STRINGSTRING
hog-1 hog-1 sho1 sho1 gh3-6 gh3-6 gh5-1 gh5-1 xr xr MCM7 MCM7 gh3-5 gh3-5 nrc-1 nrc-1 spo11 spo11 gh6-2 gh6-2 gh7-4 gh7-4 ena-1 ena-1 act act tub-2 tub-2 msh4 msh4 gh1-1 gh1-1 NCU03190 NCU03190
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hog-1Mitogen-activated protein kinase hog-1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes. Involved in ion flux-mediated turgor regulation; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily. (358 aa)
sho1High osmolarity signaling protein sho1; Plasma membrane osmosensor that activates the high osmolarity glycerol (HOG) MAPK signaling pathway in response to high osmolarity. (322 aa)
gh3-6Periplasmic beta-glucosidase. (870 aa)
gh5-1Endoglucanase gh5-1; Endoglucanase that plays an important role in biomass degradation. Binds onto plant cell walls to participate in the hydrolysis of cellulose. (390 aa)
xrXylose reductase. (322 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (824 aa)
gh3-5Beta-glucosidase; Belongs to the glycosyl hydrolase 3 family. (873 aa)
nrc-1MAPKK kinase. (914 aa)
spo11Meiosis-specific topoisomerase Spo11. (466 aa)
gh6-2Glucanase; Belongs to the glycosyl hydrolase family 6. (484 aa)
gh7-4Glucanase; Belongs to the glycosyl hydrolase 7 (cellulase C) family. (450 aa)
ena-1Calcium-transporting ATPase 3; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (1121 aa)
actActin; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells; Belongs to the actin family. (375 aa)
tub-2Tubulin beta chain; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. (447 aa)
msh4MutS ortholog 4 protein. (1318 aa)
gh1-1Beta-glucosidase, variant; Belongs to the glycosyl hydrolase 1 family. (476 aa)
NCU03190Rec8. (763 aa)
Your Current Organism:
Neurospora crassa
NCBI taxonomy Id: 367110
Other names: N. crassa OR74A, Neurospora crassa 74-OR23-1V A, Neurospora crassa 74-OR23-1VA, Neurospora crassa FGSC 2489, Neurospora crassa FGSC 9013, Neurospora crassa N150, Neurospora crassa OR74A
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