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| | Arg-4 | Arginine biosynthesis bifunctional protein ArgJ, mitochondrial; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate. (469 aa) |
| | NCU10107 | Ribose 5-phosphate isomerase. (173 aa) |
| | NCU10106 | Triosephosphate isomerase. (300 aa) |
| | trp-2 | Anthranilate synthase component I. (582 aa) |
| | NCU01328 | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (686 aa) |
| | NCU03748 | Saccharopine dehydrogenase. (448 aa) |
| | trp-1 | Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities. (762 aa) |
| | qa-2 | Catabolic 3-dehydroquinase; Is involved in the catabolism of quinate. Allows the utilization of quinate as carbon source via the beta-ketoadipate pathway; Belongs to the type-II 3-dehydroquinase family. (173 aa) |
| | his-3 | Histidine biosynthesis trifunctional protein. (870 aa) |
| | trp-3 | Tryptophan synthase; In the C-terminal section; belongs to the TrpB family. (708 aa) |
| | aga-1 | Arginase; Belongs to the arginase family. (358 aa) |
| | cit-1 | Citrate synthase, mitochondrial. (469 aa) |
| | leu-1 | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (368 aa) |
| | for | Serine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine. (480 aa) |
| | pgk-1 | Phosphoglycerate kinase. (418 aa) |
| | ilv-2 | Ketol-acid reductoisomerase, mitochondrial; Belongs to the ketol-acid reductoisomerase family. (402 aa) |
| | met-7 | Cystathionine gamma-synthase; Catalyzes the formation of L-cystathionine from O-succinyl-L- homoserine (OSHS) and L-cysteine, via a gamma-replacement reaction. In the absence of thiol, catalyzes gamma-elimination to form 2- oxobutanoate, succinate and ammonia (By similarity). (621 aa) |
| | eth-1 | S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate. (395 aa) |
| | fba | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (362 aa) |
| | gpd-1 | Glyceraldehyde-3-phosphate dehydrogenase. (338 aa) |
| | arg-6 | N-acetyl-gamma-glutamyl-phosphate reductase; In the N-terminal section; belongs to the acetylglutamate kinase family. (871 aa) |
| | aro-8 | Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family. (481 aa) |
| | aro-2 | Chorismate synthase; Bifunctional enzyme that possesses chorismate synthase and intrinsic flavin reductase activity, it uses NADPH to reduce FMN. (432 aa) |
| | pro-1 | Pyrroline-5-carboxylate reductase. (332 aa) |
| | NCU01786 | Ribose-phosphate pyrophosphokinase II. (412 aa) |
| | NCU01652 | O-acetylhomoserine. (454 aa) |
| | NCU03425 | Threonine synthase. (553 aa) |
| | arg-12 | Ornithine carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (385 aa) |
| | ilv-4 | Acetolactate synthase small subunit. (330 aa) |
| | NCU05093 | Cystathionine gamma-synthase. (657 aa) |
| | met-8 | Methionine synthase. (769 aa) |
| | his-6 | Imidazole glycerol phosphate synthase hisHF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The glutaminase domain produces the ammonia necessary for the cyclase domain to produce IGP and AICAR from PRFAR. The ammonia is channeled to the active site of the cyclase domain. Belongs to the HisA/HisF family. (553 aa) |
| | NCU04579 | Dihydroxy-acid dehydratase. (596 aa) |
| | pro-3 | Gamma-glutamyl phosphate reductase. (445 aa) |
| | NCU04303 | Asparagine synthetase 2. (581 aa) |
| | NCU04298 | Pentafunctional AROM polypeptide. (760 aa) |
| | NCU04292 | Branched-chain-amino-acid aminotransferase. (414 aa) |
| | NCU04280 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (809 aa) |
| | thr-4 | Homoserine kinase. (358 aa) |
| | NCU03761 | PALP domain-containing protein. (404 aa) |
| | NCU04118 | Aspartokinase. (522 aa) |
| | NCU03607 | Threonine dehydratase catabolic. (388 aa) |
| | arg-14 | Amino-acid acetyltransferase, mitochondrial; N-acetylglutamate synthase involved in arginine biosynthesis. (712 aa) |
| | met-5 | Homoserine O-acetyltransferase. (437 aa) |
| | met-2 | Cystathionine beta-lyase; Involved in de novo synthesis of methionine. Belongs to the trans-sulfuration enzymes family. (457 aa) |
| | cys-16 | Cystathionine gamma-lyase. (417 aa) |
| | lys-3 | L-aminoadipate-semialdehyde dehydrogenase large subunit. (1174 aa) |
| | emp-7 | Enolase. (438 aa) |
| | ace-8 | Pyruvate kinase. (527 aa) |
| | NCU01439 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (466 aa) |
| | ser-7 | Phosphoserine aminotransferase. (429 aa) |
| | his-7 | 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (257 aa) |
| | pro-4 | Glutamate 5-kinase. (468 aa) |
| | cys-17 | Cysteine synthase 1; Catalyzes the conversion of O-succinyl-L-serine into cysteine, the last step in the cysteine biosynthesis pathway. Can also use O-acetyl-L-serine; Belongs to the cysteine synthase/cystathionine beta- synthase family. (376 aa) |
| | trp-4 | Anthranilate phosphoribosyltransferase. (436 aa) |
| | NCU04401 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (288 aa) |
| | leu-2 | 3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (779 aa) |
| | ala | Alanine aminotransferase. (566 aa) |
| | NCU03935 | Homoserine dehydrogenase. (365 aa) |
| | NCU10020 | Methionine synthase. (385 aa) |
| | tpi-1 | Triosephosphate isomerase; Belongs to the triosephosphate isomerase family. (248 aa) |
| | NCU08216 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (528 aa) |
| | NCU02227 | Acetylornithine deacetylase. (452 aa) |
| | arg-10 | Argininosuccinate lyase. (466 aa) |
| | tca-3 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (784 aa) |
| | emp-6 | Phosphoglycerate mutase. (519 aa) |
| | cbs-2 | Putative serine hydroxymethyltransferase, mitochondrial; Interconversion of serine and glycine. (546 aa) |
| | ilv-6 | Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (405 aa) |
| | aro-6 | Phospho-2-dehydro-3-deoxyheptonate aldolase. (379 aa) |
| | NCU05254 | Ribose-phosphate pyrophosphokinase. (485 aa) |
| | NCU07725 | Chorismate mutase. (269 aa) |
| | tca-4 | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (379 aa) |
| | NCU06360 | Histidinol-phosphate aminotransferase. (401 aa) |
| | NCU07941 | Aspartate aminotransferase. (482 aa) |
| | NCU06974 | Histidinol-phosphatase; Belongs to the PHP hydrolase family. HisK subfamily. (316 aa) |
| | NCU05683 | Dihydroxy-acid dehydratase. (640 aa) |
| | NCU00519 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (251 aa) |
| | aro-7 | Phospho-2-dehydro-3-deoxyheptonate aldolase. (376 aa) |
| | NCU08117 | Uncharacterized protein. (675 aa) |
| | his-2 | ATP phosphoribosyltransferase. (337 aa) |
| | NCU02136 | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (324 aa) |
| | hom-1 | Aspartate-semialdehyde dehydrogenase. (362 aa) |
| | leu-4 | 2-isopropylmalate synthase. (625 aa) |
| | NCU02004 | Phosphoserine phosphatase. (496 aa) |
| | NCU00792 | Branched-chain-amino-acid aminotransferase. (413 aa) |
| | tca-6 | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (385 aa) |
| | lys-4 | Saccharopine dehydrogenase [NAD(+), L-lysine-forming]; Catalyzes the NAD(+)-dependent cleavage of saccharopine to L- lysine and 2-oxoglutarate, the final step in the alpha-aminoadipate (AAA) pathway for lysin biosynthesis; Belongs to the AlaDH/PNT family. (372 aa) |
| | NCU02479 | Glutamine synthetase; Belongs to the glutamine synthetase family. (484 aa) |
| | thr-5 | L-allo-threonine aldolase. (470 aa) |
| | lys-7 | Homoisocitrate dehydrogenase. (402 aa) |
| | NCU01870 | Eno3 protein. (441 aa) |
| | cys-12 | Cysteine synthase 2; Putative cysteine synthase that catalyzes the conversion of O-acetyl-L-serine (OAS) into cysteine, the last step in the cysteine biosynthesis pathway. However, in contrast to cysteine synthase cys-17, this CS-like protein may not function in cysteine biosynthesis. (456 aa) |
| | suc | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1192 aa) |
| | emp-3 | ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (845 aa) |
| | gln-1 | Glutamine synthetase. (362 aa) |
| | lys-4-2 | Homoaconitase, mitochondrial; Catalyzes the reversible hydration of cis-homoaconitate to (2R,3S)-homoisocitrate, a step in the alpha-aminoadipate pathway for lysine biosynthesis. (784 aa) |
| | aro-1 | 3-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family. (1563 aa) |
| | 65E11.030 | Imidazoleglycerol-phosphate dehydratase; Belongs to the imidazoleglycerol-phosphate dehydratase family. (229 aa) |
| | arg-8 | Acetylornithine aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (461 aa) |
| | NCU00468 | Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family. (445 aa) |
| | NCU00409 | Chorismate mutase/prephenate dehydratase, variant. (388 aa) |
| | NCU02450 | Threonine dehydratase. (584 aa) |
| | lys-5 | Homocitrate synthase, variant 1; Belongs to the alpha-IPM synthase/homocitrate synthase family. (425 aa) |
| | tca-5 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (462 aa) |
| | gln-2 | Glutamine synthetase. (394 aa) |
| | ppm-3 | Ribose 5-phosphate isomerase A. (366 aa) |
| | NCU06970 | Ribose-phosphate pyrophosphokinase II, variant. (323 aa) |
| | en(am)-2 | Glutamate synthase, variant. (2116 aa) |
| | NCU07982 | Acetolactate synthase. (689 aa) |
| | rpd | Ribose-phosphate pyrophosphokinase II. (501 aa) |
| | arg-1 | Argininosuccinate synthase. (417 aa) |
| | NCU08411 | Aspartate aminotransferase. (428 aa) |
| | tca-2 | Citrate synthase; Belongs to the citrate synthase family. (470 aa) |
| | NCU09116 | Aromatic aminotransferase Aro8, variant. (560 aa) |
