STRINGSTRING
cpc-2 cpc-2 NCU11228 NCU11228 NCU01539 NCU01539 NCU09479 NCU09479 NCU06237 NCU06237 NCU06269 NCU06269 NCU06252 NCU06252 NCU07658 NCU07658 NCU08023 NCU08023 NCU06969 NCU06969 NCU06989 NCU06989 NCU07707 NCU07707 iml1 iml1 NCU06584 NCU06584 NCU08268 NCU08268 dcl-1 dcl-1 NCU06524 NCU06524 NCU03613 NCU03613 NCU05602 NCU05602 NCU07061 NCU07061 NCU06122 NCU06122 NCU02259 NCU02259 NCU02244 NCU02244 NCU09565 NCU09565 NCU02347 NCU02347 nst-4 nst-4 NCU09540 NCU09540 NCU09541 NCU09541 nuo14 nuo14 NCU09302 NCU09302 NCU10028 NCU10028 NCU09904 NCU09904 NCU07814 NCU07814 NCU00237 NCU00237 mus-21 mus-21 NCU00283 NCU00283 NCU04012 NCU04012 nup-20 nup-20 stk-4 stk-4 NCU03956 NCU03956 cse-1 cse-1 NCU00389 NCU00389 NCU06479 NCU06479 NCU01699 NCU01699 NCU00472 NCU00472 NCU00434 NCU00434 NCU00441 NCU00441 NCU03356 NCU03356 NCU05064 NCU05064 NCU03564 NCU03564 NCU04092 NCU04092 NCU04549 NCU04549 NCU01823 NCU01823 pp4 pp4 os-1 os-1 NCU08706 NCU08706 NCU01099 NCU01099 NCU01183 NCU01183 cpc-3 cpc-3 NCU03668 NCU03668 dim-7 dim-7 NCU04268 NCU04268 NCU03790 NCU03790 NCU04213 NCU04213 NCU01112 NCU01112 NCU06668 NCU06668 NCU04168 NCU04168 tng tng NCU01798 NCU01798 leu-6 leu-6 cpc-1 cpc-1 nim-1 nim-1 mus-8 mus-8 rco-1 rco-1 cnb-1 cnb-1 gna-2 gna-2 NCU01584 NCU01584 NCU05242 NCU05242 spa2 spa2 NCU02057 NCU02057 NCU08319 NCU08319 NCU00879 NCU00879 NCU16511 NCU16511 rgb-1 rgb-1 NCU01659 NCU01659 NCU01679 NCU01679 NCU04105 NCU04105 NCU06389 NCU06389 NCU04376 NCU04376 rcm-1 rcm-1 NCU08331 NCU08331 NCU01465 NCU01465 NCU01122 NCU01122 ham-2 ham-2 NCU00376 NCU00376 NCU00320 NCU00320 NCU00091 NCU00091 tah-1 tah-1 pph-3 pph-3 mob1-1 mob1-1 NCU00696 NCU00696 NCU02524 NCU02524 msn-1 msn-1 amyc amyc NCU03029 NCU03029 NCU03237 NCU03237 NCU02725 NCU02725 NCU02592 NCU02592 NCU03101 NCU03101 NCU08632 NCU08632 NCU00563 NCU00563 cdc5 cdc5 NCU02044 NCU02044 NCU02173 NCU02173 NCU02853 NCU02853 NCU02112 NCU02112 ham-4 ham-4 NCU02787 NCU02787 NCU09332 NCU09332 NCU02120 NCU02120 NCU09381 NCU09381 NCU00905 NCU00905 NCU08597 NCU08597 NCU03246 NCU03246 NCU00520 NCU00520 nst-3 nst-3 dcl-2 dcl-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cpc-2Guanine nucleotide-binding protein subunit beta-like protein; Required to activate general amino acid control under conditions of amino acid limitation in the vegetative growth phase, and for formation of protoperithecia in preparation for the sexual phase of the life cycle of N.crassa. (316 aa)
NCU11228DUF1339 domain-containing protein. (1112 aa)
NCU01539Vacuolar morphogenesis protein AvaB. (1138 aa)
NCU09479Uncharacterized protein. (263 aa)
NCU06237Uncharacterized protein. (263 aa)
NCU06269FHA domain-containing protein. (790 aa)
NCU06252Uncharacterized protein. (811 aa)
NCU07658Protein transporter sec72. (1940 aa)
NCU08023Cytohesin-2. (1626 aa)
NCU06969Phosphoinositide 3-phosphate phosphatase. (714 aa)
NCU06989Senescence domain-containing protein. (518 aa)
NCU07707FNIP_N domain-containing protein. (1229 aa)
iml1Vacuolar membrane-associated protein iml1. (2004 aa)
NCU06584Uncharacterized protein. (633 aa)
NCU08268TOR signaling pathway regulator. (406 aa)
dcl-1ATP-dependent helicase dcl-1; Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS). Part of a broad host defense response against viral infection and transposons. Controls the expression of the non-LTR retrotransposon Tad in the African strain, Adiomopoume. (1584 aa)
NCU06524Protease inhibitor. (264 aa)
NCU03613Opy2 domain-containing protein. (425 aa)
NCU05602Uncharacterized protein. (607 aa)
NCU07061Uncharacterized protein. (177 aa)
NCU06122GTPase activating protein Sar1. (780 aa)
NCU02259UDENN FLCN/SMCR8-type domain-containing protein. (523 aa)
NCU02244C2 domain-containing protein. (592 aa)
NCU09565Uncharacterized protein; Belongs to the cytochrome P450 family. (554 aa)
NCU02347Sec7 domain-containing protein. (1607 aa)
nst-4Hst3p. (1327 aa)
NCU09540Methyltranfer_dom domain-containing protein. (601 aa)
NCU09541ACT_7 domain-containing protein. (437 aa)
nuo14NADH:ubiquinone oxidoreductase 14kD subunit. (121 aa)
NCU09302DNA damage-binding protein cmr1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes. (521 aa)
NCU10028Bax Inhibitor family protein. (352 aa)
NCU09904Glucan 1,3-beta-glucosidase. (473 aa)
NCU07814DUF89 domain-containing protein. (477 aa)
NCU00237cAMP-specific phosphodiesterase. (698 aa)
mus-21Serine/threonine-protein kinase tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability (By similarity). (2939 aa)
NCU00283Uncharacterized protein. (435 aa)
NCU04012CAP10 domain-containing protein. (538 aa)
nup-20Protein transport protein sec13; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport facto [...] (304 aa)
stk-4Serine/threonine-protein kinase ste20; MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle. Phosphorylates histone H2B to form H2BS10ph (By similarity). Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (954 aa)
NCU03956Plus3 domain-containing protein. (601 aa)
cse-1Neuronal calcium sensor 1. (190 aa)
NCU00389Developmentally regulated GTP-binding protein 1. (368 aa)
NCU06479Uncharacterized protein. (363 aa)
NCU01699Uncharacterized protein. (389 aa)
NCU00472CDC37. (490 aa)
NCU00434Protein phosphatase 2C isoform beta. (619 aa)
NCU00441Phosducin. (326 aa)
NCU03356Uncharacterized protein. (611 aa)
NCU05064C2H2 transcription factor. (785 aa)
NCU03564Flap structure-specific endonuclease. (1037 aa)
NCU04092N-acylethanolamine amidohydrolase. (625 aa)
NCU04549Cytochrome c oxidase assembly protein COX20, mitochondrial; Involved in the assembly of the cytochrome c oxidase complex. Belongs to the COX20 family. (225 aa)
NCU01823Two-component sensor protein histidine protein kinase. (2557 aa)
pp4Serine/threonine-protein phosphatase. (423 aa)
os-1Histidine kinase. (1298 aa)
NCU08706AAA family ATPase. (622 aa)
NCU01099GTP-binding protein GTR1. (409 aa)
NCU01183GTP-binding protein 1. (372 aa)
cpc-3Cpc-3 protein. (1646 aa)
NCU03668WD domain-containing protein. (792 aa)
dim-7Defective in methylation-7 protein. (666 aa)
NCU04268Uncharacterized protein. (411 aa)
NCU03790CID domain-containing protein. (727 aa)
NCU04213Progesterone binding protein; Belongs to the cytochrome b5 family. (121 aa)
NCU01112Lipid binding protein. (256 aa)
NCU06668Uncharacterized protein. (918 aa)
NCU04168GH16 domain-containing protein. (462 aa)
tngSerine/threonine-protein phosphatase. (388 aa)
NCU01798Uncharacterized protein. (889 aa)
leu-6Leucine--tRNA ligase, cytoplasmic; Belongs to the class-I aminoacyl-tRNA synthetase family. (1123 aa)
cpc-1Cross-pathway control protein 1; In N.crassa grown under amino acid starvation conditions, this protein is required for increasing the transcription of the genes coding for many amino acid biosynthetic pathways enzymes. This transcription factor binds and recognize the DNA sequence: 5'-TGACTC- 3'. (270 aa)
nim-1G2-specific protein kinase nim-1; Protein kinase that plays an important role in mitotic regulation. (858 aa)
mus-8Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)
rco-1Transcriptional repressor rco-1; Represses transcription by RNA polymerase II. May be involved at several stages of conidiation and other growth and development processes. Appears to regulate genes that are expressed in asexual and sexual spore pathways. (604 aa)
cnb-1Calcineurin subunit B; Regulatory subunit of calcineurin, a calcium-dependent, calmodulin stimulated protein phosphatase. Confers calcium sensitivity. (174 aa)
gna-2Guanine nucleotide-binding protein alpha-2 subunit; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems; Belongs to the G-alpha family. G(q) subfamily. (355 aa)
NCU01584Uncharacterized protein. (1012 aa)
NCU05242C2H2 finger domain-containing protein, variant. (1033 aa)
spa2Spa2-like protein, variant. (888 aa)
NCU02057Autoinducer 2 sensor kinase/phosphatase luxQ. (1414 aa)
NCU08319Developmental regulator flbA. (766 aa)
NCU00879WD domain-containing protein, variant. (352 aa)
NCU16511ADP-ribose 1''-phosphate phosphatase. (861 aa)
rgb-1Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (481 aa)
NCU01659DDENN domain-containing protein. (1226 aa)
NCU01679Uncharacterized protein. (624 aa)
NCU04105Rap-GAP domain-containing protein. (1655 aa)
NCU06389DUF625 domain-containing protein, variant. (976 aa)
NCU04376WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (489 aa)
rcm-1RCM-1, variant. (917 aa)
NCU08331Uncharacterized protein. (1008 aa)
NCU01465Uncharacterized protein. (1500 aa)
NCU01122Uncharacterized protein. (935 aa)
ham-2Hyphal anastamosis protein 2. (1105 aa)
NCU00376GTR/RAG family GTPase Gtr2. (427 aa)
NCU00320USP domain-containing protein; Belongs to the peptidase C19 family. (2567 aa)
NCU00091Zinc_ribbon_16 domain-containing protein. (1196 aa)
tah-1TAH-1. (659 aa)
pph-3Serine/threonine-protein phosphatase PP1; Belongs to the PPP phosphatase family. PP-1 subfamily. (308 aa)
mob1-1Probable maintenance of ploidy protein mob1; Belongs to the MOB1/phocein family. (219 aa)
NCU00696SH3 domain-containing protein. (329 aa)
NCU02524Rho GAP domain-containing protein. (1464 aa)
msn-1Cutinase G-box binding protein. (575 aa)
amycLIM and Rho-GAP domain-containing protein. (1279 aa)
NCU03029Uncharacterized protein. (623 aa)
NCU03237Mitotic check point protein. (536 aa)
NCU02725Uncharacterized protein. (984 aa)
NCU02592Chitin synthase activator. (1029 aa)
NCU03101Uncharacterized protein. (716 aa)
NCU08632WD_REPEATS_REGION domain-containing protein. (1445 aa)
NCU00563Uncharacterized protein. (449 aa)
cdc5Serine/threonine protein kinase. (1021 aa)
NCU02044Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. (395 aa)
NCU02173C6 zinc finger protein. (1235 aa)
NCU02853C2H2 type zinc finger domain-containing protein. (1024 aa)
NCU02112Uncharacterized protein. (1808 aa)
ham-4FHA domain-containing protein. (797 aa)
NCU02787Uncharacterized protein. (1241 aa)
NCU09332Mannosyltransferase PMTI. (774 aa)
NCU02120Uncharacterized protein. (1729 aa)
NCU09381RWD domain-containing protein. (227 aa)
NCU00905N-acylethanolamine amidohydrolase. (610 aa)
NCU08597Uncharacterized protein. (1513 aa)
NCU03246Tyrosine-protein phosphatase CDC14. (654 aa)
NCU00520Oxidoreductase. (663 aa)
nst-3SIR2 family histone deacetylase. (647 aa)
dcl-2ATP-dependent helicase dcl-2; Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS). Part of a broad host defense response against viral infection and transposons. Controls the expression of the non-LTR retrotransposon Tad in the African strain, Adiomopoume. (1534 aa)
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A
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