27 items (Neurospora crassa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

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Your Input:
	rco-1	Transcriptional repressor rco-1; Represses transcription by RNA polymerase II. May be involved at several stages of conidiation and other growth and development processes. Appears to regulate genes that are expressed in asexual and sexual spore pathways. (604 aa)
	cpc-2	Guanine nucleotide-binding protein subunit beta-like protein; Required to activate general amino acid control under conditions of amino acid limitation in the vegetative growth phase, and for formation of protoperithecia in preparation for the sexual phase of the life cycle of N.crassa. (316 aa)
	dim-7	Defective in methylation-7 protein. (666 aa)
	NCU03668	WD domain-containing protein. (792 aa)
	cpc-3	Cpc-3 protein. (1646 aa)
	NCU01183	GTP-binding protein 1. (372 aa)
	NCU08706	AAA family ATPase. (622 aa)
	pp4	Serine/threonine-protein phosphatase. (423 aa)
	NCU03356	Uncharacterized protein. (611 aa)
	NCU00389	Developmentally regulated GTP-binding protein 1. (368 aa)
	NCU03956	Plus3 domain-containing protein. (601 aa)
	NCU07814	DUF89 domain-containing protein. (477 aa)
	NCU09302	DNA damage-binding protein cmr1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes. (521 aa)
	nst-4	Hst3p. (1327 aa)
	nst-3	SIR2 family histone deacetylase. (647 aa)
	NCU00520	Oxidoreductase. (663 aa)
	NCU09381	RWD domain-containing protein. (227 aa)
	NCU09332	Mannosyltransferase PMTI. (774 aa)
	NCU02044	Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP. (395 aa)
	NCU03101	Uncharacterized protein. (716 aa)
	msn-1	Cutinase G-box binding protein. (575 aa)
	NCU03029	Uncharacterized protein. (623 aa)
	rcm-1	RCM-1, variant. (917 aa)
	NCU06389	DUF625 domain-containing protein, variant. (976 aa)
	NCU01679	Uncharacterized protein. (624 aa)
	cpc-1	Cross-pathway control protein 1; In N.crassa grown under amino acid starvation conditions, this protein is required for increasing the transcription of the genes coding for many amino acid biosynthetic pathways enzymes. This transcription factor binds and recognize the DNA sequence: 5'-TGACTC- 3'. (270 aa)
	mus-8	Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation; Belongs to the ubiquitin-conjugating enzyme family. (151 aa)

Your Current Organism:

Neurospora crassa

NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NCU00389	NCU01183	Q7RYS1	Q1K853	Developmentally regulated GTP-binding protein 1.	GTP-binding protein 1.	0.598
NCU00389	NCU09381	Q7RYS1	Q7SCW3	Developmentally regulated GTP-binding protein 1.	RWD domain-containing protein.	0.943
NCU00389	cpc-2	Q7RYS1	Q01369	Developmentally regulated GTP-binding protein 1.	Guanine nucleotide-binding protein subunit beta-like protein; Required to activate general amino acid control under conditions of amino acid limitation in the vegetative growth phase, and for formation of protoperithecia in preparation for the sexual phase of the life cycle of N.crassa.	0.663
NCU01183	NCU00389	Q1K853	Q7RYS1	GTP-binding protein 1.	Developmentally regulated GTP-binding protein 1.	0.598
NCU01183	NCU09381	Q1K853	Q7SCW3	GTP-binding protein 1.	RWD domain-containing protein.	0.996
NCU01183	cpc-2	Q1K853	Q01369	GTP-binding protein 1.	Guanine nucleotide-binding protein subunit beta-like protein; Required to activate general amino acid control under conditions of amino acid limitation in the vegetative growth phase, and for formation of protoperithecia in preparation for the sexual phase of the life cycle of N.crassa.	0.575
NCU01679	NCU03668	V5IPI1	Q1K814	Uncharacterized protein.	WD domain-containing protein.	0.621
NCU01679	NCU09302	V5IPI1	Q7S1H9	Uncharacterized protein.	DNA damage-binding protein cmr1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	0.748
NCU03356	mus-8	Q7RXE0	P52493	Uncharacterized protein.	Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation; Belongs to the ubiquitin-conjugating enzyme family.	0.461
NCU03668	NCU01679	Q1K814	V5IPI1	WD domain-containing protein.	Uncharacterized protein.	0.621
NCU03668	NCU09302	Q1K814	Q7S1H9	WD domain-containing protein.	DNA damage-binding protein cmr1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	0.708
NCU03668	cpc-2	Q1K814	Q01369	WD domain-containing protein.	Guanine nucleotide-binding protein subunit beta-like protein; Required to activate general amino acid control under conditions of amino acid limitation in the vegetative growth phase, and for formation of protoperithecia in preparation for the sexual phase of the life cycle of N.crassa.	0.549
NCU03668	mus-8	Q1K814	P52493	WD domain-containing protein.	Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation; Belongs to the ubiquitin-conjugating enzyme family.	0.626
NCU03668	rco-1	Q1K814	P78706	WD domain-containing protein.	Transcriptional repressor rco-1; Represses transcription by RNA polymerase II. May be involved at several stages of conidiation and other growth and development processes. Appears to regulate genes that are expressed in asexual and sexual spore pathways.	0.584
NCU03956	mus-8	Q7RZB2	P52493	Plus3 domain-containing protein.	Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation; Belongs to the ubiquitin-conjugating enzyme family.	0.557
NCU06389	pp4	V5INY8	Q7RVY0	DUF625 domain-containing protein, variant.	Serine/threonine-protein phosphatase.	0.988
NCU09302	NCU01679	Q7S1H9	V5IPI1	DNA damage-binding protein cmr1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	Uncharacterized protein.	0.748
NCU09302	NCU03668	Q7S1H9	Q1K814	DNA damage-binding protein cmr1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes.	WD domain-containing protein.	0.708
NCU09381	NCU00389	Q7SCW3	Q7RYS1	RWD domain-containing protein.	Developmentally regulated GTP-binding protein 1.	0.943
NCU09381	NCU01183	Q7SCW3	Q1K853	RWD domain-containing protein.	GTP-binding protein 1.	0.996

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