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| | rpl18a | PFAM: Ribosomal LX protein; KEGG: ape:APE1084a S ribosomal protein LX. (85 aa) |
| | Tpen_1826 | Glycosyltransferases probably involved in cell wall biogenesis-like protein; KEGG: sai:Saci_1499 conserved membrane glocosyltransferase. (480 aa) |
| | Tpen_1821 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: pho:PH1901 3-oxoacyl-[acyl-carrier protein] reductase. (264 aa) |
| | Tpen_1812 | PFAM: DEAD_2 domain protein; SMART: DEXDc2; helicase c2; KEGG: tko:TK0784 ERCC2/XPD/Rad3-related DNA repair helicase. (617 aa) |
| | Tpen_1802 | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: ace:Acel_0523 FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (392 aa) |
| | Tpen_1763 | PFAM: protein of unknown function DUF134; sigma-70 region 4 domain protein; KEGG: tko:TK0562 hypothetical protein; Belongs to the UPF0251 family. (116 aa) |
| | Tpen_1762 | DNA repair helicase RAD25; PFAM: helicase domain protein; type III restriction enzyme, res subunit; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: pho:PH0450 hypothetical protein. (451 aa) |
| | Tpen_1760 | PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: tko:TK0703 hypothetical protein. (323 aa) |
| | Tpen_1750 | PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase; KEGG: lic:LIC20037 methanol dehydrogenase regulator. (353 aa) |
| | Tpen_1730 | PFAM: glycosyl transferase, family 2; KEGG: sto:ST2332 hypothetical protein. (420 aa) |
| | Tpen_1684 | TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: dvu:DVU1778 cation efflux family protein. (450 aa) |
| | Tpen_1655 | KEGG: pfu:PF1192 hypothetical protein. (96 aa) |
| | Tpen_1650 | PFAM: protein of unknown function DUF125, transmembrane; KEGG: ape:APE1814 hypothetical protein. (290 aa) |
| | Tpen_1604 | SMART: ParB domain protein nuclease; KEGG: ape:APE0702 hypothetical protein. (168 aa) |
| | Tpen_1584 | PFAM: ATPase; KEGG: pab:PAB1370 hypothetical protein. (356 aa) |
| | Tpen_1574 | PFAM: SMC domain protein; KEGG: rxy:Rxyl_0448 SMC protein-like protein. (840 aa) |
| | Tpen_1573 | PFAM: metallophosphoesterase; KEGG: gsu:GSU1421 nuclease SbcCD, D subunit, putative. (391 aa) |
| | Tpen_1564 | TIGRFAM: anion transporter; PFAM: sodium/sulphate symporter; Citrate transporter; KEGG: hso:HS_1663 possible permease. (493 aa) |
| | Tpen_1533 | PFAM: Citrate transporter; KEGG: pai:PAE2457 arsenite transport protein, conjectural. (452 aa) |
| | pckG | Phosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle. (636 aa) |
| | Tpen_1531 | PFAM: SufBD protein; KEGG: mba:Mbar_A1079 hypothetical protein. (406 aa) |
| | Tpen_1528 | PFAM: peptidase S1 and S6, chymotrypsin/Hap; PDZ/DHR/GLGF domain protein; KEGG: mta:Moth_0736 peptidase S1 and S6, chymotrypsin/Hap. (311 aa) |
| | Tpen_1519 | PFAM: Dinitrogenase iron-molybdenum cofactor biosynthesis; KEGG: pho:PH1227 hypothetical protein. (107 aa) |
| | Tpen_1497 | PFAM: peptidase U34, dipeptidase; KEGG: pae:PA4677 hypothetical protein. (437 aa) |
| | Tpen_1450 | PFAM: phosphatidate cytidylyltransferase; KEGG: mba:Mbar_A1936 integral membrane protein. (197 aa) |
| | Tpen_1449 | Geranylgeranylglycerol-phosphate geranylgeranyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids. (284 aa) |
| | Tpen_1430 | Redoxin domain protein; PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: sto:ST2102 hypothetical thioredoxin peroxidase. (156 aa) |
| | Tpen_1428 | PFAM: cytochrome c biogenesis protein, transmembrane region; KEGG: ape:APE2273 hypothetical protein. (440 aa) |
| | Tpen_1427 | KEGG: lca:LSEI_0125 cation transport ATPase; TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; plasma-membrane proton-efflux P-type ATPase; PFAM: cation transporting ATPase domain protein domain protein; Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein. (802 aa) |
| | Tpen_1350 | TIGRFAM: amidohydrolase; PFAM: peptidase M20; peptidase dimerisation domain protein; KEGG: sus:Acid_2231 amidohydrolase. (473 aa) |
| | Tpen_1267 | PFAM: ATPase; KEGG: sai:Saci_1080 conserved archaeal protein. (342 aa) |
| | Tpen_1261 | PFAM: Alba, DNA/RNA-binding protein; KEGG: sai:Saci_1322 DNA binding protein alba-2. (95 aa) |
| | Tpen_1239 | PFAM: protein of unknown function DUF125, transmembrane. (279 aa) |
| | Tpen_1233 | PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: tko:TK0110 hydrolase, HAD superfamily. (237 aa) |
| | rbcL | Ribulose-1,5-bisphosphate carboxylase/oxygenase large subunit; Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase. Belongs to the RuBisCO large chain family. Type III subfamily. (443 aa) |
| | Tpen_1207 | PFAM: SufBD protein; KEGG: pfu:PF1285 hypothetical protein. (364 aa) |
| | Tpen_1206 | TIGRFAM: FeS assembly protein SufB; PFAM: SufBD protein; KEGG: pfu:PF1286 hypothetical protein. (470 aa) |
| | Tpen_1203 | Citrate transporter; PFAM: Arsenical pump membrane protein; Citrate transporter; KEGG: mmc:Mmcs_0587 citrate transporter. (465 aa) |
| | Tpen_1199 | TIGRFAM: geranylgeranyl reductase; PFAM: glucose-inhibited division protein A; monooxygenase, FAD-binding; HI0933 family protein; FAD dependent oxidoreductase; Lycopene beta and epsilon cyclase; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mta:Moth_0808 geranylgeranyl reductase. (423 aa) |
| | Tpen_1195 | PFAM: LmbE family protein; KEGG: pfu:PF0354 hypothetical protein. (270 aa) |
| | Tpen_1193 | Predicted alanyl-tRNA synthetase-like metal-dependent hydrolase; PFAM: Threonyl/alanyl tRNA synthetase, SAD; KEGG: sso:SSO0450 alanyl-tRNA synthetase truncated homolog (AlaS-like1). (252 aa) |
| | Tpen_1166 | KEGG: pai:PAE1503 hypothetical protein. (120 aa) |
| | Tpen_1160 | Dihydroorotate oxidase B, electron transfer subunit; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: mja:MJ1446 dihydroorotate dehydrogenase electron transfer subunit. (266 aa) |
| | Tpen_1147 | TIGRFAM: orotidine 5'-phosphate decarboxylase; PFAM: Orotidine 5'-phosphate decarboxylase; KEGG: mka:MK0735 orotidine-5'-phosphate decarboxylase. (229 aa) |
| | Tpen_1146 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: mtp:Mthe_0628 HAD-superfamily hydrolase, subfamily IA, variant 1. (233 aa) |
| | Tpen_1139 | Ferredoxin-dependent glutamate synthase; PFAM: FMN-dependent alpha-hydroxy acid dehydrogenase; ferredoxin-dependent glutamate synthase; KEGG: mth:MTH105 glutamate synthase (NADPH) alpha chain. (463 aa) |
| | Tpen_1133 | PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: pho:PH1996 hypothetical protein. (237 aa) |
| | Tpen_1130 | ATPase; KEGG: tko:TK2222 archaeal ATPase. (421 aa) |
| | Tpen_1126 | KEGG: pai:PAE0717 succinate dehydrogenase iron-sulfur subunit; TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin. (219 aa) |
| | Tpen_1119 | TIGRFAM: cation diffusion facilitator family transporter; PFAM: cation efflux protein; KEGG: mta:Moth_1683 cation diffusion facilitator family transporter. (275 aa) |
| | Tpen_1088 | NADH dehydrogenase (quinone); PFAM: NADH/Ubiquinone/plastoquinone (complex I); KEGG: ape:APE1410 NADH dehydrogenase I chain N. (456 aa) |
| | Tpen_1068 | PFAM: GCN5-related N-acetyltransferase; KEGG: pau:PA14_20491 putatative acetyltransferase. (109 aa) |
| | Tpen_1066 | PFAM: ParB domain protein nuclease; KEGG: ape:APE0702 hypothetical protein. (153 aa) |
| | Tpen_1036 | KEGG: sai:Saci_0991 hypothetical protein. (297 aa) |
| | Tpen_1030 | Ala-tRNA(Pro) hydrolase; PFAM: Threonyl/alanyl tRNA synthetase, SAD; KEGG: ape:APE0903 alanyl-tRNA synthetase. (240 aa) |
| | Tpen_1023 | Rad51-like protein; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. (315 aa) |
| | radA | DNA repair and recombination protein RadA; Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules. (358 aa) |
| | Tpen_1016 | KEGG: pai:PAE2188 small subunit ribosomal protein S25e. (112 aa) |
| | Tpen_1009 | PFAM: histidine triad (HIT) protein; KEGG: ape:APE2495 histidine triad (HIT) protein. (139 aa) |
| | Tpen_1006 | PFAM: iron-containing alcohol dehydrogenase; KEGG: tma:TM0920 alcohol dehydrogenase, iron-containing. (377 aa) |
| | Tpen_1000 | KEGG: pai:PAE1251 hypothetical protein. (342 aa) |
| | Tpen_0995 | KEGG: pho:PH1227 hypothetical protein. (121 aa) |
| | Tpen_0985 | PFAM: SNF2-related protein; helicase domain protein; type III restriction enzyme, res subunit; SMART: DEAD-like helicases-like; KEGG: pfu:PF0564 ATP-dependent RNA helicase hepa, putative. (813 aa) |
| | Tpen_0952 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 3; HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: ttj:TTHA1518 2-haloalkanoic acid dehalogenase-related protein. (242 aa) |
| | Tpen_0927 | TIGRFAM: hydroxymethylglutaryl-CoA reductase, degradative; KEGG: afu:AF1736 3-hydroxy-3-methylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family. (428 aa) |
| | Tpen_0903 | Hypothetical protein. (296 aa) |
| | Tpen_0883 | Endonuclease IV; PFAM: Xylose isomerase domain protein TIM barrel; SMART: AP endonuclease, family 2; KEGG: tko:TK0170 endonuclease IV. (291 aa) |
| | rpl12 | LSU ribosomal protein L12AE; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (108 aa) |
| | Tpen_0871 | ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication. (390 aa) |
| | Tpen_0863 | Putative phage repressor; TIGRFAM: peptidase S26B, signal peptidase; PFAM: peptidase S24, S26A and S26B; KEGG: ape:APE1796 signal peptidase I. (281 aa) |
| | Tpen_0861 | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: pai:PAE2298 ATP-dependent helicase. (744 aa) |
| | taw1 | Wyosine base formation; Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe). (358 aa) |
| | Tpen_0841 | Asparaginase; PFAM: peptidase T2, asparaginase 2; KEGG: pai:PAE3083 asparaginase. (319 aa) |
| | Tpen_0840 | PFAM: Auxin Efflux Carrier; KEGG: mka:MK1560 predicted permease. (293 aa) |
| | Tpen_0832 | PFAM: band 7 protein; KEGG: pho:PH0470 membrane protein. (289 aa) |
| | Tpen_0829 | PFAM: protein of unknown function DUF92, transmembrane; KEGG: osa:4324045 Os01g0507300. (273 aa) |
| | Tpen_0824 | Ras superfamily GTP-binding protein YlqF; PFAM: GTP-binding protein, HSR1-related; KEGG: pai:PAE0759 GTP binding protein, conjectural; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. (261 aa) |
| | Tpen_0819 | PFAM: beta-lactamase domain protein; KEGG: pto:PTO0275 metal dependent hydrolase. (256 aa) |
| | Tpen_0811 | Hypothetical protein. (113 aa) |
| | Tpen_0809 | Methyltransferase; PFAM: protein of unknown function Met10; KEGG: pai:PAE1486 hypothetical protein. (283 aa) |
| | Tpen_0795 | PFAM: cytochrome c biogenesis protein, transmembrane region; KEGG: pab:PAB0674 hypothetical protein. (927 aa) |
| | Tpen_0792 | Starch synthase; PFAM: glycosyl transferase, group 1; Starch synthase catalytic domain protein; KEGG: sai:Saci_1201 glycosyl transferase. (553 aa) |
| | Tpen_0788 | PFAM: chemotaxis sensory transducer; KEGG: pai:PAE1451 hypothetical protein. (529 aa) |
| | Tpen_0783 | PFAM: monooxygenase, FAD-binding; KEGG: afu:AF1023 bacteriochlorophyll synthase, 43 kDa subunit (ChlP-2). (375 aa) |
| | Tpen_0766 | PFAM: protein of unknown function DUF35; KEGG: pab:PAB0908 AcaC protein. (135 aa) |
| | Tpen_0764 | TIGRFAM: putative hydroxymethylglutaryl-CoA synthase; PFAM: Hydroxymethylglutaryl-coenzyme A synthase, N-terminal domain; 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal domain protein; KEGG: pfu:PF0972 3-oxoacyl-[acyl-carrier-protein] synthase III; Belongs to the thiolase-like superfamily. UPF0219 family. (346 aa) |
| | Tpen_0759 | KEGG: pai:PAE0627 hypothetical protein. (233 aa) |
| | lig2 | DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (601 aa) |
| | Tpen_0749 | KEGG: pai:PAE0831 hypothetical protein. (270 aa) |
| | Tpen_0748 | PFAM: AMMECR1 domain protein; KEGG: tko:TK0174 hypothetical protein. (213 aa) |
| | Tpen_0743 | PFAM: Rad51-like; SMART: AAA ATPase; KEGG: pai:PAE0654 DNA repair protein radA. (250 aa) |
| | rpl13e | KEGG: pai:PAE1639 ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family. (157 aa) |
| | Tpen_0728 | SMART: helicase c2. (471 aa) |
| | Tpen_0718 | TIGRFAM: geranylgeranyl reductase; PFAM: monooxygenase, FAD-binding; HI0933 family protein; FAD dependent oxidoreductase; KEGG: pab:PAB0109 bacteriochlorophyll synthase or geranylgeranyl hydrogenase. (387 aa) |
| | tfe | Transcription factor IIE (TFIIE), alpha subunit; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elo [...] (178 aa) |
| | Tpen_0707 | Transcriptional regulator, XRE family; PFAM: helix-turn-helix domain protein; KEGG: mth:MTH729 putative transcription factor. (134 aa) |
| | rnz | Ribonuclease Z; Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA; Belongs to the RNase Z family. (316 aa) |
| | tmcA | Protein of unknown function DUF699, ATPase putative; Catalyzes the formation of N(4)-acetylcytidine (ac(4)C) at the wobble position of tRNA(Met), by using acetyl-CoA as an acetyl donor and ATP (or GTP). (801 aa) |
| | top6A | Spo11/DNA topoisomerase; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family. (379 aa) |
| | Tpen_0654 | PFAM: phosphoesterase, RecJ domain protein; phosphoesterase, DHHA1; KEGG: ape:APE1437 hypothetical protein. (330 aa) |
| | rps3ae | PFAM: ribosomal protein S3Ae; KEGG: pfu:PF2054 30S ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family. (207 aa) |
| | Tpen_0652 | PFAM: helicase domain protein; type III restriction enzyme, res subunit; SMART: DEAD-like helicases-like; KEGG: pai:PAE1611 helicase, possible DNA repair rad25. (630 aa) |
| | Tpen_0649 | TIGRFAM: ZPR1-like zinc finger protein; ZPR1-related zinc finger protein; PFAM: Zinc finger, ZPR1-type; KEGG: pab:PAB1684 hypothetical protein. (200 aa) |
| | rps10 | SSU ribosomal protein S10P; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (109 aa) |
| | rpl44e | LSU ribosomal protein L44E; Binds to the 23S rRNA. (95 aa) |
| | Tpen_0640 | PFAM: Oligosaccharyl transferase, STT3 subunit; KEGG: pai:PAE3030 oligosaccharyl transferase STT3 homolog. (731 aa) |
| | Tpen_0638 | Hypothetical protein. (210 aa) |
| | Tpen_0636 | Geranylgeranylglycerol-phosphate geranylgeranyltransferase; PFAM: UbiA prenyltransferase; KEGG: afu:AF0404 4-hydroxybenzoate octaprenyltransferase. (277 aa) |
| | Tpen_0630 | PFAM: nucleic acid binding, OB-fold, tRNA/helicase-type; KEGG: mja:MJ1159 replication factor A related protein. (486 aa) |
| | rpl34e | PFAM: Ribosomal protein L34e; KEGG: mja:MJ0655 50S ribosomal protein L34e; Belongs to the eukaryotic ribosomal protein eL34 family. (91 aa) |
| | priL | DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. (356 aa) |
| | priS | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] (389 aa) |
| | Tpen_0621 | PFAM: beta-lactamase domain protein; KEGG: pai:PAE3418 putative mRNA 3-end processing factor. (317 aa) |
| | Tpen_0619 | TIGRFAM: tRNA intron endonuclease; PFAM: tRNA intron endonuclease, catalytic-like; KEGG: ape:APE1646 tRNA intron endonuclease. (171 aa) |
| | Tpen_0616 | KEGG: sto:ST0515 hypothetical protein; TIGRFAM: RNA modification enzyme, MiaB family; MiaB-like tRNA modifying enzyme; PFAM: deoxyribonuclease/rho motif-related TRAM; Radical SAM domain protein; Protein of unknown function UPF0004-like; SMART: Elongator protein 3/MiaB/NifB. (428 aa) |
| | Tpen_0614 | Hypothetical protein. (532 aa) |
| | rpl6 | LSU ribosomal protein L6P; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (191 aa) |
| | Tpen_0603 | PFAM: protein of unknown function UPF0047; KEGG: sso:SSO2532 hypothetical protein. (143 aa) |
| | Tpen_0586 | ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication. (396 aa) |
| | Tpen_0583 | PFAM: Shwachman-Bodian-Diamond syndrome proteins; KEGG: pai:PAE2209 hypothetical protein. (235 aa) |
| | Tpen_0570 | PFAM: histone deacetylase superfamily; KEGG: sto:ST2305 hypothetical acetoin utilization acuC protein. (360 aa) |
| | Tpen_0562 | PFAM: histidine triad (HIT) protein; KEGG: tko:TK0868 probable bis(5'-adenosyl)-triphosphatase, HIT family. (167 aa) |
| | nep1 | Suppressor Mra1; Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA. (232 aa) |
| | Tpen_0548 | KEGG: sai:Saci_1554 30S ribosomal protein S26E. (97 aa) |
| | rpl10e | PFAM: Ribosomal protein L10E; KEGG: pai:PAE3567 ribosomal protein L10; Belongs to the universal ribosomal protein uL16 family. (168 aa) |
| | albA-2 | Nucleoid protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family. (93 aa) |
| | Tpen_0530 | SMART: actin/actin family protein; KEGG: pai:PAE2276 hypothetical protein. (428 aa) |
| | Tpen_0529 | Hypothetical protein. (249 aa) |
| | Tpen_0527 | PFAM: SMC domain protein; KEGG: pai:PAE2280 hypothetical protein. (784 aa) |
| | Tpen_0526 | Hypothetical protein. (166 aa) |
| | rps15 | PFAM: ribosomal protein S15; Ribosomal S13S15-like; KEGG: mka:MK1593 ribosomal protein S15P/S13E. (148 aa) |
| | dnaG | TOPRIM domain protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. (426 aa) |
| | rpl24e | LSU ribosomal protein L24E; Binds to the 23S rRNA. (63 aa) |
| | hel308 | DEAD/DEAH box helicase domain protein; DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks. (739 aa) |
| | rps28e | PFAM: Ribosomal protein S28e; KEGG: sso:SSO5479 30S ribosomal protein S28e; Belongs to the eukaryotic ribosomal protein eS28 family. (77 aa) |
| | Tpen_0492 | PFAM: ribosomal RNA adenine methylase transferase; KEGG: pai:PAE3221 dimethyladenosine transferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (270 aa) |
| | rpl37ae | LSU ribosomal protein L37AE; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL43 family. Putative zinc-binding subfamily. (91 aa) |
| | rpl22 | LSU ribosomal protein L22P; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (127 aa) |
| | rps3 | SSU ribosomal protein S3P; Binds the lower part of the 30S subunit head. Belongs to the universal ribosomal protein uS3 family. (187 aa) |
| | rpl29 | PFAM: ribosomal protein L29; KEGG: sso:SSO6397 50S ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family. (84 aa) |
| | rps17 | SSU ribosomal protein S17P; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (111 aa) |
| | rpl14 | LSU ribosomal protein L14P; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (141 aa) |
| | Tpen_0478 | PFAM: DEAD_2 domain protein; SMART: DEXDc2; helicase c2; KEGG: pai:PAE2991 hypothetical protein. (588 aa) |
| | rpl31e | PFAM: Ribosomal protein L31e; KEGG: pai:PAE3095 ribosomal protein L31; Belongs to the ribosomal protein L31e family. (103 aa) |
| | rps19e | SSU ribosomal protein S19E; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (163 aa) |
| | rpl14e | KEGG: sto:STS054 50S ribosomal protein L14e; Belongs to the eukaryotic ribosomal protein eL14 family. (98 aa) |
| | truB | Putative rRNA pseudouridine synthase; Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 2 subfamily. (338 aa) |
| | Tpen_0458 | PFAM: metal-dependent phosphohydrolase, HD sub domain; SMART: metal-dependent phosphohydrolase, HD region; KEGG: sai:Saci_1517 hypothetical protein. (371 aa) |
| | Tpen_0454 | NMD3; PFAM: NMD3; KEGG: pai:PAE1653 hypothetical protein. (349 aa) |
| | rps24e | PFAM: Ribosomal protein S24e; KEGG: sso:SSO0435 30S ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. (106 aa) |
| | Tpen_0446 | PFAM: beta-lactamase domain protein; RNA-metabolising metallo-beta-lactamase; KEGG: pai:PAE3309 putative mRNA 3-end processing factor. (428 aa) |
| | Tpen_0444 | Conserved hypothetical protein; Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates. Belongs to the adenylate kinase family. AK6 subfamily. (183 aa) |
| | ftsY | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (302 aa) |
| | lig1 | DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. (531 aa) |
| | fen-2 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] (341 aa) |
| | rps6e | PFAM: ribosomal protein S6e; KEGG: mka:MK1446 ribosomal protein S6E (S10); Belongs to the eukaryotic ribosomal protein eS6 family. (131 aa) |
| | Tpen_0393 | KEGG: ape:APE2098 DNA-directed DNA polymerase; TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B. (794 aa) |
| | Tpen_0391 | TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; Nucleolar GTP-binding 1; KEGG: pai:PAE3626 hypothetical protein. (334 aa) |
| | Tpen_0390 | PFAM: Ribosomal protein L15e; KEGG: ape:APE1452 50S ribosomal protein L15e. (187 aa) |
| | flpA | rRNA 2'-O-methyltransferase fibrillarin; Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA; Belongs to the methyltransferase superfamily. Fibrillarin family. (233 aa) |
| | Tpen_0376 | rRNA biogenesis protein Nop56/Nop58; PFAM: Pre-mRNA processing ribonucleoprotein, binding region; NOSIC; KEGG: ape:APE2199 nucleolar protein NOP5. (412 aa) |
| | Tpen_0375 | KEGG: pfu:PF1791 gar1 - like small nucleolar rnp. (93 aa) |
| | rps8e | TIGRFAM: ribosomal protein S8e; PFAM: ribosomal protein S8E; KEGG: neq:NEQ469 SSU ribosomal protein S8E. (128 aa) |
| | tgtA | tRNA-guanine transglycosylases, various specificities; Exchanges the guanine residue with 7-cyano-7-deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D-loop) of archaeal tRNAs; Belongs to the archaeosine tRNA-ribosyltransferase family. (543 aa) |
| | rpl21e | PFAM: ribosomal protein L21e; KEGG: pai:PAE3334 ribosomal protein L21; Belongs to the eukaryotic ribosomal protein eL21 family. (102 aa) |
| | rps17e | PFAM: Ribosomal protein S17e; KEGG: pai:PAE0804 ribosomal protein S17; Belongs to the eukaryotic ribosomal protein eS17 family. (95 aa) |
| | Tpen_0348 | Archaeal histone; PFAM: Transcription factor CBF/NF-Y/archaeal histone; Histone core domain protein; KEGG: pho:PHS051 70aa long hypothetical archaeal histon. (86 aa) |
| | atpB | Sodium-transporting two-sector ATPase; Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit. (472 aa) |
| | Tpen_0331 | PFAM: helicase domain protein; DEAD/DEAH box helicase domain protein; SMART: DEAD-like helicases-like; KEGG: sto:ST0003 hypothetical protein. (1052 aa) |
| | rpl35ae | PFAM: Ribosomal protein L35Ae; KEGG: mka:MK0155 ribosomal protein L35AE/L33A; Belongs to the eukaryotic ribosomal protein eL33 family. (85 aa) |
| | Tpen_0319 | PFAM: peptidase M20; peptidase M28; KEGG: bld:BLi04074 YwaD. (416 aa) |
| | Tpen_0311 | PFAM: tRNA intron endonuclease, catalytic-like; tRNA intron endonuclease domain protein; KEGG: pab:PAB1099 tRNA intron endonuclease. (193 aa) |
| | Tpen_0310 | PFAM: PUA domain containing protein; KEGG: pai:PAE1626 PUA domain protein. (151 aa) |
| | fen | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] (346 aa) |
| | Tpen_0298 | PFAM: DNA polymerase B, exonuclease; DNA polymerase B region; SMART: DNA-directed DNA polymerase B; KEGG: pai:PAE2180 DNA-directed DNA polymerase (B1). (835 aa) |
| | rpl40e | PFAM: Ribosomal protein L40e; KEGG: pai:PAE3255 ribosomal protein L40; Belongs to the eukaryotic ribosomal protein eL40 family. (51 aa) |
| | Tpen_0293 | TATA binding protein of transcription factor TFIID; General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation. (142 aa) |
| | Tpen_0292 | Putative phage repressor; TIGRFAM: peptidase S26B, signal peptidase; PFAM: peptidase S24, S26A and S26B; KEGG: ape:APE1796 signal peptidase I. (129 aa) |
| | Tpen_0289 | KEGG: pai:PAE2275 hypothetical protein. (112 aa) |
| | rpl30e | PFAM: ribosomal protein L7Ae/L30e/S12e/Gadd45; KEGG: pab:PAB7152 50S ribosomal protein L30e; Belongs to the eukaryotic ribosomal protein eL30 family. (104 aa) |
| | rps12 | SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (147 aa) |
| | rpl18e | KEGG: tko:TK1502 LSU ribosomal protein L18E; Belongs to the eukaryotic ribosomal protein eL18 family. (120 aa) |
| | rps9 | PFAM: ribosomal protein S9; KEGG: afu:AF1129 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (132 aa) |
| | rps2 | PFAM: ribosomal protein S2; KEGG: pai:PAE0817 ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (214 aa) |
| | fni | Isopentenyl-diphosphate delta-isomerase, type 2; Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP). (361 aa) |
| | rps7 | SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (200 aa) |
| | rfcS | Replication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcS subfamily. (325 aa) |
| | rfcL | Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA; Belongs to the activator 1 small subunits family. RfcL subfamily. (413 aa) |
| | Tpen_0265 | ORC complex protein Cdc6/Orc1; Involved in regulation of DNA replication. (437 aa) |
| | rps13 | SSU ribosomal protein S13P; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (157 aa) |
| | rps4 | SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (172 aa) |
| | Tpen_0253 | PFAM: protein of unknown function, ATP binding; Miro domain protein; KEGG: ace:Acel_1323 small GTP-binding protein. (182 aa) |
| | rpl24 | LSU ribosomal protein L24P; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (131 aa) |
| | rps4e | PFAM: RNA-binding S4 domain protein; Ribosomal protein S4E-like; Ribosomal protein S4E, central; KEGG: ape:APE0356 30S ribosomal protein S4e; Belongs to the eukaryotic ribosomal protein eS4 family. (251 aa) |
| | rpl5 | LSU ribosomal protein L5P; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (182 aa) |
| | rps14 | SSU ribosomal protein S14P; Binds 16S rRNA, required for the assembly of 30S particles. (54 aa) |
| | rps8 | SSU ribosomal protein S8P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (129 aa) |
| | rpl32e | PFAM: Ribosomal protein L32e; KEGG: pai:PAE2099 ribosomal protein L32; Belongs to the eukaryotic ribosomal protein eL32 family. (159 aa) |
| | rpl19e | LSU ribosomal protein L19E; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (155 aa) |
| | rpl18 | LSU ribosomal protein L18P; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (196 aa) |
| | rps5 | SSU ribosomal protein S5P; With S4 and S12 plays an important role in translational accuracy. (202 aa) |
| | Tpen_0231 | PFAM: Protein of unknown function DUF171; KEGG: mtp:Mthe_1729 protein of unknown function DUF171. (273 aa) |
| | rpl3 | LSU ribosomal protein L3P; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (334 aa) |
| | rpl23 | LSU ribosomal protein L23P; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (90 aa) |
| | Tpen_0226 | PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: mtp:Mthe_1544 FAD-dependent pyridine nucleotide-disulphide oxidoreductase. (391 aa) |
| | rps19 | SSU ribosomal protein S19P; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (141 aa) |
| | rpl11 | LSU ribosomal protein L11P; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (168 aa) |
| | rpl1 | LSU ribosomal protein L1P; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (225 aa) |
| | rpl10 | LSU ribosomal protein L10P; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (294 aa) |
| | albA | Nucleoid protein Alba; Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes; Belongs to the histone-like Alba family. (91 aa) |
| | Tpen_0207 | Hydroxypyruvate reductase; PFAM: MOFRL domain protein; KEGG: sfu:Sfum_3915 MOFRL domain protein. (459 aa) |
| | Tpen_0206 | KEGG: tac:Ta1149 hypothetical protein. (142 aa) |
| | Tpen_0204 | PFAM: amine oxidase; FAD dependent oxidoreductase; KEGG: pho:PH0425 hypothetical protein. (435 aa) |
| | Tpen_0197 | TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: cation transporting ATPase domain protein domain protein; Haloacid dehalogenase domain protein hydrolase; cation transporting ATPase domain protein; E1-E2 ATPase-associated domain protein; KEGG: mac:MA4082 cation-transporting ATPase. (888 aa) |
| | Tpen_0195 | KEGG: mka:MK0077 predicted GTPase or GTP-binding protein. (421 aa) |
| | Tpen_0194 | PFAM: Appr-1-p processing domain protein; KEGG: sso:SSO2899 conserved hypothetical protein. (189 aa) |
| | Tpen_0164 | PFAM: ATPase associated with various cellular activities, AAA_3; ATPase associated with various cellular activities, AAA_5; KEGG: pho:PH0776 methanol dehydrogenase regulatory protein. (319 aa) |
| | Tpen_0161 | PFAM: Anion-transporting ATPase; KEGG: tvo:TVN0026 arsenite transporting ATPase. (300 aa) |
| | Tpen_0158 | PFAM: glycosyl transferase, family 2; KEGG: afu:AF1897 hypothetical protein. (386 aa) |
| | Tpen_0143 | NADPH:sulfur oxidoreductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; FAD dependent oxidoreductase; KEGG: afu:AF0395 NADH oxidase (NoxA-2). (452 aa) |
| | Tpen_0141 | PFAM: HhH-GPD family protein; SMART: iron-sulfur cluster loop; KEGG: sso:SSO0116 DNA endonuclease III, probable (ntH-1). (236 aa) |
| | Tpen_0114 | PFAM: monooxygenase, FAD-binding; FAD dependent oxidoreductase; KEGG: mta:Moth_0444 geranylgeranyl reductase. (399 aa) |
| | Tpen_0087 | PFAM: glycosyl transferase, family 2; KEGG: afu:AF1897 hypothetical protein. (374 aa) |
| | Tpen_0042 | PFAM: Dual specificity protein phosphatase; metal-dependent phosphohydrolase, HD sub domain; KEGG: tko:TK0241 protein-tyrosine phosphatase. (337 aa) |
| | Tpen_0038 | TIGRFAM: putative adenylyl cyclase CyaB; PFAM: adenylate cyclase; KEGG: pai:PAE0832 adenylate cyclase. (180 aa) |
| | Tpen_0021 | TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: mka:MK0970 predicted hydrolase of the HAD superfamily. (233 aa) |
| | Tpen_0017 | Deoxynucleoside 5'-monophosphate N-glycosidase; Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5-phosphate and a purine or pyrimidine base; Belongs to the 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 family. (143 aa) |
