STRINGSTRING
ABP52489.1 ABP52489.1 ABP52592.1 ABP52592.1 ABP52593.1 ABP52593.1 ABP52594.1 ABP52594.1 ABP52615.1 ABP52615.1 ABP52819.1 ABP52819.1 gpmA gpmA ABP52876.1 ABP52876.1 ABP53135.1 ABP53135.1 ABP53138.1 ABP53138.1 ABP53175.1 ABP53175.1 ABP53176.1 ABP53176.1 prs prs ABP53309.1 ABP53309.1 ABP53314.1 ABP53314.1 pckG pckG ABP53352.1 ABP53352.1 ppc ppc eno eno ABP53505.1 ABP53505.1 ABP53523.1 ABP53523.1 ABP53670.1 ABP53670.1 rbsK rbsK ABP53692.1 ABP53692.1 ABP53738.1 ABP53738.1 ABP53914.1 ABP53914.1 ABP54048.1 ABP54048.1 zwf zwf ABP54165.1 ABP54165.1 ABP54172.1 ABP54172.1 ABP54173.1 ABP54173.1 ABP54174.1 ABP54174.1 ABP54334.1 ABP54334.1 ABP54548.1 ABP54548.1 ABP54549.1 ABP54549.1 ABP54550.1 ABP54550.1 ABP54587.1 ABP54587.1 ABP54932.1 ABP54932.1 ABP54933.1 ABP54933.1 ABP55397.1 ABP55397.1 ABP55499.1 ABP55499.1 ABP55526.1 ABP55526.1 tal tal ABP55528.1 ABP55528.1 zwf-2 zwf-2 pgl pgl tpiA tpiA pgk pgk ABP55535.1 ABP55535.1 ABP55594.1 ABP55594.1 pfp pfp ABP55708.1 ABP55708.1 ABP55739.1 ABP55739.1 ABP55753.1 ABP55753.1 ABP55754.1 ABP55754.1 ABP55803.1 ABP55803.1 ABP55806.1 ABP55806.1 ABP55860.1 ABP55860.1 ABP55876.1 ABP55876.1 ABP55945.1 ABP55945.1 ABP56026.1 ABP56026.1 ABP56031.1 ABP56031.1 ABP56039.1 ABP56039.1 ABP56040.1 ABP56040.1 ABP56042.1 ABP56042.1 ABP56052.1 ABP56052.1 ABP56106.1 ABP56106.1 ABP56121.1 ABP56121.1 ABP56123.1 ABP56123.1 ackA ackA ABP56126.1 ABP56126.1 ABP56156.1 ABP56156.1 ABP56198.1 ABP56198.1 ABP56199.1 ABP56199.1 ABP56200.1 ABP56200.1 ABP56224.1 ABP56224.1 ABP56225.1 ABP56225.1 sucD sucD sucC sucC ABP56245.1 ABP56245.1 ABP56586.1 ABP56586.1 fumC fumC ABP56673.1 ABP56673.1 ABP56870.1 ABP56870.1 ABP56900.1 ABP56900.1 ABP56901.1 ABP56901.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABP52489.1TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase domain protein; 6-phosphogluconate dehydrogenase, NAD-binding. (290 aa)
ABP52592.1PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein. (487 aa)
ABP52593.1PFAM: Transketolase, central region; Transketolase domain protein. (329 aa)
ABP52594.1Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase, E1 component. (391 aa)
ABP52615.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (340 aa)
ABP52819.1PFAM: major facilitator superfamily MFS_1. (450 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (258 aa)
ABP52876.1PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein. (348 aa)
ABP53135.1Gluconolactonase; PFAM: SMP-30/Gluconolaconase/LRE domain protein. (307 aa)
ABP53138.1Glucose 1-dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KR. (259 aa)
ABP53175.1PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding. (344 aa)
ABP53176.1PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (630 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (326 aa)
ABP53309.1TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase. (547 aa)
ABP53314.1PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; HI0933 family protein; FAD dependent oxidoreductase. (467 aa)
pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (612 aa)
ABP53352.1TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein. (343 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (972 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
ABP53505.1PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase. (1149 aa)
ABP53523.1Hypothetical protein. (298 aa)
ABP53670.1PFAM: ROK family protein. (391 aa)
rbsKPfkB domain protein; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (298 aa)
ABP53692.1Transketolase domain protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (785 aa)
ABP53738.1PFAM: ROK family protein. (337 aa)
ABP53914.1Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: malic enzyme domain protein; malic enzyme, NAD-binding. (513 aa)
ABP54048.1Phosphoketolase; PFAM: D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase. (800 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (524 aa)
ABP54165.1TIGRFAM: phosphoglucomutase, alpha-D-glucose phosphate-specific; PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III. (549 aa)
ABP54172.1TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein. (251 aa)
ABP54173.1TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein. (643 aa)
ABP54174.1TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family. (227 aa)
ABP54334.1PFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (226 aa)
ABP54548.1Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase, E1 component. (382 aa)
ABP54549.1PFAM: Transketolase, central region; Transketolase domain protein. (334 aa)
ABP54550.1PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein. (433 aa)
ABP54587.1TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. (427 aa)
ABP54932.1Transketolase domain protein; PFAM: Transketolase, central region; Transketolase domain protein. (321 aa)
ABP54933.1PFAM: dehydrogenase, E1 component. (323 aa)
ABP55397.1PFAM: carbohydrate kinase, FGGY. (477 aa)
ABP55499.1Aconitase; TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein. (944 aa)
ABP55526.1TIGRFAM: transketolase; PFAM: Transketolase domain protein; Transketolase, central region; Belongs to the transketolase family. (741 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (392 aa)
ABP55528.1PFAM: phosphoglucose isomerase (PGI); Belongs to the GPI family. (555 aa)
zwf-2Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (505 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (256 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (263 aa)
pgkPFAM: phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (399 aa)
ABP55535.1TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
ABP55594.1PFAM: pyruvate kinase; Belongs to the pyruvate kinase family. (482 aa)
pfpPyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (342 aa)
ABP55708.1Glucokinase; TIGRFAM: putative glucokinase, ROK family; PFAM: ROK family protein. (315 aa)
ABP55739.1PFAM: glycerate kinase; Belongs to the glycerate kinase type-1 family. (378 aa)
ABP55753.1TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase. (481 aa)
ABP55754.12-oxoglutarate dehydrogenase E2 component; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein. (609 aa)
ABP55803.1PFAM: dehydrogenase, E1 component; Transketolase, central region; Transketolase domain protein. (792 aa)
ABP55806.12-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (912 aa)
ABP55860.1TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing enzyme; pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region; Belongs to the PEP-utilizing enzyme family. (911 aa)
ABP55876.16-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (478 aa)
ABP55945.1Ribose 5-phosphate isomerase; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase; PFAM: Ribose/galactose isomerase. (155 aa)
ABP56026.1Hypothetical protein. (379 aa)
ABP56031.1Hypothetical protein. (207 aa)
ABP56039.1TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase. (562 aa)
ABP56040.1TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; SMART: AAA ATPase. (345 aa)
ABP56042.1methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase. (157 aa)
ABP56052.1TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. (668 aa)
ABP56106.1PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region. (456 aa)
ABP56121.1TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase, E1 component; catalytic domain of components of various dehydrogenase complexes; Transketolase, central region. (1270 aa)
ABP56123.1Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (691 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (371 aa)
ABP56126.1Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: malic enzyme domain protein; malic enzyme, NAD-binding. (391 aa)
ABP56156.1TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase. (312 aa)
ABP56198.1Hypothetical protein. (272 aa)
ABP56199.1PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase. (637 aa)
ABP56200.1TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin. (366 aa)
ABP56224.1TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (404 aa)
ABP56225.1Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. (316 aa)
sucDsuccinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa)
sucCsuccinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (392 aa)
ABP56245.1PFAM: cobalamin B12-binding domain protein. (134 aa)
ABP56586.1PFAM: fructose-bisphosphate aldolase, class-I. (295 aa)
fumCFumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (466 aa)
ABP56673.1Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (568 aa)
ABP56870.1PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region. (469 aa)
ABP56900.1PFAM: Transketolase domain protein. (242 aa)
ABP56901.1PFAM: Transketolase, central region. (296 aa)
Your Current Organism:
Salinispora tropica
NCBI taxonomy Id: 369723
Other names: S. tropica CNB-440, Salinispora sp. CNB-440, Salinispora tropica ATCC BAA-916, Salinispora tropica CNB-440, Salinispora tropica str. CNB-440, Salinispora tropica strain CNB-440
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