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NCU03415 NCU03415 NCU06441 NCU06441 ala ala NCU04072 NCU04072 NCU00316 NCU00316 NCU00299 NCU00299 NCU10016 NCU10016 NCU09305 NCU09305 NCU09058 NCU09058 NCU09648 NCU09648 NCU09646 NCU09646 NCU09402 NCU09402 NCU09391 NCU09391 NCU09553 NCU09553 kyn-1 kyn-1 nic-3 nic-3 NCU02438 NCU02438 NCU08126 NCU08126 NCU02383 NCU02383 NCU05752 NCU05752 NCU02291 NCU02291 acd-1 acd-1 NCU06120 NCU06120 cbs-2 cbs-2 NCU07053 NCU07053 NCU05624 NCU05624 NCU09864 NCU09864 NCU07064 NCU07064 NCU04727 NCU04727 NCU04796 NCU04796 NCU05537 NCU05537 NCU05499 NCU05499 NCU05559 NCU05559 NCU05558 NCU05558 NCU08877 NCU08877 NCU08771 NCU08771 NCU06801 NCU06801 gdh-1 gdh-1 qa-2 qa-2 lox lox aga-1 aga-1 for for fox-2 fox-2 fdh fdh NCU03372 NCU03372 NCU03348 NCU03348 NCU01751 NCU01751 NCU03913 NCU03913 NCU03903 NCU03903 acd-2 acd-2 NCU06647 NCU06647 NCU03777 NCU03777 NCU03761 NCU03761 acd-3 acd-3 NCU01106 NCU01106 NCU01071 NCU01071 NCU01281 NCU01281 NCU07958 NCU07958 NCU06543 NCU06543 NCU06625 NCU06625 NCU06339 NCU06339 NCU07626 NCU07626 NCU07623 NCU07623 NCU06803 NCU06803 NCU00904 NCU00904 NCU08382 NCU08382 NCU00847 NCU00847 NCU03076 NCU03076 NCU03137 NCU03137 bna1 bna1 NCU02179 NCU02179 NCU02127 NCU02127 NCU02126 NCU02126 NCU09732 NCU09732 NCU09266 NCU09266 NCU00877 NCU00877 NCU02475 NCU02475 NCU02727 NCU02727 thr-5 thr-5 NCU08058 NCU08058 NCU08333 NCU08333 NCU02704 NCU02704 NCU02702 NCU02702 NCU02663 NCU02663 NCU02660 NCU02660 NCU02936 NCU02936 NCU02571 NCU02571 NCU00678 NCU00678 NCU00580 NCU00580 B23G1.170 B23G1.170 NCU09184 NCU09184 NCU08998 NCU08998 ota ota NCU02450 NCU02450 NCU04771 NCU04771 NCU16336 NCU16336 NCU16447 NCU16447 NCU08411 NCU08411 NCU09885 NCU09885 NCU00936 NCU00936 NCU02941 NCU02941 NCU02998 NCU02998 NCU06448 NCU06448 NCU00378 NCU00378 kyn-2 kyn-2 NCU08004 NCU08004 NCU05419 NCU05419 NCU06559 NCU06559
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCU03415Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (494 aa)
NCU06441D-lactate dehydrogenase 2. (551 aa)
alaAlanine aminotransferase. (566 aa)
NCU04072Catechol dioxygenase. (297 aa)
NCU00316Peroxisomal adenine nucleotide transporter 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (339 aa)
NCU00299Peroxisomal D3,D2-enoyl-CoA isomerase. (279 aa)
NCU10016Thermophilic desulfurizing enzyme family protein. (454 aa)
NCU09305Abhydrolase_3 domain-containing protein. (343 aa)
NCU09058Enoyl-CoA hydratase. (343 aa)
NCU09648Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (488 aa)
NCU096463-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (415 aa)
NCU09402Uncharacterized protein. (474 aa)
NCU09391Phenylalanine ammonia-lyase; Belongs to the PAL/histidase family. (762 aa)
NCU095533-hydroxybutyryl CoA dehydrogenase. (316 aa)
kyn-1Kynureninase 1; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (485 aa)
nic-3Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid. (512 aa)
NCU02438Dihydrolipoamide succinyltransferase. (423 aa)
NCU08126D-lactate dehydrogenase. (577 aa)
NCU02383Uncharacterized protein. (575 aa)
NCU05752Indoleamine 2,3-dioxygenase. (505 aa)
NCU02291Glutaryl-CoA dehydrogenase. (436 aa)
acd-1Acyl-CoA dehydrogenase. (546 aa)
NCU06120Uncharacterized protein. (166 aa)
cbs-2Putative serine hydroxymethyltransferase, mitochondrial; Interconversion of serine and glycine. (546 aa)
NCU07053Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (496 aa)
NCU05624L-asparaginase. (488 aa)
NCU098642-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (469 aa)
NCU07064L-galactonate dehydratase. (451 aa)
NCU04727Glucosamine-6-phosphate isomerase. (340 aa)
NCU047963-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (419 aa)
NCU05537Fumarylacetoacetase. (429 aa)
NCU05499Homogentisate 1,2-dioxygenase. (467 aa)
NCU05559Uncharacterized protein. (594 aa)
NCU055583-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (420 aa)
NCU08877Glycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (169 aa)
NCU08771Acetolactate synthase; Belongs to the TPP enzyme family. (608 aa)
NCU06801Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. (403 aa)
gdh-1NAD-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (1050 aa)
qa-2Catabolic 3-dehydroquinase; Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway; Belongs to the type-II 3-dehydroquinase family. (173 aa)
loxL-amino-acid oxidase. (696 aa)
aga-1Arginase; Belongs to the arginase family. (358 aa)
forSerine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine. (480 aa)
fox-2Peroxisomal hydratase-dehydrogenase-epimerase; Second trifunctional enzyme acting on the beta-oxidation pathway for fatty acids, possessing hydratase-dehydrogenase-epimerase activities. Converts trans-2-enoyl-CoA via D-3-hydroxyacyl-CoA to 3- ketoacyl-CoA. (894 aa)
fdhFormate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. (375 aa)
NCU03372Nonspecific lipid-transfer protein; Belongs to the thiolase-like superfamily. Thiolase family. (458 aa)
NCU03348Aldehyde dehydrogenase. (479 aa)
NCU01751ATP-binding cassette protein. (715 aa)
NCU039132-oxoisovalerate dehydrogenase beta subunit. (417 aa)
NCU03903Lipase/esterase. (496 aa)
acd-2Acyl-CoA dehydrogenase. (519 aa)
NCU06647Enoyl-CoA hydratase/isomerase. (290 aa)
NCU037773-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (508 aa)
NCU03761PALP domain-containing protein. (404 aa)
acd-3Acyl-CoA dehydrogenase family member 11. (451 aa)
NCU01106L-amino acid oxidase. (649 aa)
NCU01071Uncharacterized protein. (388 aa)
NCU01281Uncharacterized protein. (146 aa)
NCU07958Sporulation protein SPS19. (317 aa)
NCU06543Acyl-CoA dehydrogenase. (433 aa)
NCU06625Cysteine dioxygenase. (235 aa)
NCU06339APSES transcription factor Xbp1. (667 aa)
NCU07626Gluconokinase; Belongs to the gluconokinase GntK/GntV family. (223 aa)
NCU076232,2-dialkylglycine decarboxylase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (535 aa)
NCU06803Glutamate decarboxylase; Belongs to the group II decarboxylase family. (521 aa)
NCU00904D-lactate dehydrogenase. (595 aa)
NCU08382Peroxisomal half ABC transporter. (865 aa)
NCU00847Uncharacterized protein. (355 aa)
NCU03076Delta-1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family. (601 aa)
NCU03137Nuclear elongation and deformation protein 1. (843 aa)
bna13-hydroxyanthranilate 3,4-dioxygenase; Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate. (180 aa)
NCU02179D-lactate dehydrogenase. (580 aa)
NCU02127Methylcrotonoyl-CoA carboxylase subunit beta. (623 aa)
NCU02126Isovaleryl-CoA dehydrogenase. (482 aa)
NCU09732Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (430 aa)
NCU09266Methylmalonate-semialdehyde dehydrogenase. (583 aa)
NCU00877Uncharacterized protein. (118 aa)
NCU02475Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (1100 aa)
NCU02727Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (477 aa)
thr-5L-allo-threonine aldolase. (470 aa)
NCU080583-hydroxyacyl-CoA dehydrogenase. (622 aa)
NCU08333Cysteine proteinase 1, mitochondrial; Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity. (516 aa)
NCU02704Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (562 aa)
NCU02702Gluconokinase; Belongs to the gluconokinase GntK/GntV family. (238 aa)
NCU02663L-lysine 2,3-aminomutase. (530 aa)
NCU02660DUF962 domain-containing protein. (190 aa)
NCU02936Proline dehydrogenase; Converts proline to delta-1-pyrroline-5-carboxylate. (550 aa)
NCU02571Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
NCU00678Glutamate decarboxylase; Belongs to the group II decarboxylase family. (604 aa)
NCU00580Acyl-CoA thioesterase. (362 aa)
B23G1.1704-hydroxyphenylpyruvate dioxygenase. (412 aa)
NCU09184Indoleamine 2,3-dioxygenase. (571 aa)
NCU089984-aminobutyrate aminotransferase, variant 1; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (515 aa)
otaOrnithine aminotransferase. (452 aa)
NCU02450Threonine dehydratase. (584 aa)
NCU04771Fructosyl-amino acid oxidase, variant. (502 aa)
NCU163363-hydroxyacyl-CoA dehydrogenase. (616 aa)
NCU16447Uncharacterized protein. (136 aa)
NCU08411Aspartate aminotransferase. (428 aa)
NCU09885Acyl-CoA dehydrogenase, variant. (438 aa)
NCU00936Succinate-semialdehyde dehydrogenase. (536 aa)
NCU02941Uncharacterized protein. (226 aa)
NCU02998Nicotinate-nucleotide pyrophosphorylase [carboxylating]; Involved in the catabolism of quinolinic acid (QA). Belongs to the NadC/ModD family. (321 aa)
NCU06448Enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (299 aa)
NCU00378Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (546 aa)
kyn-2Kynureninase 2; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively; Belongs to the kynureninase family. (472 aa)
NCU08004Electron transfer flavoprotein alpha-subunit. (348 aa)
NCU05419Hydroxymethylglutaryl-CoA lyase. (399 aa)
NCU065593-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (338 aa)
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A
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