Your Input: | |
| | NCU05341 | Endo/exonuclease/phosphatase domain-containing protein. (299 aa) |
| | NCU06222 | Tyrosyl-DNA phosphodiesterase domain-containing protein. (691 aa) |
| | stk-14 | Serine/threonine kinase IREI. (1208 aa) |
| | NCU09161 | Protein DOM34 homolog; May function in recognizing stalled ribosomes and triggering endonucleolytic cleavage of the mRNA, a mechanism to release non- functional ribosomes and degrade damaged mRNAs. (407 aa) |
| | NCU09001 | CCR4-NOT transcription complex subunit 7. (572 aa) |
| | NCU07381 | DNA cross-link repair protein pso2/snm1. (1031 aa) |
| | NCU07559 | Uncharacterized protein. (499 aa) |
| | NCU05966 | DNA repair protein. (603 aa) |
| | NCU09826 | RNase III domain-containing protein. (267 aa) |
| | NCU11241 | Nuclease domain-containing protein. (379 aa) |
| | dnr-8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (394 aa) |
| | NCU11261 | Uncharacterized protein. (317 aa) |
| | NCU10622 | Uncharacterized protein. (221 aa) |
| | NCU03538 | Deoxyribonuclease tatD. (508 aa) |
| | NCU16026 | Laglidadg endonuclease. (480 aa) |
| | crp-7 | 40S ribosomal protein S21; Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Has a physiological role leading to 18S rRNA stability (By similarity). (87 aa) |
| | grn | Guanyl-specific ribonuclease N1. (153 aa) |
| | par-1 | PAN2-PAN3 deadenylation complex catalytic subunit pan2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein pabp-1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequen [...] (1310 aa) |
| | bI3 | Cytochrome b mRNA maturase bI3; Mitochondrial mRNA maturase required for splicing of intron 3 of the cytochrome b (cob) gene, containing its own coding sequence. In the C-terminal section; belongs to the LAGLIDADG endonuclease family. (477 aa) |
| | NCU09855 | Nicotianamine synthase. (339 aa) |
| | NCU09014 | Cleavage and polyadenylation specificity factor subunit 5. (264 aa) |
| | NCU08904 | 20S-pre-rRNA D-site endonuclease NOB1; Required for the synthesis of 40S ribosome subunits. Has a role in processing 20S pre-rRNA into the mature 18S rRNA, where it is required for cleavage at the 3' end of the mature 18S rRNA (D-site). Accompanies the 20S pre-rRNA from the nucleus to the cytoplasm. Belongs to the NOB1 family. (440 aa) |
| | NCU00232 | Lactamase_B_4 domain-containing protein. (1099 aa) |
| | NCU00293 | NADH pyrophosphatase. (511 aa) |
| | NCU00319 | Uncharacterized protein. (242 aa) |
| | NCU00334 | 3' exoribonuclease. (297 aa) |
| | NCU03956 | Plus3 domain-containing protein. (601 aa) |
| | NCU04408 | Uncharacterized protein. (355 aa) |
| | NCU06438 | DNA repair helicase RAD25. (862 aa) |
| | NCU00115 | rRNA-processing protein FCF2. (210 aa) |
| | NCU00030 | Endonuclease. (332 aa) |
| | NCU01696 | mRNA cleavage factor complex component Pcf11. (817 aa) |
| | NCU00426 | Lactamase_B domain-containing protein. (359 aa) |
| | NCU00427 | Uncharacterized protein. (801 aa) |
| | NCU01625 | DNA repair helicase RAD3. (806 aa) |
| | NCU05036 | Exonuclease domain-containing protein. (343 aa) |
| | NCU04348 | Ribosome biogenesis protein. (1160 aa) |
| | NCU03564 | Flap structure-specific endonuclease. (1037 aa) |
| | NCU04091 | Uncharacterized protein. (422 aa) |
| | NCU06409 | Ribosome biogenesis protein Kri1. (723 aa) |
| | NCU04548 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2259 aa) |
| | NCU04450 | Exonuclease V, mitochondrial; Single strand DNA specific 5' exonuclease involved in mitochondrial DNA replication and recombination. Releases dinucleotides as main products of catalysis. Has the capacity to slide across 5'double-stranded DNA or 5'RNA sequences and resumes cutting two nucleotides downstream of the double-stranded-to-single-stranded junction or RNA-to-DNA junction, respectively. (657 aa) |
| | mus-38 | MUS38. (960 aa) |
| | uvs-6 | UVS6. (1314 aa) |
| | NCU03765 | 3'-5' exonuclease/helicase. (753 aa) |
| | NCU16019 | Probable intron-encoded endonuclease 1; Mitochondrial DNA endonuclease involved in intron homing. (304 aa) |
| | NCU16011 | Probable intron-encoded endonuclease 4; Mitochondrial DNA endonuclease involved in intron homing. In the C-terminal section; belongs to the LAGLIDADG endonuclease family. (545 aa) |
| | NCU16010 | Probable intron-encoded endonuclease 3; Mitochondrial DNA endonuclease involved in intron homing. In the C-terminal section; belongs to the LAGLIDADG endonuclease family. (533 aa) |
| | NCU16009 | Probable intron-encoded endonuclease 2; Mitochondrial DNA endonuclease involved in intron homing. In the C-terminal section; belongs to the LAGLIDADG endonuclease family. (452 aa) |
| | bI1 | Probable intron-encoded endonuclease bI1; Mitochondrial DNA endonuclease involved in intron homing. (448 aa) |
| | NCU06780 | tRNA (Uracil-5-)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (642 aa) |
| | pold-1 | DNA polymerase. (1104 aa) |
| | gul-1 | Cell wall biogenesis protein phosphatase Ssd1. (1365 aa) |
| | NCU03682 | Endonuclease/exonuclease/phosphatase. (289 aa) |
| | pod-5 | Polarity defective-5. (922 aa) |
| | NCU04155 | Exosome component 1. (214 aa) |
| | NCU04159 | DUF652 domain-containing protein. (194 aa) |
| | NCU03747 | Uncharacterized protein. (374 aa) |
| | spo11 | Meiosis-specific topoisomerase Spo11. (466 aa) |
| | NCU06718 | Zinc knuckle domain-containing protein. (673 aa) |
| | NCU08945 | RNA exonuclease 3. (690 aa) |
| | NCU03662 | Uncharacterized protein. (745 aa) |
| | NCU01367 | Small nucleolar ribonucleoprotein complex subunit. (629 aa) |
| | NTH1 | Endonuclease III homolog; Bifunctional DNA N-glycosylase with associated apurinic/apyrimidinic (AP) lyase function that catalyzes the first step in base excision repair (BER), the primary repair pathway for the repair of oxidative DNA damage. The DNA N-glycosylase activity releases the damaged DNA base from DNA by cleaving the N-glycosidic bond, leaving an AP site. The AP lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination. Primarily recognizes and repairs oxidative base damage of pyrimidines. (835 aa) |
| | NCU08951 | H/ACA ribonucleoprotein complex subunit 2. (242 aa) |
| | NCU09194 | Nuclease S1. (324 aa) |
| | sms-2 | Meiotic silencing suppressor 2; Belongs to the argonaute family. (989 aa) |
| | NCU04009 | Exosome complex exonuclease Rrp4. (387 aa) |
| | NCU01502 | Small nucleolar ribonucleoprotein complex subunit. (554 aa) |
| | NCU01503 | Pre-rRNA processing protein Tsr1. (817 aa) |
| | NCU01524 | Ribosome biogenesis protein BRX1. (325 aa) |
| | NCU03409 | RNA lariat debranching enzyme. (617 aa) |
| | NCU01806 | 3' exoribonuclease. (391 aa) |
| | frh | FRQ-interacting RNA helicase. (1106 aa) |
| | mus-18 | UV-damage endonuclease; Endonuclease for the repair of UV-irradiated DNA. Involved in the excision of cyclobutane pyrimidine dimers (CPD) and 6-4 pyrimidine pyrimidones (6-4PP) which forms the UV damage repair (UVDR) pathway; Belongs to the uve1/UvsE family. (656 aa) |
| | mus-8 | Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation; Belongs to the ubiquitin-conjugating enzyme family. (151 aa) |
| | cyt-4 | Mitochondrial protein cyt-4; Required for RNA 5'- and 3'-end processing and splicing. May act on the RNA processing enzymes directly, or it may act on other regulatory molecules, which influence the activity or synthesis of these enzymes. (1117 aa) |
| | mip-1 | DNA polymerase gamma, mitochondrial; Involved in the replication of mitochondrial DNA. (1456 aa) |
| | NCU16705 | Chromo domain-containing protein. (145 aa) |
| | NCU00401 | Uncharacterized protein. (458 aa) |
| | qde-2 | Post-transcriptional silencing protein QDE-2. (1089 aa) |
| | NCU06869 | Cleavage and polyadenylation specificity factor subunit 2. (938 aa) |
| | NCU04749 | DNA replication helicase Dna2. (1727 aa) |
| | NCU17030 | Heterogeneous nuclear ribonucleoprotein HRP1. (670 aa) |
| | NCU16972 | Uncharacterized protein. (302 aa) |
| | NCU03338 | SAP domain-containing protein. (497 aa) |
| | NCU16328 | Uncharacterized protein. (254 aa) |
| | NCU16771 | Rpp14 family protein. (187 aa) |
| | NCU01961 | DNA lyase Apn2. (655 aa) |
| | NCU16891 | Uncharacterized protein. (294 aa) |
| | NCU04364 | PAP-associated domain-containing protein. (1187 aa) |
| | NCU09128 | DUF3453 domain-containing protein. (751 aa) |
| | NCU08705 | Uncharacterized protein. (1071 aa) |
| | NCU05375 | Uncharacterized protein. (1707 aa) |
| | NCU16387 | XPGI domain-containing protein. (226 aa) |
| | NCU01762 | Nucleolar RNAse III, variant. (352 aa) |
| | NCU16461 | Uncharacterized protein. (170 aa) |
| | NCU16377 | Oligoribonuclease. (198 aa) |
| | NCU16423 | Uncharacterized protein. (378 aa) |
| | NCU16422 | Uncharacterized protein. (79 aa) |
| | NCU02748 | rRNA-processing protein utp23, variant. (320 aa) |
| | NCU06089 | Exonuclease. (758 aa) |
| | NCU05750 | Ribonuclease H. (498 aa) |
| | trax | TRAX. (355 aa) |
| | NCU02256 | Exosome complex exonuclease Rrp6. (822 aa) |
| | nop9 | Nucleolar protein 9; RNA-binding nucleolar protein required for pre-rRNA processing. Involved in production of 18S rRNA and assembly of small ribosomal subunit (By similarity); Belongs to the NOP9 family. (775 aa) |
| | dbp-3 | ATP-dependent RNA helicase dbp-3; ATP-dependent RNA helicase required for 60S ribosomal subunit synthesis. Involved in efficient pre-rRNA processing, predominantly at site A3, which is necessary for the normal formation of 25S and 5.8S rRNAs (By similarity); Belongs to the DEAD box helicase family. DDX5/DBP2 subfamily. (614 aa) |
| | NCU07058 | Small nucleolar ribonucleoprotein complex subunit Utp14. (916 aa) |
| | NCU03311 | Polyadenylation factor subunit CstF64. (322 aa) |
| | mus-44 | Mating-type switching protein swi10. (405 aa) |
| | NCU03159 | 3' exoribonuclease. (357 aa) |
| | usb1 | U6 snRNA phosphodiesterase; Phosphodiesterase responsible for the U6 snRNA 3' end processing. Acts as an exoribonuclease (RNase) responsible for trimming the poly(U) tract of the last nucleotides in the pre-U6 snRNA molecule, leading to the formation of mature U6 snRNA; Belongs to the 2H phosphoesterase superfamily. USB1 family. (364 aa) |
| | NCU00570 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (112 aa) |
| | slx4 | Structure-specific endonuclease subunit slx4; Regulatory subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (1013 aa) |
| | NCU09077 | Rpr2 domain-containing protein. (267 aa) |
| | NCU00777 | Methyltransferase. (278 aa) |
| | NCU08553 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (130 aa) |
| | mrd-1 | Multiple RNA-binding domain-containing protein 1; Involved in pre-rRNA processing; Belongs to the RRM MRD1 family. (827 aa) |
| | mus-40 | DNA excision repair protein Rad2. (1269 aa) |
| | NCU08368 | Ribonuclease P complex subunit Pop2. (382 aa) |
| | yth-1 | mRNA 3'-end-processing protein yth-1; Component of the cleavage factor I (CF I) involved in pre- mRNA 3'-end processing; Belongs to the CPSF4/YTH1 family. (317 aa) |
| | NCU02961 | Exonuclease. (716 aa) |
| | NCU05253 | XPG_I_2 domain-containing protein. (574 aa) |
| | NCU05251 | DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (122 aa) |
| | dcl-1 | ATP-dependent helicase dcl-1; Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS). Part of a broad host defense response against viral infection and transposons. Controls the expression of the non-LTR retrotransposon Tad in the African strain, Adiomopoume. (1584 aa) |
| | NCU08660 | Ribonuclease P protein subunit. (248 aa) |
| | NCU08648 | Nuclease PA3. (306 aa) |
| | NCU05240 | SAP30_Sin3_bdg domain-containing protein. (219 aa) |
| | esf-2 | Pre-rRNA-processing protein esf-2; Involved in the small subunit (SSU) processome assembly and function, and in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2 (By similarity); Belongs to the ESF2/ABP1 family. (340 aa) |
| | NCU07041 | KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (320 aa) |
| | rex-4 | RNA exonuclease 4; Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs (By similarity); Belongs to the REXO4 family. (406 aa) |
| | NCU06371 | Mitochondrial ATP-dependent RNA helicase Suv3. (796 aa) |
| | NCU06345 | Tyrosyl-DNA phosphodiesterase. (661 aa) |
| | NCU08323 | Bystin. (480 aa) |
| | NCU08299 | 60S ribosomal protein L3. (439 aa) |
| | tsp-4 | Probable tRNA-splicing endonuclease subunit tsp-4; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant [...] (315 aa) |
| | fip-1 | Pre-mRNA polyadenylation factor fip-1; Pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase; Belongs to the FIP1 family. (423 aa) |
| | NCU07889 | Nudix hydrolase domain-containing protein. (907 aa) |
| | NCU06272 | Mito ribosomal protein S16. (1798 aa) |
| | slx1 | Structure-specific endonuclease subunit slx1; Catalytic subunit of the slx1-slx4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (402 aa) |
| | tsp-2 | Probable tRNA-splicing endonuclease subunit tsp-2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant [...] (633 aa) |
| | rnh-201 | Ribonuclease H2 subunit A; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. Participates in DNA replication. (317 aa) |
| | rrp-36 | rRNA biogenesis protein rrp-36; Component of the 90S pre-ribosome involved in the maturation of rRNAs. Required for early cleavages of the pre-RNAs in the 40S ribosomal subunit maturation pathway (By similarity). (332 aa) |
| | rai1 | Decapping nuclease rai1; Ribonuclease that specifically degrades pre-mRNAs with a defective 5' end cap and is part of a pre-mRNA capping quality control. Has decapping and pyrophosphohydrolase activities. Has decapping activity toward incomplete 5' end cap mRNAs such as unmethylated 5' end-capped RNA to release GpppN and 5' end monophosphate RNA. Also possesses RNA 5'-pyrophosphohydrolase activity by hydrolyzing the 5' end triphosphate to release pyrophosphates (By similarity). Belongs to the DXO/Dom3Z family. (412 aa) |
| | ccr4 | Glucose-repressible alcohol dehydrogenase transcriptional effector; Acts as catalytic component of the CCR4-NOT core complex, which in the nucleus seems to be a general transcription factor, and in the cytoplasm the major mRNA deadenylase involved in mRNA turnover. Ccr4 has 3'-5' RNase activity with a strong preference for polyadenylated substrates and also low exonuclease activity towards single-stranded DNA. Discovered because of its role in the control of ADH2 gene expression. It is required for the expression of genes involved in non-fermentative growth (By similarity); Belongs to [...] (793 aa) |
| | mus-23 | Double-strand break repair protein mus-23; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing (By similarity); Belongs to the MRE11/RAD32 family. (739 aa) |
| | NCU02675 | RNA-3'-phosphate cyclase. (406 aa) |
| | B18D24.40 | Periodic tryptophan protein 2 homolog; Belongs to the WD repeat PWP2 family. (899 aa) |
| | nop-58 | Nucleolar protein 58; Required for pre-18S rRNA processing. May bind microtubules (By similarity); Belongs to the NOP5/NOP56 family. (597 aa) |
| | exr-1 | 5'-3' exoribonuclease 2; Possesses 5'->3' exoribonuclease activity. Required for the processing of nuclear mRNA and rRNA precursors. May promote termination of transcription by RNA polymerase II (By similarity); Belongs to the 5'-3' exonuclease family. XRN2/RAT1 subfamily. (1072 aa) |
| | ysh-1 | Endoribonuclease ysh-1; Component of the cleavage factor I (CF I) involved in pre- mRNA 3'-end processing; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily. (850 aa) |
| | NCU00690 | Ribonuclease P complex subunit Pop1. (930 aa) |
| | NCU00693 | Exosome complex exonuclease RRP40. (246 aa) |
| | NCU02928 | Uncharacterized protein. (1196 aa) |
| | NCU07891 | Endo/exonuclease/phosphatase domain-containing protein. (446 aa) |
| | NCU06572 | zf-C2HE domain-containing protein. (299 aa) |
| | NCU06678 | 5'-3' exoribonuclease 1; Multifunctional protein that exhibits several independent functions at different levels of the cellular processes. 5'-3' exonuclease component of the nonsense-mediated mRNA decay (NMD) which is a highly conserved mRNA degradation pathway, an RNA surveillance system whose role is to identify and rid cells of mRNA with premature termination codons and thus prevents accumulation of potentially harmful truncated proteins. (1450 aa) |
| | NCU04740 | Uncharacterized protein. (434 aa) |
| | NCU03268 | RNase_PH domain-containing protein. (251 aa) |
| | NCU00812 | Exosome complex exonuclease RRP41. (273 aa) |
| | NCU00501 | Nucleolar complex protein 4. (547 aa) |
| | NCU02134 | Transcription factor. (880 aa) |
| | NCU03036 | Fanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (885 aa) |
| | NCU08602 | Uncharacterized protein. (87 aa) |
| | mus-81 | Crossover junction endonuclease mus-81; Interacts with eme-1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single- end invasion (SEI) (By similarity); Belongs to the XPF family. (645 aa) |
| | NCU08121 | Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (200 aa) |
| | NCU03065 | Mitotic control protein dis3; Belongs to the RNR ribonuclease family. (984 aa) |
| | NCU03051 | WD domain-containing protein. (964 aa) |
| | mus-43 | DNA repair protein rad14. (435 aa) |
| | dcl-2 | ATP-dependent helicase dcl-2; Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS). Part of a broad host defense response against viral infection and transposons. Controls the expression of the non-LTR retrotransposon Tad in the African strain, Adiomopoume. (1534 aa) |
