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| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa) |
| | pole4 | Polymerase (DNA-directed), epsilon 4, accessory subunit. (130 aa) |
| | chek1 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. (455 aa) |
| | haus5 | SIN3 transcription regulator family member B. (1260 aa) |
| | ENSKMAP00000030004 | Uncharacterized protein. (80 aa) |
| | nfrkb | Nuclear factor related to kappaB binding protein. (1278 aa) |
| | dmap1 | DNA methyltransferase 1 associated protein 1. (483 aa) |
| | smc2 | Structural maintenance of chromosomes protein. (1200 aa) |
| | dmc1 | Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (334 aa) |
| | syce2 | Uncharacterized protein. (152 aa) |
| | wdhd1 | WD repeat and HMG-box DNA binding protein 1. (954 aa) |
| | smc4 | Structural maintenance of chromosomes protein. (1255 aa) |
| | smc3 | Structural maintenance of chromosomes protein. (1218 aa) |
| | ENSKMAP00000026824 | E1A binding protein p400. (1515 aa) |
| | ruvbl1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | slx4 | SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1695 aa) |
| | CCNB1IP1 | Cyclin B1 interacting protein 1. (311 aa) |
| | mcm3 | DNA helicase; Belongs to the MCM family. (815 aa) |
| | BAZ1A | Bromodomain adjacent to zinc finger domain 1A. (1068 aa) |
| | ino80 | INO80 complex ATPase subunit. (1474 aa) |
| | orc2 | Origin recognition complex, subunit 2. (585 aa) |
| | sirt7 | Sirtuin 7. (406 aa) |
| | mcm7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (727 aa) |
| | ENSKMAP00000025497 | Peptidylprolyl isomerase. (217 aa) |
| | LOC108238083 | H2A histone family, member Y; Belongs to the histone H2A family. (369 aa) |
| | prim2 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (516 aa) |
| | pola2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (602 aa) |
| | brca1 | Uncharacterized protein. (1354 aa) |
| | setd5 | SET domain containing 5. (1429 aa) |
| | psmc3ip | PSMC3 interacting protein. (212 aa) |
| | Nek2 | NIMA-related kinase 2. (492 aa) |
| | ENSKMAP00000024065 | Helicase ATP-binding domain-containing protein. (279 aa) |
| | lrwd1 | Leucine-rich repeats and WD repeat domain containing 1. (730 aa) |
| | sycp3 | Synaptonemal complex protein 3. (236 aa) |
| | topbp1 | DNA topoisomerase II binding protein 1. (1510 aa) |
| | LOC108239168 | Core histone macro-H2A; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. (370 aa) |
| | pold3 | Polymerase (DNA-directed), delta 3, accessory subunit. (440 aa) |
| | blm | BLM RecQ like helicase. (1384 aa) |
| | mcrs1 | Microspherule protein 1. (466 aa) |
| | timeless | Timeless circadian clock. (1247 aa) |
| | ino80d | INO80 complex subunit Da. (1000 aa) |
| | ENSKMAP00000021195 | Si:dkey-40g16.5. (134 aa) |
| | cdca7 | Cell division cycle associated 7a. (404 aa) |
| | ENSKMAP00000020750 | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (314 aa) |
| | Pole | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (298 aa) |
| | LOC108244223 | Structural maintenance of chromosomes 1B. (1046 aa) |
| | phf12 | PHD finger protein 12b. (975 aa) |
| | pola1 | DNA polymerase. (1476 aa) |
| | rpa3 | Replication protein A 14kDa subunit. (122 aa) |
| | cpsf6 | Cleavage and polyadenylation specific factor 6. (582 aa) |
| | sycp2 | Uncharacterized protein. (1035 aa) |
| | smchd1 | Structural maintenance of chromosomes flexible hinge domain containing 1. (1800 aa) |
| | sap130 | Sin3A-associated protein a. (1047 aa) |
| | rad1 | RAD1 homolog (S. pombe). (280 aa) |
| | ENSKMAP00000019407 | Uncharacterized protein. (95 aa) |
| | ruvbl2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (459 aa) |
| | LOC108229143 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (368 aa) |
| | mcm2 | DNA helicase; Belongs to the MCM family. (890 aa) |
| | tipin | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (270 aa) |
| | ENSKMAP00000018800 | Uncharacterized protein. (523 aa) |
| | spo11 | SPO11 initiator of meiotic double stranded breaks. (374 aa) |
| | zranb3 | Zinc finger, RAN-binding domain containing 3. (984 aa) |
| | rcc1 | Regulator of chromosome condensation 1. (420 aa) |
| | pinx1 | PIN2 (TERF1) interacting telomerase inhibitor 1. (364 aa) |
| | rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (334 aa) |
| | mcm5 | DNA helicase; Belongs to the MCM family. (737 aa) |
| | actr5 | Actin related protein 5; Belongs to the actin family. (642 aa) |
| | prim1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (427 aa) |
| | uchl5 | Ubiquitin carboxyl-terminal hydrolase. (329 aa) |
| | smarcal1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (868 aa) |
| | swi5 | SWI5 homologous recombination repair protein. (136 aa) |
| | rad9a | Cell cycle checkpoint control protein; Belongs to the rad9 family. (387 aa) |
| | actr8 | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (643 aa) |
| | Kmt2e | Lysine (K)-specific methyltransferase 2E. (430 aa) |
| | ing3 | Inhibitor of growth protein. (418 aa) |
| | orc5 | Origin recognition complex, subunit 5. (445 aa) |
| | pole2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (528 aa) |
| | LOC108229000 | Acidic (leucine-rich) nuclear phosphoprotein 32 family, member E. (249 aa) |
| | LOC108247556 | Kinesin-associated protein 3a. (780 aa) |
| | prpf19 | Pre-mRNA processing factor 19. (505 aa) |
| | hus1 | Checkpoint protein; Belongs to the HUS1 family. (285 aa) |
| | gins2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (207 aa) |
| | pold1 | DNA polymerase. (1105 aa) |
| | Syce3 | Uncharacterized protein. (83 aa) |
| | rad50 | RAD50 homolog, double strand break repair protein. (1312 aa) |
| | mcm10 | Minichromosome maintenance 10 replication initiation factor. (848 aa) |
| | ino80e | INO80 complex subunit E. (250 aa) |
| | LOC108239531 | Kinesin-associated protein 3b. (777 aa) |
| | pole3 | CBFD_NFYB_HMF domain-containing protein. (153 aa) |
| | tonsl | Tonsoku-like, DNA repair protein. (1413 aa) |
| | mcm6 | DNA helicase; Belongs to the MCM family. (823 aa) |
| | mlh1 | MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (726 aa) |
| | orc3 | Origin recognition complex, subunit 3. (718 aa) |
| | znhit1 | Zinc finger, HIT-type containing 1. (156 aa) |
| | Rrs1 | Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (339 aa) |
| | trrap | Transformation/transcription domain-associated protein; Belongs to the PI3/PI4-kinase family. (3820 aa) |
| | LOC108251067 | SIN3 transcription regulator family member Aa. (1262 aa) |
| | brms1l | Uncharacterized protein. (251 aa) |
| | brca2 | BRCA2 DNA repair associated. (2641 aa) |
| | actr6 | Actin related protein 6; Belongs to the actin family. (295 aa) |
| | pold4 | Uncharacterized protein. (110 aa) |
| | brms1 | BRMS1 transcriptional repressor and anoikis regulator. (277 aa) |
| | Rad9b | RAD9 checkpoint clamp component B. (194 aa) |
| | orc1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (695 aa) |
| | ncaph | Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (692 aa) |
| | atrx | ATRX chromatin remodeler. (2228 aa) |
| | LOC108240254 | Uncharacterized protein. (137 aa) |
| | gins3 | GINS complex subunit 3. (211 aa) |
| | sinhcaf | SIN3-HDAC complex associated factor. (338 aa) |
| | hmga2 | Uncharacterized protein. (115 aa) |
| | LOC108247429 | Uncharacterized protein. (1905 aa) |
| | LOC108242278 | Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (261 aa) |
| | rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (610 aa) |
| | ino80c | INO80 complex subunit C. (207 aa) |
| | ENSKMAP00000007253 | HORMA domain-containing protein. (90 aa) |
| | SPIDR | Scaffold protein involved in DNA repair. (938 aa) |
| | smc1a | Structural maintenance of chromosomes protein. (1231 aa) |
| | mcm4 | DNA helicase; Belongs to the MCM family. (861 aa) |
| | gins4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) |
| | nol6 | Nucleolar protein 6. (1150 aa) |
| | tfpt | TCF3 (E2A) fusion partner. (197 aa) |
| | LOC108250642 | SIN3-HDAC complex associated factor, like. (224 aa) |
| | orc4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (434 aa) |
| | srcap | Snf2-related CREBBP activator protein. (2762 aa) |
| | msh4 | DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (866 aa) |
| | LOC108231751 | BRMS1 like transcriptional repressor b. (324 aa) |
| | LOC108242792 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1; Belongs to the SNF5 family. (373 aa) |
| | cdc45 | CDC45 cell division cycle 45 homolog (S. cerevisiae). (572 aa) |
| | lrpprc | Leucine-rich pentatricopeptide repeat containing. (1644 aa) |
| | tex11 | Testis expressed 11. (806 aa) |
| | pold2 | Polymerase (DNA directed), delta 2, regulatory subunit. (471 aa) |
| | mlh3 | MutL homolog 3 (E. coli). (1121 aa) |
| | rsph1 | Uncharacterized protein. (217 aa) |
| | gins1 | GINS complex subunit 1 (Psf1 homolog). (196 aa) |
| | mms22l | MMS22-like, DNA repair protein. (1212 aa) |
| | LOC108234793 | SIN3 transcription regulator family member Ab. (1289 aa) |
| | wapl | WAPL cohesin release factor a. (1187 aa) |
| | suds3 | SDS3 homolog, SIN3A corepressor complex component. (352 aa) |
| | CDCA7L | zf-4CXXC_R1 domain-containing protein. (406 aa) |
| | LOC108250252 | WAPL cohesin release factor b. (1220 aa) |
| | nufip1 | C2H2-type domain-containing protein. (561 aa) |
| | LOC108243912 | Acidic (leucine-rich) nuclear phosphoprotein 32 family, member E. (247 aa) |
| | ncapg | Non-SMC condensin I complex, subunit G. (1016 aa) |
