38 items (Neurospora crassa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NCU11174	MIP-2A. (210 aa)
	NCU11228	DUF1339 domain-containing protein. (1112 aa)
	NCU11085	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (161 aa)
	NCU01664	DUF974 domain-containing protein. (447 aa)
	ypt-1	GTP-binding protein ypt1; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Ypt-1 regulates the trafficking of secretory vesicles from the endoplasmic reticulum (ER) to the Golgi. Plays a role in the initial events of the autophagic vacuole development which take [...] (203 aa)
	NCU04598	Uncharacterized protein. (1136 aa)
	NCU06715	Uncharacterized protein. (1454 aa)
	NCU06774	Intracellular protein transporter. (1089 aa)
	NCU06404	GTP-binding protein. (205 aa)
	NCU03888	DUF500 and SH3 domain-containing protein. (413 aa)
	NCU02225	Uncharacterized protein. (1631 aa)
	NCU05881	DUF500 and UBA/TS-N domain-containing protein. (701 aa)
	NCU04750	Uncharacterized protein. (1332 aa)
	NCU08874	Trafficking protein particle complex subunit; Plays a key role in the late stages of endoplasmic reticulum to Golgi traffic. (244 aa)
	NCU05234	GTP-binding protein ryh1. (213 aa)
	dcl-1	ATP-dependent helicase dcl-1; Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS). Part of a broad host defense response against viral infection and transposons. Controls the expression of the non-LTR retrotransposon Tad in the African strain, Adiomopoume. (1584 aa)
	NCU08844	Ysc84 domain-containing protein. (739 aa)
	NCU05288	Rab GDP dissociation inhibitor; Belongs to the Rab GDI family. (465 aa)
	NCU05213	Uncharacterized protein. (910 aa)
	NCU06403	Uncharacterized protein. (672 aa)
	NCU06212	Trafficking protein particle complex subunit 6B. (262 aa)
	dcl-2	ATP-dependent helicase dcl-2; Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS). Part of a broad host defense response against viral infection and transposons. Controls the expression of the non-LTR retrotransposon Tad in the African strain, Adiomopoume. (1534 aa)
	NCU03106	Uncharacterized protein. (336 aa)
	NCU03111	Uncharacterized protein. (235 aa)
	NCU00889	RAB family GTPase. (364 aa)
	NCU01860	Uncharacterized protein. (543 aa)
	NCU01908	Uncharacterized protein. (1069 aa)
	NCU01911	GDP/GTP exchange factor Sec2p. (688 aa)
	NCU03191	Rab proteins geranylgeranyltransferase; Belongs to the Rab GDI family. (490 aa)
	apg-13	Vacuolar fusion protein mon1; Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis; Belongs to the MON1/SAND family. (678 aa)
	NCU06435	VPS9 domain-containing protein, variant. (778 aa)
	NCU06176	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (187 aa)
	NCU12111	Uncharacterized protein. (207 aa)
	NCU05796	Trafficking protein particle complex subunit BET3. (193 aa)
	NCU01453	Rab18/RabC-family small GTPase. (235 aa)
	NCU07301	Uncharacterized protein. (752 aa)
	NCU04498	Uncharacterized protein. (498 aa)
	NCU01659	DDENN domain-containing protein. (1226 aa)

Your Current Organism:

Neurospora crassa

NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NCU00889	NCU05234	Q7SFE2	Q7S8H4	RAB family GTPase.	GTP-binding protein ryh1.	0.595
NCU00889	NCU05288	Q7SFE2	Q7S909	RAB family GTPase.	Rab GDP dissociation inhibitor; Belongs to the Rab GDI family.	0.432
NCU00889	NCU06403	Q7SFE2	Q7S9E4	RAB family GTPase.	Uncharacterized protein.	0.712
NCU00889	NCU06404	Q7SFE2	Q7RVG3	RAB family GTPase.	GTP-binding protein.	0.723
NCU01453	NCU03191	V5ILV9	Q7SGX8	Rab18/RabC-family small GTPase.	Rab proteins geranylgeranyltransferase; Belongs to the Rab GDI family.	0.682
NCU01453	NCU05234	V5ILV9	Q7S8H4	Rab18/RabC-family small GTPase.	GTP-binding protein ryh1.	0.702
NCU01453	NCU05288	V5ILV9	Q7S909	Rab18/RabC-family small GTPase.	Rab GDP dissociation inhibitor; Belongs to the Rab GDI family.	0.840
NCU01453	NCU06403	V5ILV9	Q7S9E4	Rab18/RabC-family small GTPase.	Uncharacterized protein.	0.436
NCU01453	NCU06404	V5ILV9	Q7RVG3	Rab18/RabC-family small GTPase.	GTP-binding protein.	0.403
NCU01453	ypt-1	V5ILV9	P33723	Rab18/RabC-family small GTPase.	GTP-binding protein ypt1; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Ypt-1 regulates the trafficking of secretory vesicles from the endoplasmic reticulum (ER) to the Golgi. Plays a role in the initial events of the autophagic vacuole development which take [...]	0.450
NCU01664	NCU01860	F5HCS7	Q7SHE6	DUF974 domain-containing protein.	Uncharacterized protein.	0.861
NCU01664	NCU02225	F5HCS7	Q7S4G8	DUF974 domain-containing protein.	Uncharacterized protein.	0.988
NCU01664	NCU03106	F5HCS7	Q7SFY8	DUF974 domain-containing protein.	Uncharacterized protein.	0.756
NCU01664	NCU03111	F5HCS7	Q7SFY3	DUF974 domain-containing protein.	Uncharacterized protein.	0.725
NCU01664	NCU04498	F5HCS7	V5IP18	DUF974 domain-containing protein.	Uncharacterized protein.	0.932
NCU01664	NCU04750	F5HCS7	Q7S6A3	DUF974 domain-containing protein.	Uncharacterized protein.	0.980
NCU01664	NCU05213	F5HCS7	Q7S9C1	DUF974 domain-containing protein.	Uncharacterized protein.	0.990
NCU01664	NCU05288	F5HCS7	Q7S909	DUF974 domain-containing protein.	Rab GDP dissociation inhibitor; Belongs to the Rab GDI family.	0.587
NCU01664	NCU05796	F5HCS7	V5ILR3	DUF974 domain-containing protein.	Trafficking protein particle complex subunit BET3.	0.987
NCU01664	NCU06176	F5HCS7	U9W838	DUF974 domain-containing protein.	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family.	0.993

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