46 items (Neurospora crassa) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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gene fusions

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protein homology

Your Input:
	NCU05120	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1287 aa)
	NCU08553	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (130 aa)
	NCU08560	Acyl_transf_3 domain-containing protein. (481 aa)
	NCU08030	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (152 aa)
	NCU05305	DNA-directed RNA polymerase II polypeptide. (234 aa)
	NCU05523	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (501 aa)
	NCU02223	TFIID_20kDa domain-containing protein. (836 aa)
	NCU06889	Uncharacterized protein. (532 aa)
	NCU07757	Transcription initiation factor TFIID complex 60 kDa subunit. (465 aa)
	NCU04984	Uncharacterized protein. (339 aa)
	NCU06438	DNA repair helicase RAD25. (862 aa)
	NCU04508	Uncharacterized protein. (75 aa)
	NCU00448	DUF4211 domain-containing protein. (726 aa)
	NCU01625	DNA repair helicase RAD3. (806 aa)
	NCU04363	Uncharacterized protein. (690 aa)
	NCU04770	TATA-binding protein. (257 aa)
	NCU01067	CYCLIN domain-containing protein. (427 aa)
	NCU01322	Transcription factor TFIIE complex alpha subunit. (353 aa)
	NCU04136	Transcription initiation factor TFIID subunit. (801 aa)
	prk-3	Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (407 aa)
	NCU03047	Uncharacterized protein. (345 aa)
	NCU02103	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1761 aa)
	NCU03138	Transcription initiation factor TFIID. (320 aa)
	NCU09748	Transcription initiation factor IIA subunit 2; TFIIA is a component of the transcription machinery of RNA polymerase II and plays an important role in transcriptional activation; Belongs to the TFIIA subunit 2 family. (115 aa)
	NCU09259	Uncharacterized protein. (625 aa)
	NCU02615	Uncharacterized protein. (421 aa)
	NCU02605	DNA-directed RNA polymerase I/II/III subunit 10. (84 aa)
	NCU02661	DNA-directed RNA polymerase II polypeptide. (171 aa)
	NCU02587	RNA polymerase II transcription factor B subunit 3. (362 aa)
	hat-2-2	Histone acetyl transferase-2. (1116 aa)
	rtf-1	General transcription and DNA repair factor IIH subunit rtf-1; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has b [...] (72 aa)
	NCU02052	Transcription initiation factor TFIId 127kD subunit, variant. (1870 aa)
	tcf-29	General transcription and DNA repair factor IIH subunit tcf-29; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has [...] (663 aa)
	NCU03782	DNA-directed RNA polymerase II subunit RPB11. (133 aa)
	NCU07289	Transcription initiation factor IIB, variant. (348 aa)
	NCU08729	Transcription initiation factor TFIID subunit 10; Functions as a component of the DNA-binding general transcription factor complex TFIID and the transcription regulatory histone acetylation (HAT) complexes SAGA and SLIK. Binding of TFIID to a promoter (with or without TATA element) is the initial step in preinitiation complex (PIC) formation. TFIID plays a key role in the regulation of gene expression by RNA polymerase II through different activities such as transcription activator interaction, core promoter recognition and selectivity, TFIIA and TFIIB interaction, chromatin modificati [...] (245 aa)
	NCU09378	DNA-directed RNA polymerase II polypeptide. (146 aa)
	NCU11012	DNA-directed RNA polymerase I. (160 aa)
	NCU03909	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase. (302 aa)
	NCU03464	Transcription factor TFIID complex subunit Taf13. (215 aa)
	NCU01580	Transcription factor TFIIH subunit Tfb4. (439 aa)
	NCU01551	Uncharacterized protein. (312 aa)
	NCU01831	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (469 aa)
	NCU01515	DNA-directed RNA polymerase II polypeptide. (337 aa)
	NCU07775	TAFII28 domain-containing protein. (410 aa)
	NCU03095	Transcription initiation factor TFIID subunit 7. (563 aa)

Your Current Organism:

Neurospora crassa

NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NCU00448	NCU01067	Q7RXZ6	Q1K8A2	DUF4211 domain-containing protein.	CYCLIN domain-containing protein.	0.718
NCU00448	NCU01322	Q7RXZ6	Q1K7U9	DUF4211 domain-containing protein.	Transcription factor TFIIE complex alpha subunit.	0.713
NCU00448	NCU01515	Q7RXZ6	Q1K5K1	DUF4211 domain-containing protein.	DNA-directed RNA polymerase II polypeptide.	0.741
NCU00448	NCU01580	Q7RXZ6	Q1K4W6	DUF4211 domain-containing protein.	Transcription factor TFIIH subunit Tfb4.	0.707
NCU00448	NCU01625	Q7RXZ6	Q7RXF5	DUF4211 domain-containing protein.	DNA repair helicase RAD3.	0.705
NCU00448	NCU01831	Q7RXZ6	Q1K578	DUF4211 domain-containing protein.	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	0.724
NCU00448	NCU02052	Q7RXZ6	V5IP24	DUF4211 domain-containing protein.	Transcription initiation factor TFIId 127kD subunit, variant.	0.893
NCU00448	NCU02223	Q7RXZ6	Q7S4H0	DUF4211 domain-containing protein.	TFIID_20kDa domain-containing protein.	0.896
NCU00448	NCU02587	Q7RXZ6	Q7SHN1	DUF4211 domain-containing protein.	RNA polymerase II transcription factor B subunit 3.	0.769
NCU00448	NCU02605	Q7RXZ6	Q7SG15	DUF4211 domain-containing protein.	DNA-directed RNA polymerase I/II/III subunit 10.	0.715
NCU00448	NCU02615	Q7RXZ6	Q7SG05	DUF4211 domain-containing protein.	Uncharacterized protein.	0.687
NCU00448	NCU02661	Q7RXZ6	Q7SH68	DUF4211 domain-containing protein.	DNA-directed RNA polymerase II polypeptide.	0.536
NCU00448	NCU03047	Q7RXZ6	Q7SD24	DUF4211 domain-containing protein.	Uncharacterized protein.	0.711
NCU00448	NCU03095	Q7RXZ6	Q7SCZ2	DUF4211 domain-containing protein.	Transcription initiation factor TFIID subunit 7.	0.893
NCU00448	NCU03138	Q7RXZ6	Q7SDV2	DUF4211 domain-containing protein.	Transcription initiation factor TFIID.	0.894
NCU00448	NCU03782	Q7RXZ6	V5IL63	DUF4211 domain-containing protein.	DNA-directed RNA polymerase II subunit RPB11.	0.672
NCU00448	NCU03909	Q7RXZ6	F5HDH6	DUF4211 domain-containing protein.	Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.	0.775
NCU00448	NCU04136	Q7RXZ6	Q1K7L8	DUF4211 domain-containing protein.	Transcription initiation factor TFIID subunit.	0.893
NCU00448	NCU04363	Q7RXZ6	Q7RWR7	DUF4211 domain-containing protein.	Uncharacterized protein.	0.713
NCU00448	NCU04508	Q7RXZ6	Q7RY55	DUF4211 domain-containing protein.	Uncharacterized protein.	0.785

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