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| | rfc1 | Replication factor C subunit 1. (1180 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa) |
| | ENSKMAP00000000467 | TAN domain-containing protein. (123 aa) |
| | Atm | Uncharacterized protein. (130 aa) |
| | ENSKMAP00000001053 | Uncharacterized protein. (109 aa) |
| | rev1 | REV1 DNA directed polymerase. (1363 aa) |
| | rfc5 | Replication factor C (activator 1) 5. (339 aa) |
| | xrcc3 | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (343 aa) |
| | CDCA7L | zf-4CXXC_R1 domain-containing protein. (406 aa) |
| | top3b | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (858 aa) |
| | cdc7 | Cell division cycle 7 homolog (S. cerevisiae). (547 aa) |
| | msh3 | MutS homolog 3 (E. coli); Component of the post-replicative DNA mismatch repair system (MMR). (972 aa) |
| | mus81 | MUS81 structure-specific endonuclease subunit. (556 aa) |
| | gins1 | GINS complex subunit 1 (Psf1 homolog). (196 aa) |
| | xpc | Xeroderma pigmentosum, complementation group C. (935 aa) |
| | mlh3 | MutL homolog 3 (E. coli). (1121 aa) |
| | pold2 | Polymerase (DNA directed), delta 2, regulatory subunit. (471 aa) |
| | pcna | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa) |
| | brip1 | BRCA1 interacting protein C-terminal helicase 1. (1177 aa) |
| | LOC108244487 | Zgc:110269. (346 aa) |
| | cdc45 | CDC45 cell division cycle 45 homolog (S. cerevisiae). (572 aa) |
| | nbn | Nibrin. (832 aa) |
| | chtf8 | CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae). (136 aa) |
| | cdc6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (575 aa) |
| | dbf4 | DBF4 zinc finger. (606 aa) |
| | mad2l2 | Mitotic arrest deficient 2 like 2. (210 aa) |
| | mcm9 | Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (1140 aa) |
| | ENSKMAP00000005281 | Uncharacterized protein. (165 aa) |
| | msh4 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (866 aa) |
| | orc4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (434 aa) |
| | msh5 | MutS homolog 5. (654 aa) |
| | slf1 | SMC5-SMC6 complex localization factor 1. (879 aa) |
| | fen1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | fsbp | RAD54 homolog B. (845 aa) |
| | gins4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) |
| | usp9x | Ubiquitin specific peptidase 9; Belongs to the peptidase C19 family. (2514 aa) |
| | mcm4 | DNA helicase; Belongs to the MCM family. (861 aa) |
| | mcm8 | Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (781 aa) |
| | rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (610 aa) |
| | rfc3 | Replication factor C (activator 1) 3. (356 aa) |
| | LOC108248076 | Checkpoint kinase 2. (534 aa) |
| | gins3 | GINS complex subunit 3. (211 aa) |
| | orc1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (695 aa) |
| | gmnn | Geminin DNA replication inhibitor. (224 aa) |
| | ENSKMAP00000009313 | Methionine sulfoxide reductase B1b. (467 aa) |
| | tp53bp1 | Tumor protein p53 binding protein, 1. (1702 aa) |
| | chtf18 | CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae). (775 aa) |
| | Rad9b | RAD9 checkpoint clamp component B. (194 aa) |
| | LOC108240516 | Centrin, EF-hand protein, 2. (177 aa) |
| | LOC108248126 | RPA_C domain-containing protein. (199 aa) |
| | pold4 | Uncharacterized protein. (110 aa) |
| | brca2 | BRCA2 DNA repair associated. (2641 aa) |
| | LOC108229664 | PMS1 homolog 1, mismatch repair system component. (568 aa) |
| | poli | Polymerase (DNA directed) iota. (716 aa) |
| | mcmbp | Minichromosome maintenance complex binding protein. (587 aa) |
| | MCMDC2 | Minichromosome maintenance domain containing 2. (637 aa) |
| | orc3 | Origin recognition complex, subunit 3. (718 aa) |
| | pms2 | PMS1 homolog 2, mismatch repair system component. (857 aa) |
| | rfc2 | Replication factor C (activator 1) 2. (357 aa) |
| | mlh1 | MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (726 aa) |
| | mcm6 | DNA helicase; Belongs to the MCM family. (823 aa) |
| | ENSKMAP00000011592 | Uncharacterized protein. (216 aa) |
| | gen1 | Chromo_2 domain-containing protein. (574 aa) |
| | recql5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (996 aa) |
| | mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (696 aa) |
| | pole3 | CBFD_NFYB_HMF domain-containing protein. (153 aa) |
| | mdc1 | Uncharacterized protein. (1989 aa) |
| | fancm | Helicase C-terminal domain-containing protein. (1616 aa) |
| | mcm10 | Minichromosome maintenance 10 replication initiation factor. (848 aa) |
| | recql4 | RecQ helicase-like 4. (1281 aa) |
| | MPHOSPH9 | Uncharacterized protein. (1272 aa) |
| | rad50 | RAD50 homolog, double strand break repair protein. (1312 aa) |
| | rad54l | RAD54 like. (739 aa) |
| | pold1 | DNA polymerase. (1105 aa) |
| | gins2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (207 aa) |
| | hus1 | Checkpoint protein; Belongs to the HUS1 family. (285 aa) |
| | LOC108228223 | Upstream binding transcription factor, like. (695 aa) |
| | pole2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa) |
| | orc5 | Origin recognition complex, subunit 5. (445 aa) |
| | rad52 | RAD52 homolog, DNA repair protein. (382 aa) |
| | rfc4 | Replication factor C (activator 1) 4. (388 aa) |
| | rad9a | Cell cycle checkpoint control protein; Belongs to the rad9 family. (387 aa) |
| | rhno1 | Si:ch73-352p4.5. (290 aa) |
| | msh2 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (934 aa) |
| | polk | Polymerase (DNA directed) kappa. (401 aa) |
| | ENSKMAP00000016201 | Uncharacterized protein. (303 aa) |
| | ENSKMAP00000016230 | Piezo_RRas_bdg domain-containing protein. (318 aa) |
| | prim1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (427 aa) |
| | mcm5 | DNA helicase; Belongs to the MCM family. (737 aa) |
| | rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (334 aa) |
| | rad51d | RAD51 paralog D. (333 aa) |
| | rpa2 | RPA_C domain-containing protein. (274 aa) |
| | exo1 | Exonuclease 1. (769 aa) |
| | tipin | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (270 aa) |
| | mcm2 | DNA helicase; Belongs to the MCM family. (890 aa) |
| | rad1 | RAD1 homolog (S. pombe). (280 aa) |
| | cdt1 | Chromatin licensing and DNA replication factor 1. (642 aa) |
| | rad51c | RAD51 paralog C. (342 aa) |
| | rpa3 | Replication protein A 14kDa subunit. (122 aa) |
| | pola1 | DNA polymerase. (1476 aa) |
| | RAD23B | RAD23 homolog B, nucleotide excision repair protein. (396 aa) |
| | bivm | Basic, immunoglobulin-like variable motif containing. (481 aa) |
| | Pole | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (298 aa) |
| | ENSKMAP00000020750 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (314 aa) |
| | top3a | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1023 aa) |
| | cdca7 | Cell division cycle associated 7a. (404 aa) |
| | rev3l | REV3 like, DNA directed polymerase zeta catalytic subunit. (2448 aa) |
| | xrcc2 | RECA_2 domain-containing protein. (357 aa) |
| | msh6 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1388 aa) |
| | timeless | Timeless circadian clock. (1247 aa) |
| | LOC108246065 | Cell division cycle 25B. (528 aa) |
| | blm | BLM RecQ like helicase. (1384 aa) |
| | pold3 | Polymerase (DNA-directed), delta 3, accessory subunit. (440 aa) |
| | exd2 | Exonuclease 3'-5' domain containing 2. (639 aa) |
| | topbp1 | DNA topoisomerase II binding protein 1. (1510 aa) |
| | lig1 | DNA ligase. (1010 aa) |
| | rad17 | RAD17 checkpoint clamp loader component. (528 aa) |
| | wdr76 | WD repeat-containing protein 76; Specifically binds 5-hydroxymethylcytosine (5hmC), suggesting that it acts as a specific reader of 5hmC. Belongs to the WD repeat DDB2/WDR76 family. (575 aa) |
| | Rbbp8 | SAE2 domain-containing protein. (82 aa) |
| | LOC108246237 | DBF4-type domain-containing protein. (741 aa) |
| | brca1 | Uncharacterized protein. (1354 aa) |
| | dscc1 | DNA replication and sister chromatid cohesion 1. (390 aa) |
| | pola2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (602 aa) |
| | prim2 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (516 aa) |
| | CLSPN | Claspin. (1213 aa) |
| | polh | Polymerase (DNA directed), eta. (738 aa) |
| | mcm7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa) |
| | mcph1 | Microcephalin 1. (817 aa) |
| | rmi2 | RecQ mediated genome instability 2. (145 aa) |
| | orc2 | Origin recognition complex, subunit 2. (585 aa) |
| | mcm3 | DNA helicase; Belongs to the MCM family. (815 aa) |
| | ercc6 | Excision repair cross-complementation group 6. (1442 aa) |
| | atrip | Uncharacterized protein. (776 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1388 aa) |
| | wdhd1 | WD repeat and HMG-box DNA binding protein 1. (954 aa) |
| | xpa | Xeroderma pigmentosum, complementation group A. (275 aa) |
| | bard1 | BRCA1 associated RING domain 1. (802 aa) |
| | rmi1 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (699 aa) |
| | atad5 | ATPase family AAA domain containing 5a. (1804 aa) |
| | fbh1 | F-box DNA helicase 1. (1108 aa) |
| | tdrd3 | Tudor domain containing 3. (787 aa) |
| | dmc1 | Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (334 aa) |
| | ercc5 | Excision repair cross-complementation group 5. (1028 aa) |
| | chek1 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. (455 aa) |
| | pole4 | Polymerase (DNA-directed), epsilon 4, accessory subunit. (130 aa) |
| | LOC108230590 | SCY domain-containing protein. (122 aa) |
