STRINGSTRING
NCU02957 NCU02957 set-1 set-1 ysh-1 ysh-1 hel-1 hel-1 spb-4 spb-4 hel-2 hel-2 stk-1 stk-1 crc-1 crc-1 pxr-1 pxr-1 hat-2-2 hat-2-2 NCU02563 NCU02563 NCU02567 NCU02567 NCU02587 NCU02587 NCU01862 NCU01862 NCU02661 NCU02661 NCU02683 NCU02683 crf4-3 crf4-3 yth-1 yth-1 NCU02719 NCU02719 NCU02732 NCU02732 set-7 set-7 NCU02605 NCU02605 mrd-1 mrd-1 NCU02615 NCU02615 NCU02616 NCU02616 ssu-72 ssu-72 NCU00891 NCU00891 NCU00897 NCU00897 NCU00560 NCU00560 NCU00577 NCU00577 NCU09261 NCU09261 NCU09267 NCU09267 NCU07445 NCU07445 paa-3 paa-3 NCU03178 NCU03178 cen-T cen-T NCU03308 NCU03308 NCU03311 NCU03311 NCU03315 NCU03315 hda-2 hda-2 NCU02800 NCU02800 xan-1 xan-1 NCU09748 NCU09748 hda-3 hda-3 NCU00503 NCU00503 NCU02776 NCU02776 NCU02175 NCU02175 NCU03287 NCU03287 eaf6 eaf6 NCU03138 NCU03138 NCU03072 NCU03072 NCU02061 NCU02061 NCU02098 NCU02098 NCU09307 NCU09307 NCU09314 NCU09314 NCU03047 NCU03047 NCU03095 NCU03095 NCU03096 NCU03096 NCU09378 NCU09378 NCU09379 NCU09379 NCU09365 NCU09365 NCU03244 NCU03244 MED16 MED16 NCU00835 NCU00835 NCU08729 NCU08729 NCU08738 NCU08738 NCU09478 NCU09478 eaf-1 eaf-1 NCU06233 NCU06233 NCU02103 NCU02103 NCU02104 NCU02104 ad-5 ad-5 drc-1 drc-1 NCU03037 NCU03037 NCU03039 NCU03039 NCU09316 NCU09316 NCU09317 NCU09317 NCU09325 NCU09325 ctc-2 ctc-2 tcf-29 tcf-29 NCU00124 NCU00124 NCU00144 NCU00144 NCU06869 NCU06869 NCU03946 NCU03946 NCU03782 NCU03782 NCU04170 NCU04170 NCU17030 NCU17030 NCU09866 NCU09866 NCU01158 NCU01158 stk-47 stk-47 NCU03406 NCU03406 NCU10346 NCU10346 NCU03990 NCU03990 NCU16790 NCU16790 NCU08700 NCU08700 NCU03646 NCU03646 NCU02052 NCU02052 NCU02745 NCU02745 NCU09128 NCU09128 NCU02152 NCU02152 NCU02796 NCU02796 NCU02547 NCU02547 NCU02121 NCU02121 NCU00550 NCU00550 rtf-1 rtf-1 NCU02578 NCU02578 NCU03048 NCU03048 ccg-8 ccg-8 NCU01447 NCU01447 NCU03464 NCU03464 NCU01580 NCU01580 NCU01551 NCU01551 chap chap NCU01607 NCU01607 NCU01831 NCU01831 NCU01515 NCU01515 NCU07174 NCU07174 NCU07775 NCU07775 NCU04614 NCU04614 NCU09221 NCU09221 NCU09208 NCU09208 NCU08953 NCU08953 prk-3 prk-3 NCU06718 NCU06718 NCU04325 NCU04325 NCU06696 NCU06696 NCU03792 NCU03792 NCU04238 NCU04238 NCU04136 NCU04136 NCU03629 NCU03629 NCU01322 NCU01322 NCU01067 NCU01067 NCU01054 NCU01054 NCU06838 NCU06838 NCU06787 NCU06787 NCU02036 NCU02036 B5K2.060 B5K2.060 NCU03517 NCU03517 NCU01442 NCU01442 NCU03461 NCU03461 NCU05079 NCU05079 NCU04083 NCU04083 NCU08756 NCU08756 NCU04363 NCU04363 NCU00045 NCU00045 NCU00039 NCU00039 ctc-1 ctc-1 NCU04341 NCU04341 NCU05040 NCU05040 NCU00070 NCU00070 NCU00178 NCU00178 NCU00444 NCU00444 NCU00423 NCU00423 NCU01466 NCU01466 NCU00448 NCU00448 NCU01696 NCU01696 NCU04508 NCU04508 hda-1 hda-1 paa-1 paa-1 NCU04495 NCU04495 NCU04465 NCU04465 NCU04459 NCU04459 NCU05120 NCU05120 crc-2 crc-2 NCU00095 NCU00095 NCU00397 NCU00397 NCU06470 NCU06470 NCU06468 NCU06468 NCU06446 NCU06446 NCU06438 NCU06438 NCU06437 NCU06437 set-4 set-4 NCU04378 NCU04378 NCU03962 NCU03962 NCU03956 NCU03956 NCU00363 NCU00363 yaf9 yaf9 NCU00309 NCU00309 set-2 set-2 NCU09762 NCU09762 NCU09837 NCU09837 NCU07364 NCU07364 NCU06859 NCU06859 NCU06866 NCU06866 NCU09014 NCU09014 plc-1 plc-1 NCU08553 NCU08553 NCU07582 NCU07582 NCU07885 NCU07885 fip-1 fip-1 NCU08560 NCU08560 NCU07992 NCU07992 NCU08006 NCU08006 NCU08030 NCU08030 NCU08047 NCU08047 NCU06993 NCU06993 drc-2 drc-2 NCU06601 NCU06601 NCU06602 NCU06602 NCU07699 NCU07699 NCU06555 NCU06555 rex-4 rex-4 NCU07275 NCU07275 NCU05300 NCU05300 NCU05305 NCU05305 NCU07735 NCU07735 NCU08658 NCU08658 NCU08663 NCU08663 NCU05281 NCU05281 NCU05233 NCU05233 NCU08283 NCU08283 NCU04254 NCU04254 hat-2 hat-2 NCU04320 NCU04320 stk-18 stk-18 crf7-1 crf7-1 NCU01266 NCU01266 NCU01269 NCU01269 epl-1 epl-1 trf-2 trf-2 arp-6 arp-6 NCU05523 NCU05523 NCU05530 NCU05530 NCU04761 NCU04761 hat-6 hat-6 NCU05809 NCU05809 hat-5 hat-5 NCU04984 NCU04984 NCU07579 NCU07579 crf1-1 crf1-1 NCU09503 NCU09503 NCU07757 NCU07757 NCU09050 NCU09050 NCU05968 NCU05968 asf-1 asf-1 rna-14 rna-14 NCU05986 NCU05986 NCU05979 NCU05979 NCU09887 NCU09887 NCU09877 NCU09877 NCU05945 NCU05945 NCU05935 NCU05935 NCU07388 NCU07388 NCU07383 NCU07383 NCU09130 NCU09130 un-17 un-17 NCU07529 NCU07529 NCU09157 NCU09157 trf-3 trf-3 NCU06928 NCU06928 NCU06897 NCU06897 NCU06889 NCU06889 drc-3 drc-3 drc-4 drc-4 NCU02223 NCU02223 NCU05771 NCU05771 NCU02375 NCU02375 NCU06045 NCU06045 bdp-2 bdp-2 NCU11012 NCU11012 NCU10806 NCU10806 NCU11252 NCU11252 dnr-8 dnr-8 NCU11050 NCU11050 NCU11415 NCU11415 NCU03909 NCU03909 NCU06788 NCU06788 NCU01599 NCU01599
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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NCU02957BHLH domain-containing protein. (486 aa)
set-1Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. Belongs to the class V-like SAM-binding methyltransferase superfamily. (1313 aa)
ysh-1Endoribonuclease ysh-1; Component of the cleavage factor I (CF I) involved in pre- mRNA 3'-end processing; Belongs to the metallo-beta-lactamase superfamily. RNA- metabolizing metallo-beta-lactamase-like family. CPSF2/YSH1 subfamily. (850 aa)
hel-1RuvB-like helicase 1; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (458 aa)
spb-4ATP-dependent rRNA helicase spb-4; ATP-binding RNA helicase involved in the biogenesis of 60S ribosomal subunits. Binds 90S pre-ribosomal particles and dissociates from pre-60S ribosomal particles after processing of 27SB pre-rRNA. Required for the normal formation of 18S rRNA through the processing of pre-rRNAs at sites A0, A1 and A2, and the normal formation of 25S and 5.8S rRNAs through the processing of pre-rRNAs at sites C1 and C2. (654 aa)
hel-2RuvB-like helicase 2; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (481 aa)
stk-1Serine/threonine-protein kinase bur1; Serine/threonine-protein kinase involved in transcription regulation. Phosphorylates the mus-8/ubc2 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric-associated genes. Also required for histone H3 methylation. Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase (By similarity). (559 aa)
crc-1SWR1-complex protein 4; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (733 aa)
pxr-1Protein pxr-1; Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase; Belongs to the PINX1 family. (369 aa)
hat-2-2Histone acetyl transferase-2. (1116 aa)
NCU02563Transcription elongation factor S-II. (298 aa)
NCU02567Uncharacterized protein. (317 aa)
NCU02587RNA polymerase II transcription factor B subunit 3. (362 aa)
NCU01862SWIRM domain-containing protein FUN19. (404 aa)
NCU02661DNA-directed RNA polymerase II polypeptide. (171 aa)
NCU02683Uncharacterized protein. (738 aa)
crf4-3PWWP domain-containing protein. (640 aa)
yth-1mRNA 3'-end-processing protein yth-1; Component of the cleavage factor I (CF I) involved in pre- mRNA 3'-end processing; Belongs to the CPSF4/YTH1 family. (317 aa)
NCU02719BHLH domain-containing protein. (136 aa)
NCU02732Uncharacterized protein. (534 aa)
set-7SET-7. (1611 aa)
NCU02605DNA-directed RNA polymerase I/II/III subunit 10. (84 aa)
mrd-1Multiple RNA-binding domain-containing protein 1; Involved in pre-rRNA processing; Belongs to the RRM MRD1 family. (827 aa)
NCU02615Uncharacterized protein. (421 aa)
NCU02616WD-repeat containing protein slp1. (609 aa)
ssu-72RNA polymerase II subunit A C-terminal domain phosphatase ssu-72; Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (rpb-1); Belongs to the SSU72 phosphatase family. (266 aa)
NCU00891Xylitol dehydrogenase. (383 aa)
NCU00897Sin3 complex subunit. (924 aa)
NCU00560WD domain-containing protein. (412 aa)
NCU00577Uncharacterized protein. (398 aa)
NCU09261DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (221 aa)
NCU09267Copper radical oxidase. (1105 aa)
NCU07445Uncharacterized protein. (762 aa)
paa-3Protein cft1; RNA-binding component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation- dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and hrp1/CFIB. Involved in poly(A) site recognition. May be involved in coupling transcription termination and mRNA 3'-end formation (By similarity); Belongs to the CFT1 family. (1487 aa)
NCU03178PHD-type domain-containing protein. (580 aa)
cen-TCEN-T. (599 aa)
NCU03308Uncharacterized protein. (391 aa)
NCU03311Polyadenylation factor subunit CstF64. (322 aa)
NCU03315Uncharacterized protein. (407 aa)
hda-2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (499 aa)
NCU02800Arsenite resistance protein Ars2. (900 aa)
xan-1Alpha-ketoglutarate-dependent xanthine dioxygenase xan-1; Alpha-ketoglutarate-dependent xanthine dioxygenase is a non- heme mononuclear Fe(2+) enzyme that decarboxylates alpha-ketoglutarate to succinate and CO(2) while hydroxylating xanthine to generate uric acid. Allows xanthine utilization as a nitrogen source ; Belongs to the TfdA dioxygenase family. (420 aa)
NCU09748Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (115 aa)
hda-3Histone deacetylase RPD3. (658 aa)
NCU00503Nonselective cation channel protein. (781 aa)
NCU02776Cell division control protein; Belongs to the CDC6/cdc18 family. (691 aa)
NCU02175Phosphoinositide phospholipase C. (674 aa)
NCU03287Uncharacterized protein. (424 aa)
eaf6Chromatin modification-related protein eaf6; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (187 aa)
NCU03138Transcription initiation factor TFIID. (320 aa)
NCU03072SLD3 domain-containing protein. (1091 aa)
NCU02061WSC domain-containing protein. (225 aa)
NCU02098G/U mismatch-specific DNA glycosylase. (396 aa)
NCU09307Uncharacterized protein. (1094 aa)
NCU09314Uncharacterized protein. (576 aa)
NCU03047Uncharacterized protein. (345 aa)
NCU03095Transcription initiation factor TFIID subunit 7. (563 aa)
NCU03096Bromodomain associated domain-containing protein. (231 aa)
NCU09378DNA-directed RNA polymerase II polypeptide. (146 aa)
NCU09379Uncharacterized protein. (326 aa)
NCU09365YTH domain-containing protein. (707 aa)
NCU03244WD repeat protein. (571 aa)
MED16Mediator of RNA polymerase II transcription subunit 16; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1148 aa)
NCU00835Uncharacterized protein. (400 aa)
NCU08729Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (245 aa)
NCU08738MFS peptide transporter. (601 aa)
NCU09478Uncharacterized protein. (213 aa)
eaf-1Chromatin modification-related protein eaf-1; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (2189 aa)
NCU06233PHD domain-containing protein. (843 aa)
NCU02103DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1761 aa)
NCU02104WD domain-containing protein. (473 aa)
ad-5Bifunctional purine biosynthesis protein. (594 aa)
drc-1DNA replication complex GINS protein psf1; The GINS complex plays an essential role in the initiation of DNA replication. (216 aa)
NCU03037Uncharacterized protein. (200 aa)
NCU03039U2 snRNP auxiliary factor large subunit; Necessary for the splicing of pre-mRNA. Belongs to the splicing factor SR family. (584 aa)
NCU09316Uncharacterized protein. (788 aa)
NCU09317Uncharacterized protein. (652 aa)
NCU09325WD domain-containing protein. (766 aa)
ctc-2FACT complex subunit ctc-2; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (1032 aa)
tcf-29General transcription and DNA repair factor IIH subunit tcf-29; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has [...] (663 aa)
NCU00124Uncharacterized protein. (1568 aa)
NCU00144BHLH domain-containing protein. (494 aa)
NCU06869Cleavage and polyadenylation specificity factor subunit 2. (938 aa)
NCU03946Polyadenylate-binding protein 2, variant. (215 aa)
NCU03782DNA-directed RNA polymerase II subunit RPB11. (133 aa)
NCU04170Uncharacterized protein. (2119 aa)
NCU17030Heterogeneous nuclear ribonucleoprotein HRP1. (670 aa)
NCU09866Thyroid hormone receptor interactor 12. (2020 aa)
NCU01158Uncharacterized protein. (1038 aa)
stk-47Protein kinase. (1250 aa)
NCU03406Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (109 aa)
NCU10346Uncharacterized protein. (2592 aa)
NCU03990RRM domain-containing protein. (199 aa)
NCU16790CDC73_C domain-containing protein. (409 aa)
NCU08700Uncharacterized protein. (1043 aa)
NCU03646Uncharacterized protein; Belongs to the peroxidase family. (852 aa)
NCU02052Transcription initiation factor TFIId 127kD subunit, variant. (1870 aa)
NCU02745Uncharacterized protein. (379 aa)
NCU09128DUF3453 domain-containing protein. (751 aa)
NCU02152RRM domain-containing protein, variant. (379 aa)
NCU02796Chromatin modification-related protein. (663 aa)
NCU02547Thioredoxin-like_fold domain-containing protein. (276 aa)
NCU02121Transcriptional regulator. (633 aa)
NCU00550zf-C3H1 domain-containing protein. (1226 aa)
rtf-1General transcription and DNA repair factor IIH subunit rtf-1; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has b [...] (72 aa)
NCU02578Paired amphipathic helix protein Sin3a, variant. (1490 aa)
NCU03048CCCH zinc finger protein. (441 aa)
ccg-8Clock-controlled protein 8. (661 aa)
NCU01447Transcription elongation factor 1 homolog; Transcription elongation factor implicated in the maintenance of proper chromatin structure in actively transcribed regions. Belongs to the ELOF1 family. (138 aa)
NCU03464Transcription factor TFIID complex subunit Taf13. (215 aa)
NCU01580Transcription factor TFIIH subunit Tfb4. (439 aa)
NCU01551Uncharacterized protein. (312 aa)
chapCDP-2-and HDA-1 associating protein. (552 aa)
NCU01607Uncharacterized protein. (412 aa)
NCU01831General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (469 aa)
NCU01515DNA-directed RNA polymerase II polypeptide. (337 aa)
NCU07174SGF29 C-terminal domain-containing protein. (461 aa)
NCU07775TAFII28 domain-containing protein. (410 aa)
NCU0461460S ribosomal protein L19. (1126 aa)
NCU09221HIT finger domain-containing protein. (373 aa)
NCU09208Transcription factor SPT8. (702 aa)
NCU08953Uncharacterized protein. (485 aa)
prk-3Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (407 aa)
NCU06718Zinc knuckle domain-containing protein. (673 aa)
NCU04325Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (760 aa)
NCU06696Chromo domain-containing protein. (1464 aa)
NCU03792Inositol polyphosphate phosphatase. (1206 aa)
NCU04238Histone H1-binding protein. (471 aa)
NCU04136Transcription initiation factor TFIID subunit. (801 aa)
NCU03629Uncharacterized protein. (112 aa)
NCU01322Transcription factor TFIIE complex alpha subunit. (353 aa)
NCU01067CYCLIN domain-containing protein. (427 aa)
NCU01054TFIIA_gamma_C domain-containing protein. (285 aa)
NCU06838Uncharacterized protein. (648 aa)
NCU06787MRG domain-containing protein. (366 aa)
NCU02036tRNA-splicing endonuclease. (2130 aa)
B5K2.060FAS1 domain-containing protein NCU02579. (228 aa)
NCU03517Ski8. (342 aa)
NCU01442DUF1671 domain-containing protein. (530 aa)
NCU03461Chromatin modification-related protein. (824 aa)
NCU05079MFS peptide transporter. (629 aa)
NCU04083Uncharacterized protein. (831 aa)
NCU08756Uncharacterized protein. (443 aa)
NCU04363Uncharacterized protein. (690 aa)
NCU00045PHD finger domain-containing protein. (1261 aa)
NCU00039Uncharacterized protein. (622 aa)
ctc-1FACT complex subunit ctc-1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (565 aa)
NCU04341Uncharacterized protein. (1064 aa)
NCU05040GFA domain-containing protein. (297 aa)
NCU00070PHD-type domain-containing protein. (888 aa)
NCU00178RNA polymerase II elongator complex subunit. (401 aa)
NCU00444Transcription initiation factor TFIID subunit 14. (226 aa)
NCU00423PHD-type domain-containing protein. (1413 aa)
NCU01466Uncharacterized protein. (1015 aa)
NCU00448DUF4211 domain-containing protein. (726 aa)
NCU01696mRNA cleavage factor complex component Pcf11. (817 aa)
NCU04508Uncharacterized protein. (75 aa)
hda-1Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (744 aa)
paa-1Polyadenylation factor subunit 2; Required for 3'-end cleavage and polyadenylation of pre- mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle (By similarity). (660 aa)
NCU04495C-type cyclin. (442 aa)
NCU04465Nonselective cation channel protein. (743 aa)
NCU04459Transcriptional adapter 2; Functions as component of the transcription regulatory histone acetylation (HAT) complexes SAGA, SALSA and ADA. SAGA is involved in RNA polymerase II-dependent transcriptional regulation. (522 aa)
NCU05120DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1287 aa)
crc-2SWR1-complex protein 5; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability (By similarity). (342 aa)
NCU00095Tetratricopeptide repeat protein 1. (1279 aa)
NCU00397SGNH_hydro domain-containing protein. (260 aa)
NCU06470CID domain-containing protein. (373 aa)
NCU06468Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (4993 aa)
NCU06446Uncharacterized protein. (489 aa)
NCU06438DNA repair helicase RAD25. (862 aa)
NCU06437RING-type domain-containing protein. (1128 aa)
set-4SET-4. (948 aa)
NCU04378DNA replication initiation factor Cdc45. (874 aa)
NCU03962Mediator of RNA polymerase II transcription subunit 13; Component of the SRB8-11 complex. The SRB8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The SRB8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. (1542 aa)
NCU03956Plus3 domain-containing protein. (601 aa)
NCU00363Uncharacterized protein. (761 aa)
yaf9Protein AF-9 homolog; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised (By similarity). (309 aa)
NCU00309WSC domain-containing protein. (573 aa)
set-2Histone-lysine N-methyltransferase, H3 lysine-36 specific; Histone methyltransferase that trimethylates histone H3 'Lys- 36' forming H3K36me3. Involved in transcription elongation as well as in transcription repression; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (954 aa)
NCU09762Uncharacterized protein. (397 aa)
NCU09837Uncharacterized protein. (329 aa)
NCU07364Uncharacterized protein. (381 aa)
NCU06859Uncharacterized protein. (489 aa)
NCU06866Asparaginyl-tRNA synthetase. (604 aa)
NCU09014Cleavage and polyadenylation specificity factor subunit 5. (264 aa)
plc-1Phosphoinositide phospholipase C. (710 aa)
NCU08553DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (130 aa)
NCU07582Uncharacterized protein. (766 aa)
NCU07885WD repeat containing protein 82. (377 aa)
fip-1Pre-mRNA polyadenylation factor fip-1; Pre-mRNA polyadenylation factor that directly interacts with poly(A) polymerase; Belongs to the FIP1 family. (423 aa)
NCU08560Acyl_transf_3 domain-containing protein. (481 aa)
NCU07992Spt3. (562 aa)
NCU08006Uncharacterized protein. (727 aa)
NCU08030DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (152 aa)
NCU08047Uncharacterized protein. (784 aa)
NCU06993Ash2-trithorax family protein. (581 aa)
drc-2DNA replication complex GINS protein psf2; The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation (By similarity). (273 aa)
NCU06601Ion_trans domain-containing protein. (732 aa)
NCU06602Uncharacterized protein. (517 aa)
NCU07699Uncharacterized protein. (793 aa)
NCU06555Uncharacterized protein. (186 aa)
rex-4RNA exonuclease 4; Exoribonuclease involved in ribosome biosynthesis. Involved in the processing of ITS1, the internal transcribed spacer localized between the 18S and 5.8S rRNAs (By similarity); Belongs to the REXO4 family. (406 aa)
NCU07275Uncharacterized protein. (368 aa)
NCU05300WD_REPEATS_REGION domain-containing protein. (685 aa)
NCU05305DNA-directed RNA polymerase II polypeptide. (234 aa)
NCU07735Grp1p. (354 aa)
NCU08658C6 zinc finger domain-containing protein. (1120 aa)
NCU0866360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (519 aa)
NCU05281Uncharacterized protein. (298 aa)
NCU05233Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (452 aa)
NCU08283Integral membrane channel protein. (1265 aa)
NCU04254C3H1-type domain-containing protein. (1646 aa)
hat-2Histone acetyltransferase type B subunit 2; Regulatory subunit of the histone acetylase B (HAT-B) complex. The complex acetylates 'Lys-12' of histone H4 which is required for telomeric silencing. (446 aa)
NCU04320Transcriptional co-activator. (457 aa)
stk-18Histone acetylase complex subunit Paf400; Belongs to the PI3/PI4-kinase family. (3895 aa)
crf7-1Chromodomain-helicase-DNA-binding protein 4. (1726 aa)
NCU01266Phosphoinositide phospholipase C. (1151 aa)
NCU01269Cell cycle regulatory protein. (611 aa)
epl-1Enhancer of polycomb-like protein 1; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M (By similarity). (589 aa)
trf-2Transcription elongation factor spt4; The spt4-spt5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity). (120 aa)
arp-6Actin-related protein 6; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability (By similarity). (446 aa)
NCU05523RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (501 aa)
NCU05530Chromo domain-containing protein. (336 aa)
NCU04761Uncharacterized protein. (568 aa)
hat-6Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1188 aa)
NCU05809Uncharacterized protein. (377 aa)
hat-5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (742 aa)
NCU04984Uncharacterized protein. (339 aa)
NCU07579SCA7 domain-containing protein. (895 aa)
crf1-1Helicase swr-1; Catalytic component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling; Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily. (1845 aa)
NCU09503Uncharacterized protein. (1048 aa)
NCU07757Transcription initiation factor TFIID complex 60 kDa subunit. (465 aa)
NCU09050FAD binding domain-containing protein. (516 aa)
NCU05968Uncharacterized protein. (544 aa)
asf-1Histone chaperone asf-1; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. (271 aa)
rna-14mRNA 3'-end-processing protein rna-14; Component of the cleavage factor IA (CFIA) complex, which is involved in the endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation. (1167 aa)
NCU05986Sucrase/ferredoxin domain-containing protein. (381 aa)
NCU05979RXT2_N domain-containing protein. (580 aa)
NCU09887Drp1p. (338 aa)
NCU09877Uncharacterized protein. (424 aa)
NCU05945Uncharacterized protein. (408 aa)
NCU05935Uncharacterized protein. (540 aa)
NCU07388Uncharacterized protein. (564 aa)
NCU07383Transcriptional regulator Ngg1. (747 aa)
NCU09130Uncharacterized protein. (693 aa)
un-17Poly(A) polymerase; Polymerase that creates the 3'-poly(A) tail of mRNA's. (632 aa)
NCU07529Uncharacterized protein. (211 aa)
NCU09157Uncharacterized protein. (1312 aa)
trf-3Transcription elongation factor spt5; The spt4-spt5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity). (1054 aa)
NCU06928Uncharacterized protein. (853 aa)
NCU06897Uncharacterized protein. (356 aa)
NCU06889Uncharacterized protein. (532 aa)
drc-3DNA replication complex GINS protein psf3; The GINS complex plays an essential role in the initiation of DNA replication. (218 aa)
drc-4DNA replication regulator sld2; Has a role in the initiation of DNA replication. Required at S-phase checkpoint (By similarity); Belongs to the SLD2 family. (610 aa)
NCU02223TFIID_20kDa domain-containing protein. (836 aa)
NCU05771Uncharacterized protein. (291 aa)
NCU02375Ubiquitinyl hydrolase 1. (522 aa)
NCU06045WSC domain-containing protein. (315 aa)
bdp-2Transcriptional activator spt7. (1172 aa)
NCU11012DNA-directed RNA polymerase I. (160 aa)
NCU10806SAS4 domain-containing protein. (582 aa)
NCU11252Cyclin Pch1; Belongs to the cyclin family. (547 aa)
dnr-8Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (394 aa)
NCU11050DUF455 domain-containing protein. (1368 aa)
NCU11415Phosphoinositide phospholipase C. (624 aa)
NCU03909Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (302 aa)
NCU06788Chromo domain-containing protein. (145 aa)
NCU01599Uncharacterized protein. (570 aa)
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A
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