30 items (Neurospora crassa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	NCU04363	Uncharacterized protein. (690 aa)
	NCU03782	DNA-directed RNA polymerase II subunit RPB11. (133 aa)
	NCU08995	Dual specificity phosphatase, variant. (621 aa)
	tcf-29	General transcription and DNA repair factor IIH subunit tcf-29; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has [...] (663 aa)
	rtf-1	General transcription and DNA repair factor IIH subunit rtf-1; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has b [...] (72 aa)
	NCU02587	RNA polymerase II transcription factor B subunit 3. (362 aa)
	NCU11012	DNA-directed RNA polymerase I. (160 aa)
	NCU01580	Transcription factor TFIIH subunit Tfb4. (439 aa)
	NCU01831	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family. (469 aa)
	NCU01515	DNA-directed RNA polymerase II polypeptide. (337 aa)
	prk-3	Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. (407 aa)
	NCU02661	DNA-directed RNA polymerase II polypeptide. (171 aa)
	NCU02605	DNA-directed RNA polymerase I/II/III subunit 10. (84 aa)
	NCU09259	Uncharacterized protein. (625 aa)
	NCU02103	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1761 aa)
	NCU03047	Uncharacterized protein. (345 aa)
	NCU09378	DNA-directed RNA polymerase II polypeptide. (146 aa)
	NCU08553	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (130 aa)
	rnp-2	mRNA-capping enzyme subunit alpha; Second step of mRNA capping. Transfer of the GMP moiety of GTP to the 5'-end of RNA via an enzyme-GMP covalent reaction intermediate (By similarity); Belongs to the eukaryotic GTase family. (402 aa)
	NCU08030	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively. (152 aa)
	NCU05305	DNA-directed RNA polymerase II polypeptide. (234 aa)
	NCU05523	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family. (501 aa)
	NCU06889	Uncharacterized protein. (532 aa)
	trf-3	Transcription elongation factor spt5; The spt4-spt5 complex mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing. This complex seems to be important for the stability of the RNA polymerase II elongation machinery on the chromatin template but not for the inherent ability of this machinery to translocate down the gene (By similarity). (1054 aa)
	NCU03971	mRNA cap guanine-N7 methyltransferase. (553 aa)
	NCU06438	DNA repair helicase RAD25. (862 aa)
	NCU05120	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1287 aa)
	NCU04508	Uncharacterized protein. (75 aa)
	NCU01625	DNA repair helicase RAD3. (806 aa)
	NCU01067	CYCLIN domain-containing protein. (427 aa)

Your Current Organism:

Neurospora crassa

NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NCU01067	NCU01515	Q1K8A2	Q1K5K1	CYCLIN domain-containing protein.	DNA-directed RNA polymerase II polypeptide.	0.937
NCU01067	NCU01580	Q1K8A2	Q1K4W6	CYCLIN domain-containing protein.	Transcription factor TFIIH subunit Tfb4.	0.999
NCU01067	NCU01625	Q1K8A2	Q7RXF5	CYCLIN domain-containing protein.	DNA repair helicase RAD3.	0.998
NCU01067	NCU01831	Q1K8A2	Q1K578	CYCLIN domain-containing protein.	General transcription and DNA repair factor IIH; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to TFIIK, in RNA transcription by RNA polymerase II; Belongs to the GTF2H2 family.	0.995
NCU01067	NCU02103	Q1K8A2	Q7SDN0	CYCLIN domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.904
NCU01067	NCU02587	Q1K8A2	Q7SHN1	CYCLIN domain-containing protein.	RNA polymerase II transcription factor B subunit 3.	0.999
NCU01067	NCU02605	Q1K8A2	Q7SG15	CYCLIN domain-containing protein.	DNA-directed RNA polymerase I/II/III subunit 10.	0.923
NCU01067	NCU02661	Q1K8A2	Q7SH68	CYCLIN domain-containing protein.	DNA-directed RNA polymerase II polypeptide.	0.896
NCU01067	NCU03047	Q1K8A2	Q7SD24	CYCLIN domain-containing protein.	Uncharacterized protein.	0.923
NCU01067	NCU03782	Q1K8A2	V5IL63	CYCLIN domain-containing protein.	DNA-directed RNA polymerase II subunit RPB11.	0.918
NCU01067	NCU03971	Q1K8A2	Q7RZ98	CYCLIN domain-containing protein.	mRNA cap guanine-N7 methyltransferase.	0.808
NCU01067	NCU04363	Q1K8A2	Q7RWR7	CYCLIN domain-containing protein.	Uncharacterized protein.	0.911
NCU01067	NCU04508	Q1K8A2	Q7RY55	CYCLIN domain-containing protein.	Uncharacterized protein.	0.929
NCU01067	NCU05120	Q1K8A2	Q7RYF4	CYCLIN domain-containing protein.	DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.	0.947
NCU01067	NCU05305	Q1K8A2	Q7S8Z5	CYCLIN domain-containing protein.	DNA-directed RNA polymerase II polypeptide.	0.936
NCU01067	NCU05523	Q1K8A2	Q7S6R6	CYCLIN domain-containing protein.	RNA polymerase II transcription factor B subunit 2; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.	0.995
NCU01067	NCU06438	Q1K8A2	Q7RYX9	CYCLIN domain-containing protein.	DNA repair helicase RAD25.	0.998
NCU01067	NCU06889	Q1K8A2	Q7S3G4	CYCLIN domain-containing protein.	Uncharacterized protein.	0.904
NCU01067	NCU08030	Q1K8A2	Q7SAL1	CYCLIN domain-containing protein.	DNA-directed RNA polymerases I, II, and III subunit RPABC3; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Common component of RNA polymerases I, II and III which synthesize ribosomal RNA precursors, mRNA precursors and many functional non- coding RNAs, and small RNAs, such as 5S rRNA and tRNAs, respectively.	0.929
NCU01067	NCU08553	Q1K8A2	Q7SBJ7	CYCLIN domain-containing protein.	DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.	0.935

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