STRINGSTRING
rtf-1 rtf-1 stk-1 stk-1 NCU02587 NCU02587 NCU08006 NCU08006 NCU05523 NCU05523 NCU05771 NCU05771 NCU06438 NCU06438 NCU06470 NCU06470 NCU00397 NCU00397 NCU04495 NCU04495 NCU01067 NCU01067 prk-3 prk-3 NCU11252 NCU11252 NCU01580 NCU01580 NCU01831 NCU01831 stk-47 stk-47 tcf-29 tcf-29
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rtf-1General transcription and DNA repair factor IIH subunit rtf-1; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has b [...] (72 aa)
stk-1Serine/threonine-protein kinase bur1; Serine/threonine-protein kinase involved in transcription regulation. Phosphorylates the mus-8/ubc2 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric-associated genes. Also required for histone H3 methylation. Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase (By similarity). (559 aa)
NCU02587RNA polymerase II transcription factor B subunit 3. (362 aa)
NCU08006Uncharacterized protein. (727 aa)
NCU05523RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (501 aa)
NCU05771Uncharacterized protein. (291 aa)
NCU06438DNA repair helicase RAD25. (862 aa)
NCU06470CID domain-containing protein. (373 aa)
NCU00397SGNH_hydro domain-containing protein. (260 aa)
NCU04495C-type cyclin. (442 aa)
NCU01067CYCLIN domain-containing protein. (427 aa)
prk-3Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (407 aa)
NCU11252Cyclin Pch1; Belongs to the cyclin family. (547 aa)
NCU01580Transcription factor TFIIH subunit Tfb4. (439 aa)
NCU01831General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (469 aa)
stk-47Protein kinase. (1250 aa)
tcf-29General transcription and DNA repair factor IIH subunit tcf-29; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has [...] (663 aa)
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A
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