STRINGSTRING
NCU07808 NCU07808 NCU09303 NCU09303 NCU09957 NCU09957 asf-1 asf-1 NCU08996 NCU08996 NCU06066 NCU06066 NCU06049 NCU06049 set-5 set-5 NCU08812 NCU08812 NCU05300 NCU05300 esa-1 esa-1 NCU08416 NCU08416 NCU01969 NCU01969 eat-6 eat-6 set-7 set-7 mus-23 mus-23 mak-2 mak-2 NCU11000 NCU11000 NCU17260 NCU17260 mek-2 mek-2 rcm-1 rcm-1 os-5 os-5 NCU08345 NCU08345 NCU02990 NCU02990 NCU06556 NCU06556 ubi ubi ubi::crp-6 ubi::crp-6 hh2b hh2b mak-1 mak-1 NCU01248 NCU01248 nrc-1 nrc-1 uvs-6 uvs-6 NCU04513 NCU04513 mek-1 mek-1 NCU04058 NCU04058 hir-1 hir-1 mus-21 mus-21 crf1-1 crf1-1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NCU07808ABM domain-containing protein. (106 aa)
NCU09303Uncharacterized protein. (459 aa)
NCU09957ANK_REP_REGION domain-containing protein. (986 aa)
asf-1Histone chaperone asf-1; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. (271 aa)
NCU08996Uncharacterized protein. (149 aa)
NCU0606637S ribosomal protein mrp10, mitochondrial; Involved in mitochondrial genome encoded proteins translation. (90 aa)
NCU06049DNA damage response protein RcaA. (912 aa)
set-5SET-5. (309 aa)
NCU08812Uncharacterized protein. (635 aa)
NCU05300WD_REPEATS_REGION domain-containing protein. (685 aa)
esa-1Histone acetyltransferase esa-1; Catalytic component of the NuA4 histone acetyltransferase (HAT) complex which is involved in epigenetic transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4, H3, H2B, H2A and H2A variant H2A.Z. Acetylates histone H4 to form H4K5ac, H4K8ac, H4K12ac and H4K16ac, histone H3 to form H3K14ac, histone H2B to form H2BK16ac, and histone H2A to form H2AK4ac and H2AK7ac. Acetylation of histone H4 is essential for DNA double- strand break repair through homologous recombination. Involved in cell cycle progression. Recr [...] (506 aa)
NCU08416DUF1674 domain-containing protein. (169 aa)
NCU01969Thioredoxin domain-containing protein. (198 aa)
eat-6Anaphase-promoting complex subunit Apc5. (813 aa)
set-7SET-7. (1611 aa)
mus-23Double-strand break repair protein mus-23; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing (By similarity); Belongs to the MRE11/RAD32 family. (739 aa)
mak-2Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (352 aa)
NCU11000HUN domain-containing protein. (684 aa)
NCU17260Uncharacterized protein. (455 aa)
mek-2Mitogen activated protein kinase kinase 2. (511 aa)
rcm-1RCM-1, variant. (917 aa)
os-5Mitogen activated protein kinase kinase, variant. (683 aa)
NCU08345Ubiquitin-conjugating enzyme E; Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
NCU02990Uncharacterized protein. (637 aa)
NCU06556Thioredoxin II. (147 aa)
ubiPolyubiquitin; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys [...] (305 aa)
ubi::crp-6Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (154 aa)
hh2bHistone H2B; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (137 aa)
mak-1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (413 aa)
NCU01248Telo_bind domain-containing protein. (735 aa)
nrc-1MAPKK kinase. (914 aa)
uvs-6UVS6. (1314 aa)
NCU04513Ubiquitin conjugating enzyme Ubc14. (204 aa)
mek-1MAP kinase kinase. (518 aa)
NCU04058BZIP domain-containing protein. (306 aa)
hir-1Protein hir-1; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1035 aa)
mus-21Serine/threonine-protein kinase tel1; Serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]- Q. Phosphorylates histone H2A to form H2AS128ph (gamma-H2A) at sites of DNA damage, involved in the regulation of DNA damage response mechanism. Required for the control of telomere length and genome stability (By similarity). (2939 aa)
crf1-1Helicase swr-1; Catalytic component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling; Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily. (1845 aa)
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A
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