55 items (Arcobacter butzleri) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Abu_0585	Major facilitator superfamily transporter; Pfam match to PF07690 MFS_1, score 215.8, E-value 8.7E-062. (437 aa)
	Abu_0004	Probable thioredoxin reductase; Pfam matches to PF00070 Pyr_redox, score 52.8, E-value 5.8E-015, and to PF00890 FAD_binding_2, score 16.4, E-value 7.4E-005. (323 aa)
	Abu_0016	Conserved hypothetical protein, putative MFS permease; Pfam match to PF07690 MFS_1, score 99.6, E-value 1.1E-027. (392 aa)
	pstS	Phosphate ABC transporter, periplasmic phosphate-binding protein. (351 aa)
	appA	Oligopeptide ABC transporter, periplasmic substrate-binding protein; Pfam match to PF00496 SBP_bac_5, score 246.3, E-value 5.7E-071. (516 aa)
	Abu_0106	ABC transporter, periplasmic substrate-binding protein, putative; Pfam match to PF02470 MCE, score 70.7, E-value 4.3E-018. (302 aa)
	Abu_0216	Oligopeptide ABC transporter, permease protein; Pfam match to PF00528 BPD_transp_1, score 154.1, E-value 3.4E-043. (319 aa)
	Abu_0271	Conserved hypothetical protein. (399 aa)
	tsaA	Alkyl hydroperoxide reductase/ Thiol specific antioxidant; Pfam match to PF00578 AhpC-TSA, score 325.3, E-value 9.9E-095. (198 aa)
	ndk	Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (137 aa)
	Abu_0330	MFS family, AmpG related permease; Pfam match to PF07690 MFS_1, score 94.5, E-value 2.9E-026. (391 aa)
	Abu_0336	Major facilitator superfamily transporter; Pfam match to PF07690 MFS_1, score 159.7, E-value 7.1E-045. (391 aa)
	Abu_0337	Major facilitator superfamily transporter; Pfam match to PF07690 MFS_1, score 67.7, E-value 8.6E-019. (402 aa)
	Abu_0338	ABC transporter, ATP-binding/permease protein; Pfam matches to PF00005 ABC_tran, score 208, E-value 2E-059, and to PF00664 ABC_membrane, score 34, E-value 8.3E-009. (593 aa)
	Abu_0339	ABC transporter, ATP-binding/permease protein; Pfam matches to PF00005 ABC_tran, score 210.6, E-value 3.3E-060, and to PF00664 ABC_membrane, score 36.2, E-value 2.2E-009. (597 aa)
	secD	Protein-export membrane protein SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (521 aa)
	secF	Protein-export membrane protein SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. (322 aa)
	Abu_0457	Conserved hypothetical protein. (110 aa)
	tpx	Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (179 aa)
	Abu_0594	Protein tyrosine phosphatase; Pfam match to PF01451 LMWPc, score 128, E-value 2.4E-035; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (152 aa)
	rpoZ	DNA-directed RNA polymerase, omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (72 aa)
	Abu_0675	ABC transporter, ATP-binding/permease protein; Pfam matches to PF00005 ABC_tran, score 208.3, E-value 1.6E-059, and to PF00664 ABC_membrane, score 23.1, E-value 7E-006. (566 aa)
	secY	Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (420 aa)
	msbA	Multidrug resistance protein MsbA; Pfam matches to PF00005 ABC_tran, score 182.4, E-value 1E-051, and to PF00664 ABC_membrane, score 135.5, E-value 1.4E-037. (569 aa)
	Abu_0894	ABC transporter, permease protein; Pfam match to PF00528 BPD_transp_1, score 113.6, E-value 5.3E-031. (281 aa)
	Abu_0911	Conserved hypothetical protein; Pfam match to PF03486 HI0933_like, score 23.5, E-value 1.5E-006. (197 aa)
	Abu_0940	Adhesin/haemagglutinin, HecA family; Pfam match to PF05860 Haemagg_act, score 134.4, E-value 2.9E-037. (3033 aa)
	Abu_0943	Hypothetical protein. (792 aa)
	rpoA	DNA-directed RNA polymerase, alpha chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (332 aa)
	Abu_1106	ABC transporter, ATP-binding protein; Pfam match to PF00005 ABC_tran, score 166.4, E-value 6.6E-047. (589 aa)
	fsr	Fosmidomycin resistance protein; Pfam match to PF07690 MFS_1, score 159.2, E-value 9.5E-045. (384 aa)
	secA	Protein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (872 aa)
	Abu_1347	Hypothetical protein. (212 aa)
	Abu_1417	Conserved hypothetical protein. (100 aa)
	katG	Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (735 aa)
	Abu_1553	Protozoan/cyanobacterial globin-like protein; Pfam match to PF01152 Bac_globin, score 29.6, E-value 2.1E-007. (144 aa)
	sodB	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (191 aa)
	msrA	Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (164 aa)
	Abu_1710	Conserved hypothetical protein. (248 aa)
	bcp	Bacterioferritin comigratory protein, alkyl hydroperoxide reductase/thiol specific antioxidant; Pfam match to PF00578 AhpC-TSA, score 14.5, E-value 8.7E-013. (168 aa)
	ahpC	Alkyl hydroperoxide reductase/ Thiol specific antioxidant; Pfam match to PF00578 AhpC-TSA, score 325.3, E-value 9.9E-095. (198 aa)
	trx1	Thioredoxin; Pfam match to PF00085 Thioredoxin, score 139.3, E-value 9.7E-039; Belongs to the thioredoxin family. (105 aa)
	rpoC	DNA-directed RNA polymerase, beta' chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1511 aa)
	rpoB	DNA-directed RNA polymerase, beta chain; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1382 aa)
	secE	Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (60 aa)
	arsC	Arsenate reductase; Pfam match to PF01451 LMWPc, score 86.9, E-value 5.7E-023; Belongs to the low molecular weight phosphotyrosine protein phosphatase family. (132 aa)
	Abu_1937	Putative integral membrane protein; Pfam match to PF07690 MFS_1, score 91.6, E-value 1.8E-025. (394 aa)
	araJ	Putative transport protein AraJ; Pfam match to PF07690 MFS_1, score 161.4, E-value 2.2E-045. (381 aa)
	ribD	Bifunctional riboflavin biosynthesis protein RibD; Pfam match to PF00383 dCMP_cyt_deam_1, score 117.5, E-value 3.5E-032. (334 aa)
	trxB	Thioredoxin reductase; Pfam match to PF07992 Pyr_redox_2, score 142.8, E-value 8.4E-040. (309 aa)
	trx2	Thioredoxin; Pfam match to PF00085 Thioredoxin, score 138.1, E-value 2.1E-038; Belongs to the thioredoxin family. (105 aa)
	Abu_2094	Major facilitator superfamily transporter; Pfam match to PF07690 MFS_1, score 126.7, E-value 6.1E-035. (377 aa)
	Abu_2157	Major facilitator superfamily transporter; Pfam match to PF07690 MFS_1, score 132, E-value 9.7E-037. (363 aa)
	Abu_2226	Major facilitator superfamily transporter, Bcr/CflA subfamily; Pfam match to PF07690 MFS_1, score 156.6, E-value 5.9E-044. (396 aa)
	secG	Protein-export membrane protein SecG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (115 aa)

Your Current Organism:

Arcobacter butzleri

NCBI taxonomy Id: 367737
Other names: A. butzleri RM4018, Arcobacter butzleri RM4018, Arcobacter butzleri str. RM4018, Arcobacter butzleri strain RM4018

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Abu_0004	Abu_0457	Abu_0004	Abu_0457	Probable thioredoxin reductase; Pfam matches to PF00070 Pyr_redox, score 52.8, E-value 5.8E-015, and to PF00890 FAD_binding_2, score 16.4, E-value 7.4E-005.	Conserved hypothetical protein.	0.500
Abu_0004	ahpC	Abu_0004	Abu_1879	Probable thioredoxin reductase; Pfam matches to PF00070 Pyr_redox, score 52.8, E-value 5.8E-015, and to PF00890 FAD_binding_2, score 16.4, E-value 7.4E-005.	Alkyl hydroperoxide reductase/ Thiol specific antioxidant; Pfam match to PF00578 AhpC-TSA, score 325.3, E-value 9.9E-095.	0.541
Abu_0004	trx1	Abu_0004	Abu_1880	Probable thioredoxin reductase; Pfam matches to PF00070 Pyr_redox, score 52.8, E-value 5.8E-015, and to PF00890 FAD_binding_2, score 16.4, E-value 7.4E-005.	Thioredoxin; Pfam match to PF00085 Thioredoxin, score 139.3, E-value 9.7E-039; Belongs to the thioredoxin family.	0.500
Abu_0004	trx2	Abu_0004	Abu_2091	Probable thioredoxin reductase; Pfam matches to PF00070 Pyr_redox, score 52.8, E-value 5.8E-015, and to PF00890 FAD_binding_2, score 16.4, E-value 7.4E-005.	Thioredoxin; Pfam match to PF00085 Thioredoxin, score 138.1, E-value 2.1E-038; Belongs to the thioredoxin family.	0.500
Abu_0004	trxB	Abu_0004	Abu_2090	Probable thioredoxin reductase; Pfam matches to PF00070 Pyr_redox, score 52.8, E-value 5.8E-015, and to PF00890 FAD_binding_2, score 16.4, E-value 7.4E-005.	Thioredoxin reductase; Pfam match to PF07992 Pyr_redox_2, score 142.8, E-value 8.4E-040.	0.908
Abu_0004	tsaA	Abu_0004	Abu_0289	Probable thioredoxin reductase; Pfam matches to PF00070 Pyr_redox, score 52.8, E-value 5.8E-015, and to PF00890 FAD_binding_2, score 16.4, E-value 7.4E-005.	Alkyl hydroperoxide reductase/ Thiol specific antioxidant; Pfam match to PF00578 AhpC-TSA, score 325.3, E-value 9.9E-095.	0.541
Abu_0216	Abu_0894	Abu_0216	Abu_0894	Oligopeptide ABC transporter, permease protein; Pfam match to PF00528 BPD_transp_1, score 154.1, E-value 3.4E-043.	ABC transporter, permease protein; Pfam match to PF00528 BPD_transp_1, score 113.6, E-value 5.3E-031.	0.999
Abu_0216	appA	Abu_0216	Abu_0096	Oligopeptide ABC transporter, permease protein; Pfam match to PF00528 BPD_transp_1, score 154.1, E-value 3.4E-043.	Oligopeptide ABC transporter, periplasmic substrate-binding protein; Pfam match to PF00496 SBP_bac_5, score 246.3, E-value 5.7E-071.	0.994
Abu_0330	Abu_0337	Abu_0330	Abu_0337	MFS family, AmpG related permease; Pfam match to PF07690 MFS_1, score 94.5, E-value 2.9E-026.	Major facilitator superfamily transporter; Pfam match to PF07690 MFS_1, score 67.7, E-value 8.6E-019.	0.926
Abu_0336	Abu_0337	Abu_0336	Abu_0337	Major facilitator superfamily transporter; Pfam match to PF07690 MFS_1, score 159.7, E-value 7.1E-045.	Major facilitator superfamily transporter; Pfam match to PF07690 MFS_1, score 67.7, E-value 8.6E-019.	0.868
Abu_0336	Abu_0338	Abu_0336	Abu_0338	Major facilitator superfamily transporter; Pfam match to PF07690 MFS_1, score 159.7, E-value 7.1E-045.	ABC transporter, ATP-binding/permease protein; Pfam matches to PF00005 ABC_tran, score 208, E-value 2E-059, and to PF00664 ABC_membrane, score 34, E-value 8.3E-009.	0.854
Abu_0336	Abu_0339	Abu_0336	Abu_0339	Major facilitator superfamily transporter; Pfam match to PF07690 MFS_1, score 159.7, E-value 7.1E-045.	ABC transporter, ATP-binding/permease protein; Pfam matches to PF00005 ABC_tran, score 210.6, E-value 3.3E-060, and to PF00664 ABC_membrane, score 36.2, E-value 2.2E-009.	0.844
Abu_0337	Abu_0330	Abu_0337	Abu_0330	Major facilitator superfamily transporter; Pfam match to PF07690 MFS_1, score 67.7, E-value 8.6E-019.	MFS family, AmpG related permease; Pfam match to PF07690 MFS_1, score 94.5, E-value 2.9E-026.	0.926
Abu_0337	Abu_0336	Abu_0337	Abu_0336	Major facilitator superfamily transporter; Pfam match to PF07690 MFS_1, score 67.7, E-value 8.6E-019.	Major facilitator superfamily transporter; Pfam match to PF07690 MFS_1, score 159.7, E-value 7.1E-045.	0.868
Abu_0337	Abu_0338	Abu_0337	Abu_0338	Major facilitator superfamily transporter; Pfam match to PF07690 MFS_1, score 67.7, E-value 8.6E-019.	ABC transporter, ATP-binding/permease protein; Pfam matches to PF00005 ABC_tran, score 208, E-value 2E-059, and to PF00664 ABC_membrane, score 34, E-value 8.3E-009.	0.906
Abu_0337	Abu_0339	Abu_0337	Abu_0339	Major facilitator superfamily transporter; Pfam match to PF07690 MFS_1, score 67.7, E-value 8.6E-019.	ABC transporter, ATP-binding/permease protein; Pfam matches to PF00005 ABC_tran, score 210.6, E-value 3.3E-060, and to PF00664 ABC_membrane, score 36.2, E-value 2.2E-009.	0.898
Abu_0338	Abu_0336	Abu_0338	Abu_0336	ABC transporter, ATP-binding/permease protein; Pfam matches to PF00005 ABC_tran, score 208, E-value 2E-059, and to PF00664 ABC_membrane, score 34, E-value 8.3E-009.	Major facilitator superfamily transporter; Pfam match to PF07690 MFS_1, score 159.7, E-value 7.1E-045.	0.854
Abu_0338	Abu_0337	Abu_0338	Abu_0337	ABC transporter, ATP-binding/permease protein; Pfam matches to PF00005 ABC_tran, score 208, E-value 2E-059, and to PF00664 ABC_membrane, score 34, E-value 8.3E-009.	Major facilitator superfamily transporter; Pfam match to PF07690 MFS_1, score 67.7, E-value 8.6E-019.	0.906
Abu_0338	Abu_0339	Abu_0338	Abu_0339	ABC transporter, ATP-binding/permease protein; Pfam matches to PF00005 ABC_tran, score 208, E-value 2E-059, and to PF00664 ABC_membrane, score 34, E-value 8.3E-009.	ABC transporter, ATP-binding/permease protein; Pfam matches to PF00005 ABC_tran, score 210.6, E-value 3.3E-060, and to PF00664 ABC_membrane, score 36.2, E-value 2.2E-009.	0.818
Abu_0339	Abu_0336	Abu_0339	Abu_0336	ABC transporter, ATP-binding/permease protein; Pfam matches to PF00005 ABC_tran, score 210.6, E-value 3.3E-060, and to PF00664 ABC_membrane, score 36.2, E-value 2.2E-009.	Major facilitator superfamily transporter; Pfam match to PF07690 MFS_1, score 159.7, E-value 7.1E-045.	0.844