92 items (Neurospora crassa) - STRING interaction network

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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	NCU02937	Uncharacterized protein. (203 aa)
	trp-4	Anthranilate phosphoribosyltransferase. (436 aa)
	leu-2	3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (779 aa)
	Nic-7	S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates. (310 aa)
	NCU03935	Homoserine dehydrogenase. (365 aa)
	NCU10020	Methionine synthase. (385 aa)
	NCU09896	Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. (211 aa)
	NCU09545	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (681 aa)
	NCU08216	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (528 aa)
	mri-1	Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily. (388 aa)
	arg-10	Argininosuccinate lyase. (466 aa)
	NCU06117	Uncharacterized protein. (595 aa)
	cbs-2	Putative serine hydroxymethyltransferase, mitochondrial; Interconversion of serine and glycine. (546 aa)
	NCU07115	HET domain-containing protein. (622 aa)
	ilv-6	Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (405 aa)
	NCU07690	Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (613 aa)
	pyr-3	PyrABCN. (1832 aa)
	NCU07725	Chorismate mutase. (269 aa)
	asn-2	Asparagine synthetase domain-containing protein 1. (597 aa)
	NCU07941	Aspartate aminotransferase. (482 aa)
	NCU07623	2,2-dialkylglycine decarboxylase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (535 aa)
	utr4	Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (234 aa)
	NCU08117	Uncharacterized protein. (675 aa)
	NCU00536	Homoserine O-acetyltransferase. (525 aa)
	cys-11	Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the C-terminal section; belongs to the APS kinase family. (573 aa)
	mde-1	Methylthioribulose-1-phosphate dehydratase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). (258 aa)
	hom-1	Aspartate-semialdehyde dehydrogenase. (362 aa)
	leu-4	2-isopropylmalate synthase. (625 aa)
	NCU02005	Phosphoadenosine phosphosulfate reductase. (398 aa)
	NCU02004	Phosphoserine phosphatase. (496 aa)
	NCU00799	Homocysteine S-methyltransferase. (361 aa)
	NCU00780	D-lactate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (363 aa)
	lys-4	Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Catalyzes the NAD(+)-dependent cleavage of saccharopine to L- lysine and 2-oxoglutarate, the final step in the alpha-aminoadipate (AAA) pathway for lysin biosynthesis; Belongs to the AlaDH/PNT family. (372 aa)
	thr-5	L-allo-threonine aldolase. (470 aa)
	lys-7	Homoisocitrate dehydrogenase. (402 aa)
	arg-3	Carbamoyl-phosphate synthase large subunit. (1168 aa)
	cys-12	Cysteine synthase 2; Putative cysteine synthase that catalyzes the conversion of O-acetyl-L-serine (OAS) into cysteine, the last step in the cysteine biosynthesis pathway. However, in contrast to cysteine synthase cys-17, this CS-like protein may not function in cysteine biosynthesis. (456 aa)
	NCU00581	Phosphopantetheinyl transferase. (348 aa)
	gln-1	Glutamine synthetase. (362 aa)
	lys-4-2	Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (784 aa)
	pdx-1	Probable pyridoxal 5'-phosphate synthase subunit pdx-1; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by pdx-2. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme- catalyzed isomerization of RBP and G3P, respectively. Also plays an indirect role in resistance to singlet oxygen-generating photosensitizers. (308 aa)
	arg-8	Acetylornithine aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (461 aa)
	NCU00468	Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family. (445 aa)
	NCU16651	Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. (241 aa)
	ota	Ornithine aminotransferase. (452 aa)
	NCU00409	Chorismate mutase/prephenate dehydratase, variant. (388 aa)
	NCU02450	Threonine dehydratase. (584 aa)
	Arg-4	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate. (469 aa)
	trp-2	Anthranilate synthase component I. (582 aa)
	NCU03748	Saccharopine dehydrogenase. (448 aa)
	gdh	NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (454 aa)
	trp-1	Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. (762 aa)
	trp-3	Tryptophan synthase; In the C-terminal section; belongs to the TrpB family. (708 aa)
	arg-2	Carbamoyl-phosphate synthase arginine-specific small chain, mitochondrial. (453 aa)
	leu-1	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (368 aa)
	for	Serine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine. (480 aa)
	ilv-2	Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (402 aa)
	met-7	Cystathionine gamma-synthase; Catalyzes the formation of L-cystathionine from O-succinyl-L- homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction. In the absence of thiol, catalyzes gamma-elimination to form 2- oxobutanoate, succinate and ammonia (By similarity). (621 aa)
	arg-6	N-acetyl-gamma-glutamyl-phosphate reductase; In the N-terminal section; belongs to the acetylglutamate kinase family. (871 aa)
	pro-1	Pyrroline-5-carboxylate reductase. (332 aa)
	NCU03425	Threonine synthase. (553 aa)
	arg-12	Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (385 aa)
	ilv-4	Acetolactate synthase small subunit. (330 aa)
	NCU05093	Cystathionine gamma-synthase. (657 aa)
	met-8	Methionine synthase. (769 aa)
	pro-3	Gamma-glutamyl phosphate reductase. (445 aa)
	NCU04303	Asparagine synthetase 2. (581 aa)
	NCU04292	Branched-chain-amino-acid aminotransferase. (414 aa)
	thr-4	Homoserine kinase. (358 aa)
	NCU03756	Aromatic amino acid aminotransferase 1. (688 aa)
	NCU03788	Cysteine synthase B. (525 aa)
	NCU03607	Threonine dehydratase catabolic. (388 aa)
	NCU03697	FAD binding domain-containing protein. (622 aa)
	NCU01071	Uncharacterized protein. (388 aa)
	arg-14	Amino-acid acetyltransferase, mitochondrial; N-acetylglutamate synthase involved in arginine biosynthesis. (712 aa)
	met-2	Cystathionine beta-lyase; Involved in de novo synthesis of methionine. Belongs to the trans-sulfuration enzymes family. (457 aa)
	NCU08434	5-methyltetrahydropteroyltriglutamate-homocysteine methyltransferase. (401 aa)
	cys-16	Cystathionine gamma-lyase. (417 aa)
	NCU01821	Alanine-glyoxylate aminotransferase. (446 aa)
	ser-7	Phosphoserine aminotransferase. (429 aa)
	his-7	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (257 aa)
	adi1	1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). (178 aa)
	pro-4	Glutamate 5-kinase. (468 aa)
	cys-17	Cysteine synthase 1; Catalyzes the conversion of O-succinyl-L-serine into cysteine, the last step in the cysteine biosynthesis pathway. Can also use O-acetyl-L-serine; Belongs to the cysteine synthase/cystathionine beta- synthase family. (376 aa)
	lys-5	Homocitrate synthase, variant 1; Belongs to the alpha-IPM synthase/homocitrate synthase family. (425 aa)
	gln-2	Glutamine synthetase. (394 aa)
	en(am)-2	Glutamate synthase, variant. (2116 aa)
	NCU17026	HET domain-containing protein. (153 aa)
	NCU06320	Uncharacterized protein. (687 aa)
	NCU07982	Acetolactate synthase. (689 aa)
	arg-1	Argininosuccinate synthase. (417 aa)
	NCU09116	Aromatic aminotransferase Aro8, variant. (560 aa)

Your Current Organism:

Neurospora crassa

NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Arg-4	NCU03425	A7UWD5	Q1K5C3	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.	Threonine synthase.	0.622
Arg-4	NCU07623	A7UWD5	Q7SB02	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.	2,2-dialkylglycine decarboxylase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.497
Arg-4	NCU07941	A7UWD5	Q7S9X7	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.	Aspartate aminotransferase.	0.904
Arg-4	arg-1	A7UWD5	V5IPG7	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.	Argininosuccinate synthase.	0.967
Arg-4	arg-10	A7UWD5	Q7S4I8	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.	Argininosuccinate lyase.	0.961
Arg-4	arg-12	A7UWD5	Q1K5I2	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.	Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.	0.991
Arg-4	arg-14	A7UWD5	Q1K8F6	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.	Amino-acid acetyltransferase, mitochondrial; N-acetylglutamate synthase involved in arginine biosynthesis.	0.997
Arg-4	arg-2	A7UWD5	P22572	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.	Carbamoyl-phosphate synthase arginine-specific small chain, mitochondrial.	0.731
Arg-4	arg-3	A7UWD5	Q7SH52	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.	Carbamoyl-phosphate synthase large subunit.	0.737
Arg-4	arg-6	A7UWD5	P54898	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.	N-acetyl-gamma-glutamyl-phosphate reductase; In the N-terminal section; belongs to the acetylglutamate kinase family.	0.999
Arg-4	arg-8	A7UWD5	Q9P3I3	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.	Acetylornithine aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.	0.993
Arg-4	cbs-2	A7UWD5	Q7S5N8	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.	Putative serine hydroxymethyltransferase, mitochondrial; Interconversion of serine and glycine.	0.473
Arg-4	en(am)-2	A7UWD5	V5IN94	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.	Glutamate synthase, variant.	0.542
Arg-4	for	A7UWD5	P34898	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.	Serine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine.	0.483
Arg-4	gdh	A7UWD5	P00369	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.	NADP-specific glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.925
Arg-4	his-7	A7UWD5	Q7RXQ8	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase.	0.576
Arg-4	hom-1	A7UWD5	Q7SF95	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.	Aspartate-semialdehyde dehydrogenase.	0.416
Arg-4	ota	A7UWD5	U9W8E1	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.	Ornithine aminotransferase.	0.895
Arg-4	pro-3	A7UWD5	Q1K6U2	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.	Gamma-glutamyl phosphate reductase.	0.628
Arg-4	pro-4	A7UWD5	Q7RYM2	Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate.	Glutamate 5-kinase.	0.649

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