(40 nodes) Cellular divalent inorganic cation homeostasis network (Neurospora crassa)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NCU06200	DUF1682 domain-containing protein. (448 aa)
	NCU03145	Oxidative stress resistance. (522 aa)
	NCU03312	CorA family metal ion transporter. (822 aa)
	NCU00861	Uncharacterized protein. (491 aa)
	NCU01990	UPF0016 domain-containing protein. (505 aa)
	NCU00795	Membrane bound cation transporter; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (575 aa)
	NCU00916	Membrane bound cation transporter; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (794 aa)
	NCU06366	Vacuolar calcium ion transporter; Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (504 aa)
	NCU03238	Uncharacterized protein. (490 aa)
	NCU16538	Uncharacterized protein. (161 aa)
	NCU16539	Uncharacterized protein. (250 aa)
	NCU05243	F-box domain-containing protein. (636 aa)
	NCU16541	Uncharacterized protein. (332 aa)
	cax	Vacuolar calcium ion transporter; Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (507 aa)
	NCU08095	Uncharacterized protein. (245 aa)
	NCU11307	CCC1. (307 aa)
	NCU11312	CorA family metal ion transporter. (630 aa)
	NCU10144	SAM-dependent methyltransferase. (405 aa)
	NCU10143	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1346 aa)
	NCU03512	Uncharacterized protein. (451 aa)
	ena-1	Calcium-transporting ATPase 3; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1121 aa)
	NCU05156	Uncharacterized protein. (487 aa)
	NCU04207	Mechanosensitive ion channel protein. (904 aa)
	NCU03790	CID domain-containing protein. (727 aa)
	stk-55	Mechanosensitive ion channel protein. (1012 aa)
	NCU05360	Calcium permease; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (1146 aa)
	NCU08490	Uncharacterized protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (400 aa)
	pmr-1	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1025 aa)
	nca-1	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (997 aa)
	NCU04079	Uncharacterized protein. (1100 aa)
	NCU05015	Uncharacterized protein. (325 aa)
	NCU05066	Uncharacterized protein. (552 aa)
	NCU00029	ZIP metal ion transporter. (514 aa)
	NCU04987	Hemolysin-III channel protein Izh2. (335 aa)
	NCU04898	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1318 aa)
	NCU08166	MCU domain-containing protein. (493 aa)
	NCU01279	ER membrane protein. (437 aa)
	NCU07262	Uncharacterized protein. (604 aa)
	NCU07966	Calcium-transporting ATPase 3; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1109 aa)
	NCU07709	Cation efflux system protein czcD. (326 aa)

Your Current Organism:

Neurospora crassa

NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NCU00029	NCU07262	Q7RY76	Q7S953	ZIP metal ion transporter.	Uncharacterized protein.	0.665
NCU01990	nca-1	Q7SFP1	Q1K909	UPF0016 domain-containing protein.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.530
NCU01990	pmr-1	Q7SFP1	Q1K905	UPF0016 domain-containing protein.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.643
NCU03238	NCU04987	V5IPX5	Q7S0E1	Uncharacterized protein.	Hemolysin-III channel protein Izh2.	0.560
NCU04898	nca-1	Q7S1D7	Q1K909	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.402
NCU04898	pmr-1	Q7S1D7	Q1K905	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.417
NCU04987	NCU03238	Q7S0E1	V5IPX5	Hemolysin-III channel protein Izh2.	Uncharacterized protein.	0.560
NCU05360	NCU10143	Q1K8L3	A7UWZ1	Calcium permease; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	0.621
NCU05360	pmr-1	Q1K8L3	Q1K905	Calcium permease; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.596
NCU07262	NCU00029	Q7S953	Q7RY76	Uncharacterized protein.	ZIP metal ion transporter.	0.665
NCU07262	NCU07709	Q7S953	Q7S9J7	Uncharacterized protein.	Cation efflux system protein czcD.	0.439
NCU07709	NCU07262	Q7S9J7	Q7S953	Cation efflux system protein czcD.	Uncharacterized protein.	0.439
NCU10143	NCU05360	A7UWZ1	Q1K8L3	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	Calcium permease; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	0.621
NCU10143	NCU10144	A7UWZ1	A7UWZ0	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	SAM-dependent methyltransferase.	0.740
NCU10144	NCU10143	A7UWZ0	A7UWZ1	SAM-dependent methyltransferase.	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	0.740
cax	nca-1	V5ILA0	Q1K909	Vacuolar calcium ion transporter; Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.791
cax	pmr-1	V5ILA0	Q1K905	Vacuolar calcium ion transporter; Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	0.568
nca-1	NCU01990	Q1K909	Q7SFP1	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	UPF0016 domain-containing protein.	0.530
nca-1	NCU04898	Q1K909	Q7S1D7	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.	0.402
nca-1	cax	Q1K909	V5ILA0	Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium.	Vacuolar calcium ion transporter; Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family.	0.791

page 1 of 2

Server load: low (22%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2025

Credits

Access

Info

About