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silP silP BAD_0058 BAD_0058 dnaB dnaB ftsH ftsH BAD_0415 BAD_0415 arc arc BAD_0562 BAD_0562 clpC1 clpC1 clpX clpX ychF ychF uvrB uvrB uvrD1 uvrD1 BAD_0715 BAD_0715 ruvA ruvA ruvB ruvB uvrA uvrA mrp mrp ctpE ctpE BAD_1111 BAD_1111 BAD_1163 BAD_1163 BAD_1227 BAD_1227 BAD_1280 BAD_1280 actP actP BAD_1305 BAD_1305 moxR moxR BAD_1354 BAD_1354 clpB clpB BAD_1581 BAD_1581 parA parA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
silPCOG family: cation transport ATPases; Orthologue of BL0409; PFAM_ID: E1-E2_ATPase; PFAM_ID: Hydrolase. (311 aa)
BAD_0058Probable cation-transporting ATPase V; COG family: cation transport ATPases; Orthologue of BL0554; PFAM_ID: Hydrolase; PFAM_ID:E1-E2_ATPase. (769 aa)
dnaBReplicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (485 aa)
ftsHHypothetical protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (699 aa)
BAD_0415Orthologue of Rv2477c_BL1688; Probable ATPbinding protein ABC-transporter probably involved in macrolide transport. (551 aa)
arcProbable Aaa-family ATPase; COG family: ATPases of the Aaa+ class; Orthologue of BL1794; PFAM_ID:AAA. (515 aa)
BAD_0562Widely conserved MoxR-like protein in magnesium chelatase family; COG family: MoxR-like ATPases; Orthologue of BL1811; PFAM_ID: AAA; PFAM_ID: Mg_chelatase. (355 aa)
clpC1Orthologue of Rv3596c_BL0010; ProbableclpC1_ ATP-dependent protease ATP-binding subunit (EC3.4.-.-); Belongs to the ClpA/ClpB family. (864 aa)
clpXATP-dependent specificity component of the Clp protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (473 aa)
ychFWidely conserved hypothetical GTPase-like protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (366 aa)
uvrBUvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] (696 aa)
uvrD1ATP-dependent DNA helicase PcrA; Orthologue of Rv0949_BL0890; ProbableuvrD1_ ATP dependent DNA helicase II (EC 3.6.1.-). (879 aa)
BAD_0715Hypothetical protein; COG family: putative aromatic ring hydroxylatingenzyme; Orthologue of BL0867; PFAM_ID: DUF59. (195 aa)
ruvAHolliday junction ATP-dependent DNA helicase ruvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (205 aa)
ruvBHolliday junction ATP-dependent DNA helicase ruvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (362 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (995 aa)
mrpHypothetical protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (373 aa)
ctpEProbable cation-transporting ATPase; COG family: cation transport ATPases; Orthologue of BL1396; PFAM_ID: E1-E2_ATPase; PFAM_ID: Hydrolase. (824 aa)
BAD_1111Hypothetical protein; Orthologue of BL1314. (765 aa)
BAD_1163COG family: superfamily I DNA and RNAhelicases; Orthologue of BL0092; PFAM_ID: UvrD-helicase; UvrD. (499 aa)
BAD_1227Putative helicase IV; Orthologue of YPO1440. (690 aa)
BAD_1280Type II restriction-modification systemrestriction subunit; Orthologue of BC0939. (167 aa)
actPActP copper transport ATPase; Orthologue of SMa1013; Silver efflux P-type ATPase [Psychrobacter arcticus 273-4]; Start changed for RBS and homology with other ATPases. (1000 aa)
BAD_1305Widely conserved ATP-dependent DNA helicase; COG family: superfamily I DNA and RNA helicases; Orthologue of BL1196; PFAM_ID:UvrD-helicase; Belongs to the helicase family. UvrD subfamily. (1356 aa)
moxRMethanol dehydrogenase regulatory protein homolog; COG family: MoxR-like ATPases; Orthologue of BL1199a; PFAM_ID:Mg_chelatase. (449 aa)
BAD_1354Hypothetical protein; Orthologue of BL1511. (356 aa)
clpBChaperone clpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (905 aa)
BAD_1581Calcium-transporting ATPase; Orthologue of ABC2324. (1024 aa)
parACOG family: ATPases involved in chromosomepartitioning; Orthologue of BL0647; PFAM_ID: ParA; PFAM_ID: fer4_NifH. (314 aa)
Your Current Organism:
Bifidobacterium adolescentis
NCBI taxonomy Id: 367928
Other names: B. adolescentis ATCC 15703, Bifidobacterium adolescentis ATCC 15703, Bifidobacterium adolescentis str. ATCC 15703, Bifidobacterium adolescentis strain ATCC 15703
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