidase. (489 aa)
NCU04264Extracellular developmental signal biosynthesis protein FluG; Belongs to the glutamine synthetase family. (898 aa)
gh76-2Mannan endo-1,6-alpha-mannosidase. (456 aa)
NCU01064Uncharacterized protein. (92 aa)
NCU01033Uncharacterized protein. (940 aa)
gh76-1Glycosyl hydrolase family 76 protein. (824 aa)
gh76-5Mannan endo-1,6-alpha-mannosidase. (420 aa)
NCU01109Uncharacterized protein. (167 aa)
sah-1C2H2 transcription factor. (507 aa)
bud6Actin-interacting protein. (1051 aa)
NCU03552Uncharacterized protein. (379 aa)
NCU00086Glycosyl hydrolase. (331 aa)
velNon-specific serine/threonine protein kinase. (833 aa)
NCU00399Cell wall protein PhiA. (198 aa)
hcp-1Two-component system protein A. (925 aa)
stk-4Serine/threonine-protein kinase ste20; MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle. Phosphorylates histone H2B to form H2BS10ph (By similarity). Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (954 aa)
NCU09219Dopey domain-containing protein. (1922 aa)
gh76-6Mannan endo-1,6-alpha-mannosidase. (493 aa)
gh76-3Mannan endo-1,6-alpha-mannosidase. (478 aa)
NCU07005Glycosyl hydrolase. (420 aa)
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A
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