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NCU01366 NCU01366 NCU01457 NCU01457 par-1 par-1 NCU03355 NCU03355 NCU04014 NCU04014 NCU03797 NCU03797 NCU03704 NCU03704 NCU01180 NCU01180 NCU01105 NCU01105 NCU05389 NCU05389 NCU00480 NCU00480 NCU04382 NCU04382 cpr-8 cpr-8 NCU00251 NCU00251 NCU08579 NCU08579 NCU09547 NCU09547 NCU02382 NCU02382 cpr-1 cpr-1 NCU02375 NCU02375 NCU02281 NCU02281 NCU05777 NCU05777 NCU09784 NCU09784 NCU04333 NCU04333 NCU01397 NCU01397 NCU01151 NCU01151 NCU06585 NCU06585 NCU00734 NCU00734 NCU08333 NCU08333 NCU01919 NCU01919 un-7 un-7 NCU00595 NCU00595 NCU00320 NCU00320 NCU04095 NCU04095 NCU12087 NCU12087 NCU06372 NCU06372 NCU02353 NCU02353 NCU08378 NCU08378
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCU01366ULP_PROTEASE domain-containing protein. (1335 aa)
NCU01457Ubiquitin C-terminal hydrolase; Belongs to the peptidase C19 family. (755 aa)
par-1PAN2-PAN3 deadenylation complex catalytic subunit pan2; Catalytic subunit of the poly(A)-nuclease (PAN) deadenylation complex, one of two cytoplasmic mRNA deadenylases involved in mRNA turnover. PAN specifically shortens poly(A) tails of RNA and the activity is stimulated by poly(A)-binding protein pabp-1. PAN deadenylation is followed by rapid degradation of the shortened mRNA tails by the CCR4-NOT complex. Deadenylated mRNAs are then degraded by two alternative mechanisms, namely exosome-mediated 3'-5' exonucleolytic degradation, or deadenlyation-dependent mRNA decaping and subsequen [...] (1310 aa)
NCU03355Calpain-5; Belongs to the peptidase C2 family. (836 aa)
NCU04014Uncharacterized protein. (1116 aa)
NCU03797Ubiquitin C-terminal hydrolase; Belongs to the peptidase C19 family. (1162 aa)
NCU03704Ubiquitin carboxyl-terminal hydrolase. (331 aa)
NCU01180Ubiquitin C-terminal hydrolase. (862 aa)
NCU01105ULP_PROTEASE domain-containing protein. (1750 aa)
NCU05389ULP_PROTEASE domain-containing protein. (1013 aa)
NCU00480Ubiquitin C-terminal hydrolase; Belongs to the peptidase C19 family. (1516 aa)
NCU04382TGc domain-containing protein. (684 aa)
cpr-8Calpain-like protease palB/cpr-8; Required for the proteolytic cleavage of the transcription factor pacc-1 in response to alkaline ambient pH. (932 aa)
NCU00251Calpain catalytic domain-containing protein; Belongs to the peptidase C2 family. (1007 aa)
NCU08579Ubiquitin carboxyl-terminal hydrolase. (621 aa)
NCU09547U4/U6.U5 tri-snRNP-associated protein 2. (560 aa)
NCU02382Ubiquitin carboxyl-terminal hydrolase. (522 aa)
cpr-1Cysteine protease 1; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Cleaves the C-terminal amino acid of apg-6/atg8 to reveal a C-terminal glycine. Apg-6/atg8 ubiquitin-like activity requires the exposure of the glycine at the C-terminus for its conjugation to [...] (506 aa)
NCU02375Ubiquitinyl hydrolase 1. (522 aa)
NCU02281USP domain-containing protein; Belongs to the peptidase C19 family. (1202 aa)
NCU05777Ubiquitin carboxyl-terminal hydrolase. (788 aa)
NCU09784Uncharacterized protein; Belongs to the arylamine N-acetyltransferase family. (310 aa)
NCU04333Ubiquitin C-terminal hydrolase; Belongs to the peptidase C19 family. (992 aa)
NCU01397OTU domain-containing protein. (328 aa)
NCU01151Calpain-B; Belongs to the peptidase C2 family. (1315 aa)
NCU06585Rad4 family protein. (1040 aa)
NCU00734Ulp1 protease. (257 aa)
NCU08333Cysteine proteinase 1, mitochondrial; Has aminopeptidase activity, shortening substrate peptides sequentially by 1 amino acid. Has bleomycin hydrolase activity, which can protect the cell from the toxic effects of bleomycin. Has homocysteine-thiolactonase activity, protecting the cell against homocysteine toxicity. (516 aa)
NCU01919Ubiquitin carboxyl-terminal hydrolase. (548 aa)
un-7Protein png-1; Belongs to the transglutaminase-like superfamily. PNGase family. (412 aa)
NCU00595Ubiquitin thiolesterase. (666 aa)
NCU00320USP domain-containing protein; Belongs to the peptidase C19 family. (2567 aa)
NCU04095SH3 domain-containing protein. (1326 aa)
NCU12087Nitrilase. (897 aa)
NCU06372Ubiquitin carboxyl-terminal hydrolase. (253 aa)
NCU02353OTU domain-containing protein. (316 aa)
NCU08378Ubiquitin carboxyl-terminal hydrolase. (849 aa)
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A
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