STRINGSTRING
nfh-2 nfh-2 NCU10030 NCU10030 NCU10043 NCU10043 nfh-1 nfh-1 NCU09813 NCU09813 NCU16422 NCU16422 NCU16423 NCU16423 NCU10376 NCU10376 NCU08345 NCU08345 NCU09240 NCU09240 NCU02588 NCU02588 NCU16400 NCU16400 NCU03337 NCU03337 NCU09319 NCU09319 un-1 un-1 rgb-1 rgb-1 NCU07206 NCU07206 NCU04212 NCU04212 NCU02150 NCU02150 NCU04376 NCU04376 NCU08700 NCU08700 NCU05195 NCU05195 NCU01145 NCU01145 NCU08948 NCU08948 NCU16767 NCU16767 NCU16756 NCU16756 NCU16757 NCU16757 NCU17061 NCU17061 NCU01278 NCU01278 NCU09860 NCU09860 NCU03820 NCU03820 NCU04749 NCU04749 NCU17268 NCU17268 NCU02420 NCU02420 NCU15831 NCU15831 NCU00089 NCU00089 NCU07519 NCU07519 NCU00401 NCU00401 NCU16705 NCU16705 NCU00470 NCU00470 NCU16653 NCU16653 lcm-2 lcm-2 kpr-1 kpr-1 hh2a hh2a B14D6.460 B14D6.460 hel-1 hel-1 cka cka ckb-1 ckb-1 ckb-2 ckb-2 5F3.150 5F3.150 hH2Az hH2Az hel-2 hel-2 B24N11.060 B24N11.060 kpr-4 kpr-4 vsp-3 vsp-3 NCU02539 NCU02539 NCU02587 NCU02587 stk-20 stk-20 NCU02932 NCU02932 NCU02940 NCU02940 NCU01896 NCU01896 NCU02683 NCU02683 NCU02687 NCU02687 NCU02965 NCU02965 NCU03190 NCU03190 NCU03207 NCU03207 NCU00949 NCU00949 pme-1 pme-1 NCU02742 NCU02742 NCU02496 NCU02496 NCU02616 NCU02616 NCU00800 NCU00800 NCU02011 NCU02011 pcn pcn cdc5 cdc5 NCU09261 NCU09261 NCU02079 NCU02079 hda-2 hda-2 prd-4 prd-4 NCU09744 NCU09744 eat-6 eat-6 NCU00517 NCU00517 NCU02776 NCU02776 ptk-2 ptk-2 NCU03291 NCU03291 NCU03137 NCU03137 NCU03073 NCU03073 myo-1 myo-1 NCU02114 NCU02114 ham-4 ham-4 NCU09814 NCU09814 drc-1 drc-1 qde-3 qde-3 NCU08604 NCU08604 NCU02791 NCU02791 MCM7 MCM7 mus-59 mus-59 NCU02758 NCU02758 NCU02828 NCU02828 NCU03246 NCU03246 NCU06767 NCU06767 NCU07870 NCU07870 NCU05705 NCU05705 stk-5 stk-5 atrx atrx NCU06216 NCU06216 NCU06269 NCU06269 prk-6 prk-6 NCU07655 NCU07655 NCU07991 NCU07991 ppm-1-2 ppm-1-2 NCU07998 NCU07998 NCU08009 NCU08009 NCU06988 NCU06988 drc-2 drc-2 NCU06331 NCU06331 NCU08317 NCU08317 NCU07313 NCU07313 NCU07321 NCU07321 NCU06611 NCU06611 NCU06623 NCU06623 NCU07679 NCU07679 kpr-2 kpr-2 NCU05194 NCU05194 NCU05296 NCU05296 rpa-2 rpa-2 stk-44 stk-44 NCU05280 NCU05280 NCU05282 NCU05282 NCU05250 NCU05250 cao-1 cao-1 NCU03825 NCU03825 csa csa NCU01269 NCU01269 NCU03840 NCU03840 NCU05513 NCU05513 NCU05536 NCU05536 NCU04784 NCU04784 NCU04738 NCU04738 NCU07078 NCU07078 NCU05781 NCU05781 NCU05820 NCU05820 NCU06098 NCU06098 NCU06144 NCU06144 NCU02232 NCU02232 jip5 jip5 NCU02411 NCU02411 drc-3 drc-3 NCU06894 NCU06894 NCU09038 NCU09038 NCU09706 NCU09706 stk-12 stk-12 NCU09439 NCU09439 NCU09062 NCU09062 NCU09063 NCU09063 NCU07400 NCU07400 NCU09297 NCU09297 NCU09500 NCU09500 NCU09503 NCU09503 NCU09855 NCU09855 fwd-2 fwd-2 NCU10155 NCU10155 NCU09422 NCU09422 NCU05907 NCU05907 NCU06942 NCU06942 NCU08903 NCU08903 NCU09982 NCU09982 NCU05972 NCU05972 fi fi NCU07554 NCU07554 NCU00243 NCU00243 NCU00273 NCU00273 mdm34 mdm34 NCU04007 NCU04007 NCU04058 NCU04058 NCU04378 NCU04378 div-4 div-4 NCU04428 NCU04428 NCU04437 NCU04437 stk-42 stk-42 stk-13 stk-13 NCU06481 NCU06481 NCU04463 NCU04463 NCU04513 NCU04513 NCU04535 NCU04535 PIF1 PIF1 NCU00435 NCU00435 NCU00199 NCU00199 NCU00205 NCU00205 crf4-1 crf4-1 NCU00081 NCU00081 stk-30 stk-30 hH4v hH4v NCU01572 NCU01572 NCU00051 NCU00051 NCU04083 NCU04083 fwd-1 fwd-1 NCU04548 NCU04548 NCU03860 NCU03860 NCU01304 NCU01304 NCU01247 NCU01247 NCU01248 NCU01248 mdk-1 mdk-1 NCU01702 NCU01702 NCU00424 NCU00424 ran ran cdc28 cdc28 cen-c cen-c NCU03765 NCU03765 NCU03001 NCU03001 fr fr NCU06776 NCU06776 NCU05459 NCU05459 NCU08427 NCU08427 NCU06851 NCU06851 NCU05433 NCU05433 NCU05385 NCU05385 NCU01067 NCU01067 NCU01171 NCU01171 pold-1 pold-1 NCU03681 NCU03681 NCU03735 NCU03735 NCU01303 NCU01303 NCU01323 NCU01323 NCU01340 NCU01340 NCU03597 NCU03597 rpa-1 rpa-1 NCU04131 NCU04131 NCU04153 NCU04153 NCU04232 NCU04232 NCU03763 NCU03763 naf-2 naf-2 NCU04302 NCU04302 spo11 spo11 NCU04319 NCU04319 mrc1 mrc1 stk-29 stk-29 NCU04327 NCU04327 NCU01370 NCU01370 NCU01387 NCU01387 NCU06644 NCU06644 NCU01290 NCU01290 prk-3 prk-3 NCU08951 NCU08951 NCU04665 NCU04665 NCU09217 NCU09217 NCU04618 NCU04618 NCU07146 NCU07146 NCU07192 NCU07192 NCU07222 NCU07222 NCU01746 NCU01746 NCU03528 NCU03528 NCU01824 NCU01824 NCU01791 NCU01791 ro-3 ro-3 tbg tbg pph-1 pph-1 nim-1 nim-1 erg-3 erg-3 tba-2 tba-2 tba-1 tba-1 hh2b hh2b ypt-1 ypt-1 ubi::crp-6 ubi::crp-6 ubi ubi tub-2 tub-2 ro-11 ro-11 NCU01090 NCU01090 NCU01242 NCU01242 cdc7 cdc7 NCU10430 NCU10430 NCU11331 NCU11331 NCU10467 NCU10467 dnr-8 dnr-8 msh4 msh4 mus-9 mus-9 NCU00488 NCU00488 rpa-3 rpa-3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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nfh-214-3-3 family protein 7; Belongs to the 14-3-3 family. (262 aa)
NCU10030Alpha-L-rhamnosidase C, variant. (822 aa)
NCU10043Mitotic spindle checkpoint component mad3. (1292 aa)
nfh-1DNA damage checkpoint protein rad24, variant; Belongs to the 14-3-3 family. (224 aa)
NCU09813SMT3, variant 1. (99 aa)
NCU16422Uncharacterized protein. (79 aa)
NCU16423Uncharacterized protein. (378 aa)
NCU10376Uncharacterized protein. (441 aa)
NCU08345Ubiquitin-conjugating enzyme E; Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
NCU09240Vezatin domain-containing protein. (658 aa)
NCU02588Nuclear movement protein nudC, variant 1. (191 aa)
NCU16400Uncharacterized protein. (431 aa)
NCU03337ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (483 aa)
NCU09319Uncharacterized protein. (805 aa)
un-1Serine/threonine protein kinase. (620 aa)
rgb-1Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (481 aa)
NCU07206Uncharacterized protein. (701 aa)
NCU04212Uncharacterized protein. (511 aa)
NCU02150Ser/Thr protein phosphatase. (571 aa)
NCU04376WD_REPEATS_REGION domain-containing protein; Belongs to the WD repeat SEC13 family. (489 aa)
NCU08700Uncharacterized protein. (1043 aa)
NCU05195Uncharacterized protein. (484 aa)
NCU01145Uncharacterized protein. (205 aa)
NCU08948NIF domain-containing protein, variant. (531 aa)
NCU16767Uncharacterized protein. (182 aa)
NCU16756Uncharacterized protein. (277 aa)
NCU16757H/ACA ribonucleoprotein complex subunit; Required for ribosome biogenesis. Part of a complex which catalyzes pseudouridylation of rRNA. This involves the isomerization of uridine such that the ribose is subsequently attached to C5, instead of the normal N1. Pseudouridine ("psi") residues may serve to stabilize the conformation of rRNAs. (220 aa)
NCU17061DnaJ domain-containing protein. (337 aa)
NCU01278Uncharacterized protein. (862 aa)
NCU09860Telomere silencing protein Zds1, variant. (870 aa)
NCU03820Checkpoint protein; Belongs to the HUS1 family. (371 aa)
NCU04749DNA replication helicase Dna2. (1727 aa)
NCU17268Uncharacterized protein. (286 aa)
NCU02420AAA family ATPase, variant; Belongs to the AAA ATPase family. (867 aa)
NCU15831Uncharacterized protein. (847 aa)
NCU00089MYND domain-containing protein, variant 1. (566 aa)
NCU07519ATP-dependent DNA helicase; Belongs to the helicase family. (813 aa)
NCU00401Uncharacterized protein. (458 aa)
NCU16705Chromo domain-containing protein. (145 aa)
NCU00470DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (484 aa)
NCU16653Uncharacterized protein. (210 aa)
lcm-2tRNA wybutosine-synthesizing protein 4; Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA. May methylate the carboxyl group of leucine residues to form alpha-leucine ester residues (By similarity); Belongs to the methyltransferase superfamily. LCMT family. (1213 aa)
kpr-1Probable kinetochore protein ndc80; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. (743 aa)
hh2aHistone H2A; Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (134 aa)
B14D6.460Replication factor C subunit 5; The elongation of primed DNA templates by DNA polymerase delta and epsilon requires the action of the accessory proteins proliferating cell nuclear antigen (PCNA) and activator 1. (352 aa)
hel-1RuvB-like helicase 1; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (458 aa)
ckaCasein kinase II subunit alpha; Phosphorylates the frq clock protein thus regulating the circadian clock; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily. (336 aa)
ckb-1Casein kinase II subunit beta-1; Plays a complex role in regulating the basal catalytic activity of the alpha subunit. (333 aa)
ckb-2Casein kinase II subunit beta-2; Plays a complex role in regulating the basal catalytic activity of the alpha subunit. (285 aa)
5F3.150Probable DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. (513 aa)
hH2AzHistone H2A.Z; Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activa [...] (143 aa)
hel-2RuvB-like helicase 2; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (481 aa)
B24N11.060Uncharacterized protein NCU11158. (275 aa)
kpr-4Probable kinetochore protein spc25; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. (259 aa)
vsp-3Vacuolar-sorting protein snf7; Required for the sorting and concentration of proteins resulting in the entry of these proteins into the invaginating vesicles of the multivesicular body (MVB). Also required for the proteolytic cleavage of the transcription factor pacc-1 in response to alkaline ambient pH (By similarity). (228 aa)
NCU02539DNA helicase; Belongs to the MCM family. (1013 aa)
NCU02587RNA polymerase II transcription factor B subunit 3. (362 aa)
stk-20Serine/threonine protein kinase-20. (602 aa)
NCU02932mRNA stability protein; Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway. (199 aa)
NCU02940Uncharacterized protein. (664 aa)
NCU01896Uncharacterized protein. (1009 aa)
NCU02683Uncharacterized protein. (738 aa)
NCU02687Activator 1 41 kDa subunit. (387 aa)
NCU02965Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (766 aa)
NCU03190Rec8. (763 aa)
NCU03207Ran GTPase activating protein 1. (419 aa)
NCU00949Uncharacterized protein. (3095 aa)
pme-1Protein phosphatase methylesterase 1; Demethylates proteins that have been reversibly carboxymethylated. Demethylates the phosphatase PP2A catalytic subunit (By similarity); Belongs to the AB hydrolase superfamily. (454 aa)
NCU02742Uncharacterized protein. (1283 aa)
NCU02496M-phase inducer phosphatase 3. (554 aa)
NCU02616WD-repeat containing protein slp1. (609 aa)
NCU00800Protein kinase domain-containing protein. (756 aa)
NCU02011Importin subunit beta-1. (876 aa)
pcnProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa)
cdc5Serine/threonine protein kinase. (1021 aa)
NCU09261DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (221 aa)
NCU02079Cyclin-dependent kinases regulatory subunit; Binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. (118 aa)
hda-2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (499 aa)
prd-4Serine/threonine-protein kinase chk2. (702 aa)
NCU09744Nuclear pore complex subunit. (353 aa)
eat-6Anaphase-promoting complex subunit Apc5. (813 aa)
NCU00517Cell cycle checkpoint protein RAD17. (944 aa)
NCU02776Cell division control protein; Belongs to the CDC6/cdc18 family. (691 aa)
ptk-2Serine/threonine protein kinase. (713 aa)
NCU03291Double-strand-break repair protein rad21. (658 aa)
NCU03137Nuclear elongation and deformation protein 1. (843 aa)
NCU03073CBFD_NFYB_HMF domain-containing protein. (397 aa)
myo-1Myosin-1; Type-I myosin implicated in the organization of the actin cytoskeleton. Required for proper actin cytoskeleton polarization. At the cell cortex, assembles in patch-like structures together with proteins from the actin-polymerizing machinery and promotes actin assembly. Functions as actin nucleation-promoting factor (NPF) for the Arp2/3 complex (By similarity); Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1235 aa)
NCU02114G1/S-specific cyclin Cln1; Belongs to the cyclin family. (416 aa)
ham-4FHA domain-containing protein. (797 aa)
NCU09814Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (941 aa)
drc-1DNA replication complex GINS protein psf1; The GINS complex plays an essential role in the initiation of DNA replication. (216 aa)
qde-3RecQ family helicase. (2330 aa)
NCU08604Uncharacterized protein. (1492 aa)
NCU02791Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. (1284 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (824 aa)
mus-59Serine/threonine-protein kinase. (1233 aa)
NCU02758G2/mitotic-specific cyclin-B; Belongs to the cyclin family. (515 aa)
NCU02828Condensin complex component cnd2. (904 aa)
NCU03246Tyrosine-protein phosphatase CDC14. (654 aa)
NCU06767Replication factor C subunit 1. (1086 aa)
NCU07870DNA polymerase. (1479 aa)
NCU05705Uncharacterized protein. (128 aa)
stk-5Serine/threonine-protein kinase hal4; Belongs to the protein kinase superfamily. (497 aa)
atrxATRX. (1869 aa)
NCU06216Nuclear condensin complex subunit 3. (1262 aa)
NCU06269FHA domain-containing protein. (790 aa)
prk-6Protein kinase. (492 aa)
NCU07655Uncharacterized protein. (622 aa)
NCU07991DUF292 domain-containing protein. (299 aa)
ppm-1-2Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. (431 aa)
NCU07998Uncharacterized protein. (441 aa)
NCU08009DNA helicase; Belongs to the MCM family. (944 aa)
NCU06988Spc97/Spc98 family protein. (1362 aa)
drc-2DNA replication complex GINS protein psf2; The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation (By similarity). (273 aa)
NCU06331Uncharacterized protein. (448 aa)
NCU08317PHD-type domain-containing protein. (1021 aa)
NCU07313Chromosome transmission fidelity protein 18. (997 aa)
NCU07321Uncharacterized protein. (272 aa)
NCU06611Uncharacterized protein. (515 aa)
NCU06623CBFD_NFYB_HMF domain-containing protein. (304 aa)
NCU07679Structural maintenance of chromosomes protein. (1179 aa)
kpr-2Probable kinetochore protein nuf2; Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity. (464 aa)
NCU05194DNA helicase; Belongs to the MCM family. (972 aa)
NCU05296Spindle pole body component. (895 aa)
rpa-2Replication protein A-2. (284 aa)
stk-44Serine/threonine protein kinase-44. (1267 aa)
NCU05280Uncharacterized protein. (487 aa)
NCU05282Spindle pole body component. (1042 aa)
NCU05250Sister chromatid cohesion protein. (1955 aa)
cao-1Carotenoid oxygenase 1. (526 aa)
NCU03825FCP1 homology domain-containing protein. (641 aa)
csaDNA excision repair protein. (1269 aa)
NCU01269Cell cycle regulatory protein. (611 aa)
NCU0384014_3_3 domain-containing protein. (314 aa)
NCU05513Uncharacterized protein. (618 aa)
NCU05536Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit. (1010 aa)
NCU04784Peptidase S59 domain-containing protein. (1844 aa)
NCU04738Zf-primase domain-containing protein. (977 aa)
NCU07078Uncharacterized protein. (326 aa)
NCU05781Mitotic spindle checkpoint component MAD2. (244 aa)
NCU05820Uncharacterized protein. (477 aa)
NCU06098Uncharacterized protein. (812 aa)
NCU06144Kinesin; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1289 aa)
NCU02232DNA primase; Belongs to the eukaryotic-type primase small subunit family. (576 aa)
jip5WD repeat-containing protein jip5. (421 aa)
NCU02411Uncharacterized protein. (1491 aa)
drc-3DNA replication complex GINS protein psf3; The GINS complex plays an essential role in the initiation of DNA replication. (218 aa)
NCU06894C3H1-type domain-containing protein. (602 aa)
NCU09038Protein kinase domain-containing protein. (644 aa)
NCU09706DNA ligase. (917 aa)
stk-12Serine threonine protein kinase. (1943 aa)
NCU09439RecQ mediated genome instability protein Rmi1. (284 aa)
NCU09062ELYS domain-containing protein. (299 aa)
NCU09063Nuclear condensin complex subunit Smc4. (1650 aa)
NCU07400CAP-Gly domain-containing protein. (872 aa)
NCU09297Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1249 aa)
NCU09500ATPase_AAA_core domain-containing protein. (1353 aa)
NCU09503Uncharacterized protein. (1048 aa)
NCU09855Nicotianamine synthase. (339 aa)
fwd-2F-box/WD-40 domain-containing protein 2. (755 aa)
NCU10155DNA polymerase epsilon subunit B. (851 aa)
NCU09422Uncharacterized protein. (302 aa)
NCU05907Uncharacterized protein. (129 aa)
NCU06942Vacuolar protein sorting-associated protein VPS4; Belongs to the AAA ATPase family. (441 aa)
NCU08903Nop10 family nucleolar RNA-binding protein. (67 aa)
NCU09982Cytoplasmic dynein 1 light intermediate chain. (550 aa)
NCU05972Sporulation-specific protein 6. (706 aa)
fiProtein serine/threonine kinase; Belongs to the protein kinase superfamily. (489 aa)
NCU07554Structural maintenance of chromosomes protein. (1204 aa)
NCU00243Microtubule-associated protein RP/EB family member 1. (248 aa)
NCU00273Uncharacterized protein. (1762 aa)
mdm34Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm34 is required for the interaction of the ER-resident membrane protein mmm-1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10. (615 aa)
NCU04007Uncharacterized protein. (1370 aa)
NCU04058BZIP domain-containing protein. (306 aa)
NCU04378DNA replication initiation factor Cdc45. (874 aa)
div-4Cell division protein kinase. (390 aa)
NCU04428Uncharacterized protein. (825 aa)
NCU04437Uncharacterized protein. (611 aa)
stk-42Serine/threonine protein kinase-42. (562 aa)
stk-13Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (420 aa)
NCU06481DNA ligase. (923 aa)
NCU04463Non-repetitive nucleoporin. (1441 aa)
NCU04513Ubiquitin conjugating enzyme Ubc14. (204 aa)
NCU04535Spindle pole body component. (944 aa)
PIF1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (931 aa)
NCU00435SNF7 family protein. (227 aa)
NCU00199Nup188_C domain-containing protein. (1858 aa)
NCU00205Peptidase C50 domain-containing protein. (2185 aa)
crf4-1Chromatin remodelling complex ATPase chain ISW1. (1126 aa)
NCU00081DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (695 aa)
stk-30Protein kinase. (757 aa)
hH4vHistone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (163 aa)
NCU01572WD domain-containing protein. (856 aa)
NCU00051Uncharacterized protein. (366 aa)
NCU04083Uncharacterized protein. (831 aa)
fwd-1F-box/WD-40 domain-containing protein 1. (977 aa)
NCU04548DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2259 aa)
NCU03860mRNA stability protein; Plays an essential role in initiation of the G0 program by preventing the degradation of specific nutrient-regulated mRNAs via the 5'-3' mRNA decay pathway. (167 aa)
NCU01304Mitochondrial mRNA processing protein PET127. (850 aa)
NCU01247SCD domain-containing protein. (1226 aa)
NCU01248Telo_bind domain-containing protein. (735 aa)
mdk-1Cyclin-dependent protein kinase; Belongs to the protein kinase superfamily. (337 aa)
NCU01702Nuclear pore protein. (1161 aa)
NCU00424Spo76 protein. (1595 aa)
ranGTP-binding nuclear protein GSP1/Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle (By similarity). (215 aa)
cdc28Cell division control protein 2; Belongs to the protein kinase superfamily. (328 aa)
cen-cCentromere protein C. (755 aa)
NCU037653'-5' exonuclease/helicase. (753 aa)
NCU03001Uncharacterized protein. (552 aa)
frManganese ion homeostasis protein. (756 aa)
NCU06776Uncharacterized protein. (632 aa)
NCU05459Mitochondrial AAA ATPase. (1104 aa)
NCU08427Activator 1 subunit 3. (389 aa)
NCU06851Uncharacterized protein. (938 aa)
NCU05433Uncharacterized protein. (412 aa)
NCU05385MutL_C domain-containing protein. (937 aa)
NCU01067CYCLIN domain-containing protein. (427 aa)
NCU01171DNA helicase; Belongs to the MCM family. (724 aa)
pold-1DNA polymerase. (1104 aa)
NCU03681Uncharacterized protein. (598 aa)
NCU03735Uncharacterized protein. (306 aa)
NCU01303Uncharacterized protein. (911 aa)
NCU01323Structural maintenance of chromosomes protein. (1263 aa)
NCU01340Uncharacterized protein. (215 aa)
NCU03597DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (667 aa)
rpa-1Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (610 aa)
NCU04131Uncharacterized protein. (597 aa)
NCU04153Pseudouridine synthase. (486 aa)
NCU04232Uncharacterized protein. (395 aa)
NCU03763DNA polymerase delta subunit 2. (525 aa)
naf-2Nucleosome assembly factor-2; Belongs to the nucleosome assembly protein (NAP) family. (328 aa)
NCU04302Ubiquitin-conjugating enzyme E; Belongs to the ubiquitin-conjugating enzyme family. (157 aa)
spo11Meiosis-specific topoisomerase Spo11. (466 aa)
NCU04319Spindle pole body component. (967 aa)
mrc1MRC1. (1464 aa)
stk-29Protein kinase. (1077 aa)
NCU04327DNA helicase; Belongs to the MCM family. (882 aa)
NCU01370Uncharacterized protein. (603 aa)
NCU01387Spindle pole body component. (922 aa)
NCU06644RanBD1 domain-containing protein. (1384 aa)
NCU01290Centromere/microtubule-binding protein CBF5. (480 aa)
prk-3Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (407 aa)
NCU08951H/ACA ribonucleoprotein complex subunit 2. (242 aa)
NCU04665Uncharacterized protein. (235 aa)
NCU09217Golgi reassembly stacking protein. (384 aa)
NCU04618Uncharacterized protein. (1110 aa)
NCU07146Uncharacterized protein. (1077 aa)
NCU07192Uncharacterized protein. (839 aa)
NCU07222Uncharacterized protein. (267 aa)
NCU01746Uncharacterized protein. (177 aa)
NCU03528DNA polymerase delta subunit 4. (241 aa)
NCU01824UDP-galactopyranose mutase. (517 aa)
NCU01791SNF7 family protein. (235 aa)
ro-3Dynactin, 150 kDa isoform; Required for the cytoplasmic dynein-driven retrograde movement of vesicles and organelles along microtubules. Dynein-dynactin interaction is a key component of the mechanism of axonal transport of vesicles and organelles (By similarity). (1367 aa)
tbgTubulin gamma chain; Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly. (461 aa)
pph-1Serine/threonine-protein phosphatase PP2A catalytic subunit. (327 aa)
nim-1G2-specific protein kinase nim-1; Protein kinase that plays an important role in mitotic regulation. (858 aa)
erg-3Delta(14)-sterol reductase; Reduces the C14=C15 double bond of 4,4-dimethyl-cholesta- 8,14,24-trienol to produce 4,4-dimethyl-cholesta-8,24-dienol; Belongs to the ERG4/ERG24 family. (490 aa)
tba-2Tubulin alpha-B chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (449 aa)
tba-1Tubulin alpha-A chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (454 aa)
hh2bHistone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (137 aa)
ypt-1GTP-binding protein ypt1; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Ypt-1 regulates the trafficking of secretory vesicles from the endoplasmic reticulum (ER) to the Golgi. Plays a role in the initial events of the autophagic vacuole development which take [...] (203 aa)
ubi::crp-6Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (154 aa)
ubiPolyubiquitin; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys [...] (305 aa)
tub-2Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
ro-11Nuclear distribution protein nudE homolog 1; Required for nuclear migration within hyphae during vegetative growth. (697 aa)
NCU01090Uncharacterized protein. (656 aa)
NCU01242G2/mitotic-specific cyclin; Belongs to the cyclin family. (653 aa)
cdc7Cell cycle protein kinase. (526 aa)
NCU10430SNF7 family protein. (215 aa)
NCU11331Protein kinase domain-containing protein. (427 aa)
NCU10467Replication factor C subunit 4. (357 aa)
dnr-8Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (394 aa)
msh4MutS ortholog 4 protein. (1318 aa)
mus-9Phosphatidyl inositol 3-kinase; Belongs to the PI3/PI4-kinase family. (2492 aa)
NCU00488Protein phosphatase PP2A regulatory subunit A. (635 aa)
rpa-3Replication protein A-3. (108 aa)
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A
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