(6 nodes) Large ribosomal subunit, and GTP binding domain network (Thermofilum pendens)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	rpl3	LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (334 aa)
	rpl15	LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (151 aa)
	rpl24	LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (131 aa)
	rpl13	LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (154 aa)
	rpl14	LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (141 aa)
	Tpen_0824	Ras superfamily GTP-binding protein YlqF; PFAM: GTP-binding protein, HSR1-related; KEGG: pai:PAE0759 GTP binding protein, conjectural; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (261 aa)

Your Current Organism:

Thermofilum pendens

NCBI taxonomy Id: 368408
Other names: T. pendens Hrk 5, Thermofilum pendens Hrk 5, Thermofilum pendens str. Hrk 5, Thermofilum pendens strain Hrk 5

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Tpen_0824	rpl13	Tpen_0824	Tpen_0278	Ras superfamily GTP-binding protein YlqF; PFAM: GTP-binding protein, HSR1-related; KEGG: pai:PAE0759 GTP binding protein, conjectural; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.	LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.999
Tpen_0824	rpl14	Tpen_0824	Tpen_0483	Ras superfamily GTP-binding protein YlqF; PFAM: GTP-binding protein, HSR1-related; KEGG: pai:PAE0759 GTP binding protein, conjectural; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.	LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	0.999
Tpen_0824	rpl15	Tpen_0824	Tpen_0234	Ras superfamily GTP-binding protein YlqF; PFAM: GTP-binding protein, HSR1-related; KEGG: pai:PAE0759 GTP binding protein, conjectural; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.	LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.999
Tpen_0824	rpl24	Tpen_0824	Tpen_0244	Ras superfamily GTP-binding protein YlqF; PFAM: GTP-binding protein, HSR1-related; KEGG: pai:PAE0759 GTP binding protein, conjectural; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.	LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	0.999
Tpen_0824	rpl3	Tpen_0824	Tpen_0230	Ras superfamily GTP-binding protein YlqF; PFAM: GTP-binding protein, HSR1-related; KEGG: pai:PAE0759 GTP binding protein, conjectural; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.	LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.999
rpl13	Tpen_0824	Tpen_0278	Tpen_0824	LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	Ras superfamily GTP-binding protein YlqF; PFAM: GTP-binding protein, HSR1-related; KEGG: pai:PAE0759 GTP binding protein, conjectural; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.	0.999
rpl13	rpl14	Tpen_0278	Tpen_0483	LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	0.999
rpl13	rpl15	Tpen_0278	Tpen_0234	LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.999
rpl13	rpl24	Tpen_0278	Tpen_0244	LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	0.999
rpl13	rpl3	Tpen_0278	Tpen_0230	LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.999
rpl14	Tpen_0824	Tpen_0483	Tpen_0824	LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	Ras superfamily GTP-binding protein YlqF; PFAM: GTP-binding protein, HSR1-related; KEGG: pai:PAE0759 GTP binding protein, conjectural; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.	0.999
rpl14	rpl13	Tpen_0483	Tpen_0278	LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.999
rpl14	rpl15	Tpen_0483	Tpen_0234	LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	0.999
rpl14	rpl24	Tpen_0483	Tpen_0244	LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	0.999
rpl14	rpl3	Tpen_0483	Tpen_0230	LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.999
rpl15	Tpen_0824	Tpen_0234	Tpen_0824	LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	Ras superfamily GTP-binding protein YlqF; PFAM: GTP-binding protein, HSR1-related; KEGG: pai:PAE0759 GTP binding protein, conjectural; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily.	0.999
rpl15	rpl13	Tpen_0234	Tpen_0278	LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	LSU ribosomal protein L13P; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.	0.999
rpl15	rpl14	Tpen_0234	Tpen_0483	LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family.	0.999
rpl15	rpl24	Tpen_0234	Tpen_0244	LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.	0.999
rpl15	rpl3	Tpen_0234	Tpen_0230	LSU ribosomal protein L15P; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family.	LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.	0.999