STRINGSTRING
uba6 uba6 ube2k ube2k ENSKMAP00000000992 ENSKMAP00000000992 LOC108242687 LOC108242687 LOC108230172 LOC108230172 ube2ql1 ube2ql1 sacs sacs LOC108240408 LOC108240408 LOC108242722 LOC108242722 ubr5 ubr5 LOC108247965 LOC108247965 ubr2 ubr2 LOC108250895 LOC108250895 LOC108241656 LOC108241656 trip12 trip12 c1qtnf12 c1qtnf12 pex1 pex1 pias4 pias4 LOC108250341 LOC108250341 hltf hltf sumo1 sumo1 cskmt cskmt ENSKMAP00000005692 ENSKMAP00000005692 OTUB2 OTUB2 mib2 mib2 ENSKMAP00000005965 ENSKMAP00000005965 ube2n ube2n ENSKMAP00000006147 ENSKMAP00000006147 zfand4 zfand4 LOC108236573 LOC108236573 ube2v2 ube2v2 ube2s ube2s UBE2H UBE2H LOC108229553 LOC108229553 LOC108231167 LOC108231167 LOC108251675 LOC108251675 ube2w ube2w ube2g2 ube2g2 LOC108242308 LOC108242308 LOC108239558 LOC108239558 LOC108235011 LOC108235011 LOC108248128 LOC108248128 ENSKMAP00000011723 ENSKMAP00000011723 LOC108229738 LOC108229738 ube2j1 ube2j1 traf7 traf7 LOC108242417 LOC108242417 top2a top2a LOC108242320 LOC108242320 LOC108233868 LOC108233868 ENSKMAP00000015489 ENSKMAP00000015489 trim23 trim23 ENSKMAP00000015668 ENSKMAP00000015668 LOC108237844 LOC108237844 LOC108232577 LOC108232577 rnf40 rnf40 ube2i ube2i ubb ubb UBE3A UBE3A LOC108240719 LOC108240719 LOC108250655 LOC108250655 ube3c ube3c stub1 stub1 birc6 birc6 LOC108228324 LOC108228324 LOC108235081 LOC108235081 pex6 pex6 ube2g1 ube2g1 LOC108237978 LOC108237978 LOC108229151 LOC108229151 ube2c ube2c ENSKMAP00000019873 ENSKMAP00000019873 shprh shprh rangap1 rangap1 ube2h ube2h brap brap ube2z ube2z LOC108240218 LOC108240218 zmiz1 zmiz1 LOC108245383 LOC108245383 LOC108236207 LOC108236207 LOC108248345 LOC108248345 LOC108248341 LOC108248341 LOC108240244 LOC108240244 LOC108249566 LOC108249566 rnf4 rnf4 LOC108244672 LOC108244672 rnf217 rnf217 hectd3 hectd3 LOC108235292 LOC108235292 rnf8 rnf8 arih1 arih1 ube2r2 ube2r2 uba2 uba2 ube2b ube2b LOC108229849 LOC108229849 uba1 uba1 ube2a ube2a rad18 rad18 sumo2 sumo2 top1 top1 ENSKMAP00000028779 ENSKMAP00000028779 sae1 sae1 LOC108237534 LOC108237534 ENSKMAP00000029729 ENSKMAP00000029729 LOC108232381 LOC108232381 LOC108230849 LOC108230849
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
uba6Ubiquitin like modifier activating enzyme 6. (1025 aa)
ube2kUbiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
ENSKMAP00000000992UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (186 aa)
LOC108242687Ubiquitin-conjugating enzyme E2D 1a; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
LOC108230172Ubiquitin-conjugating enzyme E2Q family member 2. (377 aa)
ube2ql1Ubiquitin-conjugating enzyme E2Q family-like 1. (299 aa)
sacsSacsin molecular chaperone. (4590 aa)
LOC108240408RAN binding protein 2. (3043 aa)
LOC108242722Small ubiquitin-related modifier. (96 aa)
ubr5Ubiquitin protein ligase E3 component n-recognin 5. (2742 aa)
LOC108247965WW domain-containing protein. (525 aa)
ubr2E3 ubiquitin-protein ligase; Ubiquitin ligase protein which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N- terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. (1629 aa)
LOC108250895Uncharacterized protein. (136 aa)
LOC108241656Uncharacterized protein. (1013 aa)
trip12Thyroid hormone receptor interactor 12. (2048 aa)
c1qtnf12C1q and TNF related 12. (322 aa)
pex1Peroxisomal biogenesis factor 1. (1251 aa)
pias4Protein inhibitor of activated STAT, 4a. (507 aa)
LOC108250341Plac8 onzin related protein 2. (128 aa)
hltfHelicase-like transcription factor. (930 aa)
sumo1Small ubiquitin-related modifier. (105 aa)
cskmtMethyltranfer_dom domain-containing protein. (261 aa)
ENSKMAP00000005692Rad60-SLD domain-containing protein. (139 aa)
OTUB2OTU deubiquitinase, ubiquitin aldehyde binding 2. (228 aa)
mib2Mindbomb E3 ubiquitin protein ligase 2. (1049 aa)
ENSKMAP00000005965DUF4200 domain-containing protein. (291 aa)
ube2nUbiquitin conjugating enzyme E2 N; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
ENSKMAP00000006147UBIQUITIN_CONJUGAT_2 domain-containing protein. (160 aa)
zfand4Zinc finger, AN1-type domain 4. (728 aa)
LOC108236573Ubiquitin-conjugating enzyme E2D 4 (putative); Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
ube2v2Ubiquitin-conjugating enzyme E2 variant 2. (145 aa)
ube2sUbiquitin-conjugating enzyme E2S; Belongs to the ubiquitin-conjugating enzyme family. (235 aa)
UBE2HUBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
LOC108229553Uncharacterized protein. (620 aa)
LOC108231167Ubiquitin-like modifier activating enzyme 7; Belongs to the ubiquitin-activating E1 family. (1013 aa)
LOC108251675Ubiquitin-conjugating enzyme E2D 3; Belongs to the ubiquitin-conjugating enzyme family. (148 aa)
ube2wUBIQUITIN_CONJUGAT_2 domain-containing protein. (169 aa)
ube2g2Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast). (92 aa)
LOC108242308SUMO specific peptidase 3b. (528 aa)
LOC108239558Cell division cycle 34 homolog (S. cerevisiae) b; Belongs to the ubiquitin-conjugating enzyme family. (238 aa)
LOC108235011UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (169 aa)
LOC108248128UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (206 aa)
ENSKMAP00000011723Uncharacterized protein. (314 aa)
LOC108229738SUMO specific peptidase 6a. (394 aa)
ube2j1Ubiquitin-conjugating enzyme E2, J1. (323 aa)
traf7TNF receptor-associated factor 7. (694 aa)
LOC108242417Ubiquitin conjugating enzyme E2 K; Belongs to the ubiquitin-conjugating enzyme family. (200 aa)
top2aDNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1539 aa)
LOC108242320E3 ubiquitin protein ligase. (1020 aa)
LOC108233868Lysine (K)-specific demethylase 6B, b. (1745 aa)
ENSKMAP00000015489HATPase_c domain-containing protein. (252 aa)
trim23Tripartite motif containing 23. (580 aa)
ENSKMAP00000015668Ubiquitin-like domain-containing protein. (85 aa)
LOC108237844Protein inhibitor of activated STAT, 1a. (698 aa)
LOC108232577Small ubiquitin-related modifier. (94 aa)
rnf40E3 ubiquitin protein ligase. (1005 aa)
ube2iUbiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
ubbUncharacterized protein. (270 aa)
UBE3AUbiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (896 aa)
LOC108240719Small ubiquitin-related modifier. (94 aa)
LOC108250655Potassium channel tetramerization domain containing 2. (265 aa)
ube3cUbiquitin protein ligase E3C. (1081 aa)
stub1STIP1 homology and U-Box containing protein 1. (284 aa)
birc6Baculoviral IAP repeat containing 6. (4869 aa)
LOC108228324UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
LOC108235081UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (153 aa)
pex6Peroxisomal biogenesis factor 6. (1024 aa)
ube2g1Ubiquitin-conjugating enzyme E2G 1a (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (170 aa)
LOC108237978Ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
LOC108229151TOP4c domain-containing protein. (301 aa)
ube2cUbiquitin-conjugating enzyme E2C; Belongs to the ubiquitin-conjugating enzyme family. (177 aa)
ENSKMAP00000019873UBIQUITIN_CONJUGAT_2 domain-containing protein. (144 aa)
shprhSNF2 histone linker PHD RING helicase. (1651 aa)
rangap1RAN GTPase activating protein 1a. (553 aa)
ube2hUbiquitin-conjugating enzyme E2H (UBC8 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family. (183 aa)
brapBRCA1 associated protein. (585 aa)
ube2zUbiquitin-conjugating enzyme E2Z. (392 aa)
LOC108240218Ubiquitin protein ligase E3A. (818 aa)
zmiz1Zinc finger MIZ-type containing 1. (1075 aa)
LOC108245383UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
LOC108236207UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
LOC108248345Uncharacterized protein. (548 aa)
LOC108248341Ubiquitin-conjugating enzyme E2L 3b; Belongs to the ubiquitin-conjugating enzyme family. (154 aa)
LOC108240244Ubiquitin-conjugating enzyme E2Q family member 1. (373 aa)
LOC108249566Ubiquitin-conjugating enzyme E2 variant 1. (147 aa)
rnf4RING-type domain-containing protein. (198 aa)
LOC108244672SP-RING-type domain-containing protein. (1109 aa)
rnf217RBR-type E3 ubiquitin transferase. (573 aa)
hectd3HECT domain containing 3. (856 aa)
LOC108235292DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (767 aa)
rnf8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (515 aa)
arih1RBR-type E3 ubiquitin transferase. (528 aa)
ube2r2Ubiquitin-conjugating enzyme E2R 2; Belongs to the ubiquitin-conjugating enzyme family. (260 aa)
uba2SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (645 aa)
ube2bUbiquitin-conjugating enzyme E2B (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family. (165 aa)
LOC108229849Protein inhibitor of activated STAT, 1b. (648 aa)
uba1Ubiquitin-like modifier activating enzyme 1; Belongs to the ubiquitin-activating E1 family. (1056 aa)
ube2aUbiquitin-conjugating enzyme E2A (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
rad18RAD18 E3 ubiquitin protein ligase. (490 aa)
sumo2Small ubiquitin-related modifier. (95 aa)
top1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (748 aa)
ENSKMAP00000028779Zinc finger, MIZ-type containing 2. (338 aa)
sae1SUMO1 activating enzyme subunit 1. (345 aa)
LOC108237534DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (746 aa)
ENSKMAP00000029729TMEM189_B_dmain domain-containing protein. (156 aa)
LOC108232381Ubiquitin conjugating enzyme E2 A, like; Belongs to the ubiquitin-conjugating enzyme family. (152 aa)
LOC108230849Cell division cycle 34 homolog (S. cerevisiae) a; Belongs to the ubiquitin-conjugating enzyme family. (242 aa)
Your Current Organism:
Kryptolebias marmoratus
NCBI taxonomy Id: 37003
Other names: K. marmoratus, Rivulus marmoratus, mangrove rivulus, matanzas rivulus
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