STRINGSTRING
NCU04940 NCU04940 NCU02458 NCU02458 NCU06080 NCU06080 NCU08169 NCU08169 NCU02358 NCU02358 pbd-1 pbd-1 NCU06061 NCU06061 NCU05888 NCU05888 NCU05887 NCU05887 NCU05850 NCU05850 NCU02307 NCU02307 mss4 mss4 NCU02293 NCU02293 bdp-2 bdp-2 set-5 set-5 NCU07061 NCU07061 hat-6 hat-6 NCU04766 NCU04766 NCU07071 NCU07071 NCU05536 NCU05536 NCU05523 NCU05523 NCU05608 NCU05608 NCU03840 NCU03840 trf-2 trf-2 epl-1 epl-1 NCU03589 NCU03589 crf7-1 crf7-1 NCU06636 NCU06636 NCU04320 NCU04320 NCU07893 NCU07893 NCU05257 NCU05257 hda-4 hda-4 stk-44 stk-44 NCU08658 NCU08658 NCU05305 NCU05305 NCU05300 NCU05300 pgi-1 pgi-1 NCU05191 NCU05191 NCU07672 NCU07672 NCU06607 NCU06607 NCU07327 NCU07327 NCU06303 NCU06303 NCU06993 NCU06993 NCU08047 NCU08047 NCU08030 NCU08030 NCU08006 NCU08006 NCU08003 NCU08003 NCU08527 NCU08527 NCU08525 NCU08525 stk-5 stk-5 NCU08553 NCU08553 NCU08543 NCU08543 NCU08542 NCU08542 NCU06233 NCU06233 NCU07854 NCU07854 NCU08416 NCU08416 NCU08735 NCU08735 NCU02086 NCU02086 NCU00806 NCU00806 NCU09388 NCU09388 NCU09382 NCU09382 NCU09378 NCU09378 NCU03047 NCU03047 NCU09307 NCU09307 qde-3 qde-3 NCU03037 NCU03037 NCU02103 NCU02103 NCU03151 NCU03151 NCU03132 NCU03132 eaf6 eaf6 ptk-2 ptk-2 NCU01969 NCU01969 NCU00730 NCU00730 prd-4 prd-4 NCU02162 NCU02162 cen-T cen-T NCU03177 NCU03177 NCU03158 NCU03158 NCU02078 NCU02078 NCU02077 NCU02077 NCU02066 NCU02066 NCU02043 NCU02043 NCU09259 NCU09259 cdc5 cdc5 soh1 soh1 NCU00941 NCU00941 NCU08634 NCU08634 NCU02605 NCU02605 NCU02594 NCU02594 NCU07509 NCU07509 NCU07508 NCU07508 set-7 set-7 NCU02496 NCU02496 NCU02719 NCU02719 NCU00973 NCU00973 NCU08347 NCU08347 NCU03191 NCU03191 NCU03033 NCU03033 NCU02661 NCU02661 stk-20 stk-20 NCU02587 NCU02587 NCU02563 NCU02563 arp-4 arp-4 NCU02550 NCU02550 MED17 MED17 prk-11 prk-11 NCU11012 NCU11012 mus-9 mus-9 NCU10232 NCU10232 NCU11241 NCU11241 NCU11252 NCU11252 NCU10270 NCU10270 NCU11325 NCU11325 NCU11331 NCU11331 NCU10169 NCU10169 NCU06556 NCU06556 NCU04287 NCU04287 NCU01090 NCU01090 ssp-1 ssp-1 cox-2 cox-2 cox-3 cox-3 cox-1 cox-1 cox-4 cox-4 cya-4 cya-4 ubi ubi ubi::crp-6 ubi::crp-6 hh2b hh2b nit-6 nit-6 cox-6 cox-6 cr-1 cr-1 stk-23 stk-23 NCU08768 NCU08768 NCU01580 NCU01580 NCU01571 NCU01571 NCU01657 NCU01657 cox-15 cox-15 NCU01802 NCU01802 NCU01831 NCU01831 NCU03416 NCU03416 stk-1 stk-1 gtr-1 gtr-1 ckb-2 ckb-2 ckb-1 ckb-1 cka cka set-1 set-1 rtf-1 rtf-1 ctc-2 ctc-2 ssn8 ssn8 med-6 med-6 tcf-29 tcf-29 tsp-2 tsp-2 aab-1 aab-1 NCU00144 NCU00144 NCU00370 NCU00370 NCU00221 NCU00221 NCU16699 NCU16699 NCU17260 NCU17260 NCU10015 NCU10015 NCU17268 NCU17268 NCU06930 NCU06930 NCU03855 NCU03855 NCU03782 NCU03782 NCU09300 NCU09300 NCU12058 NCU12058 NCU17251 NCU17251 NCU05883 NCU05883 mek-2 mek-2 NCU08331 NCU08331 stk-47 stk-47 NCU07042 NCU07042 NCU03406 NCU03406 NCU04808 NCU04808 NCU10346 NCU10346 stk-46 stk-46 NCU16549 NCU16549 NCU04105 NCU04105 stk-8 stk-8 un-1 un-1 NCU03337 NCU03337 NCU03219 NCU03219 NCU11372 NCU11372 NCU09248 NCU09248 os-5 os-5 NCU16461 NCU16461 NCU02941 NCU02941 NCU02796 NCU02796 NCU02547 NCU02547 NCU16550 NCU16550 NCU02121 NCU02121 eat-5 eat-5 NCU02957 NCU02957 NCU02578 NCU02578 nfh-1 nfh-1 NCU03799 NCU03799 NCU04278 NCU04278 NCU04281 NCU04281 NCU04307 NCU04307 NCU06719 NCU06719 prk-3 prk-3 NCU01419 NCU01419 NCU01764 NCU01764 NCU01515 NCU01515 NCU07808 NCU07808 NCU07412 NCU07412 NCU09503 NCU09503 nde-3 nde-3 NCU09439 NCU09439 NCU09899 NCU09899 NCU09877 NCU09877 med-7 med-7 NCU05943 NCU05943 NCU09001 NCU09001 NCU08996 NCU08996 NCU08985 NCU08985 trf-3 trf-3 NCU06920 NCU06920 NCU06919 NCU06919 NCU06913 NCU06913 NCU06889 NCU06889 pbn1 pbn1 bek-1 bek-1 NCU06438 NCU06438 stk-42 stk-42 mek-1 mek-1 div-4 div-4 set-4 set-4 NCU06880 NCU06880 NCU04073 NCU04073 NCU04058 NCU04058 yaf9 yaf9 mdm34 mdm34 NCU00324 NCU00324 NCU09449 NCU09449 mig-6 mig-6 NCU09755 NCU09755 rgr1 rgr1 NCU06484 NCU06484 crf3-1 crf3-1 NCU05120 NCU05120 NCU04492 NCU04492 NCU04495 NCU04495 NCU04496 NCU04496 NCU00017 NCU00017 NCU04508 NCU04508 snf5 snf5 nut2 nut2 gh6-1 gh6-1 NCU01625 NCU01625 NCU05064 NCU05064 NCU00070 NCU00070 NCU00081 NCU00081 stk-30 stk-30 NCU01542 NCU01542 ctc-1 ctc-1 NCU00045 NCU00045 NCU04363 NCU04363 NCU08757 NCU08757 NCU03461 NCU03461 NCU03572 NCU03572 nfh-2 nfh-2 NCU09111 NCU09111 NCU03765 NCU03765 B5K2.060 B5K2.060 oxa-2 oxa-2 NCU06789 NCU06789 NCU06838 NCU06838 cox-13 cox-13 NCU05340 NCU05340 sre sre NCU01067 NCU01067 NCU01209 NCU01209 NCU03714 NCU03714 NCU03728 NCU03728 NCU01319 NCU01319 rpa-1 rpa-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCU04940Reticulon-4-interacting protein 1. (347 aa)
NCU02458Uncharacterized protein. (259 aa)
NCU06080PKS_ER domain-containing protein. (355 aa)
NCU08169Uncharacterized protein. (208 aa)
NCU02358SDS23; Involved in DNA replication and cell separation. Belongs to the SDS23 family. (542 aa)
pbd-1RSC complex subunit. (1206 aa)
NCU06061Oxidoreductase. (433 aa)
NCU05888Dibenzothiophene desulfurization enzyme A. (485 aa)
NCU05887Oxidoreductase. (461 aa)
NCU05850Rubredoxin-NAD(+) reductase. (611 aa)
NCU02307Zn(2)-C6 fungal-type domain-containing protein. (743 aa)
mss4Phosphatidylinositol-4-phosphate 5-kinase its3. (1012 aa)
NCU02293Uncharacterized protein. (117 aa)
bdp-2Transcriptional activator spt7. (1172 aa)
set-5SET-5. (309 aa)
NCU07061Uncharacterized protein. (177 aa)
hat-6Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (1188 aa)
NCU04766Ccr4-Not transcription complex subunit. (2098 aa)
NCU07071Cell differentiation protein rcd1. (356 aa)
NCU05536Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit. (1010 aa)
NCU05523RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (501 aa)
NCU05608Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2443 aa)
NCU0384014_3_3 domain-containing protein. (314 aa)
trf-2Transcription elongation factor spt4; The spt4-spt5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity). (120 aa)
epl-1Enhancer of polycomb-like protein 1; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Involved in gene silencing by neighboring heterochromatin, blockage of the silencing spreading along the chromosome, and required for cell cycle progression through G2/M (By similarity). (589 aa)
NCU03589Uncharacterized protein. (227 aa)
crf7-1Chromodomain-helicase-DNA-binding protein 4. (1726 aa)
NCU06636Cell division control protein 14. (287 aa)
NCU04320Transcriptional co-activator. (457 aa)
NCU07893RSC complex subunit Sfh1. (591 aa)
NCU05257Homeobox and C2H2 transcription factor. (1321 aa)
hda-4Histone deacetylase HosB. (1212 aa)
stk-44Serine/threonine protein kinase-44. (1267 aa)
NCU08658C6 zinc finger domain-containing protein. (1120 aa)
NCU05305DNA-directed RNA polymerase II polypeptide. (234 aa)
NCU05300WD_REPEATS_REGION domain-containing protein. (685 aa)
pgi-1Glucose-6-phosphate isomerase. (561 aa)
NCU05191Uncharacterized protein. (306 aa)
NCU07672CUE domain-containing protein. (222 aa)
NCU06607Uncharacterized protein. (572 aa)
NCU07327Uncharacterized protein. (173 aa)
NCU06303Alcohol dehydrogenase. (375 aa)
NCU06993Ash2-trithorax family protein. (581 aa)
NCU08047Uncharacterized protein. (784 aa)
NCU08030DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (152 aa)
NCU08006Uncharacterized protein. (727 aa)
NCU08003RSC complex subunit. (690 aa)
NCU08527Zn(2)-C6 fungal-type domain-containing protein. (554 aa)
NCU08525Myb-like domain-containing protein. (658 aa)
stk-5Serine/threonine-protein kinase hal4; Belongs to the protein kinase superfamily. (497 aa)
NCU08553DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (130 aa)
NCU08543Uncharacterized protein. (706 aa)
NCU08542Uncharacterized protein. (552 aa)
NCU06233PHD domain-containing protein. (843 aa)
NCU07854Cytosolic regulator Pianissimo. (1547 aa)
NCU08416DUF1674 domain-containing protein. (169 aa)
NCU08735Uncharacterized protein. (545 aa)
NCU02086Uncharacterized protein. (562 aa)
NCU00806Uncharacterized protein. (238 aa)
NCU09388PHD domain-containing protein. (789 aa)
NCU09382TPR domain-containing protein. (386 aa)
NCU09378DNA-directed RNA polymerase II polypeptide. (146 aa)
NCU03047Uncharacterized protein. (345 aa)
NCU09307Uncharacterized protein. (1094 aa)
qde-3RecQ family helicase. (2330 aa)
NCU03037Uncharacterized protein. (200 aa)
NCU02103DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1761 aa)
NCU03151Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (166 aa)
NCU03132Uncharacterized protein. (731 aa)
eaf6Chromatin modification-related protein eaf6; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (187 aa)
ptk-2Serine/threonine protein kinase. (713 aa)
NCU01969Thioredoxin domain-containing protein. (198 aa)
NCU00730Fungal_trans domain-containing protein. (904 aa)
prd-4Serine/threonine-protein kinase chk2. (702 aa)
NCU02162SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (340 aa)
cen-TCEN-T. (599 aa)
NCU03177Sco1. (282 aa)
NCU03158Alpha/beta hydrolase. (421 aa)
NCU02078Uncharacterized protein. (713 aa)
NCU02077Uncharacterized protein. (1009 aa)
NCU02066Ribosome assembly protein Noc2. (790 aa)
NCU02043UPF0326 protein hag1. (312 aa)
NCU09259Uncharacterized protein. (625 aa)
cdc5Serine/threonine protein kinase. (1021 aa)
soh1Mediator of RNA polymerase II transcription subunit 31; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (134 aa)
NCU00941Uncharacterized protein. (1048 aa)
NCU08634Fork-head domain-containing protein. (540 aa)
NCU02605DNA-directed RNA polymerase I/II/III subunit 10. (84 aa)
NCU02594Uncharacterized protein. (1197 aa)
NCU07509Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX. (350 aa)
NCU07508Uncharacterized protein. (540 aa)
set-7SET-7. (1611 aa)
NCU02496M-phase inducer phosphatase 3. (554 aa)
NCU02719BHLH domain-containing protein. (136 aa)
NCU00973PKS_ER domain-containing protein. (419 aa)
NCU08347SprT-like domain-containing protein. (457 aa)
NCU03191Rab proteins geranylgeranyltransferase; Belongs to the Rab GDI family. (490 aa)
NCU03033CCAAT-binding complex subunit HAP2. (314 aa)
NCU02661DNA-directed RNA polymerase II polypeptide. (171 aa)
stk-20Serine/threonine protein kinase-20. (602 aa)
NCU02587RNA polymerase II transcription factor B subunit 3. (362 aa)
NCU02563Transcription elongation factor S-II. (298 aa)
arp-4Actin-related protein 4; Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosome [...] (469 aa)
NCU02550Alpha-galactosidase. (874 aa)
MED17Mediator of RNA polymerase II transcription subunit 17; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (679 aa)
prk-11Serine/threonine-protein kinase BUD32. (299 aa)
NCU11012DNA-directed RNA polymerase I. (160 aa)
mus-9Phosphatidyl inositol 3-kinase; Belongs to the PI3/PI4-kinase family. (2492 aa)
NCU10232Uncharacterized protein. (557 aa)
NCU11241Nuclease domain-containing protein. (379 aa)
NCU11252Cyclin Pch1; Belongs to the cyclin family. (547 aa)
NCU10270Uncharacterized protein. (290 aa)
NCU11325Alcohol dehydrogenase. (337 aa)
NCU11331Protein kinase domain-containing protein. (427 aa)
NCU10169Uncharacterized protein. (240 aa)
NCU06556Thioredoxin II. (147 aa)
NCU04287Uncharacterized protein. (227 aa)
NCU01090Uncharacterized protein. (656 aa)
ssp-1Peptidyl-prolyl cis-trans isomerase ssp-1; Site-specific PPIase with respect to the amino acid N- terminal to the proline residue. Peptides with glutamate, phosphoserine, or phosphothreonine in the -1 position are the best substrates. It is not only able to isomerize small peptides but is also active in protein folding. (182 aa)
cox-2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (250 aa)
cox-3Cytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (269 aa)
cox-1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (557 aa)
cox-4Cytochrome c oxidase subunit 4, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (186 aa)
cya-4Cytochrome c oxidase subunit 5, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (171 aa)
ubiPolyubiquitin; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys [...] (305 aa)
ubi::crp-6Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (154 aa)
hh2bHistone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (137 aa)
nit-6Nitrite reductase [NAD(P)H]. (1176 aa)
cox-6Cytochrome c oxidase subunit 6, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (148 aa)
cr-1Adenylate cyclase; Plays essential roles in regulation of cellular metabolism by catalyzing the synthesis of a second messenger, cAMP. (2300 aa)
stk-23Serine/threonine protein kinase. (921 aa)
NCU08768PKS_ER domain-containing protein. (407 aa)
NCU01580Transcription factor TFIIH subunit Tfb4. (439 aa)
NCU01571Uncharacterized protein. (419 aa)
NCU01657Cytochrome-c oxidase assembly protein. (315 aa)
cox-15Cytochrome c oxidase subunit 8, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (82 aa)
NCU01802Uncharacterized protein. (563 aa)
NCU01831General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (469 aa)
NCU03416Telomeric repeat binding factor 1. (1149 aa)
stk-1Serine/threonine-protein kinase bur1; Serine/threonine-protein kinase involved in transcription regulation. Phosphorylates the mus-8/ubc2 ubiquitin-conjugating enzyme (E2), leading to monoubiquitination of histone H2B and the silencing of telomeric-associated genes. Also required for histone H3 methylation. Necessary for the recovery from pheromone-induced growth arrest in the cell cycle G1 phase (By similarity). (559 aa)
gtr-1Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. (468 aa)
ckb-2Casein kinase II subunit beta-2; Plays a complex role in regulating the basal catalytic activity of the alpha subunit. (285 aa)
ckb-1Casein kinase II subunit beta-1; Plays a complex role in regulating the basal catalytic activity of the alpha subunit. (333 aa)
ckaCasein kinase II subunit alpha; Phosphorylates the frq clock protein thus regulating the circadian clock; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. CK2 subfamily. (336 aa)
set-1Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance and transcription elongation regulation. Belongs to the class V-like SAM-binding methyltransferase superfamily. (1313 aa)
rtf-1General transcription and DNA repair factor IIH subunit rtf-1; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has b [...] (72 aa)
ctc-2FACT complex subunit ctc-2; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (1032 aa)
ssn8RNA polymerase II holoenzyme cyclin-like subunit; Component of the srb8-11 complex. The srb8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex. The srb8-11 complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II (By s [...] (345 aa)
med-6Mediator of RNA polymerase II transcription subunit 6; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (360 aa)
tcf-29General transcription and DNA repair factor IIH subunit tcf-29; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has [...] (663 aa)
tsp-2Probable tRNA-splicing endonuclease subunit tsp-2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant [...] (633 aa)
aab-1CCAAT-binding transcription factor subunit AAB-1, variant 1. (271 aa)
NCU00144BHLH domain-containing protein. (494 aa)
NCU00370Uncharacterized protein. (350 aa)
NCU00221Uncharacterized protein. (775 aa)
NCU16699PIPK domain-containing protein. (401 aa)
NCU17260Uncharacterized protein. (455 aa)
NCU10015Methanesulfonate monooxygenase. (400 aa)
NCU17268Uncharacterized protein. (286 aa)
NCU06930Uncharacterized protein. (2202 aa)
NCU03855CCR4-NOT transcription complex, variant. (640 aa)
NCU03782DNA-directed RNA polymerase II subunit RPB11. (133 aa)
NCU09300RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II. (868 aa)
NCU12058Oxidoreductase. (446 aa)
NCU17251Uncharacterized protein. (83 aa)
NCU05883Xenobiotic compound monooxygenase. (481 aa)
mek-2Mitogen activated protein kinase kinase 2. (511 aa)
NCU08331Uncharacterized protein. (1008 aa)
stk-47Protein kinase. (1250 aa)
NCU07042Alcohol dehydrogenase. (368 aa)
NCU03406Skp1_POZ domain-containing protein; Belongs to the SKP1 family. (109 aa)
NCU04808Uncharacterized protein. (914 aa)
NCU10346Uncharacterized protein. (2592 aa)
stk-46Serine/threonine protein kinase. (1405 aa)
NCU16549Thermatolerance membrane protein Dlt1. (687 aa)
NCU04105Rap-GAP domain-containing protein. (1655 aa)
stk-8Serine/threonine-protein kinase prk1. (557 aa)
un-1Serine/threonine protein kinase. (620 aa)
NCU03337ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (483 aa)
NCU03219Kex2, variant 1. (884 aa)
NCU11372NOT2_3_5 domain-containing protein. (485 aa)
NCU09248CCAAT-binding protein subunit HAP3. (201 aa)
os-5Mitogen activated protein kinase kinase, variant. (683 aa)
NCU16461Uncharacterized protein. (170 aa)
NCU02941Uncharacterized protein. (226 aa)
NCU02796Chromatin modification-related protein. (663 aa)
NCU02547Thioredoxin-like_fold domain-containing protein. (276 aa)
NCU16550Uncharacterized protein. (945 aa)
NCU02121Transcriptional regulator. (633 aa)
eat-5Cytochrome c oxidase subunit 13, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (136 aa)
NCU02957BHLH domain-containing protein. (486 aa)
NCU02578Paired amphipathic helix protein Sin3a, variant. (1490 aa)
nfh-1DNA damage checkpoint protein rad24, variant; Belongs to the 14-3-3 family. (224 aa)
NCU03799Pre-mRNA splicing factor prp45. (569 aa)
NCU04278Uncharacterized protein. (761 aa)
NCU04281WD-repeat protein pop3. (318 aa)
NCU04307MSF1. (198 aa)
NCU06719MSF1 domain-containing protein. (235 aa)
prk-3Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (407 aa)
NCU01419Quinone oxidoreductase. (338 aa)
NCU01764Uncharacterized protein. (229 aa)
NCU01515DNA-directed RNA polymerase II polypeptide. (337 aa)
NCU07808ABM domain-containing protein. (106 aa)
NCU07412PHD finger and BAH domain-containing protein. (1842 aa)
NCU09503Uncharacterized protein. (1048 aa)
nde-3NAD(P)H dehydrogenase 3. (485 aa)
NCU09439RecQ mediated genome instability protein Rmi1. (284 aa)
NCU09899Frp1. (516 aa)
NCU09877Uncharacterized protein. (424 aa)
med-7Mediator of RNA polymerase II transcription subunit 7; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (347 aa)
NCU05943TFIIS central domain-containing protein. (1050 aa)
NCU09001CCR4-NOT transcription complex subunit 7. (572 aa)
NCU08996Uncharacterized protein. (149 aa)
NCU08985Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (214 aa)
trf-3Transcription elongation factor spt5; The spt4-spt5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity). (1054 aa)
NCU06920Uncharacterized protein. (273 aa)
NCU06919Uncharacterized protein. (274 aa)
NCU06913Uncharacterized protein. (530 aa)
NCU06889Uncharacterized protein. (532 aa)
pbn1Protein pbn1; Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase gim- 1/gpi14 (By similarity). (501 aa)
bek-1BEAK-1. (267 aa)
NCU06438DNA repair helicase RAD25. (862 aa)
stk-42Serine/threonine protein kinase-42. (562 aa)
mek-1MAP kinase kinase. (518 aa)
div-4Cell division protein kinase. (390 aa)
set-4SET-4. (948 aa)
NCU06880Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (196 aa)
NCU04073Uncharacterized protein. (1618 aa)
NCU04058BZIP domain-containing protein. (306 aa)
yaf9Protein AF-9 homolog; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised (By similarity). (309 aa)
mdm34Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm34 is required for the interaction of the ER-resident membrane protein mmm-1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10. (615 aa)
NCU00324Uncharacterized protein. (823 aa)
NCU09449mRNA_triPase domain-containing protein. (1059 aa)
mig-6Zinc-containing alcohol dehydrogenase. (346 aa)
NCU09755Uncharacterized protein. (411 aa)
rgr1Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (1274 aa)
NCU06484Uncharacterized protein. (1955 aa)
crf3-1SNF2-family ATP dependent chromatin remodeling factor snf21. (1482 aa)
NCU05120DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1287 aa)
NCU04492Uncharacterized protein. (294 aa)
NCU04495C-type cyclin. (442 aa)
NCU04496Phytocyanin domain-containing protein. (221 aa)
NCU00017Zn(2)-C6 fungal-type domain-containing protein. (809 aa)
NCU04508Uncharacterized protein. (75 aa)
snf5SWI-SNF complex subunit. (732 aa)
nut2Mediator of RNA polymerase II transcription subunit 10; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity). (253 aa)
gh6-1Glucanase; Belongs to the glycosyl hydrolase family 6. (396 aa)
NCU01625DNA repair helicase RAD3. (806 aa)
NCU05064C2H2 transcription factor. (785 aa)
NCU00070PHD-type domain-containing protein. (888 aa)
NCU00081DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (695 aa)
stk-30Protein kinase. (757 aa)
NCU01542Uncharacterized protein. (1396 aa)
ctc-1FACT complex subunit ctc-1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (565 aa)
NCU00045PHD finger domain-containing protein. (1261 aa)
NCU04363Uncharacterized protein. (690 aa)
NCU08757PKS_ER domain-containing protein. (503 aa)
NCU03461Chromatin modification-related protein. (824 aa)
NCU03572SWI-SNF complex subunit. (570 aa)
nfh-214-3-3 family protein 7; Belongs to the 14-3-3 family. (262 aa)
NCU09111Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (506 aa)
NCU037653'-5' exonuclease/helicase. (753 aa)
B5K2.060FAS1 domain-containing protein NCU02579. (228 aa)
oxa-2OXA-2. (441 aa)
NCU06789Uncharacterized protein. (185 aa)
NCU06838Uncharacterized protein. (648 aa)
cox-13Cytochrome c oxidase subunit 12, mitochondrial; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane [...] (84 aa)
NCU05340Alkanesulfonate monooxygenase. (377 aa)
sreGATA-type transcription factor sre; GATA-type transcription repressor that regulates iron- acquisition genes through specific binding the GATA sequence elements of target promoters in a zinc-dependent manner. Iron acquisition regulation is critical for survival under both iron-limiting conditions (to acquire essential iron) and iron-replete conditions (to limit iron toxicity). Represses the synthesis of siderophores in high iron conditions. (587 aa)
NCU01067CYCLIN domain-containing protein. (427 aa)
NCU01209Zn(2)-C6 fungal-type domain-containing protein. (520 aa)
NCU03714Thioredoxin. (580 aa)
NCU03728Zn(2)-C6 fungal-type domain-containing protein. (764 aa)
NCU01319Uncharacterized protein. (634 aa)
rpa-1Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (610 aa)
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A
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