STRINGSTRING
rex rex hemA hemA hemC hemC ABP52843.1 ABP52843.1 ABP52844.1 ABP52844.1 hemE hemE ABP53999.1 ABP53999.1 ABP54637.1 ABP54637.1 ABP54962.1 ABP54962.1 ABP54963.1 ABP54963.1 ABP54964.1 ABP54964.1 ABP54965.1 ABP54965.1 ABP54966.1 ABP54966.1 cbiD cbiD ABP54968.1 ABP54968.1 ABP54969.1 ABP54969.1 cobB-2 cobB-2 ABP54971.1 ABP54971.1 ABP54972.1 ABP54972.1 ABP54973.1 ABP54973.1 hemH hemH ABP55747.1 ABP55747.1 cobS cobS ABP55976.1 ABP55976.1 cobT cobT cobQ cobQ cobD cobD ABP56057.1 ABP56057.1 ABP56525.1 ABP56525.1 ABP56526.1 ABP56526.1 ABP56527.1 ABP56527.1 ABP56528.1 ABP56528.1 ABP56529.1 ABP56529.1 hemL hemL ABP56749.1 ABP56749.1 ABP56876.1 ABP56876.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rexCoA-binding domain protein; Modulates transcription in response to changes in cellular NADH/NAD(+) redox state. (256 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (455 aa)
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (322 aa)
ABP52843.1uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4. (526 aa)
ABP52844.1Porphobilinogen synthase; PFAM: delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (327 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (371 aa)
ABP53999.1Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (469 aa)
ABP54637.1Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (488 aa)
ABP54962.1TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiX protein. (553 aa)
ABP54963.1PFAM: Precorrin-8X methylmutase CbiC/CobH. (196 aa)
ABP54964.1PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein. (85 aa)
ABP54965.1TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein. (577 aa)
ABP54966.1TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. (425 aa)
cbiDCobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (380 aa)
ABP54968.1TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. (298 aa)
ABP54969.1TIGRFAM: precorrin-2 C20-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family. (247 aa)
cobB-2Hydrogenobyrinate a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (452 aa)
ABP54971.1cob(I)yrinic acid a,c-diamide adenosyltransferase; TIGRFAM: cob(I)alamin adenosyltransferase; PFAM: ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. (203 aa)
ABP54972.1Protoporphyrin IX magnesium-chelatase; PFAM: von Willebrand factor, type A; ATPase associated with various cellular activities, AAA_5; SMART: AAA ATPase. (738 aa)
ABP54973.1Hydrogenobyrinic acid a,c-diamide cobaltochelatase; TIGRFAM: cobaltochelatase, CobN subunit; PFAM: CobN/magnesium chelatase. (1222 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (360 aa)
ABP55747.1Cobalbumin biosynthesis protein; PFAM: Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; cobalbumin biosynthesis enzyme. (627 aa)
cobSCobalamin-5'-phosphate synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (257 aa)
ABP55976.1TIGRFAM: uroporphyrin-III C-methyltransferase; siroheme synthase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase. (417 aa)
cobTNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (364 aa)
cobQAdenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (521 aa)
cobDAdenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (333 aa)
ABP56057.1TIGRFAM: ATP--cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (190 aa)
ABP56525.1PFAM: cytochrome c assembly protein. (325 aa)
ABP56526.1PFAM: ResB family protein. (545 aa)
ABP56527.1PFAM: cytochrome c biogenesis protein, transmembrane region. (285 aa)
ABP56528.1PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein. (191 aa)
ABP56529.1PFAM: Phosphoglycerate mutase. (217 aa)
hemLTIGRFAM: glutamate-1-semialdehyde-2,1-aminomutase; PFAM: aminotransferase, class I and II; aminotransferase class-III. (448 aa)
ABP56749.1PFAM: protein of unknown function DUF105. (228 aa)
ABP56876.1TIGRFAM: cob(II)yrinic acid a,c-diamide reductase; PFAM: nitroreductase. (209 aa)
Your Current Organism:
Salinispora tropica
NCBI taxonomy Id: 369723
Other names: S. tropica CNB-440, Salinispora sp. CNB-440, Salinispora tropica ATCC BAA-916, Salinispora tropica CNB-440, Salinispora tropica str. CNB-440, Salinispora tropica strain CNB-440
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