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rpl10 rpl10 rpl1 rpl1 rpl11 rpl11 rps19 rps19 rpl2 rpl2 rpl23 rpl23 rpl4 rpl4 rpl3 rpl3 rpl15 rpl15 rpl30 rpl30 rps5 rps5 rpl18 rpl18 rpl19e rpl19e rpl32e rpl32e rps8 rps8 rps14 rps14 rpl5 rpl5 rps4e rps4e rpl24 rpl24 rps11 rps11 rps4 rps4 rps13 rps13 rps7 rps7 rps2 rps2 rps9 rps9 rpl13 rpl13 rpl18e rpl18e rps12 rps12 rpl30e rpl30e rpl40e rpl40e rpl35ae rpl35ae rps17e rps17e rpl21e rpl21e rps8e rps8e Tpen_0390 Tpen_0390 rpl37e rpl37e rps6e rps6e rpl18a rpl18a rps24e rps24e rpl14e rpl14e rps19e rps19e rpl39e rpl39e rpl31e rpl31e rpl14 rpl14 rps17 rps17 rpl29 rpl29 rpl22 rpl22 rpl37ae rpl37ae infB infB rpl24e rpl24e rps15 rps15 rpl10e rpl10e Tpen_0548 Tpen_0548 rpl6 rpl6 fusA fusA rpl34e rpl34e rpl44e rpl44e tuf tuf rps10 rps10 rps3ae rps3ae ef1b ef1b map map rpl13e rpl13e gltX gltX proS proS Tpen_0824 Tpen_0824 rpl12 rpl12 Tpen_1016 Tpen_1016
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rpl10LSU ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (294 aa)
rpl1LSU ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (225 aa)
rpl11LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (168 aa)
rps19SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (141 aa)
rpl2LSU ribosomal protein L2P; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (248 aa)
rpl23LSU ribosomal protein L23P; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (90 aa)
rpl4LSU ribosomal protein L4P; Forms part of the polypeptide exit tunnel. (267 aa)
rpl3LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (334 aa)
rpl15LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (151 aa)
rpl30TIGRFAM: ribosomal protein L30P; PFAM: ribosomal protein L30; KEGG: neq:NEQ311 LSU ribosomal protein L30P. (156 aa)
rps5SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (202 aa)
rpl18LSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (196 aa)
rpl19eLSU ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (155 aa)
rpl32ePFAM: Ribosomal protein L32e; KEGG: pai:PAE2099 ribosomal protein L32; Belongs to the eukaryotic ribosomal protein eL32 family. (159 aa)
rps8SSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (129 aa)
rps14SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (54 aa)
rpl5LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (182 aa)
rps4ePFAM: RNA-binding S4 domain protein; Ribosomal protein S4E-like; Ribosomal protein S4E, central; KEGG: ape:APE0356 30S ribosomal protein S4e; Belongs to the eukaryotic ribosomal protein eS4 family. (251 aa)
rpl24LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (131 aa)
rps11SSU ribosomal protein S11P; Located on the platform of the 30S subunit. Belongs to the universal ribosomal protein uS11 family. (156 aa)
rps4SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (172 aa)
rps13SSU ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (157 aa)
rps7SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (200 aa)
rps2PFAM: ribosomal protein S2; KEGG: pai:PAE0817 ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (214 aa)
rps9PFAM: ribosomal protein S9; KEGG: afu:AF1129 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (132 aa)
rpl13LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (154 aa)
rpl18eKEGG: tko:TK1502 LSU ribosomal protein L18E; Belongs to the eukaryotic ribosomal protein eL18 family. (120 aa)
rps12SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (147 aa)
rpl30ePFAM: ribosomal protein L7Ae/L30e/S12e/Gadd45; KEGG: pab:PAB7152 50S ribosomal protein L30e; Belongs to the eukaryotic ribosomal protein eL30 family. (104 aa)
rpl40ePFAM: Ribosomal protein L40e; KEGG: pai:PAE3255 ribosomal protein L40; Belongs to the eukaryotic ribosomal protein eL40 family. (51 aa)
rpl35aePFAM: Ribosomal protein L35Ae; KEGG: mka:MK0155 ribosomal protein L35AE/L33A; Belongs to the eukaryotic ribosomal protein eL33 family. (85 aa)
rps17ePFAM: Ribosomal protein S17e; KEGG: pai:PAE0804 ribosomal protein S17; Belongs to the eukaryotic ribosomal protein eS17 family. (95 aa)
rpl21ePFAM: ribosomal protein L21e; KEGG: pai:PAE3334 ribosomal protein L21; Belongs to the eukaryotic ribosomal protein eL21 family. (102 aa)
rps8eTIGRFAM: ribosomal protein S8e; PFAM: ribosomal protein S8E; KEGG: neq:NEQ469 SSU ribosomal protein S8E. (128 aa)
Tpen_0390PFAM: Ribosomal protein L15e; KEGG: ape:APE1452 50S ribosomal protein L15e. (187 aa)
rpl37eLSU ribosomal protein L37E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL37 family. (63 aa)
rps6ePFAM: ribosomal protein S6e; KEGG: mka:MK1446 ribosomal protein S6E (S10); Belongs to the eukaryotic ribosomal protein eS6 family. (131 aa)
rpl18aPFAM: Ribosomal LX protein; KEGG: ape:APE1084a S ribosomal protein LX. (85 aa)
rps24ePFAM: Ribosomal protein S24e; KEGG: sso:SSO0435 30S ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. (106 aa)
rpl14eKEGG: sto:STS054 50S ribosomal protein L14e; Belongs to the eukaryotic ribosomal protein eL14 family. (98 aa)
rps19eSSU ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (163 aa)
rpl39ePFAM: ribosomal protein L39e; KEGG: mka:MK1618 ribosomal protein L39E; Belongs to the eukaryotic ribosomal protein eL39 family. (50 aa)
rpl31ePFAM: Ribosomal protein L31e; KEGG: pai:PAE3095 ribosomal protein L31; Belongs to the ribosomal protein L31e family. (103 aa)
rpl14LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (141 aa)
rps17SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (111 aa)
rpl29PFAM: ribosomal protein L29; KEGG: sso:SSO6397 50S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (84 aa)
rpl22LSU ribosomal protein L22P; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (127 aa)
rpl37aeLSU ribosomal protein L37AE; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily. (91 aa)
infBTranslation initiation factor aIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (601 aa)
rpl24eLSU ribosomal protein L24E; Binds to the 23S rRNA. (63 aa)
rps15PFAM: ribosomal protein S15; Ribosomal S13S15-like; KEGG: mka:MK1593 ribosomal protein S15P/S13E. (148 aa)
rpl10ePFAM: Ribosomal protein L10E; KEGG: pai:PAE3567 ribosomal protein L10; Belongs to the universal ribosomal protein uL16 family. (168 aa)
Tpen_0548KEGG: sai:Saci_1554 30S ribosomal protein S26E. (97 aa)
rpl6LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (191 aa)
fusATranslation elongation factor 2 (EF-2/EF-G); Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. [...] (734 aa)
rpl34ePFAM: Ribosomal protein L34e; KEGG: mja:MJ0655 50S ribosomal protein L34e; Belongs to the eukaryotic ribosomal protein eL34 family. (91 aa)
rpl44eLSU ribosomal protein L44E; Binds to the 23S rRNA. (95 aa)
tufTranslation elongation factor 1A (EF-1A/EF-Tu); This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (433 aa)
rps10SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (109 aa)
rps3aePFAM: ribosomal protein S3Ae; KEGG: pfu:PF2054 30S ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family. (207 aa)
ef1bTranslation elongation factor 1B (aEF-1B); Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (91 aa)
mapMethionine aminopeptidase, type II; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily. (303 aa)
rpl13eKEGG: pai:PAE1639 ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. (157 aa)
gltXglutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu). (569 aa)
proSprolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (482 aa)
Tpen_0824Ras superfamily GTP-binding protein YlqF; PFAM: GTP-binding protein, HSR1-related; KEGG: pai:PAE0759 GTP binding protein, conjectural; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (261 aa)
rpl12LSU ribosomal protein L12AE; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (108 aa)
Tpen_1016KEGG: pai:PAE2188 small subunit ribosomal protein S25e. (112 aa)
Your Current Organism:
Thermofilum pendens
NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5
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