STRINGSTRING
ABP52592.1 ABP52592.1 ABP52593.1 ABP52593.1 ABP52594.1 ABP52594.1 ABP52908.1 ABP52908.1 ABP53175.1 ABP53175.1 ABP53176.1 ABP53176.1 pckG pckG ABP53692.1 ABP53692.1 ABP54172.1 ABP54172.1 ABP54173.1 ABP54173.1 ABP54174.1 ABP54174.1 ABP54548.1 ABP54548.1 ABP54549.1 ABP54549.1 ABP54550.1 ABP54550.1 ABP54587.1 ABP54587.1 ABP55499.1 ABP55499.1 ABP55753.1 ABP55753.1 ABP55754.1 ABP55754.1 ABP55806.1 ABP55806.1 ABP56121.1 ABP56121.1 ABP56199.1 ABP56199.1 ABP56200.1 ABP56200.1 ABP56224.1 ABP56224.1 ABP56225.1 ABP56225.1 sucD sucD sucC sucC fumC fumC ABP56673.1 ABP56673.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ABP52592.1PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein. (487 aa)
ABP52593.1PFAM: Transketolase, central region; Transketolase domain protein. (329 aa)
ABP52594.1Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase, E1 component. (391 aa)
ABP52908.1PFAM: Citrate synthase; Belongs to the citrate synthase family. (368 aa)
ABP53175.1PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding. (344 aa)
ABP53176.1PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (630 aa)
pckGPhosphoenolpyruvate carboxykinase (GTP); Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. (612 aa)
ABP53692.1Transketolase domain protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (785 aa)
ABP54172.1TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein. (251 aa)
ABP54173.1TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein. (643 aa)
ABP54174.1TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family. (227 aa)
ABP54548.1Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase, E1 component. (382 aa)
ABP54549.1PFAM: Transketolase, central region; Transketolase domain protein. (334 aa)
ABP54550.1PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein. (433 aa)
ABP54587.1TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. (427 aa)
ABP55499.1Aconitase; TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein. (944 aa)
ABP55753.1TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase. (481 aa)
ABP55754.12-oxoglutarate dehydrogenase E2 component; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein. (609 aa)
ABP55806.12-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (912 aa)
ABP56121.1TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase, E1 component; catalytic domain of components of various dehydrogenase complexes; Transketolase, central region. (1270 aa)
ABP56199.1PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase. (637 aa)
ABP56200.1TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin. (366 aa)
ABP56224.1TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (404 aa)
ABP56225.1Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. (316 aa)
sucDsuccinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa)
sucCsuccinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (392 aa)
fumCFumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (466 aa)
ABP56673.1Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (568 aa)
Your Current Organism:
Salinispora tropica
NCBI taxonomy Id: 369723
Other names: S. tropica CNB-440, Salinispora sp. CNB-440, Salinispora tropica ATCC BAA-916, Salinispora tropica CNB-440, Salinispora tropica str. CNB-440, Salinispora tropica strain CNB-440
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