(99 nodes) Mixed, incl. Myogenesis, and RUNX1 regulates transcription of genes involved in differentiation of HSCs network (Kryptolebias marmoratus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pax5	Paired box 5. (386 aa)
	tbx20	T-box transcription factor 20. (439 aa)
	msx1	Muscle segment homeobox 1a. (289 aa)
	id4	Inhibitor of DNA binding 4. (153 aa)
	ENSKMAP00000001177	Zinc finger protein, FOG family member 1. (843 aa)
	HCN4	Hyperpolarization activated cyclic nucleotide gated potassium channel 4. (1159 aa)
	LOC108230716	LIM homeobox transcription factor 1, alpha. (363 aa)
	ENSKMAP00000002023	MADS-box domain-containing protein. (80 aa)
	lmo2	LIM domain only 2 (rhombotin-like 1). (160 aa)
	LOC108229875	ALX homeobox 4b. (367 aa)
	LOC108236478	LIM homeobox transcription factor 1, beta b. (383 aa)
	zic3	Zic family member 3 heterotaxy 1 (odd-paired homolog, Drosophila). (490 aa)
	LOC108239928	Achaete-scute family bHLH transcription factor 1b. (191 aa)
	zfpm2	Zinc finger protein, FOG family member 2a. (1170 aa)
	ets1	V-ets avian erythroblastosis virus E26 oncogene homolog 1. (488 aa)
	fli1	Fli-1 proto-oncogene, ETS transcription factor a. (458 aa)
	LOC108230815	Single stranded DNA binding protein 3b. (390 aa)
	LOC108229813	Spi-1 proto-oncogene b. (300 aa)
	LOC108231893	T-box transcription factor 18. (523 aa)
	LOC108230802	Single stranded DNA binding protein 4. (385 aa)
	mymk	Myomaker, myoblast fusion factor. (223 aa)
	LOC108230787	Transcription factor 3b. (630 aa)
	HAND1	Heart and neural crest derivatives expressed 1. (166 aa)
	gata6	GATA binding protein 6. (495 aa)
	celf5	Cugbp, Elav-like family member 5a. (522 aa)
	lmo1	LIM domain only 1. (155 aa)
	LOC108228750	Uncharacterized protein. (332 aa)
	ENSKMAP00000006157	Uncharacterized protein. (391 aa)
	nkx6-3	NK6 homeobox 3. (271 aa)
	lcp1	Lymphocyte cytosolic protein 1 (L-plastin). (619 aa)
	Mef2b	MADS-box domain-containing protein. (90 aa)
	gsx2	GS homeobox 2. (237 aa)
	DMRTA1	DMRT like family A1. (411 aa)
	LOC108239464	Transcription factor 3a. (646 aa)
	LOC108241221	GATA binding protein 2a. (458 aa)
	Tcf4	Uncharacterized protein. (199 aa)
	ENSKMAP00000009381	Uncharacterized protein. (78 aa)
	ENSKMAP00000009463	BHLH domain-containing protein. (116 aa)
	ENSKMAP00000009532	LIM zinc-binding domain-containing protein. (84 aa)
	msc	Musculin (activated B-cell factor-1). (165 aa)
	id2	Inhibitor of DNA binding 2a. (139 aa)
	ENSKMAP00000010393	Runt domain-containing protein. (172 aa)
	ENSKMAP00000010642	BHLH domain-containing protein. (130 aa)
	TCF24	Transcription factor 24. (144 aa)
	tcf12	Transcription factor 12. (717 aa)
	ENSKMAP00000010949	Homeobox domain-containing protein. (156 aa)
	ENSKMAP00000011069	RUNX family transcription factor 1. (198 aa)
	btg1	B-cell translocation gene 1, anti-proliferative. (178 aa)
	nkx2-5	NK2 homeobox 5. (302 aa)
	LOC108236683	LIM domain binding 2a. (388 aa)
	LOC108243494	Short stature homeobox 2. (263 aa)
	LOC108249851	Fli-1 proto-oncogene, ETS transcription factor b. (490 aa)
	LOC108249856	Ets variant 2. (322 aa)
	LOC108233854	LIM homeobox 1b. (426 aa)
	LOC108239578	T-cell acute lymphocytic leukemia 1. (385 aa)
	MEF2D	Myocyte enhancer factor 2D. (579 aa)
	LOC108248187	Uncharacterized protein. (155 aa)
	LOC108246420	Si:dkey-90l8.3. (159 aa)
	lmo3	LIM domain only 3. (156 aa)
	myb	V-myb avian myeloblastosis viral oncogene homolog. (606 aa)
	myf5	Myogenic factor. (240 aa)
	myf6	Myogenic factor 6. (238 aa)
	tcf21	Transcription factor 21. (179 aa)
	LOC108249382	RUNX family transcription factor 1. (257 aa)
	LOC108246457	LIM homeobox transcription factor 1, beta a. (367 aa)
	LOC108235069	LisH domain-containing protein. (383 aa)
	cbfb	Core-binding factor subunit beta. (188 aa)
	slc25a21	Solute carrier family 25 member 21; Belongs to the mitochondrial carrier (TC 2.A.29) family. (294 aa)
	MYOD1	Myogenic factor. (267 aa)
	runx3	Runt-related transcription factor. (421 aa)
	lmcd1	LIM and cysteine-rich domains 1. (348 aa)
	LOC108246522	Transcription factor 23. (148 aa)
	myog	Myogenin. (250 aa)
	LOC108241354	LIM homeobox transcription factor 1, alpha-like. (410 aa)
	mef2a	Myocyte enhancer factor 2aa. (515 aa)
	LHX3	LIM homeobox 3. (400 aa)
	LOC108239741	Homeobox protein HOXD12a. (254 aa)
	hand2	Heart and neural crest derivatives expressed 2. (245 aa)
	LOC108238512	Homeobox domain-containing protein. (315 aa)
	LOC108243234	Myocyte enhancer factor 2d. (595 aa)
	LOC108229936	ISL LIM homeobox 2a. (360 aa)
	gata5	GATA binding protein 5. (318 aa)
	LOC108230888	T-box transcription factor 5a. (519 aa)
	tbx3	T-box transcription factor 3a. (711 aa)
	LOC108242789	Paired box 2a. (417 aa)
	ISL2	ISL LIM homeobox 2b. (364 aa)
	isl1	ISL LIM homeobox 1. (349 aa)
	LOC108246136	Si:dkey-43p13.5. (192 aa)
	LOC108244322	BHLH domain-containing protein. (445 aa)
	LOC108236378	LIM-domain binding 1b. (414 aa)
	GATA2	Uncharacterized protein. (467 aa)
	dbx1	Developing brain homeobox 1a. (320 aa)
	LOC108234073	LIM domain binding 1a. (405 aa)
	LOC108244378	GATA binding protein 1a. (426 aa)
	nav3	Neuron navigator 3. (2332 aa)
	LOC108242136	Myogenic factor. (268 aa)
	LOC108244375	Inhibitor of DNA binding 1, HLH protein. (129 aa)
	LOC108229889	BHLH domain-containing protein. (494 aa)
	lhx4	LIM homeobox 4. (389 aa)

Your Current Organism:

Kryptolebias marmoratus

NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DMRTA1	LOC108230716	ENSKMAP00000008438	ENSKMAP00000001332	DMRT like family A1.	LIM homeobox transcription factor 1, alpha.	0.547
DMRTA1	gsx2	ENSKMAP00000008438	ENSKMAP00000007860	DMRT like family A1.	GS homeobox 2.	0.637
ENSKMAP00000001177	ENSKMAP00000009463	ENSKMAP00000001177	ENSKMAP00000009463	Zinc finger protein, FOG family member 1.	BHLH domain-containing protein.	0.429
ENSKMAP00000001177	ENSKMAP00000011069	ENSKMAP00000001177	ENSKMAP00000011069	Zinc finger protein, FOG family member 1.	RUNX family transcription factor 1.	0.424
ENSKMAP00000001177	GATA2	ENSKMAP00000001177	ENSKMAP00000026926	Zinc finger protein, FOG family member 1.	Uncharacterized protein.	0.647
ENSKMAP00000001177	LOC108228750	ENSKMAP00000001177	ENSKMAP00000005867	Zinc finger protein, FOG family member 1.	Uncharacterized protein.	0.891
ENSKMAP00000001177	LOC108239578	ENSKMAP00000001177	ENSKMAP00000013785	Zinc finger protein, FOG family member 1.	T-cell acute lymphocytic leukemia 1.	0.429
ENSKMAP00000001177	LOC108241221	ENSKMAP00000001177	ENSKMAP00000009161	Zinc finger protein, FOG family member 1.	GATA binding protein 2a.	0.647
ENSKMAP00000001177	LOC108244378	ENSKMAP00000001177	ENSKMAP00000028401	Zinc finger protein, FOG family member 1.	GATA binding protein 1a.	0.891
ENSKMAP00000001177	LOC108249382	ENSKMAP00000001177	ENSKMAP00000016511	Zinc finger protein, FOG family member 1.	RUNX family transcription factor 1.	0.485
ENSKMAP00000001177	cbfb	ENSKMAP00000001177	ENSKMAP00000017594	Zinc finger protein, FOG family member 1.	Core-binding factor subunit beta.	0.530
ENSKMAP00000001177	gata5	ENSKMAP00000001177	ENSKMAP00000023342	Zinc finger protein, FOG family member 1.	GATA binding protein 5.	0.682
ENSKMAP00000001177	gata6	ENSKMAP00000001177	ENSKMAP00000004464	Zinc finger protein, FOG family member 1.	GATA binding protein 6.	0.682
ENSKMAP00000001177	lmo2	ENSKMAP00000001177	ENSKMAP00000002065	Zinc finger protein, FOG family member 1.	LIM domain only 2 (rhombotin-like 1).	0.667
ENSKMAP00000001177	runx3	ENSKMAP00000001177	ENSKMAP00000018620	Zinc finger protein, FOG family member 1.	Runt-related transcription factor.	0.424
ENSKMAP00000002023	LOC108242136	ENSKMAP00000002023	ENSKMAP00000028640	MADS-box domain-containing protein.	Myogenic factor.	0.482
ENSKMAP00000002023	LOC108243234	ENSKMAP00000002023	ENSKMAP00000022797	MADS-box domain-containing protein.	Myocyte enhancer factor 2d.	0.554
ENSKMAP00000002023	MEF2D	ENSKMAP00000002023	ENSKMAP00000014002	MADS-box domain-containing protein.	Myocyte enhancer factor 2D.	0.555
ENSKMAP00000002023	MYOD1	ENSKMAP00000002023	ENSKMAP00000018491	MADS-box domain-containing protein.	Myogenic factor.	0.482
ENSKMAP00000002023	Mef2b	ENSKMAP00000002023	ENSKMAP00000007002	MADS-box domain-containing protein.	MADS-box domain-containing protein.	0.628