48 items (Neurospora crassa) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NCU04498	Uncharacterized protein. (498 aa)
	NCU01659	DDENN domain-containing protein. (1226 aa)
	NCU08844	Ysc84 domain-containing protein. (739 aa)
	NCU05288	Rab GDP dissociation inhibitor; Belongs to the Rab GDI family. (465 aa)
	NCU05213	Uncharacterized protein. (910 aa)
	NCU06403	Uncharacterized protein. (672 aa)
	NCU06212	Trafficking protein particle complex subunit 6B. (262 aa)
	dcl-2	ATP-dependent helicase dcl-2; Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS). Part of a broad host defense response against viral infection and transposons. Controls the expression of the non-LTR retrotransposon Tad in the African strain, Adiomopoume. (1534 aa)
	NCU00889	RAB family GTPase. (364 aa)
	NCU03111	Uncharacterized protein. (235 aa)
	NCU03106	Uncharacterized protein. (336 aa)
	NCU01911	GDP/GTP exchange factor Sec2p. (688 aa)
	NCU03191	Rab proteins geranylgeranyltransferase; Belongs to the Rab GDI family. (490 aa)
	NCU11174	MIP-2A. (210 aa)
	NCU11228	DUF1339 domain-containing protein. (1112 aa)
	NCU11085	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (161 aa)
	NCU01664	DUF974 domain-containing protein. (447 aa)
	ypt-1	GTP-binding protein ypt1; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Ypt-1 regulates the trafficking of secretory vesicles from the endoplasmic reticulum (ER) to the Golgi. Plays a role in the initial events of the autophagic vacuole development which take [...] (203 aa)
	NCU03330	TBC domain-containing protein. (1137 aa)
	NCU07173	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (184 aa)
	NCU04598	Uncharacterized protein. (1136 aa)
	NCU06715	Uncharacterized protein. (1454 aa)
	NCU06774	Intracellular protein transporter. (1089 aa)
	NCU08499	GTPase-activating protein GYP5. (926 aa)
	NCU03237	Mitotic check point protein. (536 aa)
	NCU06404	GTP-binding protein. (205 aa)
	NCU04514	GTPase-activating protein gyp3. (1216 aa)
	NCU03888	DUF500 and SH3 domain-containing protein. (413 aa)
	NCU02211	Rab-GAP TBC domain-containing protein. (725 aa)
	NCU02225	Uncharacterized protein. (1631 aa)
	NCU05881	DUF500 and UBA/TS-N domain-containing protein. (701 aa)
	NCU04750	Uncharacterized protein. (1332 aa)
	NCU08874	Trafficking protein particle complex subunit; Plays a key role in the late stages of endoplasmic reticulum to Golgi traffic. (244 aa)
	NCU03661	GTPase-activating protein GYP7. (870 aa)
	NCU05234	GTP-binding protein ryh1. (213 aa)
	NCU08271	GTP-binding protein yptV5. (478 aa)
	dcl-1	ATP-dependent helicase dcl-1; Dicer-like endonuclease involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. Produces 21 to 25 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs leading to sequence-specific suppression of gene expression, called post-transcriptional gene silencing (PTGS). Part of a broad host defense response against viral infection and transposons. Controls the expression of the non-LTR retrotransposon Tad in the African strain, Adiomopoume. (1584 aa)
	NCU01908	Uncharacterized protein. (1069 aa)
	NCU01860	Uncharacterized protein. (543 aa)
	apg-13	Vacuolar fusion protein mon1; Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis; Belongs to the MON1/SAND family. (678 aa)
	apg-6	Autophagy-related protein 8; Ubiquitin-like modifier involved in autophagosomes formation. With cpr-1/atg4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also in [...] (121 aa)
	17E5.300	Probable Ras-related protein Rab7; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family. (205 aa)
	NCU06435	VPS9 domain-containing protein, variant. (778 aa)
	NCU06176	Trafficking protein particle complex subunit; Belongs to the TRAPP small subunits family. (187 aa)
	NCU12111	Uncharacterized protein. (207 aa)
	NCU05796	Trafficking protein particle complex subunit BET3. (193 aa)
	NCU01453	Rab18/RabC-family small GTPase. (235 aa)
	NCU07301	Uncharacterized protein. (752 aa)

Your Current Organism:

Neurospora crassa

NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
17E5.300	NCU00889	Q9C2L8	Q7SFE2	Probable Ras-related protein Rab7; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.	RAB family GTPase.	0.492
17E5.300	NCU01453	Q9C2L8	V5ILV9	Probable Ras-related protein Rab7; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.	Rab18/RabC-family small GTPase.	0.627
17E5.300	NCU03191	Q9C2L8	Q7SGX8	Probable Ras-related protein Rab7; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.	Rab proteins geranylgeranyltransferase; Belongs to the Rab GDI family.	0.904
17E5.300	NCU03237	Q9C2L8	Q7SGT3	Probable Ras-related protein Rab7; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.	Mitotic check point protein.	0.674
17E5.300	NCU03330	Q9C2L8	Q1K4P9	Probable Ras-related protein Rab7; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.	TBC domain-containing protein.	0.709
17E5.300	NCU03661	Q9C2L8	Q7S7B2	Probable Ras-related protein Rab7; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.	GTPase-activating protein GYP7.	0.972
17E5.300	NCU04514	Q9C2L8	Q7RY49	Probable Ras-related protein Rab7; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.	GTPase-activating protein gyp3.	0.676
17E5.300	NCU04598	Q9C2L8	Q1K6C1	Probable Ras-related protein Rab7; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.	Uncharacterized protein.	0.937
17E5.300	NCU05234	Q9C2L8	Q7S8H4	Probable Ras-related protein Rab7; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.	GTP-binding protein ryh1.	0.722
17E5.300	NCU05288	Q9C2L8	Q7S909	Probable Ras-related protein Rab7; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.	Rab GDP dissociation inhibitor; Belongs to the Rab GDI family.	0.943
17E5.300	NCU06403	Q9C2L8	Q7S9E4	Probable Ras-related protein Rab7; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.	Uncharacterized protein.	0.691
17E5.300	NCU06404	Q9C2L8	Q7RVG3	Probable Ras-related protein Rab7; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.	GTP-binding protein.	0.701
17E5.300	NCU06435	Q9C2L8	U9W2R8	Probable Ras-related protein Rab7; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.	VPS9 domain-containing protein, variant.	0.401
17E5.300	NCU07173	Q9C2L8	Q1K5W4	Probable Ras-related protein Rab7; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.	ADP-ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family.	0.527
17E5.300	NCU07301	Q9C2L8	V5IMU4	Probable Ras-related protein Rab7; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.	Uncharacterized protein.	0.410
17E5.300	NCU08271	Q9C2L8	Q7S8J6	Probable Ras-related protein Rab7; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.	GTP-binding protein yptV5.	0.584
17E5.300	NCU11174	Q9C2L8	A7UVT6	Probable Ras-related protein Rab7; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.	MIP-2A.	0.421
17E5.300	apg-13	Q9C2L8	Q870Q4	Probable Ras-related protein Rab7; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.	Vacuolar fusion protein mon1; Required for multiple vacuole delivery pathways including the cytoplasm to vacuole transport (Cvt), autophagy, pexophagy and endocytosis; Belongs to the MON1/SAND family.	0.946
17E5.300	apg-6	Q9C2L8	Q8WZY7	Probable Ras-related protein Rab7; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.	Autophagy-related protein 8; Ubiquitin-like modifier involved in autophagosomes formation. With cpr-1/atg4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also in [...]	0.715
17E5.300	ypt-1	Q9C2L8	P33723	Probable Ras-related protein Rab7; Protein transport. Probably involved in vesicular traffic (By similarity); Belongs to the small GTPase superfamily. Rab family.	GTP-binding protein ypt1; The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Ypt-1 regulates the trafficking of secretory vesicles from the endoplasmic reticulum (ER) to the Golgi. Plays a role in the initial events of the autophagic vacuole development which take [...]	0.643

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