STRINGSTRING
stk-4 stk-4 stk-41 stk-41 vel vel stk-13 stk-13 stk-43 stk-43 apg-1 apg-1 stk-30 stk-30 nrc-1 nrc-1 stk-50 stk-50 camk-2 camk-2 prk-10 prk-10 mdk-1 mdk-1 mak-1 mak-1 cdc28 cdc28 pkac-1 pkac-1 os-4 os-4 cpc-3 cpc-3 cdc15 cdc15 stk-26 stk-26 stk-29 stk-29 prk-3 prk-3 prk-8 prk-8 stk-22 stk-22 stk-23 stk-23 Pkc Pkc nim-1 nim-1 cot-1 cot-1 nrc-2 nrc-2 cdc7 cdc7 NCU10043 NCU10043 NCU09202 NCU09202 stk-16 stk-16 camk-1 camk-1 pod-6 pod-6 stk-10 stk-10 os-5 os-5 ck-1a ck-1a camk-4 camk-4 un-1 un-1 stk-8 stk-8 stk-11 stk-11 stk-46 stk-46 stk-51 stk-51 stk-47 stk-47 stk-57 stk-57 prk-1 prk-1 mek-2 mek-2 mik-1 mik-1 ck-1b ck-1b mak-2 mak-2 hog-1 hog-1 cka cka stk-1 stk-1 pkac-2 pkac-2 stk-20 stk-20 NCU00978 NCU00978 dbf2 dbf2 cdc5 cdc5 prd-4 prd-4 ptk-2 ptk-2 mus-59 mus-59 stk-53 stk-53 stk-21 stk-21 prk-2 prk-2 stk-39 stk-39 stk-40 stk-40 camk-3 camk-3 stk-5 stk-5 stk-38 stk-38 prk-6 prk-6 stk-45 stk-45 stk-49 stk-49 stk-31 stk-31 stk-34 stk-34 stk-14 stk-14 stk-19 stk-19 stk-12 stk-12 stk-37 stk-37 stk-9 stk-9 fi fi prk-4 prk-4 mek-1 mek-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
stk-4Serine/threonine-protein kinase ste20; MAP4K component of the MAPK pathway required for the mating pheromone response and the regulation of cell polarity and cell cycle. Phosphorylates histone H2B to form H2BS10ph (By similarity). Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. (954 aa)
stk-41Serine/threonine protein kinase-41. (306 aa)
velNon-specific serine/threonine protein kinase. (833 aa)
stk-13Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (420 aa)
stk-43Serine/threonine protein kinase-43. (682 aa)
apg-1Serine/threonine-protein kinase apg-1; Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventin [...] (968 aa)
stk-30Protein kinase. (757 aa)
nrc-1MAPKK kinase. (914 aa)
stk-50Non-specific serine/threonine protein kinase. (644 aa)
camk-2Calcium/calmodulin-dependent protein kinase type I; Belongs to the protein kinase superfamily. (466 aa)
prk-10Non-specific serine/threonine protein kinase. (722 aa)
mdk-1Cyclin-dependent protein kinase; Belongs to the protein kinase superfamily. (337 aa)
mak-1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (413 aa)
cdc28Cell division control protein 2; Belongs to the protein kinase superfamily. (328 aa)
pkac-1cAMP-dependent protein kinase type 3. (536 aa)
os-4MAP kinase kinase kinase. (1367 aa)
cpc-3Cpc-3 protein. (1646 aa)
cdc15Cell division control protein 15. (1511 aa)
stk-26Protein kinase. (786 aa)
stk-29Protein kinase. (1077 aa)
prk-3Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (407 aa)
prk-8Serine/threonine-protein kinase MAK. (796 aa)
stk-22Serine/threonine protein kinase. (1246 aa)
stk-23Serine/threonine protein kinase. (921 aa)
PkcProtein kinase C-like; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1142 aa)
nim-1G2-specific protein kinase nim-1; Protein kinase that plays an important role in mitotic regulation. (858 aa)
cot-1Serine/threonine-protein kinase cot-1; Protein kinase required for hyphal elongation; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. COT1 subfamily. (598 aa)
nrc-2Serine/threonine-protein kinase nrc-2; Controls entry of the cell into the asexual developmental program. Required to repress entry into the conidiation program. (623 aa)
cdc7Cell cycle protein kinase. (526 aa)
NCU10043Mitotic spindle checkpoint component mad3. (1292 aa)
NCU09202Protein kinase dsk1. (578 aa)
stk-16Serine/threonine protein kinase. (1168 aa)
camk-1Ca/CaM-dependent kinase-1, variant 1; Belongs to the protein kinase superfamily. (413 aa)
pod-6Polarity-defective 6, variant 1. (928 aa)
stk-10Non-specific serine/threonine protein kinase. (753 aa)
os-5Mitogen activated protein kinase kinase, variant. (683 aa)
ck-1aCasein kinase I isoform delta; Belongs to the protein kinase superfamily. (384 aa)
camk-4Serine/threonine-protein kinase. (630 aa)
un-1Serine/threonine protein kinase. (620 aa)
stk-8Serine/threonine-protein kinase prk1. (557 aa)
stk-11Serine/threonine-protein kinase psk1, variant. (529 aa)
stk-46Serine/threonine protein kinase. (1405 aa)
stk-51Protein kinase. (763 aa)
stk-47Protein kinase. (1250 aa)
stk-57Serine/threonine protein kinase-57, variant 1. (879 aa)
prk-1Protein kinase gsk3, variant; Belongs to the protein kinase superfamily. (394 aa)
mek-2Mitogen activated protein kinase kinase 2. (511 aa)
mik-1MAP kinase kinase kinase. (1778 aa)
ck-1bCasein kinase 1b, variant; Belongs to the protein kinase superfamily. (441 aa)
mak-2Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (352 aa)
hog-1Mitogen-activated protein kinase hog-1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes. Involved in ion flux-mediated turgor regulation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily. (358 aa)
ckaCasein kinase II subunit alpha; Phosphorylates the frq clock protein thus regulating the circadian clock; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily. (336 aa)
stk-1Serine/threonine-protein kinase bur1; Serine/threonine-protein kinase involved in transcription regulation. Phosphorylates the mus-8/ubc2 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric-associated genes. Also required for histone H3 methylation. Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase (By similarity). (559 aa)
pkac-2Serine/threonine-protein kinase PRKX; Belongs to the protein kinase superfamily. (416 aa)
stk-20Serine/threonine protein kinase-20. (602 aa)
NCU00978Checkpoint protein kinase. (921 aa)
dbf2AGC/NDR protein kinase. (701 aa)
cdc5Serine/threonine protein kinase. (1021 aa)
prd-4Serine/threonine-protein kinase chk2. (702 aa)
ptk-2Serine/threonine protein kinase. (713 aa)
mus-59Serine/threonine-protein kinase. (1233 aa)
stk-53Serine/threonine protein kinase-53. (1233 aa)
stk-21Serine/threonine-protein kinase cbk1. (892 aa)
prk-2Protein kinase Yak1. (938 aa)
stk-39Serine/threonine protein kinase. (663 aa)
stk-40Serine/threonine protein kinase. (1221 aa)
camk-3Calcium/calmodulin-dependent protein kinase. (810 aa)
stk-5Serine/threonine-protein kinase hal4; Belongs to the protein kinase superfamily. (497 aa)
stk-38Serine/threonine protein kinase. (1115 aa)
prk-6Protein kinase. (492 aa)
stk-45Phosphoinositide 3-kinase regulatory subunit 4. (1563 aa)
stk-49Protein kinase. (638 aa)
stk-31Non-specific serine/threonine protein kinase. (869 aa)
stk-34Serine/threonine protein kinase-34. (815 aa)
stk-14Serine/threonine kinase IREI. (1208 aa)
stk-19Protein kinase domain-containing protein. (1145 aa)
stk-12Serine threonine protein kinase. (1943 aa)
stk-37Serine/threonine protein kinase-37. (522 aa)
stk-9Serine/threonine protein kinase-9; Belongs to the protein kinase superfamily. (412 aa)
fiProtein serine/threonine kinase; Belongs to the protein kinase superfamily. (489 aa)
prk-4Protein kinase lkh1. (732 aa)
mek-1MAP kinase kinase. (518 aa)
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A
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