STRINGSTRING
mus-44 mus-44 rpa-3 rpa-3 ubi ubi ubi::crp-6 ubi::crp-6 NCU01824 NCU01824 NCU03528 NCU03528 rpa-1 rpa-1 mus-38 mus-38 NCU00185 NCU00185 NCU04058 NCU04058 cul-4 cul-4 NCU05907 NCU05907 NCU09855 NCU09855 NCU09500 NCU09500 NCU09302 NCU09302 rad23 rad23 NCU05820 NCU05820 NCU09871 NCU09871 csn-3 csn-3 parp parp csn-6 csn-6 NCU06395 NCU06395 arp-5 arp-5 NCU06623 NCU06623 dim-8 dim-8 NCU07998 NCU07998 arp-8 arp-8 mus-40 mus-40 csn-7a csn-7a csn-2 csn-2 crf2-1 crf2-1 hel-1 hel-1 NCU16653 NCU16653 NCU16705 NCU16705 NCU02457 NCU02457 NCU09860 NCU09860 NCU04212 NCU04212 NCU16387 NCU16387
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mus-44Mating-type switching protein swi10. (405 aa)
rpa-3Replication protein A-3. (108 aa)
ubiPolyubiquitin; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be involved in DNA repair; Lys [...] (305 aa)
ubi::crp-6Ubiquitin-40S ribosomal protein S27a; Ubiquitin exists either covalently attached to another protein, or free (unanchored). When covalently bound, it is conjugated to target proteins via an isopeptide bond either as a monomer (monoubiquitin), a polymer linked via different Lys residues of the ubiquitin (polyubiquitin chains) or a linear polymer linked via the initiator Met of the ubiquitin (linear polyubiquitin chains). Polyubiquitin chains, when attached to a target protein, have different functions depending on the Lys residue of the ubiquitin that is linked: Lys-6-linked may be invo [...] (154 aa)
NCU01824UDP-galactopyranose mutase. (517 aa)
NCU03528DNA polymerase delta subunit 4. (241 aa)
rpa-1Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (610 aa)
mus-38MUS38. (960 aa)
NCU00185BRCT domain-containing protein. (382 aa)
NCU04058BZIP domain-containing protein. (306 aa)
cul-4Ubiquitin ligase subunit CulD; Belongs to the cullin family. (1039 aa)
NCU05907Uncharacterized protein. (129 aa)
NCU09855Nicotianamine synthase. (339 aa)
NCU09500ATPase_AAA_core domain-containing protein. (1353 aa)
NCU09302DNA damage-binding protein cmr1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes. (521 aa)
rad23Rad23-like protein. (383 aa)
NCU05820Uncharacterized protein. (477 aa)
NCU09871Centrin 3. (178 aa)
csn-3COP9 signalosome complex subunit 3; Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin- protein ligase complexes (By similarity). The CSN complex is involved in the regulation of the circadian clock through its control of the stability of the SCF(FWD1) complex. (497 aa)
parpPoly [ADP-ribose] polymerase. (670 aa)
csn-6COP9 signalosome complex subunit 6; Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin- protein ligase complexes (By similarity). The CSN complex is involved in the regulation of the circadian clock through its control of the stability of the SCF(FWD1) complex. (497 aa)
NCU06395YL1_C domain-containing protein. (210 aa)
arp-5Chromatin remodeling complex subunit; Belongs to the actin family. (762 aa)
NCU06623CBFD_NFYB_HMF domain-containing protein. (304 aa)
dim-8DNA damage-binding protein 1. (1158 aa)
NCU07998Uncharacterized protein. (441 aa)
arp-8Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family. (748 aa)
mus-40DNA excision repair protein Rad2. (1269 aa)
csn-7aCOP9 signalosome complex subunit 7a; Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin- protein ligase complexes (By similarity). The CSN complex is involved in the regulation of the circadian clock through its control of the stability of the SCF(FWD1) complex. (417 aa)
csn-2COP9 signalosome complex subunit 2; Component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin- protein ligase complexes (By similarity). The CSN complex is involved in the regulation of the circadian clock through its control of the stability of the SCF(FWD-1) complex. (490 aa)
crf2-1Chromatin-remodeling ATPase INO80; ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair. (1997 aa)
hel-1RuvB-like helicase 1; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant H2A.Z leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (458 aa)
NCU16653Uncharacterized protein. (210 aa)
NCU16705Chromo domain-containing protein. (145 aa)
NCU02457DNA-directed polymerase kappa, variant. (646 aa)
NCU09860Telomere silencing protein Zds1, variant. (870 aa)
NCU04212Uncharacterized protein. (511 aa)
NCU16387XPGI domain-containing protein. (226 aa)
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A
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