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| | BAD_1612 | Widely conserved protein with eukaryotic protein kinase domain; COG family: serine_threonine protein kinases; Orthologue of BL0660; PFAM_ID: pkinase. (718 aa) |
| | dnaA | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (499 aa) |
| | recF | Recombination protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (403 aa) |
| | gyrB | DNA gyrase (topoisomerase II) B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-depen [...] (712 aa) |
| | gyrA | DNA gyrase (topoisomerase II) A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-depen [...] (886 aa) |
| | trpS | COG family:tryptophanyl-tRNA synthetase; COG0180; Orthologue of BL0600; PFAM_ID: tRNA-synt_1b; Tryptophan-tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family. (366 aa) |
| | pknB | COG family: serine_threonine protein kinases; Orthologue of BL0589; PFAM_ID: pkinase. (686 aa) |
| | pknA | COG family: serine_threonine protein kinases; Orthologue of BL0588; PFAM_ID: pkinase. (314 aa) |
| | BAD_0058 | Probable cation-transporting ATPase V; COG family: cation transport ATPases; Orthologue of BL0554; PFAM_ID: Hydrolase; PFAM_ID:E1-E2_ATPase. (769 aa) |
| | purA | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (428 aa) |
| | BAD_0072 | Branched-chain amino acid transport system ATP-binding protein; Orthologue of Tfu_1184. (316 aa) |
| | LivF | ABC-type branched-chain amino acid transport systems ATPase component; Orthologue of Tfu_1185. (269 aa) |
| | BAD_0085 | COG family: ABC-type transport systems_ involved inlipoprotein release_ permease components; Orthologue of BL0155; PFAM_ID: DUF214. (1053 aa) |
| | BAD_0093 | COG family: ABC-type multidrug_protein_lipidtransport system_ ATPase component; Orthologue of BL0162; PFAM_ID: ABC_membrane; PFAM_ID: ABC_tran. (583 aa) |
| | BAD_0094 | Probable permease protein of ABC transporter system; Orthologue of str0434_BL0163. (613 aa) |
| | BAD_0102 | COG family: ABC-type transport systems_ involved inlipoprotein release_ ATPase components; Orthologue of BL0450; PFAM_ID: ABC_tran. (291 aa) |
| | ftsY | FtsY signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (420 aa) |
| | dnaB | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (485 aa) |
| | BAD_0117 | Hypothetical protein; COG family: UDP-N-acetylmuramyl tripeptidesynthase; Orthologue of BL0430; PFAM_ID: Mur_ligase. (527 aa) |
| | BAD_0120 | COG family: predicted unusual protein kinase; Orthologue of BL0427; PFAM_ID: ABC1. (501 aa) |
| | upp | Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (213 aa) |
| | ppk | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (744 aa) |
| | BAD_0128 | Hypothetical protein; COG family: septum formation inhibitor-activatingATPase; Orthologue of BL0509. (274 aa) |
| | BAD_0129 | Hypothetical protein; COG family: predicted ATPases involved in pili andflagella biosynthesis_ VirB11 family; Orthologue of BL0508; PFAM_ID: GSPII_E. (330 aa) |
| | dnaX | DNA polymerase III subunit gamma_tau; Orthologue of BL0500; Plays a role in assembling DnaB onto the primertemplate and interacts with the core polymerase. (814 aa) |
| | pknB-2 | COG family: serine_threonine protein kinases; Orthologue of HTA426; PFAM_ID: pkinase. (847 aa) |
| | BAD_0147 | Hypothetical protein; Orthologue of CE1245. (260 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (217 aa) |
| | fhs | Formate-tetrahydrofolate ligase; COG family: formyltetrahydrofolate synthetase; Orthologue of BL0478; PFAM_ID:FTHFS; formyltetrahydrofolate synthetase; Belongs to the formate--tetrahydrofolate ligase family. (527 aa) |
| | gltX | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (506 aa) |
| | ddlA | D-alanine-D-alanine ligase; Cell wall formation. (378 aa) |
| | msiK | Similar to ATP binding protein of ABC transporter; COG family: ABC-typesugar_spermidine_putrescine_iron_thiamine transportsystems_ ATPase component; Orthologue of BL0341; PFAM_ID: ABC_tran; Belongs to the ABC transporter superfamily. (395 aa) |
| | BAD_0199 | Putative gluconokinase; Orthologue of SCO1679. (178 aa) |
| | recG | ATP-dependent DNA helicase; COG family: RecG-like helicases; Orthologue of BL0329; PFAM_ID: helicase_C; PFAM_ID:DEAD. (893 aa) |
| | ffh | Signal recognition particle protein; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (549 aa) |
| | cysS | cysteinyl-tRNA synthetase; Catalyzes a two-step reaction_charges a cysteineby linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; Orthologue of BL0301; Belongs to the class-I aminoacyl-tRNA synthetase family. (543 aa) |
| | BAD_0214 | COG family: ATPase components of ABC transporterswith duplicated ATPase domains; Orthologue of BL0299; PFAM_ID: ABC_tran. (718 aa) |
| | BAD_0235 | COG family: ABC-type transport systems_ involved inlipoprotein release_ ATPase components; Orthologue of BL0932_BL1277; PFAM_ID: ABC_tran. (241 aa) |
| | obg | GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (563 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (377 aa) |
| | BAD_0254 | JadJ; COG family: biotin carboxylase; Orthologue of BL1535. (634 aa) |
| | pstB | Phosphate import ATP-binding protein pstB; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (259 aa) |
| | BAD_0289 | Hypothetical protein; COG family: 5-formyltetrahydrofolate cyclo-ligase; Orthologue of BL1555; PFAM_ID: 5-FTHF_cyc-lig; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (206 aa) |
| | groES | groES protein; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (97 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (186 aa) |
| | BAD_0350 | Hypothetical protein; COG family: uncharacterized Bcr; Orthologue of BL1609. (726 aa) |
| | infB | Translation initiation factor IF-2; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (931 aa) |
| | ribF | Riboflavin kinase; COGfamily: FAD synthase; Fad pyrophosphorylase; Fad synthetase; Orthologue of BL1619; PFAM_ID: FAD_Synth. (409 aa) |
| | radA | Alkylation damage repair protein; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (472 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (428 aa) |
| | lysS | lysyl-tRNA synthetase 1; Catalyzes a two-step reaction_ first charging alysine molecule by linking its carboxyl group to thealpha-phosphate of ATP_ followed by transfer of theaminoacyl-adenylate to its tRNA; Orthologue of BL1654; Belongs to the class-II aminoacyl-tRNA synthetase family. (587 aa) |
| | BAD_0386 | COG family: universal stress protein UspA andrelated nucleotide-binding proteins; Orthologue of BL1664; PFAM_ID: Usp. (351 aa) |
| | ftsH | Hypothetical protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (699 aa) |
| | folE | GTP cyclohydrolase I; Involved in the first step of tetrahydrofolatebiosynthesis; catalyzes the formation of formate and2-amino-4-hydroxy-6-(erythro-1_2_3- trihydroxypropyl)dihydropteridine triphosphate from GTPand water; forms a homopolymer; Orthologue of BL1683_Tfu_2895. (211 aa) |
| | sulD | Aldolase-pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (516 aa) |
| | BAD_0415 | Orthologue of Rv2477c_BL1688; Probable ATPbinding protein ABC-transporter probably involved in macrolide transport. (551 aa) |
| | xylB | Xylulose kinase; COG family: sugar (pentuloseand hexulose) kinases; Orthologue of BL1709; PFAM_ID: FGGY; Xylulokinase. (506 aa) |
| | BAD_0446 | COG family: ABC-type branched-chain amino acidtransport systems_ ATPase component; Orthologue of BL1717. (270 aa) |
| | BAD_0447 | COG family: ABC-type branched-chain amino acidtransport systems_ ATPase component; Orthologue of BL1718. (234 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves dea [...] (605 aa) |
| | ftsE | FtsE-like ATP binding protein in cell division; Part of the ABC transporter FtsEX involved in cellular division. (412 aa) |
| | ftsX | FtsX-like protein in cell division; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (308 aa) |
| | BAD_0472 | ATP binding protein of ABC transporter; COG family: ABC-type polar amino acid transportsystem_ ATPase component; Orthologue of BL1176. (269 aa) |
| | coaX | Hypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (256 aa) |
| | BAD_0481 | Probable ABC transporter permease protein for peptides; COG family: ABC-type dipeptide_oligopeptide_nickeltransport systems_ permease components; Orthologue of BL1159. (285 aa) |
| | oppD | Probable ATP-binding protein of ABC transporter system for peptides; COG family: ATPase components of variousABC-type transport systems_ contain duplicated ATPase; Orthologue of BL1158. (276 aa) |
| | oppF | Probable ATP binding protein of ABC transporter for peptides; COG family: ATPase components of variousABC-type transport systems_ contain duplicated ATPase; Orthologue of BL1157. (251 aa) |
| | BAD_0486 | ABC transporter; ATP-binding protein; Identified by sequence similarity; Orthologue of Lxx18820. (221 aa) |
| | BAD_0487 | Hypothetical protein; Orthologue of Lxx17710. (382 aa) |
| | BAD_0488 | ABC transporter; ATP-binding protein; Orthologue of lp_2743. (302 aa) |
| | recQ | COG family: superfamily II DNA helicase; Orthologue of BL1153; PFAM_ID: HRDC; PFAM_ID: helicase_C; PFAM_ID:DEAD. (674 aa) |
| | BAD_0501 | Translation elongation factors; GTPase; Orthologue of LBA0051. (662 aa) |
| | gltL | ATP binding protein of ABC transporter for glutamate_aspartate; COG family: ABC-type polar amino acidtransport system_ ATPase component; Orthologue of BL0076; PFAM_ID: ABC_tran. (292 aa) |
| | BAD_0510 | COG family: ABC-type transport systems_ involved inlipoprotein release_ ATPase components; Orthologue of BL1135; PFAM_ID: ABC_tran. (243 aa) |
| | BAD_0512 | Protein with weak similarity to components of ABC transporter; COG family: ABC-type transport systems_ involved inlipoprotein release_ permease components; Orthologue of BL1133; PFAM_ID: DUF214. (503 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (376 aa) |
| | purD | COG family:phosphoribosylamine-glycine ligase; GarS:glycinamide ribonucleotide synthetase;phosphoribosylglycinamide synthetase; Orthologue of BL1123; PFAM_ID: GARS; Belongs to the GARS family. (420 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; Catalyzes the formation of1-(5-phosphoribosyl)-5-aminoimidazole from2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP inpurine biosynthesis; Orthologue of BL1122. (344 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Catalyzes the formation of(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate andL-aspartate in purine biosynthesis; Orthologue of BL1107; Belongs to the SAICAR synthetase family. (250 aa) |
| | purT | Probable phosphoribosylglycinamide formyltransferase 2; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (417 aa) |
| | BAD_1213 | Possible glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. (432 aa) |
| | fusA1 | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (709 aa) |
| | tuf | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (399 aa) |
| | carA | Composed of two chains; the small (or glutamine)chain promotes the hydrolysis of glutamine to ammonia_which is used by the large (or ammonia) chain tosynthesize carbamoyl phosphate; Orthologue of BL0067; Belongs to the CarA family. (396 aa) |
| | carB | Carbamoyl-phosphate synthase large chain; Composed of two chains; the small (or glutamine)chain promotes the hydrolysis of glutamine to ammonia_which is used by the large (or ammonia) chain tosynthesize carbamoyl phosphate; binds manganese; involvedin pyrimidine synthesis; Orthologue of Rv1384_BL0068. (1126 aa) |
| | gmk | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (195 aa) |
| | metK | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (404 aa) |
| | priA | Probable primosomal protein N; Binding of PriA to forked DNA starts the assemblyof the primosome_ also posseses 3'-5' helicase activity; Orthologue of BL1791. (743 aa) |
| | arc | Probable Aaa-family ATPase; COG family: ATPases of the Aaa+ class; Orthologue of BL1794; PFAM_ID:AAA. (515 aa) |
| | pafA | Hypothetical proteasome-associated protein; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. (488 aa) |
| | BAD_0562 | Widely conserved MoxR-like protein in magnesium chelatase family; COG family: MoxR-like ATPases; Orthologue of BL1811; PFAM_ID: AAA; PFAM_ID: Mg_chelatase. (355 aa) |
| | groEL | groEL protein; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (538 aa) |
| | BAD_0572 | COG family: universal stress protein UspA andrelated nucleotide-binding proteins; Orthologue of BL0009; PFAM_ID: Usp. (354 aa) |
| | clpC1 | Orthologue of Rv3596c_BL0010; ProbableclpC1_ ATP-dependent protease ATP-binding subunit (EC3.4.-.-); Belongs to the ClpA/ClpB family. (864 aa) |
| | hisS | COG family:histidyl-tRNA synthetase; Histidine--tRNA ligase; Orthologue of BL0017; PFAM_ID: tRNA-synt_2b; PFAM_ID:HGTP_anticodon. (463 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (599 aa) |
| | BAD_0578 | Putative amino acid ABC transporter; ATP-binding protein; Orthologue of SMU.805c. (246 aa) |
| | gluA | ATP-binding protein of ABC transporter for glutamate; COG family: ABC-type polar amino acidtransport system_ ATPase component; Orthologue of BL0021; PFAM_ID: ABC_tran. (265 aa) |
| | BAD_0584 | Probable DEAD box-like helicase; Orthologue of Tfu_0878_BL0028. (852 aa) |
| | BAD_0585 | Hypothetical protein; COG family: uncharacterized ATPase related to thehelicase subunit of the holliday junction resolvase; Orthologue of BL0029; PFAM_ID: AAA. (466 aa) |
| | clpX | ATP-dependent specificity component of the Clp protease; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (473 aa) |
| | BAD_0595 | Hypothetical protein; COG family: predicted ATPase with chaperoneactivity; Orthologue of BL0936; PFAM_ID: Mg_chelatase. (509 aa) |
| | cbiO2 | ABC-type cobalt transport system, ATPase component; Orthologue of TTE1589. (541 aa) |
| | BAD_0603 | Possible ATP binding protein of ABC transporter; COG family: ABC-type transport systems_ involved inlipoprotein release_ ATPase components; Orthologue of BL0932; PFAM_ID: ABC_tran. (263 aa) |
| | ychF | Widely conserved hypothetical GTPase-like protein; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (366 aa) |
| | BAD_0611 | Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system. Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family. (655 aa) |
| | BAD_0623 | COG family: superfamily II DNA and RNA helicases; Identified by sequence similarity; Orthologue of BL0909; PFAM_ID: DEAD; PFAM_ID: helicase_C. (728 aa) |
| | BAD_0624 | Hypothetical protein; COG family: predicted permease; Orthologue of BL0063. (262 aa) |
| | BAD_0625 | COG family: ABC-type multidrug_protein_lipidtransport system_ ATPase component; Orthologue of BL0064; PFAM_ID: ABC_tran. (257 aa) |
| | mfd | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1188 aa) |
| | BAD_0656 | Hypothetical protein; COG family: DNA segregation ATPase FtsK_SpoIIIE andrelated proteins; Orthologue of BL1010; PFAM_ID: FtsK_SpoIIIE. (587 aa) |
| | troB | ATP binding protein of ABC transporter; COG family: ABC-typecobalamin_Fe3+-siderophores transport systems_ ATPasecomponents; Orthologue of BL0995; PFAM_ID: ABC_tran. (287 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (217 aa) |
| | uvrB | UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] (696 aa) |
| | pyk | COG family: pyruvate kinase; Orthologue of BL0988; PFAM_ID: PK; Belongs to the pyruvate kinase family. (505 aa) |
| | guaA | GMP synthase; Catalyzes the synthesis of GMP from XMP. (520 aa) |
| | ackA | Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (409 aa) |
| | uvrD1 | ATP-dependent DNA helicase PcrA; Orthologue of Rv0949_BL0890; ProbableuvrD1_ ATP dependent DNA helicase II (EC 3.6.1.-). (879 aa) |
| | BAD_0696 | COG family: ABC-type transport systems_ involved inlipoprotein release_ ATPase components; Orthologue of BL0887; PFAM_ID: ABC_tran. (271 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (892 aa) |
| | aroB | Bifunctional shikimate kinase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. (542 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (553 aa) |
| | BAD_0712 | Probable ATP binding protein of ABC transporter; COG family: iron-regulated ABC transporter ATPasesubunit SufC; Identified by sequence similarity; Orthologue of BL0870; PFAM_ID: ABC_tran. (259 aa) |
| | BAD_0715 | Hypothetical protein; COG family: putative aromatic ring hydroxylatingenzyme; Orthologue of BL0867; PFAM_ID: DUF59. (195 aa) |
| | glgC | Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (414 aa) |
| | BAD_0720 | PhoH-like protein; COG family: phosphate starvation-inducible proteinPhoH_ predicted ATPase; Orthologue of BL0862; PFAM_ID: PhoH. (377 aa) |
| | era | Widely conserved GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (332 aa) |
| | ispE | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (308 aa) |
| | BAD_0738 | COG family: ABC-type cobalt transport system_ATPase component; Orthologue of BL0693; PFAM_ID: ABC_tran; PFAM_ID: PRK. (515 aa) |
| | BAD_0740 | Excinuclease subunit A; Orthologue of BL1083_LBA1002; UvrA. (850 aa) |
| | lepA | GTP-binding protein lepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (579 aa) |
| | BAD_0752 | Probable ATP binding protein of ABC transporter; COG family: ABC-type molybdenum transport system_ATPase component_photorepair protein PhrA; Orthologue of BL0825; PFAM_ID:ABC_tran. (301 aa) |
| | glnE | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] (1036 aa) |
| | nnrE | Hypothetical protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Belongs to the NnrE/AIBP family. (591 aa) |
| | BAD_0772 | ABC transporter; ATP-binding protein; Orthologue of SP1653. (233 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (249 aa) |
| | hisE | phosphoribosyl-ATP pyrophosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMPfrom 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; Orthologue of BL0752. (98 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (283 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes a two-step reaction_ first charging athreonine molecule by linking its carboxyl group to thealpha-phosphate of ATP_ followed by transfer of theaminoacyl-adenylate to its tRNA; Orthologue of Rv2614c_BL0724; Belongs to the class-II aminoacyl-tRNA synthetase family. (711 aa) |
| | ruvA | Holliday junction ATP-dependent DNA helicase ruvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (205 aa) |
| | ruvB | Holliday junction ATP-dependent DNA helicase ruvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (362 aa) |
| | sucC | succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (395 aa) |
| | engA | GTP-binding protein engA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. (675 aa) |
| | BAD_0818 | Probable helicase; Identified by sequence similarity; Orthologue of Lxx08340_BL0742. (882 aa) |
| | dnaJ | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (383 aa) |
| | pgk | Phosphoglycerate kinase; Catalyzes the formation of 3-phospho-D-glyceroylphosphate from 3-phospho-D-glycerate; Orthologue of BL0707; Belongs to the phosphoglycerate kinase family. (401 aa) |
| | BAD_0837 | Hypothetical protein; Displays ATPase and GTPase activities. (310 aa) |
| | uvrA | Excinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (995 aa) |
| | BAD_0850 | Putative ABC transporter; COG0488_ Uup_ ATPase components of ABC transporterswith duplicated ATPase domains; Fused ATPase subunits; Orthologue of RSP_2895. (262 aa) |
| | BAD_0851 | ATP binding protein of ABC transporter; Orthologue of Tfu_1880_BL0689. (533 aa) |
| | BAD_0860 | Hypothetical protein; Orthologue of SAV4969; PF02367: Uncharacterised P-loop hydrolase UPF0079. (190 aa) |
| | leuS | leucyl-tRNA synthetase; Charges leucine bylinking carboxyl group to alpha-phosphate of ATP and thentransfers aminoacyl-adenylate to its tRNA; Orthologue of Rv0041_ BL1450; Belongs to the class-I aminoacyl-tRNA synthetase family. (990 aa) |
| | BAD_0879 | Insertion element conserved hypothetical protein; Orthologue of CE1245. (260 aa) |
| | BAD_0881 | Type III restriction enzyme; Orthologue of BB0913; Similar to Salmonella typhimurium type III restriction-modification system stylti enzyme res orstm0358 SWALL:T3RE_SALTY (SWALL:P40815). (233 aa) |
| | BAD_0892 | ATP binding protein of ABC transporter similar to Vex2; COG family: ABC-type transport systems_ involved inlipoprotein release_ ATPase components; Orthologue of BL0267; PFAM_ID: ABC_tran. (211 aa) |
| | prsA2 | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (339 aa) |
| | nadD | Possible nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (242 aa) |
| | recN | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (568 aa) |
| | ppnK | Probable inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (314 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (435 aa) |
| | argG | Argininosuccinate synthase; Orthologue of BL1058; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (418 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (318 aa) |
| | pheT | phenylalanyl-tRNA synthetase beta chain; Catalyzes a two-step reaction_ first charging aphenylalanine molecule by linking its carboxyl group tothe alpha-phosphate of ATP_ followed by transfer of theaminoacyl-adenylate to its tRNA; Orthologue of Tfu_2060_BL1066; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (867 aa) |
| | pheS | phenylalanyl-tRNA synthetase alpha chain; Catalyzes a two-step reaction_ first charging aphenylalanine molecule by linking its carboxyl group tothe alpha-phosphate of ATP_ followed by transfer of theaminoacyl-adenylate to its tRNA; forms a heterotetramer ofalpha(2)beta(2); binds two magnesium; Orthologue of BL1067; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (355 aa) |
| | BAD_0930 | Similar to transporter; Orthologue of lmo1506. (243 aa) |
| | BAD_0931 | ABC transporter domain protein; Identified by match to protein family HMM PF00005; Orthologue of BCE2757. (276 aa) |
| | glnA1 | Glutamine synthetase 1; Orthologue of jk0702_BL1076. (478 aa) |
| | BAD_0949 | COG family: ABC-type cobalt transport system_ATPase component; Orthologue of BL1070; PFAM_ID: ABC_tran. (497 aa) |
| | mrp | Hypothetical protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (373 aa) |
| | BAD_0955 | COG family: ABC-type cobalt transport system_ATPase component; Orthologue of BL0049; PFAM_ID: ABC_tran. (279 aa) |
| | cbiO | Cobalt import ATP-binding/permease protein cbiO; COG family: ABC-type cobalt transport system_permease component CbiQ and related transporters; Orthologue of BL0043; PFAM_ID: CbiQ; PFAM_ID:ABC_tran. (775 aa) |
| | BAD_0963 | Possible helicase; COG family: superfamily II DNA_RNA helicases_ Snf2family; Orthologue of BL1736; PFAM_ID: SNF2_N; PFAM_ID: helicase_C. (1279 aa) |
| | nadE | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (327 aa) |
| | BAD_0998 | D-methionine ABC transporter; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family. (274 aa) |
| | relA | Probable GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (770 aa) |
| | gyrA2 | DNA gyrase subunit A; Orthologue of Tfu_2131_BL1434; negatively supercoils closed circulardouble-stranded DNA. (891 aa) |
| | lhr | ATP-dependent helicase II; Orthologue of b1653_BL1432. (1625 aa) |
| | gyrB2 | COG family: DNA gyrase (topoisomerase II) Bsubunit; Orthologue of BL1429; PFAM_ID: DNA_gyraseB_C; PFAM_ID: DNA_topoisoII; PFAM_ID: HATPase_c. (774 aa) |
| | pknA2 | Probable serine-threonine protein kinase pknA2; COG family: serine_threonine proteinkinases; Orthologue of BL1425; PFAM_ID: pkinase. (732 aa) |
| | secA1 | Preprotein translocase SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (996 aa) |
| | recA | Protein recA (Recombinase A); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (394 aa) |
| | ftsK | DNA translocase ftsK; Orthologue of Tfu_0793_BL1411. (934 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (336 aa) |
| | BAD_1042 | Probable ATP binding protein of ABC transporter; COG family: ABC-type multidrug transport system_ATPase component; Orthologue of BL0901; PFAM_ID: ABC_tran. (350 aa) |
| | ctpE | Probable cation-transporting ATPase; COG family: cation transport ATPases; Orthologue of BL1396; PFAM_ID: E1-E2_ATPase; PFAM_ID: Hydrolase. (824 aa) |
| | dppD | Dipeptide transport ATP-binding protein; COG family: ATPase components of various ABC-typetransport systems_ contain duplicated ATPase; Orthologue of BL1390; PFAM_ID:ABC_tran; Belongs to the ABC transporter superfamily. (669 aa) |
| | dppC | Probable permease protein of ABC-transporter for peptides; COG family: ABC-typedipeptide_oligopeptide_nickel transport systems_ permeasecomponents; Orthologue of BL1389; PFAM_ID: BPD_transp. (322 aa) |
| | BAD_1064 | Putative ABC transporter ATP-binding protein; Orthologue of BL0932_nfa46550. (281 aa) |
| | BAD_1069 | Widely conserved protein similar to those annotated as GTP-binding elongation factor TypA/BipA; COG family: predicted membrane GTPase involved instress response; Orthologue of BL1379; PFAM_ID: GTP_EFTU. (643 aa) |
| | BAD_1072 | Hypothetical protein; COG family: ATPases involved in chromosomepartitioning; Orthologue of BL1370; PFAM_ID: ParA; PFAM_ID: fer4_NifH. (279 aa) |
| | asnH | Asparagine synthetase; Aspartate family; Orthologue of L0095. (628 aa) |
| | BAD_1078 | Hypothetical protein; Orthologue of BL1364. (248 aa) |
| | murE | UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Orthologue of BL1356; Belongs to the MurCDEF family. MurE subfamily. (517 aa) |
| | BAD_1086 | Hypothetical protein; Orthologue of LSA0098. (414 aa) |
| | folC | COG family: folylpolyglutamatesynthase; Orthologue of BL1353; PFAM_ID: Mur_ligase. (532 aa) |
| | dppD-2 | ATP binding protein of ABC transporter; Identified by sequence similarity; Orthologue of Lxx08560_BL1348; Belongs to the ABC transporter superfamily. (570 aa) |
| | BAD_1092 | Probable permease of ABC transporter for peptides; COG family: ABC-type dipeptide_oligopeptide_nickeltransport systems_ permease components; Orthologue of BL1347. (391 aa) |
| | murC | UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (521 aa) |
| | murD | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (479 aa) |
| | murF | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (489 aa) |
| | BAD_1106 | Hypothetical protein; COG family: UDP-N-acetylmuramyl tripeptidesynthase; Orthologue of BL1318. (285 aa) |
| | BAD_1111 | Hypothetical protein; Orthologue of BL1314. (765 aa) |
| | nrdR | Transcriptional repressor nrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (170 aa) |
| | hflX | GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. (498 aa) |
| | hrpA | ATP-dependent helicase; Orthologue of ECs2015_BL1305. (1369 aa) |
| | ftsZ | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (410 aa) |
| | glyS | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (491 aa) |
| | thiM | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (294 aa) |
| | BAD_1161 | COG family: predicted secreted protein containing aPDZ domain; Orthologue of BL0094. (298 aa) |
| | BAD_1163 | COG family: superfamily I DNA and RNAhelicases; Orthologue of BL0092; PFAM_ID: UvrD-helicase; UvrD. (499 aa) |
| | BAD_1178 | Insertion element conserved hypothetical protein; Orthologue of CE1245. (144 aa) |
| | cas3 | Predicted CRISPR-associated helicase; Orthologue of ebA3291_BH0336. (805 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1110 aa) |
| | BAD_1191 | ABC transporter; ATP-binding transmembrane protein; Orthologue of CAC3415_BL1767. (658 aa) |
| | BAD_1192 | ATP-binding protein of ABC transporter; COG family: ABC-type multidrug_protein_lipidtransport system_ ATPase component; Orthologue of BL1766; PFAM_ID: ABC_membrane; PFAM_ID: ABC_tran. (606 aa) |
| | BAD_1200 | Hypothetical protein; Orthologue of BLi00227. (395 aa) |
| | nrdD | Anaerobic ribonucleoside triphosphate reductase; Catalyzes the reduction of nucleoside5'-triphosphates to 2'-deoxynucleoside 5'-triphosphates; Orthologue of HI0075. (801 aa) |
| | BAD_1221 | Hypothetical protein; CE3P009_ similar to PIR:S76704 percent identity: 37in 153 aa; Orthologue of CE3P009. (196 aa) |
| | BAD_1227 | Putative helicase IV; Orthologue of YPO1440. (690 aa) |
| | BAD_1230 | Helicase; Orthologue of BCE1021; SNF2 family. (890 aa) |
| | BAD_1248 | Hypothetical protein; COG family: ATP-dependent Lon protease_ bacterialtype; Orthologue of BL1483. (499 aa) |
| | yckI | Similar to glutamine ABC transporter (ATP-binding protein); Orthologue of BLi00418. (255 aa) |
| | BAD_1273 | Hypothetical protein; Orthologue of CE3P009. (199 aa) |
| | BAD_1280 | Type II restriction-modification systemrestriction subunit; Orthologue of BC0939. (167 aa) |
| | BAD_1285 | Hypothetical protein; Identified by Glimmer2; putative; Orthologue of SERP2454. (326 aa) |
| | actP | ActP copper transport ATPase; Orthologue of SMa1013; Silver efflux P-type ATPase [Psychrobacter arcticus 273-4]; Start changed for RBS and homology with other ATPases. (1000 aa) |
| | BAD_1305 | Widely conserved ATP-dependent DNA helicase; COG family: superfamily I DNA and RNA helicases; Orthologue of BL1196; PFAM_ID:UvrD-helicase; Belongs to the helicase family. UvrD subfamily. (1356 aa) |
| | BAD_1306 | Hypothetical protein; COG family: superfamily I DNA and RNA helicases; Orthologue of BL1197. (1065 aa) |
| | BAD_1310 | COG family: serine_threonine protein kinases; PFAM_ID: pkinase. (473 aa) |
| | moxR | Methanol dehydrogenase regulatory protein homolog; COG family: MoxR-like ATPases; Orthologue of BL1199a; PFAM_ID:Mg_chelatase. (449 aa) |
| | galK | COG family: galactokinase; Orthologue of BL1210; PFAM_ID: GHMP_kinases; Belongs to the GHMP kinase family. GalK subfamily. (416 aa) |
| | BAD_1354 | Hypothetical protein; Orthologue of BL1511. (356 aa) |
| | BAD_1358 | Possible Etk-like tyrosine kinase involved in Eps biosynthesis; COG family: ATPases involved in chromosomepartitioning; Orthologue of BL1229. (498 aa) |
| | BAD_1376 | Insertion element conserved hypothetical protein; Orthologue of CE1245. (234 aa) |
| | BAD_1392 | Bacterial regulatory protein; Orthologue of cg0150. (414 aa) |
| | BAD_1408 | COG family: ABC-type multidrug_protein_lipidtransport system_ ATPase component; Orthologue of BL0264; PFAM_ID: ABC_membrane; PFAM_ID: ABC_tran. (1342 aa) |
| | thrB | Possible homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (334 aa) |
| | argS | arginyl-tRNA synthetase; Catalyzes a two-step reaction_ first charging anarginine molecule by linking its carboxyl group to thealpha-phosphate of ATP_ followed by transfer of theaminoacyl-adenylate to its tRNA; Orthologue of BL1272. (596 aa) |
| | atpD | ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (494 aa) |
| | atpG | ATP synthase gamma chain; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (306 aa) |
| | atpA | ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (542 aa) |
| | BAD_1436 | ABC transporter; ATP-binding protein; Identified by match to protein family HMM PF00005; Orthologue of LMOf2365_2627. (226 aa) |
| | valS | Valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner. (924 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (670 aa) |
| | gatB | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (498 aa) |
| | gatA | glutamyl-tRNA(Gln) amidotransferase subunit A; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (511 aa) |
| | gatC | aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (98 aa) |
| | silP | COG family: cation transport ATPases; Orthologue of BL0409; PFAM_ID: E1-E2_ATPase; PFAM_ID: Hydrolase. (311 aa) |
| | clpB | Chaperone clpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (905 aa) |
| | clfA | Truncated clumping factor; Orthologue of SAB0744. (431 aa) |
| | gluQ | glutamyl-Q tRNA(Asp) synthetase; COG family:glutamyl- and glutaminyl-tRNA synthetases; Glutamate--tRNA ligase; Orthologue of BL1251; PFAM_ID:tRNA-synt_1c; Belongs to the class-I aminoacyl-tRNA synthetase family. (413 aa) |
| | rbsK | Sugar kinase in PfkB family; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (330 aa) |
| | BAD_1488 | Hypothetical protein. (85 aa) |
| | BAD_1489 | ATPase; Orthologue of FN1382. (115 aa) |
| | rgpDc | Protein possibly involved in ATP-driven polysaccharide export; COG family: ABC-type polysaccharide_polyolphosphate transport system_ ATPase component; Orthologue of BL0207; PFAM_ID:ABC_tran. (408 aa) |
| | BAD_1519 | Possible ATP binding protein of ABC transporter; COG family: ABC-type sugar (aldose) transportsystem_ ATPase component; COG family: ABC-type transport systems_ involved inlipoprotein release_ permease components; Orthologue of BL0197; PFAM_ID: ABC_tran. (347 aa) |
| | BAD_1530 | Similar to ABC transporter; ATP-binding protein; Orthologue of BL0180_lin0155. (595 aa) |
| | BAD_1531 | COG family: ABC-type multidrug_protein_lipidtransport system_ ATPase component; Orthologue of BL0179; PFAM_ID: ABC_membrane; PFAM_ID: ABC_tran. (630 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (620 aa) |
| | dnaK | Chaperone protein dnaK (Heat shock protein 70); Acts as a chaperone; Belongs to the heat shock protein 70 family. (626 aa) |
| | BAD_1581 | Calcium-transporting ATPase; Orthologue of ABC2324. (1024 aa) |
| | BAD_1592 | Hypothetical protein; Orthologue of BL0679. (470 aa) |
| | msiK-2 | ATP binding protein of ABC transporter for sugars; COG family: ABC-typesugar_spermidine_putrescine_iron_thiamine transportsystems_ ATPase component; Orthologue of BL0673; PFAM_ID: ABC_tran; Belongs to the ABC transporter superfamily. (375 aa) |
