STRINGSTRING
ABP52489.1 ABP52489.1 ABP52510.1 ABP52510.1 ABP52592.1 ABP52592.1 ABP52593.1 ABP52593.1 ABP52594.1 ABP52594.1 ABP52615.1 ABP52615.1 ABP52627.1 ABP52627.1 ABP52648.1 ABP52648.1 ABP52731.1 ABP52731.1 gpmA gpmA ABP52907.1 ABP52907.1 ABP52908.1 ABP52908.1 ABP52915.1 ABP52915.1 ABP53135.1 ABP53135.1 ABP53138.1 ABP53138.1 ABP53175.1 ABP53175.1 ABP53176.1 ABP53176.1 prs prs ABP53309.1 ABP53309.1 ABP53326.1 ABP53326.1 ABP53333.1 ABP53333.1 ABP53352.1 ABP53352.1 ppc ppc eno eno ABP53385.1 ABP53385.1 ABP53399.1 ABP53399.1 ABP53439.1 ABP53439.1 ABP53492.1 ABP53492.1 ABP53692.1 ABP53692.1 ABP53706.1 ABP53706.1 ABP53738.1 ABP53738.1 ABP53914.1 ABP53914.1 zwf zwf ABP54172.1 ABP54172.1 ABP54173.1 ABP54173.1 ABP54174.1 ABP54174.1 ABP54334.1 ABP54334.1 glyA glyA ABP54548.1 ABP54548.1 ABP54549.1 ABP54549.1 ABP54550.1 ABP54550.1 ABP54587.1 ABP54587.1 folD1 folD1 gcvP gcvP gcvH gcvH ABP54949.1 ABP54949.1 ABP54950.1 ABP54950.1 ABP55044.1 ABP55044.1 ABP55052.1 ABP55052.1 ABP55057.1 ABP55057.1 ABP55088.1 ABP55088.1 ABP55242.1 ABP55242.1 ABP55397.1 ABP55397.1 ABP55430.1 ABP55430.1 ABP55499.1 ABP55499.1 ABP55526.1 ABP55526.1 tal tal ABP55528.1 ABP55528.1 zwf-2 zwf-2 pgl pgl tpiA tpiA pgk pgk ABP55535.1 ABP55535.1 ABP55594.1 ABP55594.1 ABP55684.1 ABP55684.1 pfp pfp ABP55708.1 ABP55708.1 ABP55750.1 ABP55750.1 ABP55753.1 ABP55753.1 ABP55754.1 ABP55754.1 ABP55806.1 ABP55806.1 ABP55815.1 ABP55815.1 ABP55860.1 ABP55860.1 ABP55876.1 ABP55876.1 ABP55945.1 ABP55945.1 ABP56026.1 ABP56026.1 ABP56039.1 ABP56039.1 ABP56041.1 ABP56041.1 ABP56042.1 ABP56042.1 ABP56043.1 ABP56043.1 ABP56049.1 ABP56049.1 ABP56052.1 ABP56052.1 ABP56055.1 ABP56055.1 ABP56121.1 ABP56121.1 ABP56123.1 ABP56123.1 ackA ackA ABP56126.1 ABP56126.1 ABP56156.1 ABP56156.1 ABP56199.1 ABP56199.1 ABP56200.1 ABP56200.1 ABP56224.1 ABP56224.1 ABP56225.1 ABP56225.1 folD2 folD2 sucD sucD sucC sucC ABP56245.1 ABP56245.1 acsA acsA ABP56519.1 ABP56519.1 ABP56586.1 ABP56586.1 fumC fumC ABP56673.1 ABP56673.1 ABP56756.1 ABP56756.1 ABP56761.1 ABP56761.1 ABP56900.1 ABP56900.1 ABP56901.1 ABP56901.1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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protein homology
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ABP52489.1TIGRFAM: 6-phosphogluconate dehydrogenase, decarboxylating; PFAM: 6-phosphogluconate dehydrogenase domain protein; 6-phosphogluconate dehydrogenase, NAD-binding. (290 aa)
ABP52510.1PFAM: phosphoribosylglycinamide synthetase; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein. (445 aa)
ABP52592.1PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein. (487 aa)
ABP52593.1PFAM: Transketolase, central region; Transketolase domain protein. (329 aa)
ABP52594.1Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase, E1 component. (391 aa)
ABP52615.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (340 aa)
ABP52627.13-ketoacyl-CoA thiolase; TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (430 aa)
ABP52648.1PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding. (285 aa)
ABP52731.1PFAM: ROK family protein. (321 aa)
gpmAPhosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (258 aa)
ABP52907.1Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (417 aa)
ABP52908.1PFAM: Citrate synthase; Belongs to the citrate synthase family. (368 aa)
ABP52915.12-hydroxymethylglutarate dehydratase / L-serine ammonia-lyase; TIGRFAM: L-serine dehydratase 1; PFAM: serine dehydratase alpha chain; serine dehydratase beta chain; Belongs to the iron-sulfur dependent L-serine dehydratase family. (465 aa)
ABP53135.1Gluconolactonase; PFAM: SMP-30/Gluconolaconase/LRE domain protein. (307 aa)
ABP53138.1Glucose 1-dehydrogenase; PFAM: short-chain dehydrogenase/reductase SDR; KR. (259 aa)
ABP53175.1PFAM: thiamine pyrophosphate enzyme domain protein TPP-binding. (344 aa)
ABP53176.1PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein. (630 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (326 aa)
ABP53309.1TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase. (547 aa)
ABP53326.1Carbamoyl-phosphate synthase L chain, ATP-binding; PFAM: biotin/lipoyl attachment domain-containing protein; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein. (583 aa)
ABP53333.1PFAM: carboxyl transferase. (527 aa)
ABP53352.1TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein. (343 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (972 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
ABP53385.1TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (420 aa)
ABP53399.1L-threonine ammonia-lyase; TIGRFAM: threonine dehydratase; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; amino acid-binding ACT domain protein. (403 aa)
ABP53439.1Hypothetical protein. (398 aa)
ABP53492.1TIGRFAM: crotonyl-CoA reductase; PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein. (460 aa)
ABP53692.1Transketolase domain protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (785 aa)
ABP53706.1TIGRFAM: D-3-phosphoglycerate dehydrogenase; PFAM: amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (531 aa)
ABP53738.1PFAM: ROK family protein. (337 aa)
ABP53914.1Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: malic enzyme domain protein; malic enzyme, NAD-binding. (513 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (524 aa)
ABP54172.1TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein. (251 aa)
ABP54173.1TIGRFAM: succinate dehydrogenase or fumarate reductase, flavoprotein subunit; PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein. (643 aa)
ABP54174.1TIGRFAM: succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family. (227 aa)
ABP54334.1PFAM: ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (226 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (478 aa)
ABP54548.1Pyruvate dehydrogenase (acetyl-transferring); PFAM: dehydrogenase, E1 component. (382 aa)
ABP54549.1PFAM: Transketolase, central region; Transketolase domain protein. (334 aa)
ABP54550.1PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein. (433 aa)
ABP54587.1TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. (427 aa)
folD1Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (306 aa)
gcvPGlycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (938 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)
ABP54949.1Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha / biotin carboxylase; PFAM: phosphoribosylglycinamide synthetase; ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein. (458 aa)
ABP54950.1acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (192 aa)
ABP55044.1PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein. (363 aa)
ABP55052.1TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (377 aa)
ABP55057.1TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (387 aa)
ABP55088.1Propanoyl-CoA C-acyltransferase. (391 aa)
ABP55242.1TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (383 aa)
ABP55397.1PFAM: carbohydrate kinase, FGGY. (477 aa)
ABP55430.1TIGRFAM: methylmalonate-semialdehyde dehydrogenase; PFAM: aldehyde dehydrogenase. (496 aa)
ABP55499.1Aconitase; TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein. (944 aa)
ABP55526.1TIGRFAM: transketolase; PFAM: Transketolase domain protein; Transketolase, central region; Belongs to the transketolase family. (741 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (392 aa)
ABP55528.1PFAM: phosphoglucose isomerase (PGI); Belongs to the GPI family. (555 aa)
zwf-2Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (505 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (256 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (263 aa)
pgkPFAM: phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (399 aa)
ABP55535.1TIGRFAM: glyceraldehyde-3-phosphate dehydrogenase, type I; PFAM: glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (334 aa)
ABP55594.1PFAM: pyruvate kinase; Belongs to the pyruvate kinase family. (482 aa)
ABP55684.1TIGRFAM: 5,10-methylenetetrahydrofolate reductase; PFAM: methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (305 aa)
pfpPyrophosphate-dependent phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (342 aa)
ABP55708.1Glucokinase; TIGRFAM: putative glucokinase, ROK family; PFAM: ROK family protein. (315 aa)
ABP55750.1TIGRFAM: glycine cleavage system T protein; PFAM: glycine cleavage T protein (aminomethyl transferase); Glycine cleavage T-protein, C-terminal barrel. (387 aa)
ABP55753.1TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; glucose-inhibited division protein A; pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD dependent oxidoreductase. (481 aa)
ABP55754.12-oxoglutarate dehydrogenase E2 component; PFAM: biotin/lipoyl attachment domain-containing protein; catalytic domain of components of various dehydrogenase complexes; E3 binding domain protein. (609 aa)
ABP55806.12-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (912 aa)
ABP55815.1Propionyl-CoA carboxylase; PFAM: carboxyl transferase. (474 aa)
ABP55860.1TIGRFAM: pyruvate, phosphate dikinase; PFAM: PEP-utilizing enzyme; pyruvate phosphate dikinase, PEP/pyruvate-binding; PEP-utilising enzyme, mobile region; Belongs to the PEP-utilizing enzyme family. (911 aa)
ABP55876.16-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (478 aa)
ABP55945.1Ribose 5-phosphate isomerase; TIGRFAM: sugar-phosphate isomerase, RpiB/LacA/LacB family; ribose 5-phosphate isomerase; PFAM: Ribose/galactose isomerase. (155 aa)
ABP56026.1Hypothetical protein. (379 aa)
ABP56039.1TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase. (562 aa)
ABP56041.1TIGRFAM: acetyl-CoA acetyltransferase; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (399 aa)
ABP56042.1methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase. (157 aa)
ABP56043.1TIGRFAM: crotonyl-CoA reductase; PFAM: Alcohol dehydrogenase, zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein. (468 aa)
ABP56049.1PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding. (596 aa)
ABP56052.1TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein. (668 aa)
ABP56055.1PFAM: 3-hydroxyacyl-CoA dehydrogenase domain protein; 3-hydroxyacyl-CoA dehydrogenase, NAD-binding. (283 aa)
ABP56121.1TIGRFAM: 2-oxoglutarate dehydrogenase, E1 subunit; PFAM: dehydrogenase, E1 component; catalytic domain of components of various dehydrogenase complexes; Transketolase, central region. (1270 aa)
ABP56123.1Phosphotransacetylase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (691 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (371 aa)
ABP56126.1Malate dehydrogenase (oxaloacetate-decarboxylating); PFAM: malic enzyme domain protein; malic enzyme, NAD-binding. (391 aa)
ABP56156.1TIGRFAM: ribose-phosphate pyrophosphokinase; PFAM: phosphoribosyltransferase. (312 aa)
ABP56199.1PFAM: fumarate reductase/succinate dehydrogenase flavoprotein domain protein; FAD dependent oxidoreductase. (637 aa)
ABP56200.1TIGRFAM: succinate dehydrogenase and fumarate reductase iron-sulfur protein; PFAM: ferredoxin. (366 aa)
ABP56224.1TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: isocitrate/isopropylmalate dehydrogenase; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (404 aa)
ABP56225.1Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. (316 aa)
folD2Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (286 aa)
sucDsuccinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa)
sucCsuccinyl-CoA synthetase (ADP-forming) beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (392 aa)
ABP56245.1PFAM: cobalamin B12-binding domain protein. (134 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (715 aa)
ABP56519.1PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (363 aa)
ABP56586.1PFAM: fructose-bisphosphate aldolase, class-I. (295 aa)
fumCFumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (466 aa)
ABP56673.1Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (568 aa)
ABP56756.1Carbamoyl-phosphate synthase L chain, ATP-binding; PFAM: biotin/lipoyl attachment domain-containing protein; protein of unknown function DUF201; Carbamoyl-phosphate synthase L chain, ATP-binding; Carbamoyl-phosphate synthetase large chain domain protein; biotin carboxylase domain protein; D-alanine--D-alanine ligase domain protein. (674 aa)
ABP56761.1PFAM: ROK family protein. (326 aa)
ABP56900.1PFAM: Transketolase domain protein. (242 aa)
ABP56901.1PFAM: Transketolase, central region. (296 aa)
Your Current Organism:
Salinispora tropica
NCBI taxonomy Id: 369723
Other names: S. tropica CNB-440, Salinispora sp. CNB-440, Salinispora tropica ATCC BAA-916, Salinispora tropica CNB-440, Salinispora tropica str. CNB-440, Salinispora tropica strain CNB-440
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