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| | rfc1 | Replication factor C subunit 1. (1180 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa) |
| | ENSKMAP00000000467 | TAN domain-containing protein. (123 aa) |
| | Atm | Uncharacterized protein. (130 aa) |
| | ENSKMAP00000001053 | Uncharacterized protein. (109 aa) |
| | rev1 | REV1 DNA directed polymerase. (1363 aa) |
| | rfc5 | Replication factor C (activator 1) 5. (339 aa) |
| | xrcc3 | DNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (343 aa) |
| | CDCA7L | zf-4CXXC_R1 domain-containing protein. (406 aa) |
| | top3b | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (858 aa) |
| | mus81 | MUS81 structure-specific endonuclease subunit. (556 aa) |
| | pold2 | Polymerase (DNA directed), delta 2, regulatory subunit. (471 aa) |
| | pcna | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa) |
| | brip1 | BRCA1 interacting protein C-terminal helicase 1. (1177 aa) |
| | LOC108244487 | Zgc:110269. (346 aa) |
| | nbn | Nibrin. (832 aa) |
| | chtf8 | CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae). (136 aa) |
| | mad2l2 | Mitotic arrest deficient 2 like 2. (210 aa) |
| | slf1 | SMC5-SMC6 complex localization factor 1. (879 aa) |
| | fen1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (380 aa) |
| | rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (610 aa) |
| | rfc3 | Replication factor C (activator 1) 3. (356 aa) |
| | LOC108248076 | Checkpoint kinase 2. (534 aa) |
| | ENSKMAP00000009313 | Methionine sulfoxide reductase B1b. (467 aa) |
| | tp53bp1 | Tumor protein p53 binding protein, 1. (1702 aa) |
| | chtf18 | CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae). (775 aa) |
| | Rad9b | RAD9 checkpoint clamp component B. (194 aa) |
| | LOC108248126 | RPA_C domain-containing protein. (199 aa) |
| | pold4 | Uncharacterized protein. (110 aa) |
| | brca2 | BRCA2 DNA repair associated. (2641 aa) |
| | poli | Polymerase (DNA directed) iota. (716 aa) |
| | rfc2 | Replication factor C (activator 1) 2. (357 aa) |
| | recql5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (996 aa) |
| | mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (696 aa) |
| | mdc1 | Uncharacterized protein. (1989 aa) |
| | fancm | Helicase C-terminal domain-containing protein. (1616 aa) |
| | recql4 | RecQ helicase-like 4. (1281 aa) |
| | rad50 | RAD50 homolog, double strand break repair protein. (1312 aa) |
| | pold1 | DNA polymerase. (1105 aa) |
| | hus1 | Checkpoint protein; Belongs to the HUS1 family. (285 aa) |
| | rad52 | RAD52 homolog, DNA repair protein. (382 aa) |
| | rfc4 | Replication factor C (activator 1) 4. (388 aa) |
| | rad9a | Cell cycle checkpoint control protein; Belongs to the rad9 family. (387 aa) |
| | rhno1 | Si:ch73-352p4.5. (290 aa) |
| | polk | Polymerase (DNA directed) kappa. (401 aa) |
| | rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (334 aa) |
| | rad51d | RAD51 paralog D. (333 aa) |
| | rpa2 | RPA_C domain-containing protein. (274 aa) |
| | rad1 | RAD1 homolog (S. pombe). (280 aa) |
| | rad51c | RAD51 paralog C. (342 aa) |
| | rpa3 | Replication protein A 14kDa subunit. (122 aa) |
| | top3a | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1023 aa) |
| | cdca7 | Cell division cycle associated 7a. (404 aa) |
| | rev3l | REV3 like, DNA directed polymerase zeta catalytic subunit. (2448 aa) |
| | xrcc2 | RECA_2 domain-containing protein. (357 aa) |
| | LOC108246065 | Cell division cycle 25B. (528 aa) |
| | blm | BLM RecQ like helicase. (1384 aa) |
| | pold3 | Polymerase (DNA-directed), delta 3, accessory subunit. (440 aa) |
| | exd2 | Exonuclease 3'-5' domain containing 2. (639 aa) |
| | topbp1 | DNA topoisomerase II binding protein 1. (1510 aa) |
| | lig1 | DNA ligase. (1010 aa) |
| | rad17 | RAD17 checkpoint clamp loader component. (528 aa) |
| | Rbbp8 | SAE2 domain-containing protein. (82 aa) |
| | brca1 | Uncharacterized protein. (1354 aa) |
| | dscc1 | DNA replication and sister chromatid cohesion 1. (390 aa) |
| | CLSPN | Claspin. (1213 aa) |
| | polh | Polymerase (DNA directed), eta. (738 aa) |
| | mcph1 | Microcephalin 1. (817 aa) |
| | rmi2 | RecQ mediated genome instability 2. (145 aa) |
| | atrip | Uncharacterized protein. (776 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1388 aa) |
| | bard1 | BRCA1 associated RING domain 1. (802 aa) |
| | rmi1 | RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (699 aa) |
| | atad5 | ATPase family AAA domain containing 5a. (1804 aa) |
| | fbh1 | F-box DNA helicase 1. (1108 aa) |
| | tdrd3 | Tudor domain containing 3. (787 aa) |
| | dmc1 | Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (334 aa) |
| | chek1 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. (455 aa) |
| | LOC108230590 | SCY domain-containing protein. (122 aa) |
